Published in J Exp Med on September 01, 1995
Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68
Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood (2005) 3.99
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J Exp Med (1998) 3.83
Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol (2012) 3.43
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J Exp Med (1998) 3.09
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood (2009) 2.75
p46, a novel natural killer cell-specific surface molecule that mediates cell activation. J Exp Med (1997) 2.70
Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc Natl Acad Sci U S A (2005) 2.55
Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity. J Clin Invest (2011) 2.44
Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis. J Exp Med (2001) 2.41
Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors. Proc Natl Acad Sci U S A (1998) 1.79
Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe (2010) 1.74
A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction. J Exp Med (1997) 1.59
Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J Exp Med (1996) 1.42
Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc Natl Acad Sci U S A (1996) 1.39
Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene. J Exp Med (1997) 1.38
Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin Exp Immunol (2007) 1.38
Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J Exp Med (1997) 1.37
NKG2A complexed with CD94 defines a novel inhibitory natural killer cell receptor. J Exp Med (1997) 1.35
Natural killer cells and cancer: regulation by the killer cell Ig-like receptors (KIR). Cancer Biol Ther (2009) 1.32
Self and viral peptides can initiate lysis by autologous natural killer cells. Proc Natl Acad Sci U S A (1997) 1.29
Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity. J Exp Med (1999) 1.27
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones. Proc Natl Acad Sci U S A (1996) 1.23
Putting the natural killer cell in its place. Immunology (2006) 1.20
Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity. J Exp Med (1997) 1.18
The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT). Immunol Rev (2014) 1.16
Dendritic cell interactions with NK cells from different tissues. J Clin Immunol (2009) 1.12
An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes. J Exp Med (1996) 1.11
Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells. Front Immunol (2013) 1.10
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. J Exp Med (1999) 1.08
Clinical utility of natural killer cells in cancer therapy and transplantation. Semin Immunol (2014) 1.07
TLR/NCR/KIR: Which One to Use and When? Front Immunol (2014) 1.03
The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins. Proc Natl Acad Sci U S A (2001) 1.02
Discrimination between the main activating and inhibitory killer cell immunoglobulin-like receptor positive natural killer cell subsets using newly characterized monoclonal antibodies. Immunology (2009) 1.01
Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes. J Exp Med (2001) 0.98
Reciprocal age related change in natural killer cell receptors for MHC class I. Mech Ageing Dev (2005) 0.97
Natural killer activating receptors trigger interferon gamma secretion from T cells and natural killer cells. Proc Natl Acad Sci U S A (1998) 0.97
Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development. J Exp Med (1997) 0.96
A comprehensive analysis of the binding of anti-KIR antibodies to activating KIRs. Genes Immun (2013) 0.95
Activating killer cell Ig-like receptors in health and disease. Front Immunol (2014) 0.95
Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. J Exp Med (2001) 0.94
Nature of allelic sequence polymorphism at the KIR3DL3 locus. Immunogenetics (2006) 0.92
Biology and clinical effects of natural killer cells in allogeneic transplantation. Curr Opin Oncol (2010) 0.92
The transmembrane sequence of human histocompatibility leukocyte antigen (HLA)-C as a determinant in inhibition of a subset of natural killer cells. J Exp Med (1999) 0.92
Natural killer cell mediated missing-self recognition can protect mice from primary chronic myeloid leukemia in vivo. PLoS One (2011) 0.91
Association of activating KIR copy number variation of NK cells with containment of SIV replication in rhesus monkeys. PLoS Pathog (2011) 0.91
Impact of HCMV Infection on NK Cell Development and Function after HSCT. Front Immunol (2013) 0.90
Differential impact of inhibitory and activating Killer Ig-Like Receptors (KIR) on high-risk patients with myeloid and lymphoid malignancies undergoing reduced intensity transplantation from haploidentical related donors. Bone Marrow Transplant (2011) 0.89
Distribution of killer cell immunoglobulin-like receptors genes in the Italian Caucasian population. J Transl Med (2006) 0.88
Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors. Clin Exp Immunol (2000) 0.88
Activating and inhibitory killer immunoglobulin-like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high-risk leukaemias. Clin Exp Immunol (2009) 0.88
Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population. Croat Med J (2007) 0.88
Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87
The lectin-like receptor KLRE1 inhibits natural killer cell cytotoxicity. J Exp Med (2003) 0.86
On the cell biology of pit cells, the liver-specific NK cells. World J Gastroenterol (2000) 0.86
Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer. Oncotarget (2015) 0.85
Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory? Front Immunol (2015) 0.83
Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation. Semin Immunopathol (2008) 0.82
Cell mediators of autoimmune hepatitis and their therapeutic implications. Dig Dis Sci (2014) 0.82
An improved RT-PCR method for the detection of killer-cell immunoglobulin-like receptor (KIR) transcripts. Immunogenetics (2006) 0.81
The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins. Viruses (2011) 0.81
Modulation of Human Leukocyte Antigen-C by Human Cytomegalovirus Stimulates KIR2DS1 Recognition by Natural Killer Cells. Front Immunol (2017) 0.80
Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3. PLoS Negl Trop Dis (2014) 0.80
Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles. J Immunol Res (2015) 0.79
Preferential interaction of a novel tumor surface protein (p38.5) with naive natural killer cells. J Exp Med (1997) 0.79
Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies. Haematologica (2015) 0.79
The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling. Cell Rep (2016) 0.79
