PubRank

D Marmé

Author PubWeight™ 108.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J Biol Chem 1993 7.16
2 Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996 5.31
3 Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature 1993 5.23
4 Calmodulin activation of plant microsomal Ca uptake. Proc Natl Acad Sci U S A 1980 2.94
5 Red Light-enhanced Phytochrome Pelletability: Re-examination and Further Characterization. Plant Physiol 1976 2.77
6 Turnover of phytochrome in pumpkin cotyledons. Plant Physiol 1973 2.58
7 ATP-dependent Ca uptake into plant membrane vesicles. Proc Natl Acad Sci U S A 1978 2.24
8 Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease. Cancer 1999 2.17
9 Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res 1996 2.10
10 Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 1994 2.01
11 De novo synthesis of phytochrome in pumpkin hooks. Plant Physiol 1973 1.89
12 Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem Biophys Res Commun 1995 1.87
13 Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res 2000 1.79
14 Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis. Arthritis Rheum 2001 1.74
15 In Vivo Properties of Membrane-bound Phytochrome. Plant Physiol 1974 1.73
16 Particle-bound phytochrome from maize and pumpkin. Nat New Biol 1973 1.72
17 Activation of plant quinate:NAD 3-oxidoreductase by Ca and calmodulin. Proc Natl Acad Sci U S A 1983 1.70
18 Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem 1995 1.65
19 AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun 1992 1.60
20 Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials. Ann Oncol 2005 1.57
21 Specific binding of the calcium antagonist [3H]verapamil to membrane fractions from plants. J Biol Chem 1985 1.54
22 Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A 1993 1.44
23 Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression. Oncogene 1997 1.44
24 Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. J Biol Chem 1997 1.41
25 Oncogenes as inducers of tumor angiogenesis. Cancer Metastasis Rev 1995 1.39
26 Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 1995 1.26
27 Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors. Angiogenesis 2001 1.25
28 Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C. Cancer Res 1992 1.24
29 Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells. J Cell Biochem 1994 1.18
30 Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 1999 1.17
31 VEGF-mediated tumour angiogenesis: a new target for cancer therapy. Curr Opin Biotechnol 1995 1.16
32 Human chorionic gonadotropin-dependent expression of vascular endothelial growth factor/vascular permeability factor in human granulosa cells: importance in ovarian hyperstimulation syndrome. J Clin Endocrinol Metab 1995 1.15
33 Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res 1997 1.10
34 Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood. Angiogenesis 2001 1.08
35 Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes. Eur J Biochem 1993 1.03
36 Sequence of human protein kinase C alpha. Nucleic Acids Res 1990 1.01
37 Binding properties of the plant photoreceptor phytochrome to membranes. J Supramol Struct 1974 0.98
38 Purification and identification of calmodulin from Neurospora crassa. FEBS Lett 1981 0.98
39 Expression of the vascular endothelial growth factor gene is inhibited by p73. Oncogene 2000 0.97
40 Basic fibroblast growth factor modulates the mitogenic potency of the platelet-derived growth factor (PDGF) isoforms by specific upregulation of the PDGF alpha receptor in vascular smooth muscle cells. J Biol Chem 1992 0.97
41 Vascular endothelial growth factor (VEGF) mRNA expression in human tumor models of different histologies. Ann Oncol 1995 0.97
42 Myosin heavy chain kinase inactivated by Ca2+/calmodulin from aggregating cells of Dictyostelium discoideum. EMBO J 1983 0.97
43 Calmodulin from neurospora crassa. General properties and conformational changes. J Biol Chem 1982 0.96
44 Expression of biologically active isoforms of the tumor angiogenesis factor VEGF in Escherichia coli. Biochem Biophys Res Commun 1996 0.95
45 Active interaction of human A375 melanoma cells with the lymphatics in vivo. Histochem Cell Biol 2000 0.95
46 Detection and quantification of vascular endothelial growth factor/vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis? Neurosurgery 1994 0.92
47 VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane. Dev Biol 1996 0.92
48 An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells. Proc Natl Acad Sci U S A 1998 0.92
49 Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 and 14q24-q31 regions, respectively. Genomics 1996 0.89
50 Inducible overexpression of human protein kinase C alpha in NIH 3T3 fibroblasts results in growth abnormalities. Cell Signal 1992 0.88
51 Pertussis toxin inhibits the angiotensin II and serotonin-induced rise of free cytoplasmic calcium in cultured smooth muscle cells from rat aorta. FEBS Lett 1987 0.88
52 The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities. Cancer Metastasis Rev 1998 0.87
53 Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells. Eur J Biochem 1993 0.86
54 Activation of purified human protein kinase C alpha and beta I isoenzymes in vitro by Ca2+, phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate. Biochem J 1993 0.86
55 Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro. Biochim Biophys Acta 2000 0.85
