Published in J Biol Chem on March 03, 1995
Caspases: the executioners of apoptosis. Biochem J (1997) 11.99
Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc Natl Acad Sci U S A (1996) 2.31
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis. Biochem J (1996) 2.05
Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J Exp Med (1995) 1.75
Regulation of Ich-1 pre-mRNA alternative splicing and apoptosis by mammalian splicing factors. Proc Natl Acad Sci U S A (1998) 1.60
Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis. J Nucl Cardiol (2009) 1.60
Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J Cell Biol (1996) 1.59
The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy. J Exp Med (1995) 1.47
Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer. Genes Dev (2001) 1.21
Inhibition of interleukin 1 beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP. Proc Natl Acad Sci U S A (1996) 1.19
Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis. Mol Cell Biol (2000) 1.05
Human vascular smooth muscle cells express interleukin-1beta-converting enzyme (ICE), but inhibit processing of the interleukin-1beta precursor by ICE. J Exp Med (1997) 0.84
Alternatively spliced caspase-6B isoform inhibits the activation of caspase-6A. J Biol Chem (2010) 0.83
Caspase-1 and IL-1β processing in a teleost fish. PLoS One (2012) 0.81
Apoptosis: A Current Molecular Analysis. Pathol Oncol Res (1996) 0.77
Reduced expression of the ICE-related protease CPP32 is associated with radiation-induced cisplatin resistance in HeLa cells. Br J Cancer (1997) 0.76
Interleukin-1beta-converting enzyme (ICE) and related cell death genes ICErel-II and ICErel-III map to the same PAC clone at band 11q22.2-22.3. Mamm Genome (1997) 0.76
Expression of Caspase-1 Gene Transcript Variant mRNA in Peripheral Blood Mononuclear Cells of Patients with Primary Gout in Different TCM Syndromes. Evid Based Complement Alternat Med (2015) 0.75
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature (2001) 6.62
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem (1994) 5.51
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol Cell (1998) 5.06
Ligandin: a hepatic protein which binds steroids, bilirubin, carcinogens and a number of exogenous organic anions. Nature (1971) 3.93
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. Cell Death Differ (2006) 3.77
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci U S A (1996) 3.53
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem (2001) 3.37
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature (1999) 2.95
Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci U S A (1996) 2.65
Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res (1995) 2.56
Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc Natl Acad Sci U S A (1996) 2.31
Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells. Proc Natl Acad Sci U S A (1992) 2.28
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J Biol Chem (1997) 2.26
The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32. J Biol Chem (1996) 2.07
Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci U S A (2008) 2.06
DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis. EMBO J (1996) 1.97
Nucleotides and two functional states of hsp90. J Biol Chem (1997) 1.96
FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J Biol Chem (1997) 1.86
Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids. Proc Natl Acad Sci U S A (1973) 1.84
Induction of cytolysis of cultured lymphoma cells by adenosine 3':5'-cyclic monophosphate and the isolation of resistant variants. Proc Natl Acad Sci U S A (1973) 1.61
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. J Biol Chem (2000) 1.58
CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP. Cancer Res (1997) 1.57
Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias. Cancer Res (1992) 1.54
Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits. J Biol Chem (1998) 1.52
Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation. Biochemistry (1996) 1.50
11Beta-hydroxysteroid dehydrogenase, mineralocorticoid receptor, and thiazide-sensitive Na-Cl cotransporter expression by distal tubules. J Am Soc Nephrol (1998) 1.46
Isolation and properties of cortisol metabolite binding proteins of rat liver cytosol. Biochemistry (1969) 1.42
Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization. J Biol Chem (2000) 1.39
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Res (1999) 1.36
Ligandin, the glutathione S-transferases, and chemically induced hepatocarcinogenesis: a review. Cancer Res (1977) 1.33
Calpain activation is upstream of caspases in radiation-induced apoptosis. Cell Death Differ (1998) 1.31
Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity. J Biol Chem (1998) 1.30
Processing of the Nedd2 precursor by ICE-like proteases and granzyme B. Genes Cells (1996) 1.23
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J Neurosci (1997) 1.19
Glucocorticoid-induced apoptosis in lymphocytes. Biochem Biophys Res Commun (2000) 1.18
Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35. J Biol Chem (1997) 1.17
Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. Blood (2001) 1.13
CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. J Biol Chem (1999) 1.11
Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s). J Biol Chem (1990) 1.11
Subcellular distribution of tyrosine aminotransferase in rat brain. Arch Biochem Biophys (1969) 1.10
Heteronuclear ribonucleoproteins C1 and C2, components of the spliceosome, are specific targets of interleukin 1beta-converting enzyme-like proteases in apoptosis. J Biol Chem (1996) 1.10
