Published in Mol Cell Biol on July 01, 1995
The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity. Mol Cell Biol (1997) 2.76
Mad proteins contain a dominant transcription repression domain. Mol Cell Biol (1996) 2.52
Interaction of the viral activator protein ICP4 with TFIID through TAF250. Mol Cell Biol (1996) 1.56
TFIIB and the regulation of transcription by RNA polymerase II. Chromosoma (2007) 1.53
Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4. J Virol (1995) 1.48
Repression of host RNA polymerase II transcription by herpes simplex virus type 1. J Virol (1997) 1.46
Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme. J Virol (2002) 1.43
The murine Sim-2 gene product inhibits transcription by active repression and functional interference. Mol Cell Biol (1997) 1.40
Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication. J Virol (1996) 1.17
Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription. Mol Cell Biol (1999) 1.12
Relationship between TATA-binding protein and herpes simplex virus type 1 ICP4 DNA-binding sites in complex formation and repression of transcription. J Virol (1995) 1.11
Oligomerization of ICP4 and rearrangement of heat shock proteins may be important for herpes simplex virus type 1 prereplicative site formation. J Virol (2008) 1.10
Herpes simplex virus type 1 ICP4 promotes transcription preinitiation complex formation by enhancing the binding of TFIID to DNA. J Virol (2000) 1.08
Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro. Mol Cell Biol (1996) 1.07
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4. J Virol (1996) 1.04
The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. J Virol (1998) 1.04
Identification of a novel transcriptional repressor encoded by human cytomegalovirus. J Virol (2001) 1.02
The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expression. J Virol (2002) 1.02
Herpes simplex virus 1 ICP4 forms complexes with TFIID and mediator in virus-infected cells. J Virol (2011) 1.00
Differential cellular requirements for activation of herpes simplex virus type 1 early (tk) and late (gC) promoters by ICP4. J Virol (2004) 0.99
Repression of the alpha0 gene by ICP4 during a productive herpes simplex virus infection. J Virol (1996) 0.92
DNA-dependent oligomerization of herpes simplex virus type 1 regulatory protein ICP4. J Virol (2007) 0.86
Temperature-dependent conformational changes in herpes simplex virus ICP4 that affect transcription activation. J Virol (2003) 0.85
Requirement of the N-terminal activation domain of herpes simplex virus ICP4 for viral gene expression. J Virol (2012) 0.84
Stabilized binding of TBP to the TATA box of herpes simplex virus type 1 early (tk) and late (gC) promoters by TFIIA and ICP4. J Virol (2008) 0.84
Role of the IE62 consensus binding site in transactivation by the varicella-zoster virus IE62 protein. J Virol (2010) 0.83
The N terminus and C terminus of herpes simplex virus 1 ICP4 cooperate to activate viral gene expression. J Virol (2012) 0.80
Herpesvirus Late Gene Expression: A Viral-Specific Pre-initiation Complex Is Key. Front Microbiol (2016) 0.79
Identification of a motif in the C terminus of herpes simplex virus regulatory protein ICP4 that contributes to activation of transcription. J Virol (2002) 0.78
Characterization of cis-acting elements required for autorepression of the equine herpesvirus 1 IE gene. Virus Res (2012) 0.76
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK. J Virol (1979) 11.34
Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175. J Virol (1980) 9.30
Transcriptional activation: a complex puzzle with few easy pieces. Cell (1994) 8.63
A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis. Nature (1980) 8.47
Mechanism of transcriptional activation by Sp1: evidence for coactivators. Cell (1990) 8.18
Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J Virol (1985) 8.12
Co-crystal structure of TBP recognizing the minor groove of a TATA element. Nature (1993) 7.45
Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters. J Virol (1985) 7.39
Structural features of the herpes simplex virus alpha gene 4, 0, and 27 promoter-regulatory sequences which confer alpha regulation on chimeric thymidine kinase genes. J Virol (1982) 7.35
Trans activation of transcription by herpes virus products: requirement for two HSV-1 immediate-early polypeptides for maximum activity. EMBO J (1984) 7.33
The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell (1993) 5.91
Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. Mol Cell Biol (1985) 5.76
Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. J Virol (1987) 5.71
Three trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation. J Virol (1985) 5.63
Transcriptional repression of eukaryotic promoters. Cell (1989) 5.60
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter. Genes Dev (1992) 4.85
Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4. Mol Cell Biol (1985) 4.74
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell (1993) 4.57
Cloning of a transcriptionally active human TATA binding factor. Science (1990) 4.18
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell (1994) 4.06
Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes. Proc Natl Acad Sci U S A (1984) 4.05
Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J Biol Chem (1985) 3.89
