Published in Nature on September 20, 1990
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol (1994) 11.55
Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol (1993) 7.37
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol (1999) 5.53
Dynamin-mediated internalization of caveolae. J Cell Biol (1998) 5.26
end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae. J Cell Biol (1993) 5.22
Effects of mutant rat dynamin on endocytosis. J Cell Biol (1993) 5.05
Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol (1999) 4.70
Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium. J Cell Biol (1998) 3.99
Dynamin, a membrane-remodelling GTPase. Nat Rev Mol Cell Biol (2012) 3.92
A new dynamin-like protein, ADL6, is involved in trafficking from the trans-Golgi network to the central vacuole in Arabidopsis. Plant Cell (2001) 3.01
The dynamins: redundant or distinct functions for an expanding family of related GTPases? Proc Natl Acad Sci U S A (1997) 2.98
Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle. J Virol (1992) 2.88
Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore. J Cell Biol (1993) 2.72
The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J Cell Biol (1992) 2.69
Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane. J Cell Biol (1995) 2.65
The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells. Mol Biol Cell (1999) 2.64
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol (1995) 2.46
Biochemistry and cell biology of tau protein in neurofibrillary degeneration. Cold Spring Harb Perspect Med (2012) 2.39
Dynein from Dictyostelium: primary structure comparisons between a cytoplasmic motor enzyme and flagellar dynein. J Cell Biol (1992) 2.37
A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells. J Cell Biol (1998) 2.37
Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues. Proc Natl Acad Sci U S A (1994) 2.36
Mitotic motors. J Cell Biol (1991) 2.27
Vps1p, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae. EMBO J (1993) 2.26
E.coli MukB protein involved in chromosome partition forms a homodimer with a rod-and-hinge structure having DNA binding and ATP/GTP binding activities. EMBO J (1992) 2.12
Association of a dynamin-like protein with the Golgi apparatus in mammalian cells. J Cell Biol (1996) 2.09
Phragmoplastin, a dynamin-like protein associated with cell plate formation in plants. EMBO J (1996) 2.01
Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm. J Cell Biol (1991) 1.89
Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A (1993) 1.88
Dissecting dynamin's role in clathrin-mediated endocytosis. Biochem Soc Trans (2009) 1.79
Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin. Mol Biol Cell (1992) 1.76
Inhibition of vesicular stomatitis virus mRNA synthesis by human MxA protein. J Virol (1991) 1.74
Yeast proteins associated with microtubules in vitro and in vivo. Mol Biol Cell (1992) 1.59
A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site. Blood (2012) 1.59
Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transport. J Cell Biol (1991) 1.53
Activity of rat Mx proteins against a rhabdovirus. J Virol (1990) 1.52
Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP. Mol Cell Biol (1991) 1.47
Growth factor-induced binding of dynamin to signal transduction proteins involves sorting to distinct and separate proline-rich dynamin sequences. EMBO J (1994) 1.46
Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity. J Virol (1997) 1.44
Dynamin GTPase is stimulated by crosslinking through the C-terminal proline-rich domain. EMBO J (1995) 1.42
The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting. Mol Cell Biol (1995) 1.38
Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells. J Cell Biol (1993) 1.37
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I. Proc Natl Acad Sci U S A (1994) 1.35
Endocytosis of murine norovirus 1 into murine macrophages is dependent on dynamin II and cholesterol. J Virol (2010) 1.27
Disruption of a dynamin homologue affects endocytosis, organelle morphology, and cytokinesis in Dictyostelium discoideum. Mol Biol Cell (1999) 1.27
Mechanics of dynamin-mediated membrane fission. Annu Rev Biophys (2013) 1.25
Arabidopsis dynamin-like 2 that binds specifically to phosphatidylinositol 4-phosphate assembles into a high-molecular weight complex in vivo and in vitro. Plant Physiol (2001) 1.22
Chloride intracellular channel protein CLIC4 (p64H1) binds directly to brain dynamin I in a complex containing actin, tubulin and 14-3-3 isoforms. Biochem J (2001) 1.21
Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity. J Biol Chem (2010) 1.21