Coenzyme dissociation, a possible determinant of short half-life of inducible enzymes in mammalian liver. Biochem Biophys Res Commun (1973) 1.09
Translation in vitro of rat liver messenger RNA coding for ligandin (glutathione S-transferase B). Proc Natl Acad Sci U S A (1977) 1.07
The effects of 1,10-phenanthroline on the binding of activated rat hepatic glucocorticoid-receptor complexes to deoxyribonucleic acid-cellulose. Endocrinology (1981) 1.06
Overexpression and characterization of the human mineralocorticoid receptor. J Biol Chem (1991) 1.06
Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist. J Biol Chem (1998) 1.03
Cortisol metabolite binder. I. Identity with the dimethylaminoazobenzene binding protein of liver cytosol. Biochem Biophys Res Commun (1970) 1.03
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase. J Biol Chem (1971) 1.03
Effect of pyridoxal phosphate on the DNA binding site of activated hepatic glucocorticoid receptor. J Biol Chem (1978) 1.03
Liver cytosol corticosteroid binder II, a hormone receptor. J Biol Chem (1973) 1.01
Activation of the rat liver glucocorticoid--receptor complex. Biochemistry (1977) 0.98
The steroid binding domain influences intracellular solubility of the baculovirus overexpressed glucocorticoid and mineralocorticoid receptors. Biochemistry (1993) 0.97
Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. Oncogene (2001) 0.97
Rat liver adenosine triphosphate: adenosine monophosphate phosphotransferase activity. I. Purification and physical and kinetic characterization of adenylate kinase 3. J Biol Chem (1970) 0.96
Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC. Cell Death Differ (2002) 0.96
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila. Cell Death Differ (2008) 0.95
Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae. J Biol Chem (1999) 0.94
Regulation of the human Na/K-ATPase beta1 gene promoter by mineralocorticoid and glucocorticoid receptors. J Biol Chem (1998) 0.94
Rat ligandin mRNA molecular cloning and sequencing. Arch Biochem Biophys (1983) 0.94
Effects of calf intestinal alkaline phosphatase, phosphatase inhibitors, and phosphorylated compounds on the rate of activation of glucocorticoid-receptor complexes. Biochemistry (1980) 0.93
Kinetic studies and active site-binding properties of glutathione S-transferase using spin-labeled glutathione, a product analogue. J Biol Chem (1984) 0.93
Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease. J Biol Chem (1989) 0.92
Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system. J Biol Chem (1991) 0.92
Regulation of the corticosteroid inducibility of tyrosine aminotransferase in interspecific hybrid cells. Nature (1974) 0.91
Characterization of the rat colonic aldosterone receptor and its activation process. J Biol Chem (1986) 0.91
Inhibition of TRAIL-induced apoptosis by IL-8 is mediated by the p38-MAPK pathway in OVCAR3 cells. Apoptosis (2005) 0.90
Electron microscopic observations of the early effects of cortisol on the liver cell of the adrenalectomized rat. Exp Cell Res (1968) 0.90
Glucocorticoid stimulation of sodium absorption in colon epithelia is mediated by corticosteroid IB receptor. J Biol Chem (1984) 0.90
Demonstration of nuclear translocation of the mineralocorticoid receptor (MR) using an anti-MR antibody and confocal laser scanning microscopy. Mol Endocrinol (1993) 0.89
Adenosine triphosphate: adenosine monophosphate phosphotransferase isozymes in rat liver and hepatomas. Cancer Res (1970) 0.89
Physical measurements of the liver glucocorticoid receptor. Biochem J (1978) 0.88
Resolution of activated and unactivated forms of the glucocorticoid receptor from rat liver. Arch Biochem Biophys (1977) 0.87
Transcriptional regulation of the human Na/K ATPase via the human mineralocorticoid receptor. Mol Cell Biochem (2000) 0.87
Studies on the tyrosine aminotransferase mechanism. Biochemistry (1968) 0.87
FKBP46, a novel Sf9 insect cell nuclear immunophilin that forms a protein-kinase complex. J Biol Chem (1994) 0.87
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging. Cell Death Differ (2012) 0.86
Identification of a mineralocorticoid/glucocorticoid response element in the human Na/K ATPase alpha1 gene promoter. Biochem Biophys Res Commun (1999) 0.86
Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing. J Exp Med (1996) 0.86
The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52. Recept Signal Transduct (1997) 0.85
Basic amino acids stimulate the activation of the glucocorticoid--receptor complex. FEBS Lett (1977) 0.85
Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter. Biochemistry (1993) 0.85
Purification of the unactivated glucocorticoid receptor and its subsequent in vitro activation. J Biol Chem (1984) 0.85
Involvement of a low molecular weight component(s) in the mechanism of action of the glucocorticoid receptor. Biochem Biophys Res Commun (1976) 0.84
Macromolecular binding of (5,6-3H) prostaglandin E1 in liver cytosol in vitro. Biochem Biophys Res Commun (1973) 0.84
Activation of the glucocorticoid-receptor complex. Physiol Rev (1982) 0.84
Monoclonal antibodies to the glucocorticoid receptor. Endocrinology (1982) 0.84
Studies on soluble and mitochondrial tyrosine aminotransferase: evidence for a physical change in the cytosol enzyme during induction. Biochem Biophys Res Commun (1969) 0.83
Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils. Clin Exp Immunol (2000) 0.83
Identity of corticosteroid binder I with the macromolecule binding 3-methylcholanthrene in liver cytosol in vivo. Cancer Res (1971) 0.83
Liver cytosol corticosteroid binder IB, a new binding protein. J Biol Chem (1975) 0.83