Published in J Biol Chem on May 05, 1993
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain. EMBO J (1998) 4.14
PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity. Nat Struct Mol Biol (2009) 3.37
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A (1998) 3.18
A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat Chem Biol (2009) 3.15
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. J Physiol (2006) 2.34
A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol Cell Biol (2005) 2.16
Activation of protein kinase C triggers its ubiquitination and degradation. Mol Cell Biol (1998) 2.15
NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc Natl Acad Sci U S A (2000) 2.13
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem (2010) 2.06
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. J Clin Invest (2006) 2.00
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells. J Cell Biol (1999) 1.98
Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A (2000) 1.94
Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells. Am J Physiol Cell Physiol (2011) 1.87
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol Cell Biol (2002) 1.85
Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway. Dev Cell (2014) 1.79
Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes. EMBO J (1998) 1.76
Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone. J Biol Chem (2008) 1.74
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus. EMBO J (2002) 1.72
Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2. Biochem Biophys Res Commun (2008) 1.71
Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell (2006) 1.67
A decrease in membrane tension precedes successful cell-membrane repair. Mol Biol Cell (2000) 1.64
Nonmuscle myosin IIA and IIB have distinct functions in the exocytosis-dependent process of cell membrane repair. Mol Biol Cell (2003) 1.59
Reconstitution of protein kinase C-induced contractile Ca2+ sensitization in triton X-100-demembranated rabbit arterial smooth muscle. J Physiol (1999) 1.59
A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Mol Cancer Ther (2010) 1.58
PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J (2004) 1.51
The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops. PLoS Biol (2013) 1.50
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism. Am J Pathol (2005) 1.50
Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton. J Cell Biol (1999) 1.46
Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proc Natl Acad Sci U S A (2005) 1.45
The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers. Proc Natl Acad Sci U S A (2001) 1.44
Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes. Mol Cell Biol (2003) 1.44
From calcium to NF-kappa B signaling pathways in neurons. Mol Cell Biol (2003) 1.38
STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nat Immunol (2011) 1.37
Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. J Clin Invest (2005) 1.36
The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells. Mol Biol Cell (2000) 1.35
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol (2006) 1.32
Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes. Mol Cell Biol (2004) 1.31
TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells. Am J Physiol Gastrointest Liver Physiol (2008) 1.31
Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis. J Leukoc Biol (2005) 1.31
Activation of the TRPV4 ion channel is enhanced by phosphorylation. J Biol Chem (2009) 1.30
Tumor promotion by depleting cells of protein kinase C delta. Mol Cell Biol (1997) 1.30
Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle. J Physiol (1997) 1.29
Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis. Mol Biol Cell (2005) 1.29
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
Protein kinase C pharmacology: refining the toolbox. Biochem J (2013) 1.27
Fibroblast growth factor-specific modulation of cellular response by syndecan-4. J Cell Biol (2002) 1.26
Protein kinase D as a potential new target for cancer therapy. Biochim Biophys Acta (2010) 1.25
PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor. EMBO J (1999) 1.23
Angiotensin II inhibits rat arterial KATP channels by inhibiting steady-state protein kinase A activity and activating protein kinase Ce. J Physiol (2001) 1.23
PKCepsilon, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells. J Cell Biol (1999) 1.23
Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U S A (2004) 1.22
Self-renewal versus lineage commitment of embryonic stem cells: protein kinase C signaling shifts the balance. Stem Cells (2011) 1.22
Role of protein kinase C betaII in influenza virus entry via late endosomes. J Virol (2003) 1.22
Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. BMC Chem Biol (2010) 1.20
Activation of the VEGFR1 chromatin domain: an angiogenic signal-ETS1/HIF-2alpha regulatory axis. J Biol Chem (2008) 1.20
Requirement of protein kinase C zeta for stimulation of protein synthesis by insulin. Mol Cell Biol (1997) 1.20
Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation. Biochem J (2009) 1.19
Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity. Proc Natl Acad Sci U S A (2011) 1.18
alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. Biochem J (1998) 1.16
Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B. Mol Biol Cell (2010) 1.14
Role of protein kinase D signaling in pancreatic cancer. Biochem Pharmacol (2010) 1.14
VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation. J Immunol (2006) 1.13
Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J Biol Chem (2010) 1.13
Phosphorylation of claudin-4 by PKCepsilon regulates tight junction barrier function in ovarian cancer cells. Exp Cell Res (2007) 1.12
Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2. Proc Natl Acad Sci U S A (2012) 1.12
Protein kinase C epsilon contributes to basal and sensitizing responses of TRPV1 to capsaicin in rat dorsal root ganglion neurons. Eur J Neurosci (2008) 1.12
Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility. BMC Cell Biol (2009) 1.11
P2Y6 nucleotide receptor activates PKC to protect 1321N1 astrocytoma cells against tumor necrosis factor-induced apoptosis. Cell Mol Neurobiol (2003) 1.11
Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter. Mol Cell Biol (2002) 1.11
PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating. Proc Natl Acad Sci U S A (2006) 1.11
Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor. Mol Cell Biol (1999) 1.10
Polyinosinic:polycytidylic acid induces protein kinase D-dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells. J Allergy Clin Immunol (2011) 1.10
Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid. J Biol Chem (2009) 1.10
Protein kinase C-dependent control of Bcl-x alternative splicing. Mol Cell Biol (2007) 1.10
Protein kinase C and cancer: what we know and what we do not. Oncogene (2013) 1.09
Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells. Am J Physiol Cell Physiol (2010) 1.09
VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1B. J Immunol (2007) 1.09
CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma. J Clin Invest (2012) 1.09
Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. PLoS One (2010) 1.09
PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. Am J Physiol Heart Circ Physiol (2011) 1.09
RhoA/ROCK pathway is the major molecular determinant of basal tone in intact human internal anal sphincter. Am J Physiol Gastrointest Liver Physiol (2012) 1.09
Domain-based biosensor assay to screen for epidermal growth factor receptor modulators in live cells. Assay Drug Dev Technol (2012) 1.09
Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA. Am J Physiol Lung Cell Mol Physiol (2009) 1.08
Altered properties of volume-sensitive osmolyte and anion channels (VSOACs) and membrane protein expression in cardiac and smooth muscle myocytes from Clcn3-/- mice. J Physiol (2004) 1.08
Atypical protein kinase Cι as a human oncogene and therapeutic target. Biochem Pharmacol (2013) 1.08
Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release. Front Immunol (2013) 1.07
Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells. Biochem J (1995) 1.06
Eucapnic intermittent hypoxia augments endothelin-1 vasoconstriction in rats: role of PKCdelta. Am J Physiol Heart Circ Physiol (2007) 1.05
P2X7 receptors stimulate AKT phosphorylation in astrocytes. Br J Pharmacol (2004) 1.05
Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition. J Cell Physiol (2010) 1.05
Intracellular sigma1 receptor modulates phospholipase C and protein kinase C activities in the brainstem. Proc Natl Acad Sci U S A (1999) 1.05
Protein kinases and addiction. Ann N Y Acad Sci (2008) 1.05
Air bubble contact with endothelial cells causes a calcium-independent loss in mitochondrial membrane potential. PLoS One (2012) 1.03
The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation. Mol Cell Biol (2010) 1.03
Role of HuR and p38MAPK in ultraviolet B-induced post-transcriptional regulation of COX-2 expression in the human keratinocyte cell line HaCaT. J Biol Chem (2009) 1.03
Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy. J Biol Chem (2011) 1.03
Tight-junction protein zonula occludens 2 is a target of phosphorylation by protein kinase C. Biochem J (2001) 1.03
Comparison of regulated passive membrane conductance in action potential-firing fast- and slow-twitch muscle. J Gen Physiol (2009) 1.03
Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes. Bacteriol Rev (1974) 7.49
Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol Rev (1999) 7.20
Mechanism of action and development of resistance to a new amidino penicillin. J Bacteriol (1974) 5.47
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood (1996) 5.31
Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature (1993) 5.23
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion? Nat Med (1996) 5.09
Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature (1995) 4.20
Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP. Nature (1999) 3.99
Multiple penicillin-binding components in Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Escherichia coli. J Biol Chem (1972) 3.32
Penicillin-sensitive enzymes and penicillin-binding components in bacterial cells. Ann N Y Acad Sci (1974) 3.16
Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester. Cell (1995) 3.08
Specific binding of phorbol ester tumor promoters. Proc Natl Acad Sci U S A (1980) 3.07
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J (1998) 3.06
Calmodulin activation of plant microsomal Ca uptake. Proc Natl Acad Sci U S A (1980) 2.94
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proc Natl Acad Sci U S A (2000) 2.87
Five penicillin-binding components occur in Bacillus subtilis membranes. J Biol Chem (1972) 2.81
Inactivation of D-alanine carboxypeptidase by penicillins and cephalosporins is not lethal in Bacillus subtilis. Proc Natl Acad Sci U S A (1971) 2.80
Red Light-enhanced Phytochrome Pelletability: Re-examination and Further Characterization. Plant Physiol (1976) 2.77
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. J Biol Chem (1993) 2.62
Regulation of cell apoptosis by protein kinase c delta. Apoptosis (2003) 2.60
Turnover of phytochrome in pumpkin cotyledons. Plant Physiol (1973) 2.58
Analysis of the native quaternary structure of vanilloid receptor 1. J Biol Chem (2001) 2.55
RasGRP links T-cell receptor signaling to Ras. Blood (2000) 2.46
