Published in Science on March 03, 1995
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In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci U S A (1996) 1.58
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The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold. PLoS Pathog (2012) 1.20
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Anti-inflammatory cytokines in asthma and allergy: interleukin-10, interleukin-12, interferon-gamma. Mediators Inflamm (2001) 1.17
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Functional differences between Stat3alpha and Stat3beta. Mol Cell Biol (1997) 1.11
Comparison of the transactivation domains of Stat5 and Stat6 in lymphoid cells and mammary epithelial cells. Mol Cell Biol (1997) 1.11
STAT signaling in the pathogenesis and treatment of cancer. Mol Med (1999) 1.11
Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors. Proc Natl Acad Sci U S A (2000) 1.10
Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs. Mol Cell Biol (1997) 1.08
Cytoplasmic STAT proteins associate prior to activation. Biochem J (2000) 1.06
Reflections on STAT3, STAT5, and STAT6 as fat STATs. Proc Natl Acad Sci U S A (1996) 1.05
A novel role for IFN-stimulated gene factor 3II in IFN-γ signaling and induction of antiviral activity in human cells. J Immunol (2010) 1.04
STAT signaling in mammary gland differentiation, cell survival and tumorigenesis. Mol Cell Endocrinol (2013) 1.04
Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. Mol Cell Biol (2002) 1.03
Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J Cell Biol (1998) 1.02
Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions. Biochem J (1998) 1.02
Stat1 associates with c-kit and is activated in response to stem cell factor. Biochem J (1997) 1.01
Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain. Mol Immunol (2006) 1.01
Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19. J Biol Chem (1999) 1.00
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Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades. J Cell Biol (2008) 0.94
STAT signaling in the pathogenesis and treatment of myeloid malignancies. JAKSTAT (2012) 0.92
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Receptor-associated constitutive protein tyrosine phosphatase activity controls the kinase function of JAK1. Proc Natl Acad Sci U S A (1997) 0.91
Cucurbitacins - a promising target for cancer therapy. Int J Health Sci (Qassim) (2013) 0.91
IFN-Gamma Inhibits JC Virus Replication in Glial Cells by Suppressing T-Antigen Expression. PLoS One (2015) 0.89
Replication of Toxoplasma gondii, but not Trypanosoma cruzi, is regulated in human fibroblasts activated with gamma interferon: requirement of a functional JAK/STAT pathway. Infect Immun (1999) 0.89
STAT heterodimers in immunity: A mixed message or a unique signal? JAKSTAT (2013) 0.89
Biologic functions of the IFN-gamma receptors. Allergy (1999) 0.87
CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production. PLoS Pathog (2013) 0.82
Dysregulation of janus kinases and signal transducers and activators of transcription in cancer. Am J Cancer Res (2011) 0.80
STAT3 signaling in immunity. Cytokine Growth Factor Rev (2016) 0.80
Suppression of dual specificity phosphatase I expression inhibits hepatitis C virus replication. PLoS One (2015) 0.79
Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling. BMC Bioinformatics (2013) 0.78
Targeted Therapies in Liver Fibrosis: Combining the Best Parts of Platelet-Derived Growth Factor BB and Interferon Gamma. Front Med (Lausanne) (2015) 0.78
Recrudescence mechanisms and gene expression profile of the reproductive tracts from chickens during the molting period. PLoS One (2013) 0.76
IFN-gamma down-regulates Secretoglobin 3A1 gene expression. Biochem Biophys Res Commun (2009) 0.76
STAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling Pathways. PLoS Biol (2016) 0.76
Antagonism of type I interferon by flaviviruses. Biochem Biophys Res Commun (2017) 0.75
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