Published in Nature on November 02, 1978
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Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines. Proc Natl Acad Sci U S A (1981) 1.50
O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication. Proc Natl Acad Sci U S A (1986) 1.41
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Evidence for removal at different rates of O-ethyl pyrimidines and ethylphosphotriesters in two human fibroblast cell lines. Nucleic Acids Res (1979) 1.14
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Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea. Proc Natl Acad Sci U S A (1990) 0.94
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All oxygens in nucleic acids react with carcinogenic ethylating agents. Nature (1976) 2.16
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Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells. Proc Natl Acad Sci U S A (1976) 1.97
Repair replication, unscheduled DNA synthesis, and the repair of mammalian DNA. Radiat Res (1969) 1.93
Genomic insight into the amino acid relations of the pea aphid, Acyrthosiphon pisum, with its symbiotic bacterium Buchnera aphidicola. Insect Mol Biol (2010) 1.92
DNA damage and repair in light-sensitive human skin disease. J Invest Dermatol (1970) 1.87
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Xeroderma pigmentosum: variants with normal DNA repair and normal sensitivity to ultraviolet light. J Invest Dermatol (1972) 1.84
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The synthesis of 4-methylumbelliferyl alpha-ketoside of N-acetylneuraminic acid and its use in a fluorometric assay for neuraminidase. Anal Biochem (1980) 1.78
Single strand interruptions in DNA and the effects of caffeine in Chinese hamster cells irradiated with ultraviolet light. Biochem Biophys Res Commun (1969) 1.77
A screening method for isolating DNA repair-deficient mutants of CHO cells. Somatic Cell Genet (1980) 1.77
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The tripartite ATP-independent periplasmic (TRAP) transporters of bacteria and archaea. FEMS Microbiol Rev (2001) 1.72
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair. Radiat Res (1969) 1.66
High-LET radiations induce a large proportion of non-rejoining DNA breaks. Nature (1977) 1.64
NADP-linked 17-beta- and 20-alpha-steroid reductase activity in the rabbit uterus. J Endocrinol (1969) 1.64
Investigations into the incorporation of [3H] thymidine into DNA in L-strain cells and the formation of a pool of phosphorylated derivaives during pulse labelling. Biochim Biophys Acta (1965) 1.64
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Gender differences in age-related changes in HPA axis reactivity. Psychoneuroendocrinology (2001) 1.60
O2- and O4-alkyl pyrimidine nucleosides: stability of the glycosyl bond and of the alkyl group as a function of pH. Biochemistry (1978) 1.60
Xeroderma pigmentosum. Clinical and laboratory investigation of its basic defect. JAMA (1969) 1.57
Repair replication in HeLa cells after large doses of x-irradiation. Nature (1967) 1.55
Familial tandem duplication of bands q31.1 to q32.3 on chromosome 4 with mild phenotypic effect. Am J Med Genet (1997) 1.54
O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine. Proc Natl Acad Sci U S A (1984) 1.54
Complex chromosome rearrangements. Report of a new case and literature review. Clin Genet (1980) 1.51
Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair. EMBO J (1988) 1.51
Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines. Proc Natl Acad Sci U S A (1981) 1.50
Large-scale isolation of UV-sensitive clones of CHO cells. Somatic Cell Genet (1980) 1.48
Mucolipidosis III (pseudo-Hurler polydystrophy): Clinical and laboratory studies in a series of 12 patients. Johns Hopkins Med J (1975) 1.48
Absence of excision of ultraviolet-induced cyclobutane dimers in xeroderma pigmentosum. Photochem Photobiol (1970) 1.46
Preparation and template activities of polynucleotides containing O2- and O4-alkyluridine. Proc Natl Acad Sci U S A (1978) 1.46
Black/white differences in health status and mortality among the elderly. Demography (1989) 1.46
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. Proc Natl Acad Sci U S A (1986) 1.45
Syndromes due to chromosomal abnormalities: partial trisomy 22, interstitial deletion of the long arm of 13, and trisomy 8. Johns Hopkins Med J (1979) 1.45
Sequence specificity of cyclobutane pyrimidine dimers in DNA treated with solar (ultraviolet B) radiation. Nucleic Acids Res (1992) 1.45
Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblasts. J Mol Biol (1981) 1.44
Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc Natl Acad Sci U S A (1997) 1.44
Purified scrapie prions resist inactivation by UV irradiation. J Virol (1987) 1.43
In vitro studies of cell proliferation in tumours. II. Characteristics of a standardised in vitro system for the measurement of 3H-thymidine incorporation into tissue explants. Eur J Cancer (1965) 1.43
Competition between Escherichia coli strains expressing either a periplasmic or a membrane-bound nitrate reductase: does Nap confer a selective advantage during nitrate-limited growth? Biochem J (1999) 1.42
Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis. Proc Natl Acad Sci U S A (1983) 1.41
The sodium-retaining effect of renal nerve activity in the cat: role of angiotensin formation. Clin Sci Mol Med (1976) 1.41
O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication. Proc Natl Acad Sci U S A (1986) 1.41
Ashkenazi-Jewish and non-Jewish adult GM2 gangliosidosis patients share a common genetic defect. Am J Hum Genet (1990) 1.40
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. Proc Natl Acad Sci U S A (1991) 1.38
Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage. Proc Natl Acad Sci U S A (1991) 1.37
Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats. J Mol Biol (1990) 1.35
O-alkyl pyrimidines in mutagenesis and carcinogenesis: occurrence and significance. Cancer Res (1986) 1.33
Climate change. Preparing for resettlement associated with climate change. Science (2011) 1.32
1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase). Biochemistry (1994) 1.31
Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells. Exp Cell Res (1972) 1.31
Estimation of gestational age of African newborn infants by a scoring system. S Afr Med J (1973) 1.30
All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. Proc Natl Acad Sci U S A (1994) 1.29
Mannosidosis: deficiency of a specific alpha-mannosidase component in cultured fibroblasts. Clin Chim Acta (1975) 1.29
Reaction of guanosine with ethylating agents. Biochemistry (1972) 1.28
Nonrandom induction of pyrimidine-pyrimidone (6-4) photoproducts in ultraviolet-irradiated human chromatin. J Biol Chem (1990) 1.27
Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences. Biochemistry (1991) 1.26
Deposition of scar tissue in the central nervous system. Acta Neurochir Suppl (Wien) (1983) 1.26
Sedimentation of DNA from human fibroblasts irradiated with ultraviolet light: possible detection of excision breaks in normal and repair-deficient xeroderma pigmentosum cells. Radiat Res (1974) 1.26
Neoplastic transformation of fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo. J Natl Cancer Inst (1975) 1.26
Solubility and dialysis limits of DNA oligonucleotides. Biochim Biophys Acta (1972) 1.26
Increased levels of sialic acid associated with a sialidase deficiency in I-cell disease (mucolipidosis II) fibroblasts. Biochem Biophys Res Commun (1976) 1.26
Reaction of diazoalkanes with 1-substituted 2, 4-dioxopyrimidines. Formation of O2, N-3 and O4-alkyl products. Nucleic Acids Res (1976) 1.26
Nucleosome structure controls rates of excision repair in DNA of human cells. Nature (1977) 1.25
DNA repair and radiation sensitivity in human (xeroderma pigmentosum) cells. Int J Radiat Biol Relat Stud Phys Chem Med (1970) 1.25
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol (1974) 1.24
Excision repair of ultraviolet damage in mammalian cells. Evidence for two steps in the excision of pyrimidine dimers. Biophys J (1978) 1.24
Cryptic terminal rearrangement of chromosome 22q13.32 detected by FISH in two unrelated patients. J Med Genet (1997) 1.24
Early discharge of infants of low birth weight: a prospective study. Br Med J (1975) 1.24
Biological damage from intranuclear tritium: DNA strand breaks and their repair. Science (1972) 1.24
Effect of renal nerve stimulation, renal blood flow and adrenergic blockade on plasma renin activity in the cat. J Physiol (1972) 1.24
Genetic complementation after fusion of Tay-Sachs and Sandhoff cells. Nature (1974) 1.22
Photoraactivation: a radiation repair mechanism absent from mammalian cells. Biochem Biophys Res Commun (1966) 1.20
Chemical modification of viral RNA. VI. The action of N-methyl-N'-nitro-N-nitrosoguanidine. Proc Natl Acad Sci U S A (1967) 1.20
Human cells contain protein specifically binding to a single 1,N6-ethenoadenine in a DNA fragment. Proc Natl Acad Sci U S A (1991) 1.19
High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos. Methods Cell Biol (1994) 1.17
O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer. Int J Cancer (1985) 1.17