A dynamin-like protein in Arabidopsis thaliana is involved in biogenesis of thylakoid membranes. EMBO J (1998) 1.16
Direct membrane retrieval into large vesicles after exocytosis in sea urchin eggs. J Cell Biol (1995) 1.13
A dynamin-like protein, ADL1, is present in membranes as a high-molecular-mass complex in Arabidopsis thaliana. Plant Physiol (1997) 1.10
Identification and characterization of the smbA gene, a suppressor of the mukB null mutant of Escherichia coli. J Bacteriol (1992) 1.10
Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules. J Cell Biol (2013) 1.09
Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol (1999) 1.08
GTP gamma S inhibits organelle transport along axonal microtubules. J Cell Biol (1993) 1.07
Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. J Biol Chem (2001) 1.05
Analysis of dynamin isoforms in mammalian brain: dynamin-1 expression is spatially and temporally regulated during postnatal development. Proc Natl Acad Sci U S A (1992) 1.03
The Arabidopsis dynamin-like proteins ADL1C and ADL1E play a critical role in mitochondrial morphogenesis. Plant Cell (2003) 1.01
Molecular characterization and in situ mRNA localization of the neural recognition molecule J1-160/180: a modular structure similar to tenascin. J Cell Biol (1993) 1.00
A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. EMBO J (1994) 1.00
Solution structure of GAP SH3 domain by 1H NMR and spatial arrangement of essential Ras signaling-involved sequence. EMBO J (1994) 0.97
Dynamin-2 function and dysfunction along the secretory pathway. Front Endocrinol (Lausanne) (2013) 0.97
Dynamin rings: not just for fission. Traffic (2013) 0.95
New insights into protein-tyrosine kinase receptor signaling complexes. Protein Sci (1993) 0.94
Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae. Mol Biol Cell (1994) 0.92
Purification and characterization of novel microtubule-associated proteins from Arabidopsis cell suspension cultures. Plant Physiol (2013) 0.91
Cloning of the rainbow trout (Oncorhynchus mykiss) Mx2 and Mx3 cDNAs and characterization of trout Mx protein expression in salmon cells. J Virol (1997) 0.89
Dynamin 3 participates in the growth and development of megakaryocytes. Exp Hematol (2008) 0.88
Resistance to influenza virus infection of Mx transgenic mice expressing Mx protein under the control of two constitutive promoters. J Virol (1992) 0.88
Probable mechanisms underlying interallelic complementation and temperature-sensitivity of mutations at the shibire locus of Drosophila melanogaster. Genetics (1998) 0.87
Role of phosphoinositides at the neuronal synapse. Subcell Biochem (2012) 0.87
Myosin I heavy chain kinase: cloning of the full-length gene and acidic lipid-dependent activation by Rac and Cdc42. Proc Natl Acad Sci U S A (1999) 0.86
Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C. J Membr Biol (2003) 0.85
Identification of differentially expressed genes associated with cotton fiber development in a chromosomal substitution line (CS-B22sh). Funct Integr Genomics (2007) 0.84
Thermal drift is enough to drive a single microtubule along its axis even in the absence of motor proteins. Biophys J (1993) 0.83
Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily. Biopolymers (2016) 0.83
Functional analysis of the human NRAMP family expressed in fission yeast. Biochem J (1999) 0.82
The significance of dynamin 2 expression for prostate cancer progression, prognostication, and therapeutic targeting. Cancer Med (2013) 0.79
Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipid. Biochem J (1998) 0.79
Differential expression of two Carassius auratus Mx genes in cultured CAB cells induced by grass carp hemorrhage virus and interferon. Immunogenetics (2004) 0.78
Cell motility. Dynamin joins the family. Nature (1990) 0.78
A high-throughput screen for chemical inhibitors of exocytic transport in yeast. Chembiochem (2010) 0.78
Amphiphysin I but not dynamin I nor synaptojanin mRNA expression increased after repeated methamphetamine administration in the rat cerebrum and cerebellum. J Neural Transm (Vienna) (2012) 0.77
Dynamin2 downregulation delays EGFR endocytic trafficking and promotes EGFR signaling and invasion in hepatocellular carcinoma. Am J Cancer Res (2015) 0.77
A membrane-bound form of glutamate dehydrogenase possesses an ATP-dependent high-affinity microtubule-binding activity. Biochem J (1993) 0.76
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1991) 0.75
Transformation of a novel direct-repeat repressor element into a promoter and enhancer by multimerisation. Nucleic Acids Res (1992) 0.75
Dynamin 2 is essential for mammalian spermatogenesis. Sci Rep (2016) 0.75
