Published in Antimicrob Agents Chemother on July 01, 1995
Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet (1989) 2.54
Pivampicillin-promoted excretion of pivaloylcarnitine in humans. Biochem Pharmacol (1987) 1.50
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores. Antimicrob Agents Chemother (1992) 1.25
Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans. Antimicrob Agents Chemother (1992) 1.20
Differential excretion of xenobiotic acyl-esters of carnitine due to administration of pivampicillin and valproate. Biochem Med Metab Biol (1990) 1.07
Simple and reliable method for serial sampling of blood from rats. J Pharm Sci (1975) 1.01
Carnitine and glucuronic acid conjugates of pivalic acid. Xenobiotica (1985) 0.95
Carnitine status and safety after administration of S-1108, a new oral cephem, to patients. Antimicrob Agents Chemother (1993) 0.90
Effects of pivalic acid-containing prodrugs on carnitine homeostasis and on response to fasting in children. Scand J Clin Lab Invest (1992) 0.89
Environmental degradation of the miticide cycloprate (hexadecyl cyclopropanecarboxylate). 4. Beagle dog metabolism. J Agric Food Chem (1978) 0.87
Preferential elimination of pivalate with supplemental carnitine via formation of pivaloylcarnitine in man. Xenobiotica (1993) 0.83
Reduced carnitine and ketogenesis in the pivampicillin treated rat. Biochem Pharmacol (1992) 0.82
Hepatic UDP-glucuronic acid regulation during acetaminophen biotransformation in rats. J Pharmacol Exp Ther (1986) 0.81
pH dependent formation of beta-glucuronidase resistant conjugates from the biosynthetic ester glucuronide of isoxepac. Biochem Pharmacol (1981) 0.81
Separation of two conjugates of clofibric acid (CPIB) found in the urine of subjects taking clofibrate. Clin Exp Pharmacol Physiol (1978) 0.79
Effect of valproic acid on glycine conjugation of benzoic acid. J Pharmacol Exp Ther (1993) 0.79
Isolation and identification of probenecid acyl glucuronide. J Pharm Pharmacol (1981) 0.79
Synthesis and structure-activity relationships of 7 beta-[(Z)-2-(2- aminothiazol-4-yl)-3-(substituted)-2-propenoylamino]-3-cephems with C-3 substitutions. J Antibiot (Tokyo) (1994) 0.79
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol (2001) 13.98
A protein conjugation system essential for autophagy. Nature (1998) 12.71
Formation process of autophagosome is traced with Apg8/Aut7p in yeast. J Cell Biol (1999) 9.33
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct Funct (1998) 9.18
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol (2000) 7.48
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep (2001) 7.13
LDL-receptor-related proteins in Wnt signal transduction. Nature (2000) 6.94
A restriction map of the bacteriophage T4 genome. Mol Gen Genet (1980) 6.37
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. J Biol Chem (1998) 5.07
Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice. Genes Dev (2000) 4.38
A new enzymatic method for determination of serum choline-containing phospholipids. Clin Chim Acta (1977) 3.44
Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion. Mol Biol Cell (2001) 3.41
Initiation of Sendai virus multiplication from transfected cDNA or RNA with negative or positive sense. Genes Cells (1996) 3.41
CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Genes Dev (1996) 3.27
Characterization of oligonucleotide transport into living cells. Proc Natl Acad Sci U S A (1989) 3.27
NAK is an IkappaB kinase-activating kinase. Nature (2000) 2.44
Molecular cloning of engrailed: a gene involved in the development of pattern in Drosophila melanogaster. Cell (1985) 2.26
Antitumor action of some Basidiomycetes, especially Phllinus linteus. Gan (1968) 2.25
A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome. EMBO J (2001) 2.22
Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion. J Cell Sci (1995) 2.20
Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem (2001) 2.15
Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet disease. Proc Natl Acad Sci U S A (1997) 2.10
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ (2008) 1.99