Deciphering the KIR system at super-resolution for NK and T cell biology. Immunology (2016) 0.79
Differential expression of cytotoxic molecules and killer cell inhibitory receptors in CD8+ and CD56+ cutaneous lymphomas. Am J Pathol (2001) 0.78
The role of NK cells in HIV-1 protection: autologous, allogeneic or both? AIDS Res Ther (2016) 0.77
The early days of NK cells: an example of how a phenomenon led to detection of a novel immune receptor system - lessons from a rat model. Front Immunol (2014) 0.77
Natural Killer Cells for Therapy of Leukemia. Transfus Med Hemother (2016) 0.76
The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands. Immunogenetics (2014) 0.76
Ligand specificity of Killer cell Immunoglobulin-like Receptors: a brief history of KIR. Front Immunol (2012) 0.76
Features of Memory-Like and PD-1(+) Human NK Cell Subsets. Front Immunol (2016) 0.76
Genotypic diversity of the Killer Cell Immunoglobulin-like Receptors (KIR) and their HLA class I Ligands in a Saudi population. Genet Mol Biol (2016) 0.76
KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans. Immun Inflamm Dis (2017) 0.75
Human Leukocyte Antigen-C Genotype and Killer Immunoglobulin-like Receptor-Ligand Matching in Korean Living Donor Liver Transplantation. Ann Lab Med (2017) 0.75
Detection of monoclonal T populations in patients with KIR-restricted chronic lymphoproliferative disorder of NK cells. Haematologica (2014) 0.75
Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing. Oncoimmunology (2015) 0.75
KIR3DS1-Mediated Recognition of HLA-*B51: Modulation of KIR3DS1 Responsiveness by Self HLA-B Allotypes and Effect on NK Cell Licensing. Front Immunol (2017) 0.75
The impact of KIR-HLA genotype on hepatitis B virus clearance in Iranian infected individuals. Med Microbiol Immunol (2017) 0.75
MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma. Oncoimmunology (2017) 0.75
A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20
In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today (1990) 10.84
MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature (1992) 5.04
Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity. J Exp Med (1983) 4.47
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity (1995) 3.72
Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line. J Immunol (1989) 3.24
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med (1990) 2.93
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med (1994) 2.59
Allorecognition by NK cells: nonself or no self? Immunol Today (1992) 2.21
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. J Exp Med (1992) 2.04
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med (1994) 1.98
Human natural killer cells: origin, clonality, specificity, and receptors. Adv Immunol (1994) 1.83
A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate. Eur J Immunol (1991) 1.32
To thine own self be true... Curr Biol (1991) 1.29
Recognition of major histocompatibility complex class I antigens by natural killer cells. J Exp Med (1994) 1.23
The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 zeta chain, Fc epsilon RI gamma chain and the p56lck kinase. Eur J Immunol (1994) 1.18
Immunology. A sense of something missing. Nature (1992) 1.13
CD45-mediated regulation of LFA1 function in human natural killer cells. Anti-CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules. Eur J Immunol (1993) 1.06
An unexpected petition for pardon. Curr Biol (1992) 1.02
Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG. J Exp Med (1977) 9.57
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol (2001) 7.07
Classification of European mtDNAs from an analysis of three European populations. Genetics (1996) 6.28
Expression of a receptor for IgM by human T cells in vitro. Eur J Immunol (1975) 5.05
Subpopulations of human T cells identified by receptors for immunoglobulins and mitogen responsiveness. J Immunol (1976) 4.64
Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity. J Exp Med (1983) 4.47
Receptors for HLA class-I molecules in human natural killer cells. Annu Rev Immunol (1996) 4.24
Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy. Nat Med (1998) 4.17
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J Exp Med (1998) 3.83
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity (1995) 3.72
Receptors for IgG molecules on human lymphocytes forming spontaneous rosettes with sheep red cells. Eur J Immunol (1975) 3.26
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J Exp Med (1998) 3.09
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. J Exp Med (1999) 3.08
Human T lymphocyte subpopulations defined by Fc receptors and monoclonal antibodies. A comparison. J Exp Med (1980) 3.03
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med (1990) 2.93
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor. J Exp Med (1988) 2.86
Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. Immunity (1997) 2.71
p46, a novel natural killer cell-specific surface molecule that mediates cell activation. J Exp Med (1997) 2.70
bcl-2 expression in pleural and extrapleural solitary fibrous tumours. J Pathol (1997) 2.66
Morphological and histochemical analyses of two human T-cell subpopulations bearing receptors for IgM or IgG. J Exp Med (1978) 2.58
Fc-receptor heterogeneity of human suppressor T cells. J Immunol (1978) 2.37
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. J Exp Med (1999) 2.17
Quantitative assessment of the pool size and subset distribution of cytolytic T lymphocytes within human resting or alloactivated peripheral blood T cell populations. J Exp Med (1983) 2.16
Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture. J Exp Med (1988) 2.14
Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci U S A (1992) 2.08
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. J Exp Med (1992) 2.04
Demonstration of safety of probiotics -- a review. Int J Food Microbiol (1998) 2.02
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med (1994) 1.98
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis. Immunol Today (2000) 1.95
Human natural killer cell receptors and co-receptors. Immunol Rev (2001) 1.94
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. Eur J Immunol (2001) 1.93
Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells. J Immunol (1997) 1.92
Thrombosis in the portal venous system after elective laparoscopic splenectomy. Surg Endosc (2004) 1.92
Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex. J Exp Med (1985) 1.92
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J Immunol (1996) 1.90
Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tract. J Appl Microbiol (1998) 1.90