Published in Proc Natl Acad Sci U S A on February 01, 1990
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J Cell Biol (1995) 4.78
Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. Mol Biol Cell (2006) 3.96
Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol Biol Cell (1999) 3.28
Dynactin is required for bidirectional organelle transport. J Cell Biol (2003) 3.04
KIF3A is a new microtubule-based anterograde motor in the nerve axon. J Cell Biol (1994) 2.86
Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Mol Biol Cell (2000) 2.73
Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. J Cell Biol (1992) 2.72
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J (2002) 2.70
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci (2010) 2.55
Kinesin associates with anterogradely transported membranous organelles in vivo. J Cell Biol (1991) 2.32
Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic. J Cell Biol (1995) 2.27
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc Natl Acad Sci U S A (1997) 2.26
Kinesin- and myosin-driven steps of vesicle recruitment for Ca2+-regulated exocytosis. J Cell Biol (1997) 2.23
Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J (2008) 2.03
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nat Neurosci (2009) 1.95
Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. J Cell Biol (1992) 1.91
Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm. J Cell Biol (1991) 1.89
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
Kinesin is responsible for centrifugal movement of pigment granules in melanophores. Proc Natl Acad Sci U S A (1991) 1.79
Dynein and the actin cytoskeleton control kinesin-driven cytoplasmic streaming in Drosophila oocytes. Development (2005) 1.79
Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. Mol Biol Cell (2002) 1.74
Immunochemical analysis of kinesin light chain function. Mol Biol Cell (1997) 1.72
A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J (2004) 1.71
Effects of kinesin mutations on neuronal functions. Science (1992) 1.69
Kinesin-mediated organelle translocation revealed by specific cellular manipulations. J Cell Biol (1994) 1.65
Kinesin superfamily protein 3 (KIF3) motor transports fodrin-associating vesicles important for neurite building. J Cell Biol (2000) 1.60
Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport. J Neurosci (2009) 1.57
Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proc Natl Acad Sci U S A (1991) 1.54
1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C. Proc Natl Acad Sci U S A (2007) 1.51
Evidence for myosin motors on organelles in squid axoplasm. Proc Natl Acad Sci U S A (1993) 1.49
The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties. Mol Biol Cell (1995) 1.47
Kinesin is essential for cell morphogenesis and polarized secretion in Neurospora crassa. EMBO J (1997) 1.46
Host cell invasion by trypanosomes requires lysosomes and microtubule/kinesin-mediated transport. J Cell Biol (1996) 1.45
Modulation of substrate adhesion dynamics via microtubule targeting requires kinesin-1. J Cell Biol (2002) 1.42
Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments. Mol Biol Cell (2009) 1.41
Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro. Proc Natl Acad Sci U S A (1991) 1.40
Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. J Neurosci (2007) 1.39
Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules. J Cell Biol (1992) 1.36
Cytoplasmic dynein mediates adenovirus binding to microtubules. J Virol (2004) 1.36
Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Mol Biol Cell (1995) 1.35
Microtubule-based endoplasmic reticulum motility in Xenopus laevis: activation of membrane-associated kinesin during development. Mol Biol Cell (1999) 1.28
Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res (2012) 1.26
Cargo selection by specific kinesin light chain 1 isoforms. EMBO J (2006) 1.21
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport. J Cell Biol (2011) 1.19
Tau oligomers and tau toxicity in neurodegenerative disease. Biochem Soc Trans (2012) 1.18
Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy. Neurotoxicology (2013) 1.18
Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila. J Cell Biol (2010) 1.17
Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton. BMC Evol Biol (2010) 1.17
Golgi positioning. Cold Spring Harb Perspect Biol (2011) 1.17
Retrograde axonal transport and motor neuron disease. J Neurochem (2008) 1.17
Nucleotide specificities of anterograde and retrograde organelle transport in Reticulomyxa are indistinguishable. J Cell Biol (1991) 1.14
Clonal tests of conventional kinesin function during cell proliferation and differentiation. Mol Biol Cell (2000) 1.11
Single kinesin molecules crossbridge microtubules in vitro. Proc Natl Acad Sci U S A (1993) 1.09
GTP gamma S inhibits organelle transport along axonal microtubules. J Cell Biol (1993) 1.07
Axonal transport deficit in a KIF5A( -/- ) mouse model. Neurogenetics (2012) 1.06
Synaptic activation modifies microtubules underlying transport of postsynaptic cargo. Proc Natl Acad Sci U S A (2009) 1.06
Pollen semi-sterility1 encodes a kinesin-1-like protein important for male meiosis, anther dehiscence, and fertility in rice. Plant Cell (2011) 1.05
Kinectin is a key effector of RhoG microtubule-dependent cellular activity. Mol Cell Biol (2001) 1.01
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell (2012) 1.00
Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver. Mol Biol Cell (2007) 0.99
RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system. EMBO Rep (2009) 0.99
In vitro reconstitution of microtubule plus end-directed, GTPgammaS-sensitive motility of Golgi membranes. Mol Biol Cell (1998) 0.98
Role of MAP1B in axonal retrograde transport of mitochondria. Biochem J (2006) 0.97
Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export. PLoS Pathog (2010) 0.97
Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm. Proc Natl Acad Sci U S A (2013) 0.94
Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A (2012) 0.90
In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors. J Biol Chem (2011) 0.90
Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma. Front Neurosci (2014) 0.88
Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. FASEB J (2009) 0.88
Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming. Development (2011) 0.86
The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway. Oncogene (2012) 0.83
Analyses of dynein heavy chain mutations reveal complex interactions between dynein motor domains and cellular dynein functions. Genetics (2012) 0.82
Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2. Open Biol (2013) 0.82
Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling. PLoS Genet (2013) 0.81
Building Blocks of Functioning Brain: Cytoskeletal Dynamics in Neuronal Development. Int Rev Cell Mol Biol (2016) 0.80
Unconventional functions of microtubule motors. Arch Biochem Biophys (2012) 0.79