Cloning of a human gene encoding the general transcription initiation factor IIB. Nature (1991) 3.67
Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription. Cell (1992) 3.62
Initiation of transcription by RNA polymerase II: a multi-step process. Prog Nucleic Acid Res Mol Biol (1993) 3.61
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell (1994) 3.46
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell (1994) 3.43
Yeast and human TATA-binding proteins have nearly identical DNA sequence requirements for transcription in vitro. Mol Cell Biol (1990) 3.39
Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. J Biol Chem (1987) 3.38
Transcriptional control of herpesvirus gene expression: gene functions required for positive and negative regulation. Proc Natl Acad Sci U S A (1986) 3.28
The basics of basal transcription by RNA polymerase II. Cell (1994) 3.20
Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4. J Virol (1988) 3.14
Association of the herpes simplex virus regulatory protein ICP4 with specific nucleotide sequences in DNA. Nucleic Acids Res (1986) 3.09
Binding of the herpes simplex virus immediate-early gene product ICP4 to its own transcription start site. J Virol (1987) 3.09
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides. Nucleic Acids Res (1987) 2.99
Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II. Genes Dev (1993) 2.87
DNA-binding site of major regulatory protein alpha 4 specifically associated with promoter-regulatory domains of alpha genes of herpes simplex virus type 1. Proc Natl Acad Sci U S A (1986) 2.85
DNA bending and orientation-dependent function of YY1 in the c-fos promoter. Genes Dev (1993) 2.80
Functional analysis of a herpes simplex virus type 1 promoter: identification of far-upstream regulatory sequences. Nucleic Acids Res (1983) 2.78
A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell (1994) 2.31
A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1 genome. J Virol (1993) 2.28
Isolation of herpes simplex virus regulatory protein ICP4 as a homodimeric complex. J Virol (1985) 2.20
An ATP-dependent inhibitor of TBP binding to DNA. Genes Dev (1993) 2.19
ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB. J Virol (1993) 2.16
An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter. Proc Natl Acad Sci U S A (1993) 2.13
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro. Mol Cell Biol (1989) 2.06
Mutational dissection of the HSV-1 immediate-early protein Vmw175 involved in transcriptional transactivation and repression. Virology (1988) 2.03
The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes. EMBO J (1992) 1.87
Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1. J Virol (1990) 1.85
The regions of the herpes simplex virus type 1 immediate early protein Vmw175 required for site specific DNA binding closely correspond to those involved in transcriptional regulation. Nucleic Acids Res (1988) 1.78
Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region. J Virol (1993) 1.77
Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription. Genes Dev (1994) 1.63
Association of herpes simplex virus regulatory protein ICP4 with sequences spanning the ICP4 gene transcription initiation site. Nucleic Acids Res (1988) 1.60
Repression of the herpes simplex virus 1 alpha 4 gene by its gene product occurs within the context of the viral genome and is associated with all three identified cognate sites. Proc Natl Acad Sci U S A (1993) 1.56
The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infection. J Virol (1992) 1.51
Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene. J Virol (1990) 1.44
Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene. J Virol (1991) 1.37
Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein. Proc Natl Acad Sci U S A (1993) 1.30
Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein. J Virol (1993) 1.28
Substitution of a TATA box from a herpes simplex virus late gene in the viral thymidine kinase promoter alters ICP4 inducibility but not temporal expression. J Virol (1992) 1.27
Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4. J Virol (1991) 1.27
A predictive model for DNA recognition by the herpes simplex virus protein ICP4. J Mol Biol (1991) 1.25
Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoter. Proc Natl Acad Sci U S A (1993) 1.25
The role of ICP4 repressor activity in temporal expression of the IE-3 and latency-associated transcript promoters during HSV-1 infection. Virology (1994) 1.23
Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4. J Virol (1994) 1.22
trans-dominant inhibition of herpes simplex virus transcriptional regulatory protein ICP4 by heterodimer formation. J Virol (1990) 1.20
Herpes simplex virus type 1 polypeptide ICP4 bends DNA. Nucleic Acids Res (1992) 0.89
Molecular biology running into a cul-de-sac? Nature (1988) 0.76
Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J Virol (1985) 8.12
Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4. Mol Cell Biol (1985) 4.74
Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression. J Virol (1984) 3.76
Linker-insertion nonsense and restriction-site deletion mutations of the gB glycoprotein gene of herpes simplex virus type 1. J Virol (1987) 3.51
Nucleotide sequence specifying the glycoprotein gene, gB, of herpes simplex virus type 1. Virology (1984) 3.34
