Published in J Biol Chem on October 28, 1994
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol Cell Biol (1997) 2.67
Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talin. J Cell Biol (1999) 1.70
Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain. Biochem J (1996) 1.55
Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood (2005) 1.44
Thrombospondin modulates alpha v beta 3 function through integrin-associated protein. J Cell Biol (1996) 1.43
Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model. J Cell Biol (1999) 1.29
Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. Blood (2006) 1.22
Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood (2005) 1.21
Localization of the adhesion receptor glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activation. J Exp Med (2002) 1.20
A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood (2005) 1.20
Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family. Biochem J (1995) 1.14
Future innovations in anti-platelet therapies. Br J Pharmacol (2008) 1.13
Interaction of Ras with phosphoinositide 3-kinase gamma. Biochem J (1997) 1.05
Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway. Biochem J (2002) 0.92
Bidirectional integrin alphaIIbbeta3 signalling regulating platelet adhesion under flow: contribution of protein kinase C. Biochem J (2003) 0.86
Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets. Platelets (2005) 0.85
The effect of upstream platelet-fibrinogen interactions on downstream adhesion and activation. Biomaterials (2011) 0.82
Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk. Biochem J (2000) 0.81
Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signaling. Int J Mol Sci (2012) 0.76
The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3)-binder Rasa3 Regulates Phosphoinositide 3-kinase (PI 3-kinase)-dependent Integrin αIIbβ3 Outside-in Signaling. J Biol Chem (2016) 0.75
Involvement of the glycoproteic Ib-V-IX complex in nickel-induced platelet activation. Environ Health Perspect (2001) 0.75
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature (2000) 32.30
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature (2000) 7.66
A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus. Proc Natl Acad Sci U S A (1998) 6.76
Predicting function: from genes to genomes and back. J Mol Biol (1998) 6.60
Studies in Equine Encephalomyelitis: Chick Embryo Vaccine as a Protective Agent. Can J Comp Med (1938) 3.44
Enrichment of gene-coding sequences in maize by genome filtration. Science (2003) 3.41
Differences in genotypes of Helicobacter pylori from different human populations. J Bacteriol (2000) 3.39
Identification of the immediate-early transcripts of Kaposi's sarcoma-associated herpesvirus. J Virol (1999) 3.33
Mycolic acids: structure, biosynthesis and physiological functions. Prog Lipid Res (1998) 3.21
Disparate responses to oxidative stress in saprophytic and pathogenic mycobacteria. Proc Natl Acad Sci U S A (1995) 3.18
Preliminary Experiments Relating to the Propagation of Viruses in the Bovine Mammary Gland. Can J Comp Med Vet Sci (1953) 2.83
Interviewing prepubertal children about suicidal ideation and behavior. J Am Acad Child Adolesc Psychiatry (1994) 2.66
Studies in Newcastle Disease: II. Inactiated Virus and Adjuvant used as Vaccine. Can J Comp Med Vet Sci (1951) 2.58
Early Veterinary History. Can J Comp Med (1938) 2.57
Further Experiments Relating to the Propagation of Virus in the Bovine Mammary Gland. Can J Comp Med Vet Sci (1953) 2.51
Buteyko breathing techniques in asthma: a blinded randomised controlled trial. Med J Aust (1999) 2.42
Protocol for emergency EPR dosimetry in fingernails. Radiat Meas (2007) 2.41
The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2. J Biol Chem (1995) 2.40
EPR dosimetry in chemically treated fingernails. Radiat Meas (2007) 2.33
Guide wire-assisted cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. Endoscopy (2013) 2.15
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol (2015) 2.07
Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays. Circulation (2000) 2.04
Early Veterinary History : Sir William Osler. Can J Comp Med (1939) 2.04
Prucalopride in the treatment of chronic constipation in patients from the Asia-Pacific region: a randomized, double-blind, placebo-controlled study. Neurogastroenterol Motil (2012) 2.03
Decay of influenza A viruses of human and avian origin. Can J Comp Med (1968) 2.00
Viability of Brucella Abortus Strain 19. Can J Comp Med Vet Sci (1942) 1.99
Antibody production in milk serum after virus instillation of goat mammary gland. I. Responses to influenza virus, mumps virus, and adenovirus 3. Can J Microbiol (1967) 1.82
Effect of low- and high-frequency TENS on Met-enkephalin-Arg-Phe and dynorphin A immunoreactivity in human lumbar CSF. Pain (1991) 1.79
Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori. J Bacteriol (2000) 1.77
Asthma morbidity in Australia: an epidemiological study. Med J Aust (1992) 1.74
Does the intraesophageal pH probe accurately detect acid reflux? Simultaneous recording with two pH probes in humans. Dig Dis Sci (1989) 1.72
Measuring the systemic effects of inhaled beclomethasone: timed morning urine collections compared with 24 hour specimens. Thorax (1995) 1.72
VEGF induces NO-dependent hyperpermeability in coronary venules. Am J Physiol (1996) 1.70
Early Veterinary History. Can J Comp Med (1939) 1.70
The Chlamydia trachomatis hyp operon is homologous to the groE stress response operon of Escherichia coli. Infect Immun (1990) 1.67
Aeromonas hydrophila septicemia. Am J Dis Child (1972) 1.65
A poroelastic finite element formulation including transport and swelling in soft tissue structures. J Biomech Eng (1996) 1.64
Early Veterinary History. Can J Comp Med (1939) 1.61