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J Cell Biol (1996) 7.65
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol (1997) 6.57
A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29
Retrograde transport by the microtubule-associated protein MAP 1C. Nature (1987) 5.06
Effects of mutant rat dynamin on endocytosis. J Cell Biol (1993) 5.05
A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J Cell Biol (1982) 4.94
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties. J Cell Biol (1987) 4.78
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature (1991) 4.69
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J Cell Biol (1995) 4.66
Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell (1989) 3.97
Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. J Biol Chem (1994) 3.89
DYNEINS: molecular structure and cellular function. Annu Rev Cell Biol (1994) 3.26
Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature (1991) 2.99
An extended microtubule-binding structure within the dynein motor domain. Nature (1997) 2.93
Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. J Biol Chem (1993) 2.91
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol (2001) 2.89
Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy. Neurology (2012) 2.56
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol (1995) 2.46
Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature (1992) 2.45
Motor proteins of cytoplasmic microtubules. Annu Rev Biochem (1990) 2.45
The herpes simplex virus 1 U(L)34 protein interacts with a cytoplasmic dynein intermediate chain and targets nuclear membrane. J Virol (2000) 2.43
Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C terminus of tubulin. Nature (1989) 2.41
Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (1997) 2.39
Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol (1984) 2.38
The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties. J Biol Chem (1978) 2.36
Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends. J Cell Sci (1999) 2.32
Microtubule-associated protein 1C from brain is a two-headed cytosolic dynein. Nature (1988) 2.26
Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Neuron (1993) 2.24
Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules. Biochemistry (1977) 2.07
Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience (1984) 2.04
Activation of dynamin GTPase by acidic phospholipids and endogenous rat brain vesicles. J Biol Chem (1993) 2.04
Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. J Cell Biol (1984) 2.03
Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J Biol Chem (1982) 2.01
A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol (1981) 1.97
Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. J Cell Biol (1983) 1.93
Emotionally expressive coping predicts psychological and physical adjustment to breast cancer. J Consult Clin Psychol (2000) 1.92
Low molecular weight microtubule-associated proteins are light chains of microtubule-associated protein 1 (MAP 1). Proc Natl Acad Sci U S A (1983) 1.90
Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain. Proc Natl Acad Sci U S A (1993) 1.88
Preparation of microtubules from rat liver and testis: cytoplasmic dynein is a major microtubule associated protein. Cell Motil Cytoskeleton (1989) 1.83
Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J Biol Chem (2000) 1.82
Reversible assembly purification of microtubules without assembly-promoting agents and further purification of tubulin, microtubule-associated proteins, and MAP fragments. Methods Enzymol (1986) 1.82
Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. J Cell Biol (1992) 1.81
Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J Cell Biol (1998) 1.80
Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton. Proc Natl Acad Sci U S A (1985) 1.72
Immunolocalization of cytoplasmic dynein to lysosomes in cultured cells. J Cell Sci (1992) 1.72
The fluorescent treponemal antibody absorption test for syphilis: a comparison with the Treponema pallidum immobilization test and the fluorescent treponemal antibody test. Med J Aust (1968) 1.72
Distinct but overlapping sites within the cytoplasmic dynein heavy chain for dimerization and for intermediate chain and light intermediate chain binding. J Biol Chem (2000) 1.69
Removal of the projections from cytoplasmic microtubules in vitro by digestion with trypsin. J Biol Chem (1977) 1.65
The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Mol Biol Cell (1997) 1.56
Isolation of sea urchin egg microtubules with taxol and identification of mitotic spindle microtubule-associated proteins with monoclonal antibodies. Proc Natl Acad Sci U S A (1983) 1.55
Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C). J Cell Biol (1988) 1.51
MAP 1A and MAP 1B are structurally related microtubule associated proteins with distinct developmental patterns in the CNS. J Neurosci (1989) 1.48
A binding site for SH3 domains targets dynamin to coated pits. J Biol Chem (1996) 1.42
Multiple distinct coiled-coils are involved in dynamin self-assembly. J Biol Chem (1999) 1.41
Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proc Natl Acad Sci U S A (1982) 1.40
Purification of microtubules and microtubule-associated proteins from sea urchin eggs and cultured mammalian cells using taxol, and use of exogenous taxol-stabilized brain microtubules for purifying microtubule-associated proteins. Methods Enzymol (1986) 1.38
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid. J Cell Biol (1994) 1.37
Neuronal abnormalities in microtubule-associated protein 1B mutant mice. Proc Natl Acad Sci U S A (1996) 1.35
Role of the basic, proline-rich region of dynamin in Src homology 3 domain binding and endocytosis. J Biol Chem (1997) 1.35
Differential expression and phosphorylation of the 74-kDa intermediate chains of cytoplasmic dynein in cultured neurons and glia. J Biol Chem (1996) 1.32
Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature (1988) 1.32
Activation of dynamin GTPase is a result of positive cooperativity. J Biol Chem (1994) 1.29
Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton. Curr Biol (2000) 1.28
Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments. J Cell Sci (1999) 1.28
Guidance of neurite outgrowth by pathways of substratum-adsorbed laminin. J Neurosci Res (1985) 1.24
Processing, characterisation and biocompatibility of iron-phosphate glass fibres for tissue engineering. Biomaterials (2004) 1.22
Dynamin forms polymeric complexes in the presence of lipid vesicles. Characterization of chemically cross-linked dynamin molecules. J Biol Chem (1995) 1.22
Fast transport and retrograde movement of huntingtin and HAP 1 in axons. Neuroreport (1997) 1.20
Developmental stage- and tissue-specific expression of shibire, a Drosophila gene involved in endocytosis. J Cell Sci (1992) 1.16
MAP2 (microtubule-associated protein 2). Cell Muscle Motil (1984) 1.16
Purification of brain microtubules and microtubule-associated protein 1 using taxol. Methods Enzymol (1986) 1.16
Purification of brain cytoplasmic dynein and characterization of its in vitro properties. Methods Enzymol (1991) 1.15
Microtubule-associated proteins: subunits of the cytomatrix. J Cell Biol (1984) 1.15
Microtubule-associated proteins 1A and LC2. Two proteins encoded in one messenger RNA. J Biol Chem (1992) 1.13
Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases. J Cell Sci (1995) 1.13
A monoclonal antibody that cross-reacts with phosphorylated epitopes on two microtubule-associated proteins and two neurofilament polypeptides. Proc Natl Acad Sci U S A (1986) 1.13
Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2. J Biol Chem (1983) 1.13
Multiple mouse chromosomal loci for dynein-based motility. Genomics (1996) 1.13
The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule-associated proteins 2A, 2B, and 2C. Neuron (1989) 1.13
MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain. Neuron (1991) 1.12
Gene localization and developmental expression of light chain 3: a common subunit of microtubule-associated protein 1A(MAP1A) and MAP1B. J Neurosci Res (1996) 1.12
Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer. Cold Spring Harb Symp Quant Biol (2008) 1.11
Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. J Biol Chem (2001) 1.05
Activation and inactivation characteristics of the sodium permeability in muscle fibres from Rana temporaria. J Physiol (1982) 1.05
Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres. Hum Mol Genet (1998) 1.02
Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins. Mol Biol Cell (1994) 1.01
In vitro motility from recombinant dynein heavy chain. Proc Natl Acad Sci U S A (1996) 1.00
Regulation of the intracellular distribution of cytoplasmic dynein by serum factors and calcium. J Cell Sci (1993) 0.98
Identification of phosphatidylinositol kinase in rat liver lysosomal membranes. J Biol Chem (1983) 0.98
Form or function? Part 1. Subjective cosmetic and functional correlates of quality of life in women treated with breast-conserving surgical procedures and radiotherapy. Cancer (2001) 0.97
Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma. Am J Pathol (2001) 0.97
Modulation of cytoplasmic dynein ATPase activity by the accessory subunits. Cell Motil Cytoskeleton (2001) 0.96