Structure and function of the b/HLH/Z domain of USF.

PubWeight™: 3.70‹?› | Rank: Top 1%

🔗 View Article (PMC 394791)

Published in EMBO J on January 01, 1994

Authors

A R Ferré-D'Amaré1, P Pognonec, R G Roeder, S K Burley

Author Affiliations

1: Laboratories of Molecular Biophysics, Rockefeller University, New York, NY 10021.

Articles citing this

(truncated to the top 100)

Global mapping of protein-DNA interactions in vivo by digital genomic footprinting. Nat Methods (2009) 10.17

c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol (1999) 8.17

An expansive human regulatory lexicon encoded in transcription factor footprints. Nature (2012) 7.27

The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell (2003) 5.68

Origins of specificity in protein-DNA recognition. Annu Rev Biochem (2010) 4.43

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J (1996) 3.25

Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol Cell Biol (1995) 3.10

Intrinsic disorder in transcription factors. Biochemistry (2006) 3.06

Binding of disparate transcriptional activators to nucleosomal DNA is inherently cooperative. Mol Cell Biol (1995) 2.73

Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism. Mol Cell Biol (1997) 2.68

The rice tapetum degeneration retardation gene is required for tapetum degradation and anther development. Plant Cell (2006) 2.62

Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. EMBO J (1994) 2.32

Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science (2012) 2.20

Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. Cell Rep (2013) 2.03

Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition. EMBO J (1997) 2.01

Probing the solution structure of the DNA-binding protein Max by a combination of proteolysis and mass spectrometry. Protein Sci (1995) 1.90

DNA recognition code of transcription factors in the helix-turn-helix, probe helix, hormone receptor, and zinc finger families. Proc Natl Acad Sci U S A (1994) 1.90

Chromatin structure modulation in Saccharomyces cerevisiae by centromere and promoter factor 1. Mol Cell Biol (1994) 1.74

Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. EMBO J (1997) 1.72

Act1, an NF-kappa B-activating protein. Proc Natl Acad Sci U S A (2000) 1.70

Characterization of JAZ-interacting bHLH transcription factors that regulate jasmonate responses in Arabidopsis. J Exp Bot (2011) 1.66

Genome-wide classification and evolutionary analysis of the bHLH family of transcription factors in Arabidopsis, poplar, rice, moss, and algae. Plant Physiol (2010) 1.66

Separation of phylogenetic and functional associations in biological sequences by using the parametric bootstrap. Proc Natl Acad Sci U S A (2000) 1.65

Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol Cell Biol (1996) 1.65

Assembly of a bZIP-bHLH transcription activation complex: formation of the yeast Cbf1-Met4-Met28 complex is regulated through Met28 stimulation of Cbf1 DNA binding. EMBO J (1997) 1.63

Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells. EMBO J (1998) 1.62

Base preferences for DNA binding by the bHLH-Zip protein USF: effects of MgCl2 on specificity and comparison with binding of Myc family members. Nucleic Acids Res (1994) 1.61

Targeting the microphthalmia basic helix-loop-helix-leucine zipper transcription factor to a subset of E-box elements in vitro and in vivo. Mol Cell Biol (1998) 1.59

The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist. Mol Cell Biol (1997) 1.56

An overview of MYC and its interactome. Cold Spring Harb Perspect Med (2014) 1.53

Identifying DNA-binding proteins using structural motifs and the electrostatic potential. Nucleic Acids Res (2004) 1.50

Overlapping roles and asymmetrical cross-regulation of the USF proteins in mice. Proc Natl Acad Sci U S A (1998) 1.47

Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae. Nucleic Acids Res (1995) 1.46

Differential repression of transcription factor binding by histone H1 is regulated by the core histone amino termini. EMBO J (1994) 1.43

Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus. Genetics (2000) 1.37

Structural basis of DNA bending and oriented heterodimer binding by the basic leucine zipper domains of Fos and Jun. Proc Natl Acad Sci U S A (1997) 1.34

Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Genes Dev (2000) 1.31

Distinct roles of the molecular chaperone hsp90 in modulating dioxin receptor function via the basic helix-loop-helix and PAS domains. Mol Cell Biol (1995) 1.30

Regulation of phosphate acquisition in Saccharomyces cerevisiae. Curr Genet (2003) 1.28

Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. EMBO J (1997) 1.25

Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor. Mol Cell Biol (1998) 1.25

c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene. Nucleic Acids Res (1997) 1.20

mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell. Dev Biol (2010) 1.19

Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants. Nucleic Acids Res (2011) 1.15

A general method to design dominant negatives to B-HLHZip proteins that abolish DNA binding. Proc Natl Acad Sci U S A (1997) 1.15

Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. EMBO J (2008) 1.14

Polyamines alter sequence-specific DNA-protein interactions. Nucleic Acids Res (1995) 1.14

The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction. Mol Cell Biol (1994) 1.12

Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations. Mol Cell Biol (2000) 1.11

The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate. Mol Cell Biol (1995) 1.09

Interaction of yeast kinetochore proteins with centromere-protein/transcription factor Cbf1. Proc Natl Acad Sci U S A (2000) 1.09

TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription. Nucleic Acids Res (1995) 1.08

Identification of specific DNA binding residues in the TCP family of transcription factors in Arabidopsis. Plant Cell (2010) 1.06

The semidominant Mi(b) mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerization. EMBO J (1996) 1.04

A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription. Nucleic Acids Res (2006) 1.02

Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1. J Virol (1995) 1.02

Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors. Mol Cell Biol (2005) 1.00

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice. Elife (2013) 0.98

Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA. Cell Res (2012) 0.97

Specificity of DNA binding of the c-Myc/Max and ARNT/ARNT dimers at the CACGTG recognition site. Nucleic Acids Res (1999) 0.97

Comparing the yeast retrograde response and NF-κB stress responses: implications for aging. Aging Cell (2010) 0.96

Purification and identification of a transcription factor, USF-2, binding to E-box element in the promoter of human telomerase reverse transcriptase (hTERT). Proteomics (2010) 0.96

Target gene specificity of USF-1 is directed via p38-mediated phosphorylation-dependent acetylation. J Biol Chem (2009) 0.95

Regulatory module network of basic/helix-loop-helix transcription factors in mouse brain. Genome Biol (2007) 0.93

Analysis of the DNA-binding and dimerization activities of Neurospora crassa transcription factor NUC-1. Mol Cell Biol (1994) 0.92

The leucine zipper may induce electrophoretic mobility anomalies without DNA bending. Proc Natl Acad Sci U S A (1996) 0.91

Phylogenetic analysis and classification of the fungal bHLH domain. Mol Biol Evol (2011) 0.90

Role of helix-loop-helix proteins during differentiation of erythroid cells. Mol Cell Biol (2011) 0.90

Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res (2001) 0.90

Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions. Biochemistry (2005) 0.89

Evolution of fruit development genes in flowering plants. Front Plant Sci (2014) 0.88

Determinants of the DNA binding specificity of class I and class II TCP transcription factors. J Biol Chem (2011) 0.88

Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics (2015) 0.87

Heteronuclear (1H, 13C, 15N) NMR assignments and secondary structure of the basic region-helix-loop-helix domain of E47. Protein Sci (1997) 0.87

Backbone dynamics of sequence specific recognition and binding by the yeast Pho4 bHLH domain probed by NMR. Protein Sci (2000) 0.86

Characterization of the dimerization domain in BglG, an RNA-binding transcriptional antiterminator from Escherichia coli. J Bacteriol (1999) 0.86

Transcriptional plasticity through differential assembly of a multiprotein activation complex. Nucleic Acids Res (2010) 0.86

Upstream stimulatory factor regulates major histocompatibility complex class I gene expression: the U2DeltaE4 splice variant abrogates E-box activity. Mol Cell Biol (1999) 0.86

Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition. Proc Natl Acad Sci U S A (1995) 0.85

Altered DNA binding specificity of Arnt by selection of partner bHLH-PAS proteins. Nucleic Acids Res (2004) 0.85

Redox modulation of plant developmental regulators from the class I TCP transcription factor family. Plant Physiol (2013) 0.85

Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation. Nat Commun (2015) 0.83

In vivo identification of promoter elements and transcription factors mediating activation of hepatic HMG-CoA reductase by T3. Biochem Biophys Res Commun (2009) 0.83

Identification and functional analysis of a second RBF-2 binding site within the HIV-1 promoter. Virology (2011) 0.83

Functional diversification of a basic helix-loop-helix protein due to alternative transcription during generation of amphidiploidy in tobacco plants. Biochem J (2007) 0.83

Rationally designed coiled-coil DNA looping peptides control DNA topology. Nucleic Acids Res (2013) 0.82

Computational modeling on the recognition of the HRE motif by HIF-1: molecular docking and molecular dynamics studies. J Mol Model (2011) 0.81

Mitfmi-enu122 is a missense mutation in the HLH dimerization domain. Mamm Genome (1998) 0.81

Crystal structure of the minimalist Max-E47 protein chimera. PLoS One (2012) 0.81

Characterization of the distal promoter of the human pyruvate carboxylase gene in pancreatic beta cells. PLoS One (2013) 0.80

CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes. Retrovirology (2012) 0.80

The E12 inhibitory domain prevents homodimer formation and facilitates selective heterodimerization with the MyoD family of gene regulatory factors. EMBO J (1995) 0.80

MYB82 functions in regulation of trichome development in Arabidopsis. J Exp Bot (2014) 0.80

MyoD forms micelles which can dissociate to form heterodimers with E47: implications of micellization on function. Proc Natl Acad Sci U S A (1995) 0.80

Classification and evolutionary analysis of the basic helix-loop-helix gene family in the green anole lizard, Anolis carolinensis. Mol Genet Genomics (2013) 0.79

Yersinia enterocolitica YopT and Clostridium difficile toxin B induce expression of GILZ in epithelial cells. PLoS One (2012) 0.79

Induction of transcripts derived from promoter III of the acetyl-CoA carboxylase-alpha gene in mammary gland is associated with recruitment of SREBP-1 to a region of the proximal promoter defined by a DNase I hypersensitive site. Biochem J (2003) 0.79

Max-E47, a designed minimalist protein that targets the E-box DNA site in vivo and in vitro. J Am Chem Soc (2009) 0.78

Functional interaction between TATA and upstream CACGTG elements regulates the temporally specific expression of Otx mRNAs during early embryogenesis of the sea urchin, Hemicentrotus pulcherrimus. Nucleic Acids Res (2002) 0.78

Genomic cloning and characterization of the rat glutathione S-transferase-A3-subunit gene. Biochem J (1999) 0.77

Articles cited by this

Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A (1991) 119.63

Spectroscopic determination of tryptophan and tyrosine in proteins. Biochemistry (1967) 21.79

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell (1989) 21.54

How eukaryotic transcriptional activators work. Nature (1988) 19.34

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell (1985) 13.36

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science (1991) 12.00

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell (1985) 10.06

Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (1978) 9.60

Estimation of globular protein secondary structure from circular dichroism. Biochemistry (1981) 9.14

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature (1993) 7.41

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex. Cell (1992) 6.47

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell (1993) 6.40

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. Genes Dev (1990) 6.00

Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell (1991) 5.76

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity. Cell (1993) 5.28

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy. Cell (1990) 4.59

Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science (1991) 4.45

Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem (1988) 3.96

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev (1990) 3.44

Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins. Proc Natl Acad Sci U S A (1992) 3.25

A helix-loop-helix protein related to the immunoglobulin E box-binding proteins. Mol Cell Biol (1990) 2.90

Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. EMBO J (1985) 2.83

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein. Nature (1989) 2.70

Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J (1993) 2.45

Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif. EMBO J (1992) 2.34

Molecular characterization of helix-loop-helix peptides. Science (1992) 2.26

Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF. Mol Cell Biol (1991) 2.04

An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. EMBO J (1990) 1.99

Interactions of coiled coils in transcription factors: where is the specificity? Curr Opin Genet Dev (1993) 1.94

TFEB has DNA-binding and oligomerization properties of a unique helix-loop-helix/leucine-zipper family. Genes Dev (1991) 1.90

Multiple forms of the human gene-specific transcription factor USF. II. DNA binding properties and transcriptional activity of the purified HeLa USF. J Biol Chem (1988) 1.83

The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity. Genes Dev (1991) 1.78

High affinity DNA-binding Myc analogs: recognition by an alpha helix. Cell (1993) 1.57

Recombinant yeast TFIID, a general transcription factor, mediates activation by the gene-specific factor USF in a chromatin assembly assay. Proc Natl Acad Sci U S A (1990) 1.35

Carboxyl-carboxylate interactions in proteins. Nature (1982) 1.34

A quick procedure for purification of functional recombinant proteins over-expressed in E.coli. Nucleic Acids Res (1991) 1.33

Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor groove. Proc Natl Acad Sci U S A (1992) 1.30

The bidirectional upstream element of the adenovirus-2 major late promoter binds a single monomeric molecule of the upstream factor. EMBO J (1987) 1.30

Opposite orientations of DNA bending by c-Myc and Max. Proc Natl Acad Sci U S A (1992) 1.27

The Xenopus B1 factor is closely related to the mammalian activator USF and is implicated in the developmental regulation of TFIIIA gene expression. Mol Cell Biol (1991) 1.20

The helix-loop-helix/leucine repeat transcription factor USF can be functionally regulated in a redox-dependent manner. J Biol Chem (1992) 1.16

Transcription factor eUSF is an essential component of isolated transcription complexes on the duck histone H5 gene and it mediates the interaction of TFIID with a TATA-deficient promoter. J Mol Biol (1992) 1.09