A Japanese family of X-linked auto-immune enteropathy with haemolytic anaemia and polyendocrinopathy. Eur J Pediatr (1993) 1.99
Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid. J Cell Biol (1998) 1.85
Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85
The anticancer drug imatinib induces cellular autophagy. Leukemia (2007) 1.84
Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation. Br J Cancer (2001) 1.77
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene. Proc Natl Acad Sci U S A (1988) 1.70
Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase. Oncogene (1999) 1.68
Hepatitis B virus genotype distribution among chronic hepatitis B virus carriers in Shanghai, China. Intervirology (2001) 1.65
Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene. Hum Mol Genet (1999) 1.60
Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors. Mol Cell Biol (1990) 1.52
Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells. J Biol Chem (2001) 1.51
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. Mol Cell Biol (2001) 1.51
Rotavirus NSP4 induces a novel vesicular compartment regulated by calcium and associated with viroplasms. J Virol (2006) 1.49
Helicobacter pylori infection in rheumatoid arthritis: effect of drugs on prevalence and correlation with gastroduodenal lesions. Rheumatology (Oxford) (2002) 1.48
Binding of cytotoxic T-lymphocytes to supported lipid monolayers containing trypsinized H-2Kk. Mol Immunol (1983) 1.47
Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53. J Biol Chem (1999) 1.47
The late stages of autophagy: how does the end begin? Cell Death Differ (2009) 1.47
Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cells. J Biol Chem (2000) 1.46
Super high resolution for single molecule-sequence-based typing of classical HLA loci at the 8-digit level using next generation sequencers. Tissue Antigens (2012) 1.44
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors. Proc Natl Acad Sci U S A (2000) 1.44
The inductive effect of interleukin-4 on IgG4 and IgE synthesis in human peripheral blood lymphocytes. Clin Exp Immunol (1990) 1.43
Amplification and over-expression of the AIB1 nuclear receptor co-activator gene in primary gastric cancers. Int J Cancer (2000) 1.43
Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure (1996) 1.42
The critical region for Behçet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping. Am J Hum Genet (1999) 1.41
Localization of the pathogenic gene of Behçet's disease by microsatellite analysis of three different populations. Invest Ophthalmol Vis Sci (2000) 1.40
Venous malformation of the vulva. BJOG (2001) 1.39
Association of thrombosis-inducing activity (TIA) with fatal hypercoagulable complications in patients with lung cancer. Chest (1994) 1.39
Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein. Mol Cell Biol (1996) 1.37
A method of drusen measurement based on reconstruction of fundus background reflectance. Br J Ophthalmol (2005) 1.36
CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding. J Biol Chem (2001) 1.34
Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder. Biochem J (1994) 1.32
Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method. J Biol Chem (1991) 1.30
Protective effects of 1 alpha,25-(OH)(2)D(3) against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture. Neuropharmacology (2001) 1.27
Spiral CT findings in septic pulmonary emboli. Eur J Radiol (2001) 1.26
Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase. Arch Biochem Biophys (1992) 1.21
Hydrogen--deuterium exchange study of amino acids and proteins by 200- to 230-nm spectroscopy. Anal Biochem (1981) 1.21
Cellular origin of fundus autofluorescence in patients and mice with a defective NR2E3 gene. Br J Ophthalmol (2009) 1.21
Exposure of DNA bases induced by the interaction of DNA and calf thymus DNA helix-destabilizing protein. Proc Natl Acad Sci U S A (1978) 1.19
Nasal cavity vascular leiomyoma: case report and literature review. Braz J Otorhinolaryngol (2008) 1.18
Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain-related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian. Tissue Antigens (1997) 1.14