Homology-based fold predictions for Mycoplasma genitalium proteins. J Mol Biol (1998) 1.60
Asthma management in eastern Australia, 1990 and 1993. Med J Aust (1996) 1.59
DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma. Oncogene (2000) 1.56
Electron paramagnetic resonance in human fingernails: the sponge model implication. Radiat Environ Biophys (2008) 1.55
Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain. Biochem J (1996) 1.55
Isolation and characterization of thrombomodulin from human placenta. J Biol Chem (1984) 1.50
Protease inhibitor exposure and increased risk of cardiovascular disease in HIV-infected patients. HIV Med (2005) 1.49
Audit of consultant physicians' reply letters for referrals to clinics in a tertiary teaching hospital. Intern Med J (2004) 1.49
Vaccination of Sexually Mature Cows with Brucella abortus Strain 19: I. Negative Cows Contained in Negative Dairy Herds. Can J Comp Med Vet Sci (1948) 1.46
A national policy on asthma management for schools. The Asthma Special Interest Group, Thoracic Society of Australia and New Zealand. J Paediatr Child Health (1994) 1.45
Effect of casein phosphopeptide-amorphous calcium phosphate added to acidic beverages on enamel erosion in vitro. Aust Dent J (2010) 1.45
Meta-analysis: incidence of endoscopic gastric and duodenal ulcers in placebo arms of randomized placebo-controlled NSAID trials. Aliment Pharmacol Ther (2009) 1.44
Immune thrombocytopenia in association with acute lymphoblastic leukaemia and a haemophagocytic syndrome. Eur J Haematol (1993) 1.44
Pregnancy outcomes, infant mortality, and arsenic in drinking water in West Bengal, India. Am J Epidemiol (2006) 1.43
Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2. Oncogene (2001) 1.42
MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R. Oncogene (2012) 1.42
Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester. J Immunol (1994) 1.40
Studies in Newcastle Disease: III. Production of a Hyperimmune Serum in a Horse. Can J Comp Med Vet Sci (1951) 1.39
Infectious Anaemia and Encephalomyelitis Vaccination. Can J Comp Med Vet Sci (1943) 1.39
Development of a program to manage costly outliers. Clin Nurse Spec (2001) 1.39
Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability. Am J Physiol (1999) 1.38
Persistence Of Neutralizing Antibody In Milk And Blood Of Cows And Goats Following The Instillation Of Virus Into The Mammary Gland. Can J Comp Med Vet Sci (1954) 1.37
Respiratory symptoms and skin reactivity in workers exposed to proteolytic enzymes in the detergent industry. Am Rev Respir Dis (1971) 1.36
Myxoviruses And Their Propagation In The Mammary Gland Of Ruminants. Can J Comp Med Vet Sci (1958) 1.34
Automated annotation of GPI anchor sites: case study C. elegans. Trends Biochem Sci (2000) 1.34
Impact of a standard medication chart on prescribing errors: a before-and-after audit. Qual Saf Health Care (2009) 1.33
Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network. J Biol Chem (2000) 1.31
Cyanide-insensitive, Salicylhydroxamic Acid-sensitive Processes in Potentiation of Light-requiring Lettuce Seeds. Plant Physiol (1979) 1.30
Canada's Oldest Veterinary Practice. Can J Comp Med Vet Sci (1953) 1.29
Events leading up to and the establishment of the Grosse Ile Quarantine Station. Med Serv J Can (1967) 1.28
Canada's Oldest Veterinary Practice. Can J Comp Med Vet Sci (1952) 1.27
Identification and characterization of the phosphatidylinositol-(4, 5)-bisphosphate 5-phosphatase in human platelets. J Biol Chem (1994) 1.26
A fatal thrombotic disorder associated with an acquired inhibitor of protein C. N Engl J Med (1987) 1.25
Calcium ion involvement in growth inhibition of mechanically stressed soybean (Glycine max) seedlings. Physiol Plant (1989) 1.24
Apoptosis, proliferation and p53 gene expression of H. pylori associated gastric epithelial lesions. World J Gastroenterol (2001) 1.22
Importance of the indoor environment in air pollution exposure. Arch Environ Health (1977) 1.22
Community studies of lung disease in Connecticut: organization and methods. Am J Epidemiol (1976) 1.21
Inhibition of viral gene expression by human ribonuclease P. RNA (1998) 1.20
Antibody production in goat milk serum after virus instillation of goat mammary gland. V. Biochemical isolation and further characterization of antibodies to various influenza and mumps viruses. Can J Microbiol (1970) 1.20
Regulation of endothelial monocyte-activating polypeptide II release by apoptosis. Proc Natl Acad Sci U S A (1998) 1.18
Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors. Cancer (1998) 1.18
Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase. J Biol Chem (1991) 1.16
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin. J Cell Biol (2001) 1.15
Effects of reactive oxygen species from activated leucocytes on human sperm motility, viability and morphology. Andrologia (2011) 1.15
Interaction of PKC and NOS in signal transduction of microvascular hyperpermeability. Am J Physiol (1997) 1.13
Airway disease caused by phenolic (phenol-formaldehyde) resin exposure. Arch Environ Health (1975) 1.12
Thrombomodulin, an endothelial anticoagulant protein, is absent from the human brain. Blood (1986) 1.11
Characterization of a cDNA encoding the 43-kDa membrane-associated inositol-polyphosphate 5-phosphatase. J Biol Chem (1994) 1.11
Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood (2000) 1.11
Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin alphaIIbbeta3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots. J Biol Chem (1997) 1.10
Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. J Biol Chem (2001) 1.10
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis. J Biol Chem (2000) 1.10
Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells. J Biol Chem (2000) 1.10