Published in Proc Natl Acad Sci U S A on March 28, 1995
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. Proc Natl Acad Sci U S A (1997) 5.51
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes Dev (1997) 4.27
Eukaryotic MCM proteins: beyond replication initiation. Microbiol Mol Biol Rev (2004) 4.19
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J (1997) 3.35
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. EMBO J (1999) 3.05
mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p. Proc Natl Acad Sci U S A (1997) 3.01
Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae. Mol Cell Biol (1996) 2.72
Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. J Cell Biol (1997) 2.58
Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2. J Cell Biol (1998) 2.51
ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae. EMBO J (1996) 2.42
Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity. Mol Cell Biol (1999) 2.42
CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication. Mol Cell Biol (1997) 2.17
A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. J Cell Biol (1997) 2.09
Cdc6 protein causes premature entry into S phase in a mammalian cell-free system. EMBO J (1998) 1.95
Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication. Proc Natl Acad Sci U S A (1996) 1.94
Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18. EMBO J (2000) 1.91
Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation. Genes Dev (2002) 1.78
Fission yeast cdc21, a member of the MCM protein family, is required for onset of S phase and is located in the nucleus throughout the cell cycle. EMBO J (1996) 1.70
MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint. Mol Biol Cell (2001) 1.58
CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication. Proc Natl Acad Sci U S A (1997) 1.56
XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication. Proc Natl Acad Sci U S A (1996) 1.53
Dbf4p, an essential S phase-promoting factor, is targeted for degradation by the anaphase-promoting complex. Mol Cell Biol (2000) 1.52
Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clb kinase activity: a mechanism for CLB cluster gene activation. Genes Dev (2003) 1.45
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly. Mol Biol Cell (1999) 1.42
Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins. Nucleic Acids Res (1995) 1.35
Characterization of Cdc47p-minichromosome maintenance complexes in Saccharomyces cerevisiae: identification of Cdc45p as a subunit. Mol Cell Biol (1997) 1.32
Identification and characterization of a human protein kinase related to budding yeast Cdc7p. Proc Natl Acad Sci U S A (1997) 1.31
Mcm2 and Mcm3 are constitutive nuclear proteins that exhibit distinct isoforms and bind chromatin during specific cell cycle stages of Saccharomyces cerevisiae. Mol Biol Cell (1997) 1.25
Drosophila MCM protein complexes. Mol Biol Cell (1996) 1.25
Identification and functional characterization of a new member of the human Mcm protein family: hMcm8. Nucleic Acids Res (2003) 1.23
Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase. J Virol (2004) 1.15
MCM7 interacts with androgen receptor. Am J Pathol (2008) 0.96
Nascent transcription of MCM2-7 is important for nuclear localization of the minichromosome maintenance complex in G1. Mol Biol Cell (2007) 0.92
Oncogenic activity of MCM7 transforming cluster. World J Clin Oncol (2011) 0.90
Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis. Mol Biol Cell (2003) 0.88
The fertilization-induced DNA replication factor MCM6 of maize shuttles between cytoplasm and nucleus, and is essential for plant growth and development. Plant Physiol (2006) 0.85
Interaction of MCM7 and RACK1 for activation of MCM7 and cell growth. Am J Pathol (2013) 0.81
Mechanisms and regulation of DNA replication initiation in eukaryotes. Crit Rev Biochem Mol Biol (2017) 0.79
Luteal activity of pregnant rats with hypo-and hyperthyroidism. J Ovarian Res (2014) 0.76
Soluble gp130 promotes intestinal epithelial hyperplasia during reovirus infection. Int J Exp Pathol (2010) 0.76
The DNA replication licensing factor miniature chromosome maintenance 7 is essential for RNA splicing of epidermal growth factor receptor, c-Met, and platelet-derived growth factor receptor. J Biol Chem (2014) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (1987) 19.68
Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol (1984) 14.58
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell (1992) 7.07
The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5. Cell (1991) 6.36
Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J (1993) 5.80
A yeast chromosomal origin of DNA replication defined by multiple functional elements. Science (1992) 5.70
A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature (1988) 5.41
The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization. Cell (1989) 4.95
Yeast origin recognition complex functions in transcription silencing and DNA replication. Science (1993) 4.85
Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae. Mol Biol Cell (1992) 4.77
Isolation of ORC6, a component of the yeast origin recognition complex by a one-hybrid system. Science (1993) 4.53
A group of interacting yeast DNA replication genes. Genes Dev (1991) 4.45
Cell cycle regulation of the human cdc2 gene. EMBO J (1992) 3.69
A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res (1993) 3.54
The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry. Cell (1990) 3.38
Subcellular localization of yeast CDC46 varies with the cell cycle. Genes Dev (1990) 3.34
Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo. Science (1994) 3.16
Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Genes Dev (1993) 2.99
Yeast origin recognition complex is involved in DNA replication and transcriptional silencing. Nature (1993) 2.76
Nuclear export of proteins: the role of nuclear retention. Cell (1993) 2.51
A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae. J Mol Biol (1991) 2.35
Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication. Nucleic Acids Res (1992) 2.27
Cell cycle control of DNA synthesis in budding yeast. Nucleic Acids Res (1992) 2.23
The MCM2-3-5 proteins: are they replication licensing factors? Trends Cell Biol (1994) 1.95
Ease of DNA unwinding is a conserved property of yeast replication origins. Nucleic Acids Res (1993) 1.95
The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae. J Biol Chem (1984) 1.72
Fission yeast genes nda1+ and nda4+, mutations of which lead to S-phase block, chromatin alteration and Ca2+ suppression, are members of the CDC46/MCM2 family. Mol Biol Cell (1993) 1.61
The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins. Nucleic Acids Res (1993) 1.46
Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle. Proc Natl Acad Sci U S A (1992) 1.45
DNA synthesis control in yeast: an evolutionarily conserved mechanism for regulating DNA synthesis genes? Bioessays (1992) 1.10
A 12.8 kb segment, on the right arm of chromosome II from Saccharomyces cerevisiae including part of the DUR1,2 gene, contains five putative new genes. Yeast (1993) 0.92
Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex. Biochem J (1998) 0.96
Kinetic properties of missense mutations in patients with glutathione synthetase deficiency. Biochem J (2000) 0.83
Life albums in long-term care: resident, family, and staff perceptions. Geriatr Nurs (2002) 0.75