Mx proteins: mediators of innate resistance to RNA viruses. Rev Sci Tech (1998) 2.40
New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J (1999) 2.39
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest (1997) 2.32
Isolation by covalent affinity chromatography of the penicillin-binding components from membranes of Bacillus subtilis. Proc Natl Acad Sci U S A (1972) 2.28
Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein. Mol Cell Biol (2000) 2.27
ATP-dependent Ca uptake into plant membrane vesicles. Proc Natl Acad Sci U S A (1978) 2.24
Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol. Proc Natl Acad Sci U S A (1983) 2.23
How penicillin kills bacteria: progress and problems. Proc R Soc Lond B Biol Sci (1971) 2.21
Mechanism of inhibition of Raf-1 by protein kinase A. Mol Cell Biol (1994) 2.18
Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease. Cancer (1999) 2.17
The effect of phorbol diesters on chicken embryo fibroblasts. Cancer Res (1977) 2.14
Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res (1996) 2.10
Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene (1994) 2.01
Taxonomy and function of C1 protein kinase C homology domains. Protein Sci (1997) 1.98
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper. Neuroscience (1989) 1.94
Different pathways mediate virus inducibility of the human IFN-alpha 1 and IFN-beta genes. Cell (1990) 1.91
De novo synthesis of phytochrome in pumpkin hooks. Plant Physiol (1973) 1.89
Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes. J Biol Chem (1995) 1.87
Raf-1-associated protein phosphatase 2A as a positive regulator of kinase activation. J Biol Chem (2000) 1.87
Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem Biophys Res Commun (1995) 1.87
The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures. FEBS Lett (1999) 1.81
A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1. J Med Chem (1992) 1.80
Inhibition of bunyaviruses, phleboviruses, and hantaviruses by human MxA protein. J Virol (1996) 1.76
Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis. Arthritis Rheum (2001) 1.74
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: part 1. Crit Rev Toxicol (1980) 1.73
In Vivo Properties of Membrane-bound Phytochrome. Plant Physiol (1974) 1.73
Human MxA protein inhibits tick-borne Thogoto virus but not Dhori virus. J Virol (1995) 1.73
Particle-bound phytochrome from maize and pumpkin. Nat New Biol (1973) 1.72
Activation of plant quinate:NAD 3-oxidoreductase by Ca and calmodulin. Proc Natl Acad Sci U S A (1983) 1.70
Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem (1995) 1.65
Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product. Mol Cell Biol (1987) 1.63
A classical bipartite nuclear localization signal on Thogoto and influenza A virus nucleoproteins. Virology (1998) 1.60
Competitive inhibition by diacylglycerol of specific phorbol ester binding. Proc Natl Acad Sci U S A (1984) 1.60
AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor. Biochem Biophys Res Commun (1992) 1.60
Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1. J Biol Chem (2000) 1.59
Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts. J Biol Chem (1994) 1.55
Specific binding of the calcium antagonist [3H]verapamil to membrane fractions from plants. J Biol Chem (1985) 1.54
Tick-borne thogoto virus infection in mice is inhibited by the orthomyxovirus resistance gene product Mx1. J Virol (1995) 1.52
Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta. J Biol Chem (1993) 1.51
Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol Cell Biol (1999) 1.51
Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties. J Biol Chem (1996) 1.49
Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta. J Biol Chem (2000) 1.49
Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products. J Biol Chem (1994) 1.49
Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. Proc Natl Acad Sci U S A (1988) 1.49
Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts. Nature (1976) 1.48
Mechanism of action of the phorbol ester tumor promoters: specific receptors for lipophilic ligands. Biochem Pharmacol (1984) 1.46
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. Carcinogenesis (1987) 1.44
Dominant-negative mutants of human MxA protein: domains in the carboxy-terminal moiety are important for oligomerization and antiviral activity. J Virol (1997) 1.44
Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A (1993) 1.44
Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression. Oncogene (1997) 1.44
Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat Med (1998) 1.42
Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1. J Biol Chem (1997) 1.41
Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Mol Pharmacol (1993) 1.40
Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs. Proc Natl Acad Sci U S A (1986) 1.39
Protective role of interferon-induced Mx GTPases against influenza viruses. Rev Sci Tech (2009) 1.39
Oncogenes as inducers of tumor angiogenesis. Cancer Metastasis Rev (1995) 1.39
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters, part 2. Crit Rev Toxicol (1981) 1.38
Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein. J Biol Chem (1999) 1.36
Tyrosine phosphorylation of protein kinase C-delta in response to its activation. J Biol Chem (1994) 1.36
Specific binding of phorbol ester tumor promoters to mouse skin. Cell (1980) 1.34
Enzymic synthesis of isoflavones. Eur J Biochem (1986) 1.33
Residues in the second cysteine-rich region of protein kinase C delta relevant to phorbol ester binding as revealed by site-directed mutagenesis. J Biol Chem (1995) 1.33
Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation. J Neurosci (2001) 1.32