Published in J Exp Med on February 01, 1994
Late developmental plasticity in the T helper 17 lineage. Immunity (2009) 8.81
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med (1996) 6.73
Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol (2009) 4.76
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity (2008) 4.67
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med (2003) 4.39
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med (2004) 3.83
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect Immun (1998) 3.80
IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest (2004) 3.69
Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology (2011) 3.52
Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med (1996) 3.36
Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J Exp Med (1996) 2.97
The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. Nat Immunol (2009) 2.73
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol (1997) 2.71
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med (1994) 2.70
CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice. Am J Pathol (2003) 2.70
Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis. J Exp Med (2002) 2.60
Tumour necrosis factor and Crohn's disease. Gut (1997) 2.27
An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J Exp Med (1998) 2.26
Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice. J Exp Med (1997) 2.21
Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain. Gut (1998) 2.20
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn's disease. J Clin Invest (2001) 1.96
Influence of intestinal bacteria on induction of regulatory T cells: lessons from a transfer model of colitis. Gut (2005) 1.95
Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol Rev (2008) 1.88
Altered immune responses in interleukin 10 transgenic mice. J Exp Med (1997) 1.85
The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease. J Immunol (2008) 1.75
Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea. J Clin Invest (2000) 1.66
The development and function of regulatory T cells. Cell Mol Life Sci (2009) 1.66
An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc Natl Acad Sci U S A (2003) 1.65
Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice. J Exp Med (1996) 1.61
Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam. Proc Natl Acad Sci U S A (1995) 1.59
Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology. J Exp Med (2011) 1.55
Experimental inflammatory bowel disease: insights into the host-microbiota dialog. Immunity (2011) 1.53
Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice. Am J Pathol (2002) 1.50
Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3). J Allergy Clin Immunol (2014) 1.49
Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. J Clin Invest (1997) 1.44
CCR4-dependent regulatory T cell function in inflammatory bowel disease. J Exp Med (2007) 1.41
Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation. J Clin Invest (2003) 1.40
MHC class II expression restricted to CD8alpha+ and CD11b+ dendritic cells is sufficient for control of Leishmania major. J Exp Med (2004) 1.40
Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease. Gut (2002) 1.40
Emergent autoimmunity in graft-versus-host disease. Blood (2005) 1.37
Unique role of CD4+CD62L+ regulatory T cells in the control of autoimmune diabetes in T cell receptor transgenic mice. Proc Natl Acad Sci U S A (2004) 1.32
Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am J Pathol (2006) 1.27
Moving to tolerance: clinical application of T regulatory cells. Semin Immunol (2011) 1.25
Intestinal microbiota: shaping local and systemic immune responses. Semin Immunol (2011) 1.21
Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers. Immunology (2012) 1.20
CD8+CD28- regulatory T lymphocytes prevent experimental inflammatory bowel disease in mice. Gastroenterology (2006) 1.20
CD4+ T-helper-cell responses in mice with low-level Candida albicans infection. Infect Immun (1996) 1.18
Interleukin-23 and T helper 17-type responses in intestinal inflammation: from cytokines to T-cell plasticity. Immunology (2011) 1.17
Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells. J Exp Med (2014) 1.16
Protective and pathologic immune responses in human tegumentary leishmaniasis. Front Immunol (2012) 1.13
Oral tolerance. J Clin Immunol (1998) 1.11
Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis. Proc Natl Acad Sci U S A (2015) 1.09
Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' disease. Infect Immun (1999) 1.08
Regulatory T-cell stability and plasticity in mucosal and systemic immune systems. Mucosal Immunol (2010) 1.06
CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation. Gut (2005) 1.06
PKC-θ function at the immunological synapse: prospects for therapeutic targeting. Trends Immunol (2011) 1.06
An imbalance of esophageal effector and regulatory T cell subsets in experimental eosinophilic esophagitis in mice. Am J Physiol Gastrointest Liver Physiol (2009) 1.05
Mechanisms and functional implications of intestinal barrier defects. Dig Dis (2009) 1.04
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells. J Exp Med (2005) 1.04
Role of transcription factor T-bet expression by CD4+ cells in gastritis due to Helicobacter pylori in mice. Infect Immun (2006) 1.03
Tolerance, suppression and the fetal allograft. J Mol Med (Berl) (2004) 1.02
Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease. J Clin Invest (1997) 1.02
CD4 antibody treatment in patients with active Crohn's disease: a phase 1 dose finding study. Gut (1997) 1.01
beta7 Integrin expression is not required for the localization of T cells to the intestine and colitis pathogenesis. Clin Exp Immunol (2002) 1.01
Abnormalities of CD4 T cell subpopulations in ANCA-associated vasculitis. Clin Exp Immunol (2005) 1.00
Interleukin-12 therapy reduces the number of immune cells and pathology in lungs of mice infected with Mycobacterium tuberculosis. Infect Immun (2004) 0.97
Antibody-mediated targeting of CD45 isoforms: a novel immunotherapeutic strategy. Proc Natl Acad Sci U S A (1998) 0.94
Leukocyte adhesion molecules in animal models of inflammatory bowel disease. Inflamm Bowel Dis (2008) 0.94
Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function. Mucosal Immunol (2013) 0.93
Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells. Proc Natl Acad Sci U S A (2009) 0.93
