Published in J Cell Biol on January 01, 1993
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Mol Biol Cell (2000) 2.73
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J (2002) 2.70
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J (2004) 1.71
The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity. J Neurosci Res (2009) 1.65
Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro. J Cell Biol (1995) 1.58
1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C. Proc Natl Acad Sci U S A (2007) 1.51
UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. Genes Dev (2008) 1.40
Release of kinesin from vesicles by hsc70 and regulation of fast axonal transport. Mol Biol Cell (2000) 1.39
Spatiotemporal regulation of ATP and Ca2+ dynamics in vertebrate rod and cone ribbon synapses. Mol Vis (2007) 1.18
A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins. J Cell Biol (1995) 1.11
Mitochondria and neurotransmission: evacuating the synapse. Neuron (2005) 1.10
In vitro reconstitution of microtubule plus end-directed, GTPgammaS-sensitive motility of Golgi membranes. Mol Biol Cell (1998) 0.98
Mitochondrial configurations in peripheral nerve suggest differential ATP production. J Struct Biol (2010) 0.91
G proteins: transducers of receptor-generated signals. Annu Rev Biochem (1987) 27.41
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell (1985) 13.73
The GTPase superfamily: a conserved switch for diverse cell functions. Nature (1990) 11.71
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell (1990) 9.60
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem J (1988) 8.02
Molecular dissection of the secretory pathway. Nature (1992) 7.38
Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic. Nature (1991) 6.29
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett (1990) 6.20
A novel brain ATPase with properties expected for the fast axonal transport motor. Nature (1985) 5.30
The cellular functions of small GTP-binding proteins. Science (1990) 5.16
Retrograde transport by the microtubule-associated protein MAP 1C. Nature (1987) 5.06
ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell (1991) 4.80
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature (1991) 4.69
Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell (1985) 4.61
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature (1990) 4.30
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature (1989) 4.27
ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc Natl Acad Sci U S A (1990) 4.12
Cytoplasmic dynein is a minus end-directed motor for membranous organelles. Cell (1989) 4.05
Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride. Proc Natl Acad Sci U S A (1982) 3.73
A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell (1990) 3.65
Single microtubules from squid axoplasm support bidirectional movement of organelles. Cell (1985) 3.55
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J Biol Chem (1986) 3.49
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun (1987) 3.46
Dynein is the motor for retrograde axonal transport of organelles. Proc Natl Acad Sci U S A (1989) 3.45
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein. Science (1991) 3.33
Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. J Cell Biol (1991) 3.22
Fast axonal transport in extruded axoplasm from squid giant axon. Science (1982) 3.19
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles. Proc Natl Acad Sci U S A (1990) 3.13
An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues. FEBS Lett (1989) 3.10
The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles. J Cell Biol (1980) 3.08
Radial extension of macrophage tubular lysosomes supported by kinesin. Nature (1990) 2.96
Fast axonal transport in squid giant axon. Science (1982) 2.96
A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proc Natl Acad Sci U S A (1990) 2.89
Casein kinases--multipotential protein kinases. Curr Top Cell Regul (1982) 2.85
Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans. Cell (1987) 2.81
Bovine brain kinesin is a microtubule-activated ATPase. Proc Natl Acad Sci U S A (1986) 2.80
Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo. J Cell Biol (1990) 2.76
Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature (1992) 2.45
Polarity of axoplasmic microtubules in the olfactory nerve of the frog. Proc Natl Acad Sci U S A (1981) 2.39
Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol (1989) 2.38
Kinesin associates with anterogradely transported membranous organelles in vivo. J Cell Biol (1991) 2.32
A small GTP-binding protein dissociates from synaptic vesicles during exocytosis. Nature (1991) 2.29
Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins. J Biol Chem (1991) 2.20
Small GTP-binding proteins and their role in transport. Curr Opin Cell Biol (1991) 2.19
Adenosine 5'-O(3-thiotriphosphate) in the control of phosphorylase activity. Biochem Biophys Res Commun (1974) 1.99
Specific binding of [alpha-32P]GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C. Proc Natl Acad Sci U S A (1987) 1.99
Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP. Nature (1985) 1.96
Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms. Cell Motil (1985) 1.95
Characterization of the microtubule movement produced by sea urchin egg kinesin. J Biol Chem (1987) 1.92
Association of Rab3A with synaptic vesicles at late stages of the secretory pathway. J Cell Biol (1991) 1.91
The short term accumulation of axonally transported organelles in the region of localized lesions of single myelinated axons. J Neurocytol (1980) 1.88
Chemical and immunological characterization of the 21-kDa ADP-ribosylation factor of adenylate cyclase. J Biol Chem (1988) 1.80
Stable polymers of the axonal cytoskeleton: the axoplasmic ghost. J Cell Biol (1982) 1.74
Immunolocalization of cytoplasmic dynein to lysosomes in cultured cells. J Cell Sci (1992) 1.72
Irreversible thiophosphorylation and activation of tension in functionally skinned rabbit ileum strips by [35S]ATP gamma S. J Biol Chem (1979) 1.63
Bidirectional pigment granule movements of melanophores are regulated by protein phosphorylation and dephosphorylation. Cell (1986) 1.55
Binding and hydrolysis of guanine nucleotides by Sec4p, a yeast protein involved in the regulation of vesicular traffic. J Biol Chem (1990) 1.54
Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C). J Cell Biol (1988) 1.51
Okadaic acid induces Golgi apparatus fragmentation and arrest of intracellular transport. J Cell Sci (1991) 1.48
Evidence for the regulation of exocytic transport by protein phosphorylation. J Cell Biol (1992) 1.48
A dynamin-like protein encoded by the yeast sporulation gene SPO15. Nature (1991) 1.45
Action of brefeldin A blocked by activation of a pertussis-toxin-sensitive G protein. Nature (1992) 1.44
Intracellular cyclic AMP not calcium, determines the direction of vesicle movement in melanophores: direct measurement by fluorescence ratio imaging. J Cell Biol (1992) 1.37
Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites. Cell Motil (1984) 1.30
Regulation of organelle transport in melanophores by calcineurin. J Cell Biol (1990) 1.23
Trimeric G-proteins of the trans-Golgi network are involved in the formation of constitutive secretory vesicles and immature secretory granules. FEBS Lett (1991) 1.22
Mechanisms of muscarinic receptor action on Go in reconstituted phospholipid vesicles. J Biol Chem (1989) 1.21
Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin. J Cell Biol (1991) 1.19
Copurification of kinesin polypeptides with microtubule-stimulated Mg-ATPase activity and kinetic analysis of enzymatic properties. Cell Motil Cytoskeleton (1989) 1.18
Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm. J Neurosci (1989) 1.17
Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a. J Cell Biol (1991) 1.13
Reactivated melanophore motility: differential regulation and nucleotide requirements of bidirectional pigment granule transport. J Cell Biol (1986) 1.12
Nucleotide specificity for the bidirectional transport of membrane-bounded organelles in isolated axoplasm. Cell Motil Cytoskeleton (1990) 1.04
Regulation of pigment organelle translocation. II. Participation of a cAMP-dependent protein kinase. J Biol Chem (1986) 0.99
Regulation of pigment organelle translocation. I. Phosphorylation of the organelle-associated protein p57. J Biol Chem (1986) 0.99
K-252a, a potent protein kinase inhibitor, blocks nerve growth factor-induced neurite outgrowth and changes in the phosphorylation of proteins in PC12h cells. J Cell Biol (1988) 0.97
Principal neurofilament-associated protein kinase in squid axoplasm is related to casein kinase I. J Biol Chem (1991) 0.95
Identification and quantification of calcium-binding proteins in squid axoplasm. J Neurosci (1988) 0.94
AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axons. J Neurocytol (1985) 0.93
Polarity orientations of microtubules in squid and lobster axons. J Neurocytol (1987) 0.85
Inhibition by K-252a, a new inhibitor of protein kinase, of nerve growth factor-induced neurite outgrowth of chick embryo dorsal root ganglion cells. Neurosci Lett (1988) 0.80
Pertussis toxin-sensitive G proteins are transported toward synaptic terminals by fast axonal transport. Proc Natl Acad Sci U S A (1991) 0.78
A novel brain ATPase with properties expected for the fast axonal transport motor. Nature (1985) 5.30
Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell (1989) 4.12
Direct interaction of microtubule- and actin-based transport motors. Nature (1999) 3.25
Fast axonal transport in extruded axoplasm from squid giant axon. Science (1982) 3.19
Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry (1988) 3.17
Fast axonal transport in squid giant axon. Science (1982) 2.96
Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell (1992) 2.80
Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol (1989) 2.38
Kinesin associates with anterogradely transported membranous organelles in vivo. J Cell Biol (1991) 2.32
Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis. J Clin Invest (1997) 2.30
Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol (1995) 2.02
Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog. J Clin Invest (1999) 2.02
Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP. Nature (1985) 1.96
Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms. Cell Motil (1985) 1.95
Strategic planning of acute beds by specialty. Br Med J (1979) 1.83
Axonal transport of the cytoplasmic matrix. J Cell Biol (1984) 1.78
Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport. J Neurosci (2000) 1.73
Sphingomyelinase treatment induces ATP-independent endocytosis. J Cell Biol (1998) 1.72
Immunochemical analysis of kinesin light chain function. Mol Biol Cell (1997) 1.72
X-ray structure of motor and neck domains from rat brain kinesin. Biochemistry (1997) 1.71
Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein. J Virol (2001) 1.70
Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors. J Virol (1999) 1.59
Association of kinesin with characterized membrane-bounded organelles. Cell Motil Cytoskeleton (1992) 1.59
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus. J Clin Invest (1999) 1.56
CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts. J Clin Invest (1999) 1.55
Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc Natl Acad Sci U S A (1991) 1.54
Axonal tubulin and axonal microtubules: biochemical evidence for cold stability. J Cell Biol (1984) 1.52
1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C. Proc Natl Acad Sci U S A (2007) 1.51
Blood pressure in Down's syndrome. J Ment Defic Res (1979) 1.46
Observations on mosaic parents of mongol propositi. J Ment Defic Res (1970) 1.44
Release of kinesin from vesicles by hsc70 and regulation of fast axonal transport. Mol Biol Cell (2000) 1.39
Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments. Nature (1984) 1.37
Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Mol Biol Cell (1995) 1.35
Nerve-specific enolase and creatine phosphokinase in axonal transport: soluble proteins and the axoplasmic matrix. Cell (1981) 1.35
Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites. Cell Motil (1984) 1.30
Axonal transport of a subclass of tau proteins: evidence for the regional differentiation of microtubules in neurons. Proc Natl Acad Sci U S A (1984) 1.25
Purification of kinesin from bovine brain and assay of microtubule-stimulated ATPase activity. Methods Enzymol (1991) 1.21
Mortality trends in mental deficiency institutions. J Ment Defic Res (1969) 1.21
Fragile X-linked mental retardation: the Martin-Bell syndrome. J Ment Defic Res (1981) 1.20
Copurification of kinesin polypeptides with microtubule-stimulated Mg-ATPase activity and kinetic analysis of enzymatic properties. Cell Motil Cytoskeleton (1989) 1.18
Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm. J Neurosci (1989) 1.17
Investigation of 142 mosaic mongols and mosaic parents of mongols; cytogenetic analysis and maternal age at birth. J Ment Defic Res (1974) 1.15
Axonal transport: a cell-biological method for studying proteins that associate with the cytoskeleton. Methods Cell Biol (1982) 1.13
The recurrence of monogolism in sibships. J Ment Defic Res (1977) 1.09
A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. J Neurosci (1998) 1.06
Regulation of kinesin: implications for neuronal development. Dev Neurosci (2001) 1.04
Nucleotide specificity for the bidirectional transport of membrane-bounded organelles in isolated axoplasm. Cell Motil Cytoskeleton (1990) 1.04
The axon: a prototype for studying expressional cytoplasm. Cold Spring Harb Symp Quant Biol (1982) 1.02
Changes in microtubule stability and density in myelin-deficient shiverer mouse CNS axons. J Neurosci (2001) 1.01
Plasminogen activator system in human coronary atherosclerosis. Arterioscler Thromb Vasc Biol (1995) 1.01
The incidence of mongol twins. J Ment Defic Res (1971) 1.01
Assay of vesicle motility in squid axoplasm. Methods Cell Biol (1993) 1.01
AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL. Gene Ther (2005) 1.01
Diversity in the axonal transport of structural proteins: major differences between optic and spinal axons in the rat. J Neurosci (1986) 1.00
Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor. Am J Respir Cell Mol Biol (1999) 0.99
Axonal tubulin and microtubules: morphologic evidence for stable regions on axonal microtubules. Cell Motil Cytoskeleton (1987) 0.99
Fast axonal transport of foreign synaptic vesicles in squid axoplasm. J Cell Biol (1985) 0.98
Modulation of the axonal microtubule cytoskeleton by myelinating Schwann cells. J Neurosci (1994) 0.98
Cytotypic differences in the protein composition of the axonally transported cytoskeleton in mammalian neurons. J Neurosci (1987) 0.97
Axonal transport of calmodulin: a physiologic approach to identification of long-term associations between proteins. J Cell Biol (1981) 0.97
Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport. Biochemistry (1989) 0.97
Mosaic mongolism. J Ment Defic Res (1969) 0.97
Fast axonal transport in the presence of high Ca2+: evidence that microtubules are not required. Proc Natl Acad Sci U S A (1980) 0.96
Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract. Hum Gene Ther (1997) 0.95
Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle. Mol Ther (2001) 0.95
AVEC-DIC and electron microscopic analyses of axonally transported particles in cold-blocked squid giant axons. J Neurocytol (1985) 0.93
Molecular motors in axonal transport. Cellular and molecular biology of kinesin. Mol Neurobiol (1993) 0.92
Altered slow axonal transport and regeneration in a myelin-deficient mutant mouse: the trembler as an in vivo model for Schwann cell-axon interactions. J Neurosci (1990) 0.92
Intravascular ultrasonographic assessment of the results of coronary artery stenting. Am Heart J (1993) 0.92
G-group ring chromosome in a mentally subnormal girl. J Ment Defic Res (1971) 0.92
Axonal transport of a clathrin uncoating ATPase (HSC70): a role for HSC70 in the modulation of coated vesicle assembly in vivo. J Neurosci Res (1989) 0.91
Pathological observations on a male patient with D-ring chromosome. J Ment Defic Res (1971) 0.91
Recurrent syphilitic uveitis. N Engl J Med (1989) 0.91
Cellular immune responses of healthy individuals to intradermal administration of an E1-E3- adenovirus gene transfer vector. Hum Gene Ther (1999) 0.90
Retardation in the slow axonal transport of cytoskeletal elements during maturation and aging. Neurobiol Aging (1989) 0.90
Unwrapping new layers of complexity in axon/glial relationships. Glia (2000) 0.89
The axonal transport motor 'kinesin' is bound to anterogradely transported organelles: quantitative cytofluorimetric studies of fast axonal transport in the rat. Acta Physiol Scand (1991) 0.89
Effect of adenovirus-mediated expression of Sonic hedgehog gene on hair regrowth in mice with chemotherapy-induced alopecia. J Natl Cancer Inst (2001) 0.88
ATP-dependent directional movement of rat synaptic vesicles injected into the presynaptic terminal of squid giant synapse. Proc Natl Acad Sci U S A (1989) 0.88
The syndrome of Coffin, Siris and Wegienka: report of a case. J Ment Defic Res (1976) 0.86
Neurofilaments run sprints not marathons. Nat Cell Biol (2000) 0.86
A case of proximal 14 trisomy with pathological findings. J Ment Defic Res (1981) 0.86
Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA. Blood (1999) 0.86
Specific binding of the adenovirus capsid to the nuclear envelope. Hum Gene Ther (1999) 0.85
IgA and ring-18 chromosome. Lancet (1968) 0.84
Studies on the pathogenesis of vincristine-induced neuropathy. Muscle Nerve (1987) 0.84
Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells. Mol Ther (2000) 0.84
Approaches to study interactions between kinesin motors and membranes. Methods Mol Biol (2001) 0.83
Axonal transport of microtubule proteins: cytotypic variation of tubulin and MAPs in neurons. Ann N Y Acad Sci (1986) 0.83
Mongolism: the effect of trends in age at childbirth on incidence and chromosomal type. J Ment Subnorm (1967) 0.83
Crystallization and preliminary X-ray analysis of the single-headed and double-headed motor protein kinesin. J Struct Biol (1997) 0.81
"Renpenning" syndrome. Lancet (1970) 0.81
Cytoplasmic dynein conversion at a crush injury in rat peripheral axons. J Neurosci Res (2000) 0.80
Purification and characterization of rat hippocampal CA3-dendritic spines associated with mossy fiber terminals. FEBS Lett (1999) 0.80
Direct effect of the neurotoxicant acrylamide on kinesin-based microtubule motility. J Neurosci Res (1996) 0.79
A unique tubulin antibody which disrupts particle movement in squid axoplasm. Cell Motil Cytoskeleton (1987) 0.79