Occult lymph node metastases detected by cytokeratin immunohistochemistry predict recurrence in node-negative endometrial cancer. Gynecol Oncol (2001) 1.13
Direct neurite-mast cell communication in vitro occurs via the neuropeptide substance P. J Immunol (1999) 1.12
Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochem Biophys Res Commun (1987) 1.12
Antitumor activity of aqueous extracts of edible mushrooms. Cancer Res (1969) 1.12
A correlation between the secondary structure of DNA and the reactivity of adenine residues with chloroacetaldehyde. J Biochem (1977) 1.10
A novel human gene encoding HECT domain and RCC1-like repeats interacts with cyclins and is potentially regulated by the tumor suppressor proteins. Biochem Biophys Res Commun (1999) 1.10
A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region. Genomics (2001) 1.10
Stopped-flow ultraviolet spectroscopy for hydrogen-exchange studies of nucleic acids. FEBS Lett (1977) 1.10
Chromosomal aberrations in colorectal cancers and liver metastases analyzed by comparative genomic hybridization. Int J Cancer (2001) 1.09
Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons. FASEB J (2000) 1.08
Cyclin E as a coactivator of the androgen receptor. J Cell Biol (2000) 1.08
Role of the serotonin3 receptor in stress-induced defecation. J Pharmacol Exp Ther (1992) 1.07
Two types of mu chain complexes are expressed during differentiation from pre-B to mature B cells. EMBO J (1990) 1.06
Two channels of hydrogen exchange in a double-helical nucleic acid. J Mol Biol (1978) 1.06
A new colorimetric method for the determination of plasma lecithin-cholesterol acyltransferase activity. Clin Chim Acta (1977) 1.04
Expression and kinetic properties of a recombinant 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzyme of human liver. J Biochem (1995) 1.04
Radiographic findings and prognosis of simple bone cysts of the jaws. Dentomaxillofac Radiol (2010) 1.03
Antibodies for fluorescent molecular rotors. Biochemistry (1993) 1.03
The nerve fibre constitution of the nerves of the eye. J Physiol (1924) 1.03
Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients. Gut (2006) 1.02
ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin. Oncogene (2007) 1.01
Protein disulfide isomerase associates with misfolded human lysozyme in vivo. J Biol Chem (1994) 1.01
Dynamics of intracellular granules with CD63-GFP in rat basophilic leukemia cells. J Biochem (2001) 1.01
Association of MICA gene and HLA-B*5101 with Behçet's disease in Greece. Invest Ophthalmol Vis Sci (1999) 1.00
Inhibitors of vacuolar-type H(+)-ATPase suppresses proliferation of cultured cells. J Cell Physiol (1993) 1.00
A selective signaling defect in helper T cells induced by antigen-presenting cells from mice with murine acquired immunodeficiency syndrome. J Immunol (1990) 1.00
Carbohydrate structures of HVJ (Sendai virus) glycoproteins. J Biol Chem (1981) 1.00
Characterization of the amyR gene encoding a transcriptional activator for the amylase genes in Aspergillus nidulans. Curr Genet (2001) 1.00
Rat basophilic leukemia cells express syntaxin-3 and VAMP-7 in granule membranes. Biochem Biophys Res Commun (2000) 0.99
Twenty-six new polymorphic microsatellite markers around the HLA-B, -C and -E loci in the human MHC class I region. Tissue Antigens (1998) 0.98
Status of soil-transmitted helminthic infection in Nepal. Kansenshogaku Zasshi (1994) 0.98
Spatially and temporally regulated expression of the LIM class homeobox gene Hrlim suggests multiple distinct functions in development of the ascidian, Halocynthia roretzi. Mech Dev (1995) 0.98
Positional changes of oropharyngeal structures due to gravity in the upright and supine positions. Dentomaxillofac Radiol (2008) 0.98
The pilot trial of the prevention of the increase in electrical taste thresholds by zinc containing fluid infusion during chemotherapy to treat primary lung cancer. J Exp Clin Cancer Res (2003) 0.97
Effect of intestinal helminth infection on some nutritional parameters among rural villagers in Nepal. Kobe J Med Sci (1998) 0.97