56 High-efficiency expression of rat protein kinase C-gamma in baculovirus-infected insect cells. FEBS Lett 1990 0.84
57 The alpha-helical domain near the amino terminus is essential for dimerization of vascular endothelial growth factor. J Biol Chem 1998 0.83
58 A Ca2+, Calmodulin-dependent NAD kinase from corn is located in the outer mitochondrial membrane. J Biol Chem 1984 0.83
59 3,4,5-Triiodobenzoic acid affects [3H]verapamil binding to plant and animal membrane fractions and smooth muscle contraction. Biochem Biophys Res Commun 1986 0.82
60 Anti-microtubular herbicides and fungicides affect Ca(2+) transport in plant mitochondria. Planta 1980 0.82
61 Inducible expression of human phospholipase C-gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts. Eur J Biochem 1992 0.81
62 Calmodulin-dependent and independent NAD kinase activities from cytoplasmic and chloroplastic fractions of spinach (Spinacia oleracea L.). Plant Cell Rep 1982 0.80
63 Synthetic diacylglycerols induce a rise of quin2-detectable free intracellular calcium in human platelets. FEBS Lett 1987 0.80
64 Phorbol 12,13-dibutyrate-induced contraction of isolated rabbit vascular smooth muscle. Eur J Pharmacol 1987 0.80
65 Ca(2+) transport in mitochondrial and microsomal fractions from higher plants. Planta 1980 0.79
66 Calmodulin-stimulated cyclic nucleotide phosphodiesterase from Neurospora crassa. Biochim Biophys Acta 1983 0.79
67 Stereoselective inhibition of calmodulin-dependent cAMP phosphodiesterase from bovine heart by (+)- and (-)-nimodipine. Naunyn Schmiedebergs Arch Pharmacol 1987 0.79
68 Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo. Carcinogenesis 1995 0.78
69 Phytochrome: First-order phototransformation kinetics in vivo. Planta 1973 0.78
70 Angiotensin II mediates intracellular signalling in vascular smooth muscle cells by activation of tyrosine-specific protein kinases and c-raf-1. Biochem Biophys Res Commun 1993 0.78
71 Pertussis toxin inhibits angiotensin II-mediated phosphatidylinositol breakdown and ADP-ribosylates a 40 Kd protein in cultured smooth muscle cells. Biochem Biophys Res Commun 1988 0.77
72 Cloning and functional analysis of the hematopoietic cell-specific phospholipase C(gamma)2 promoter. FEBS Lett 1996 0.77
73 Over-expression of human phospholipase C-gamma 2 enhances platelet-derived growth factor-induced mobilization of intracellular Ca2+ and the release of arachidonic acid and prostaglandins in NIH 3T3 fibroblasts. FEBS Lett 1992 0.77
74 Identification of calmodulin in the green alga Mougeotia and its possible function in chloroplast reorientational movement. Planta 1984 0.77
75 Over-expression of protein kinase C-alpha enhances platelet-derived growth factor- and phorbol ester- but not calcium ionophore-induced formation of prostaglandins in NIH 3T3 fibroblasts. FEBS Lett 1993 0.76
76 The effect of calmodulin and far-red light on the kinetic properties of the mitochondrial and microsomal calcium-ion transport system from corn. Planta 1983 0.76
77 Novel indolocarbazole protein kinase C inhibitors prevent reactivation of HIV-1 in latently infected cells. Antiviral Res 1993 0.76
78 Herbicides and fungicides stimulate Ca2+ efflux from rat liver mitochondria. FEBS Lett 1981 0.76
79 Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application. Dev Dyn 1995 0.76
80 Calcium-binding and its effect on circular dichroism of plant calmodulin. Planta 1985 0.76
81 Stereospecific inhibition of 5-HT-induced increase of intracellular free calcium by (+)- and (-)-desmethoxyverapamil in human platelets. Br J Pharmacol 1986 0.75
82 Induction of the blood-brain barrier marker neurothelin/HT7 in endothelial cells by a variety of tumors in chick embryos. Histochem Cell Biol 2000 0.75
83 An endogenous membrane-bound protein inhibits the phosphorylation of the L-type calcium channel by the cAMP-dependent protein kinase. Biochem Biophys Res Commun 1992 0.75
84 Characterization and partial purification of a membrane protein from rabbit skeletal muscle which inhibits the cAMP-dependent protein kinase. Biochem Biophys Res Commun 1992 0.75
85 Biochemical characterization of binding sites for dihydropyridine and omega-conotoxin in brain of adult chicken. Biochem Biophys Res Commun 1992 0.75
86 On the phytochrome phototransformation kinetics in mustard seedlings. Planta 1971 0.75
87 [Calcium. Molecular mechanisms of cellular function]. Naturwissenschaften 1985 0.75
88 The fungicide chloraniformethan and the herbicide dichlofopmethyl affect calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain. FEBS Lett 1983 0.75
89 Calmodulin-activated plant microsomal Ca2+ uptake and purification of plant NAD kinase and other proteins by calmodulin-Sepharose chromatography. Ann N Y Acad Sci 1980 0.75
90 Dihydropyridine binding of the calcium channel complex from skeletal muscle is modulated by subunit interaction. Cell Signal 1992 0.75
91 Protein phosphorylation and its regulation by calcium and calmodulin in membrane fractions from zucchini hypocotyls. Planta 1983 0.75
92 The demonstrationin vivo of more than one form ofP fr. Planta 1971 0.75
93 Microsomal CA2+ uptake in human platelets is stimulated by calmodulin. Thromb Res 1986 0.75
94 [Are there alternative forms of therapy in breast carcinoma? Status and perspectives for the treatment of metastasized breast carcinoma]. Praxis (Bern 1994) 1995 0.75
95 [Are there alternative therapeutic methods for breast carcinoma? Status and perspectives for treatment of metastatic breast carcinoma]. Gynakologe 1994 0.75