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides. Nucleic Acids Res (1987) 2.99
Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins. J Virol (1998) 2.97
Nucleotide sequence of a region of the herpes simplex virus type 1 gB glycoprotein gene: mutations affecting rate of virus entry and cell fusion. Virology (1984) 2.95
Mutations in herpes simplex virus type 1 genes encoding VP5 and VP23 abrogate capsid formation and cleavage of replicated DNA. J Virol (1993) 2.79
Herpes simplex virus type 1 VP26 is not essential for replication in cell culture but influences production of infectious virus in the nervous system of infected mice. Virology (1998) 2.17
ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB. J Virol (1993) 2.16
The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27. J Virol (1997) 2.06
Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0. J Virol (1999) 1.84
Interaction of the viral activator protein ICP4 with TFIID through TAF250. Mol Cell Biol (1996) 1.56
Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4. J Virol (1995) 1.48
Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene. J Virol (1990) 1.44
Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22. J Virol (1996) 1.40
Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene. J Virol (1991) 1.37
Gene transfer to neurons using herpes simplex virus-based vectors. Annu Rev Neurosci (1996) 1.35
A fresh look at augmenter of liver regeneration in rats. Hepatology (1999) 1.32
Substitution of a TATA box from a herpes simplex virus late gene in the viral thymidine kinase promoter alters ICP4 inducibility but not temporal expression. J Virol (1992) 1.27
Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4. J Virol (1991) 1.27
Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoter. Proc Natl Acad Sci U S A (1993) 1.25
The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes. J Virol (1989) 1.22
Development and application of herpes simplex virus vectors for human gene therapy. Annu Rev Microbiol (1995) 1.22
Intragenic complementation among partial peptides of herpes simplex virus regulatory protein ICP4. J Virol (1989) 1.20
trans-dominant inhibition of herpes simplex virus transcriptional regulatory protein ICP4 by heterodimer formation. J Virol (1990) 1.20
A second-site revertant of a defective herpes simplex virus ICP4 protein with restored regulatory activities and impaired DNA-binding properties. J Virol (1991) 1.19
Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival. J Virol (2001) 1.17
Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication. J Virol (1996) 1.17
Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol (1990) 1.13
Relationship between TATA-binding protein and herpes simplex virus type 1 ICP4 DNA-binding sites in complex formation and repression of transcription. J Virol (1995) 1.11
Herpes simplex virus for gene delivery to neurons. New Biol (1991) 1.05
The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. J Virol (1998) 1.04
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4. J Virol (1996) 1.04
Immunogenicity of herpes simplex virus type 1 mutants containing deletions in one or more alpha-genes: ICP4, ICP27, ICP22, and ICP0. Virology (1999) 0.91
Pyruvate inhibits the chronic damage which ensues after ischemia/reperfusion injury of kidneys. Transplant Proc (1999) 0.89
Induction of transcription by a viral regulatory protein depends on the relative strengths of functional TATA boxes. Mol Cell Biol (1995) 0.85
Initiator elements and regulated expression of the herpes simplex virus thymidine kinase gene. J Virol (1995) 0.82
Transdominant inhibition of herpes simplex virus growth in transgenic mice. Virology (1992) 0.81
Design and application of HSV vectors for neuroprotection. Gene Ther (2000) 0.81
Herpes simplex virus vectors and gene transfer to brain. Dev Biol Stand (1994) 0.80
Endotoxin causes up-regulation of endothelin receptors in cultured hepatic stellate cells via nitric oxide-dependent and -independent mechanisms. Br J Pharmacol (2000) 0.78
Gene transfer to brain using herpes simplex virus vectors. Ann Neurol (1994) 0.78
Prevention of T-cell activation by rhCTLA4-Ig and anti-CD40L monoclonal antibody results in indefinite islet allograft survival. Transplant Proc (1999) 0.76
Ischemia/reperfusion injury induces chronic changes in the small bowel. Transplant Proc (2000) 0.75
Donor bone marrow infusion in liver recipients: effect on the occurrence of acute cellular rejection. Transplant Proc (2001) 0.75
Mechanisms underlying the development of T-cell tolerance following interruption of signalling at the CD28/B7 and CD40/gp39 interface. Transplant Proc (1999) 0.75
Xenogeneic humoral graft-Vs-host disease following hamster-to-Rat bone marrow transplantation. Transplant Proc (2000) 0.75
Central nervous system tuberculosis and adjuvant corticosteroid therapy. Mymensingh Med J (2009) 0.75
Radiologic evaluation of hyperacute brain infarction: a review. Mymensingh Med J (2014) 0.75
The combined use of sublethal irradiation and costimulatory blockade to generate mixed bone marrow chimeras. Transplant Proc (1999) 0.75
Administration of CTLA4-Ig enhances the incidence of hamster-to-rat xenogeneic bone marrow engraftment and alters the presentation of graft-vs-host disease. Transplant Proc (2000) 0.75