Quantitative measurements and modeling of cargo-motor interactions during fast transport in the living axon. Phys Biol (2012) 0.78
Live cell imaging reveals differential modifications to cytoplasmic dynein properties by phospho- and dephosphomimic mutations of the intermediate chain 2C S84. J Neurosci Res (2014) 0.77
No conventional function for the conventional kinesin? Traffic (2008) 0.76
Spatial and temporal characteristics of normal and perturbed vesicle transport. PLoS One (2014) 0.75
HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways. ASN Neuro (2016) 0.75
Neurofilament Light as an Immune Target for Pathogenic Antibodies. Immunology (2017) 0.75
Enhanced Dynamics of Confined Cytoskeletal Filaments Driven by Asymmetric Motors. Biophys J (2017) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell (1985) 13.73
A simple method of reducing the fading of immunofluorescence during microscopy. J Immunol Methods (1981) 10.77
A novel brain ATPase with properties expected for the fast axonal transport motor. Nature (1985) 5.30
Retrograde transport by the microtubule-associated protein MAP 1C. Nature (1987) 5.06
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell (1985) 4.61
Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell (1989) 4.12
The effect of myosin antibody on the division of starfish blastomeres. J Cell Biol (1977) 3.92
Intracellular transport using microtubule-based motors. Annu Rev Cell Biol (1987) 3.84
Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle. Nature (1986) 3.44
Fast axonal transport in extruded axoplasm from squid giant axon. Science (1982) 3.19
Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry (1988) 3.17
Identification of globular mechanochemical heads of kinesin. Nature (1989) 2.83
Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans. Cell (1987) 2.81
Bovine brain kinesin is a microtubule-activated ATPase. Proc Natl Acad Sci U S A (1986) 2.80
Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains. J Cell Biol (1988) 2.69
Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol (1989) 2.38
Cross-bridges mediate anterograde and retrograde vesicle transport along microtubules in squid axoplasm. J Cell Biol (1985) 2.32
Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP. Nature (1985) 1.96
Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms. Cell Motil (1985) 1.95
Characterization of the microtubule movement produced by sea urchin egg kinesin. J Biol Chem (1987) 1.92
Evidence that myosin does not contribute to force production in chromosome movement. J Cell Biol (1982) 1.75
An ATPase with properties expected for the organelle motor of the giant amoeba, Reticulomyxa. Nature (1988) 1.73
Kinesin is associated with a nonmicrotubule component of sea urchin mitotic spindles. Proc Natl Acad Sci U S A (1987) 1.67
Localization of kinesin in cultured cells. J Cell Biol (1988) 1.58
Modulation of cellular morphology and locomotory activity by antibodies against myosin. J Cell Biol (1988) 1.45
Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments. Nature (1984) 1.37
Monomer-polymer equilibria in the axon: direct measurement of tubulin and actin as polymer and monomer in axoplasm. J Cell Biol (1984) 1.36
Copurification of kinesin polypeptides with microtubule-stimulated Mg-ATPase activity and kinetic analysis of enzymatic properties. Cell Motil Cytoskeleton (1989) 1.18
Microinjection into Acanthamoeba castellanii of monoclonal antibodies to myosin-II slows but does not stop cell locomotion. Cell Motil Cytoskeleton (1989) 1.14
Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport. Biochemistry (1989) 0.97
Purification and characterization of kinesin from bovine adrenal medulla. J Biol Chem (1988) 0.95
Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell (1989) 4.12
Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. J Cell Biol (1990) 3.90
Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry (1988) 3.17
Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature (1991) 2.99
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem (1993) 2.91
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Purification and polypeptide composition of dynein ATPases from Chlamydomonas flagella. Cell Motil (1982) 2.79
Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol (1984) 2.38
Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. J Cell Biol (1989) 2.38
Kinesin associates with anterogradely transported membranous organelles in vivo. J Cell Biol (1991) 2.32
Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic. J Cell Biol (1995) 2.27
Brain cytoplasmic and flagellar outer arm dyneins share a highly conserved Mr 8,000 light chain. J Biol Chem (1996) 2.20
Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles. J Cell Biol (1994) 2.14
Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. J Cell Biol (1984) 2.03
A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. J Cell Biol (1995) 2.02
Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther (2000) 1.97
Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A. Neuron (1996) 1.93
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Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. J Cell Biol (1992) 1.81
IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments. J Cell Biol (1997) 1.78
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Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton. Proc Natl Acad Sci U S A (1985) 1.72
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Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps. J Cell Biol (1995) 1.67
Association of kinesin with characterized membrane-bounded organelles. Cell Motil Cytoskeleton (1992) 1.59
Isolation of sea urchin egg microtubules with taxol and identification of mitotic spindle microtubule-associated proteins with monoclonal antibodies. Proc Natl Acad Sci U S A (1983) 1.55
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The mouse t-complex-encoded protein Tctex-1 is a light chain of brain cytoplasmic dynein. J Biol Chem (1996) 1.54
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Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport. J Neurosci (1996) 1.23
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Purification of kinesin from bovine brain and assay of microtubule-stimulated ATPase activity. Methods Enzymol (1991) 1.21
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Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport. Biochemistry (1989) 0.97
Labeling of Chlamydomonas 18 S dynein polypeptides by 8-azidoadenosine 5'-triphosphate, a photoaffinity analog of ATP. J Biol Chem (1985) 0.95
Identification of high molecular weight microtubule-associated proteins in anterior pituitary tissue and cells using taxol-dependent purification combined with microtubule-associated protein specific antibodies. Biochemistry (1985) 0.93
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