Articles by these authors

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30

Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell (1985) 13.36

Weight-reducing effects of the plasma protein encoded by the obese gene. Science (1995) 13.05

Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. J Biol Chem (1979) 11.68

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes. Cell (1980) 10.87

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. J Biol Chem (1980) 10.78

Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. J Biol Chem (1980) 10.63

Eukaryotic gene transcription with purified components. Methods Enzymol (1983) 9.71

Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system. Cell (1980) 8.02

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature (1993) 7.56

Co-crystal structure of TBP recognizing the minor groove of a TATA element. Nature (1993) 7.45

Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell (1980) 7.42

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature (1993) 7.41

Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol (1981) 7.12

Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol Cell Biol (1983) 7.01

Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature (1969) 6.98

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A (1985) 6.94

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88

Aromatic-aromatic interaction: a mechanism of protein structure stabilization. Science (1985) 6.87

Transcription of class III genes: formation of preinitiation complexes. Science (1983) 6.79

Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63

DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A (1982) 6.57

Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (1970) 6.39

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol (1988) 5.60

Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev (2001) 5.37

Biochemistry and structural biology of transcription factor IID (TFIID). Annu Rev Biochem (1996) 5.19

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell (1987) 5.04

Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature (1995) 4.93

Crystal structure of TFIID TATA-box binding protein. Nature (1992) 4.85

Winged helix proteins. Curr Opin Struct Biol (2000) 4.80

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP. Cell (1997) 4.75

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc Natl Acad Sci U S A (1988) 4.72

Specific nucleolar and nucleoplasmic RNA polymerases. Proc Natl Acad Sci U S A (1970) 4.63

Synergistic activation of transcription by CBP and p53. Nature (1997) 4.54

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II. Cell (1987) 4.37

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro. Cell (1987) 4.37

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A (1988) 4.33

Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell (1984) 4.32

A standard reference frame for the description of nucleic acid base-pair geometry. J Mol Biol (2001) 4.29

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell (1988) 4.15

Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature (1991) 4.09

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site. J Biol Chem (1987) 4.08

Inducible binding of a factor to the c-fos enhancer. Cell (1986) 3.98

Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem (1988) 3.96

A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature (1988) 3.95

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J Biol Chem (1985) 3.89

Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. J Biol Chem (1974) 3.84

Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Proc Natl Acad Sci U S A (1986) 3.81

Recognition of polyadenylate RNA by the poly(A)-binding protein. Cell (1999) 3.76

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature (1989) 3.74

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci U S A (1996) 3.61

Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Cell (2000) 3.59

c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol (1987) 3.52

Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science (1995) 3.50

Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res (1991) 3.48

Amino-aromatic interactions in proteins. FEBS Lett (1986) 3.47

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell (1999) 3.47

The structure of the human histone genes: clustered but not tandemly repeated. Cell (1981) 3.47

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell (1994) 3.43

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature (1990) 3.42

Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. Science (1988) 3.40

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. J Biol Chem (1987) 3.38

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity. Cell (1991) 3.36

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol (2001) 3.31

Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus. Cell (1985) 3.21

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. Mol Cell (1999) 3.21

Family of proteins that interact with TFIID and regulate promoter activity. Cell (1991) 3.20

Mechanism of action of a yeast activator: direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions. Cell (1988) 3.17

The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell (1981) 3.15

Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes. Proc Natl Acad Sci U S A (1974) 3.14

Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem Sci (2000) 3.03

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences. Nat Genet (1994) 2.97

Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta. Nature (1995) 2.96

Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection. Proc Natl Acad Sci U S A (1974) 2.95

Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. J Biol Chem (1987) 2.95

Formation of a rate-limiting intermediate in 5S RNA gene transcription. Cell (1985) 2.94

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature (1996) 2.92

Direct interaction of human TFIID with the HIV-1 transactivator tat. Nature (1994) 2.87

Activation of transcription factor IIIC by the adenovirus E1A protein. Cell (1988) 2.86

HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev (1992) 2.85

Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. EMBO J (1998) 2.81

Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Isolation and partial characterization. J Biol Chem (1974) 2.80

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc Natl Acad Sci U S A (1998) 2.76

Multiple factors involved in the transcription of class III genes in Xenopus laevis. J Biol Chem (1982) 2.75

Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol Cell Biol (1995) 2.74

A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol Cell (1999) 2.71

Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A (1988) 2.70

Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Mol Cell Biol (1986) 2.69

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol Cell (2000) 2.68

Purification of the c-fos enhancer-binding protein. Mol Cell Biol (1987) 2.64

The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes Dev (1988) 2.60

Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature (1996) 2.58

Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation. Cell (1980) 2.58