N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions.

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Published in J Biol Chem on July 28, 1995

Authors

R Hashimoto1, H Fujiwara, N Higashihashi, T Enjoh-Kimura, H Terasawa, Y Fujita-Yamaguchi, F Inagaki, J F Perdue, K Sakano

Author Affiliations

1: Molecular Biology Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan.

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