Phenotypic changes in T cell populations during the reactivation of tuberculosis in mice. Clin Exp Immunol (1998) 0.92
Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses. Infect Immun (1994) 0.92
Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice. Gastroenterology (2013) 0.91
A murine model of appendicitis and the impact of inflammation on appendiceal lymphocyte constituents. Clin Exp Immunol (2007) 0.91
Extra-adrenal glucocorticoid synthesis in the intestinal epithelium: more than a drop in the ocean? Semin Immunopathol (2009) 0.90
Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells. J Immunol (2011) 0.90
Raf signaling but not the ERK effector SAP-1 is required for regulatory T cell development. J Immunol (2007) 0.89
A novel role for KLF14 in T regulatory cell differentiation. Cell Mol Gastroenterol Hepatol (2015) 0.88
Regulatory T cells and immune tolerance in the intestine. Cold Spring Harb Perspect Biol (2013) 0.88
Glucocorticoid-induced tumor necrosis factor receptor family-related protein regulates CD4(+)T cell-mediated colitis in mice. Gastroenterology (2011) 0.88
Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease. Dig Dis Sci (2008) 0.86
Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med (2013) 0.86
Does CD4+CD25+foxp3+ cell (Treg) and IL-10 profile determine susceptibility to immune reconstitution inflammatory syndrome (IRIS) in HIV disease? J Inflamm (Lond) (2008) 0.86
Nucleotide-binding oligomerization domain 2 signaling promotes hyperresponsive macrophages and colitis in IL-10-deficient mice. J Immunol (2013) 0.86
Cyclin-dependent kinase 2 controls peripheral immune tolerance. J Immunol (2012) 0.86
Getting to the guts of immune regulation. Immunology (2002) 0.85
Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice. PLoS One (2012) 0.85
Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer. Inflamm Bowel Dis (2014) 0.84
T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine. Nat Commun (2016) 0.84
In vitro activated CD4+ T cells from interferon-gamma (IFN-gamma)-deficient mice induce intestinal inflammation in immunodeficient hosts. Clin Exp Immunol (1999) 0.84
Tumour necrosis factor-alpha (TNF-alpha) transcription and translation in the CD4+ T cell-transplanted scid mouse model of colitis. Clin Exp Immunol (1999) 0.84
Analysis of naïve lung CD4 T cells provides evidence of functional lung to lymph node migration. Proc Natl Acad Sci U S A (2013) 0.84
Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects. J Exp Med (2016) 0.84
Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expression. Blood (2008) 0.83
The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells. Immunity (2014) 0.83
Epistemology of the origin of cancer: a new paradigm. BMC Cancer (2014) 0.83
Regulatory T cells use "Itch" to control asthma. J Clin Invest (2013) 0.82
A protective role for human IL-10-expressing CD4+ T cells in colitis. J Immunol (2012) 0.82
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 22.57
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature (1992) 16.46
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
A severe combined immunodeficiency mutation in the mouse. Nature (1983) 13.99
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell (1993) 11.95
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A (1993) 10.82
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol (1993) 9.97
Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development. Immunol Rev (1982) 6.43
Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol (1988) 5.80
Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis. Proc Natl Acad Sci U S A (1991) 4.95
Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev (1992) 3.30
OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset. J Exp Med (1990) 3.23
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential. J Exp Med (1993) 3.10
Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J (1991) 2.97
Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo. Immunol Rev (1991) 2.85
MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen. J Exp Med (1983) 2.72
Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J Immunol (1991) 2.70
Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells. J Immunol (1990) 2.41
A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol (1989) 2.33
Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc Natl Acad Sci U S A (1989) 2.15
IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures. J Immunol (1990) 2.05
Functional heterogeneity of CD4+ T cells in leishmaniasis. Immunol Today (1989) 1.97
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur J Immunol (1993) 1.92
Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells. J Exp Med (1989) 1.91
Long-term CD4+ memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol (1992) 1.72
Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement. Proc Natl Acad Sci U S A (1993) 1.71
Development of rat anti-mouse interleukin 3 monoclonal antibodies which neutralize bioactivity in vitro. J Immunol (1988) 1.55
Interleukin-4 but not gamma interferon production correlates with the severity of murine cutaneous leishmaniasis. Infect Immun (1993) 1.49
Higher frequency of Leishmania major-specific L3T4+ T cells in susceptible BALB/c as compared with resistant CBA mice. J Immunol (1986) 1.45
Memory CD4+ T cells in man form two distinct subpopulations, defined by their expression of isoforms of the leucocyte common antigen, CD45. Immunology (1990) 1.43
Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells. Int Immunol (1991) 1.35
Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection. Eur J Immunol (1993) 1.34
Coexistence of antigen-specific TH1 and TH2 cells in genetically susceptible BALB/c mice infected with Leishmania major. Immunobiology (1989) 1.14
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 25.63
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med (1989) 11.36
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med (1999) 10.67
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol (1993) 9.97
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity (1994) 9.63
Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol (1990) 7.93
Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med (1988) 7.02
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med (1996) 6.73
Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development. Immunol Rev (1982) 6.43
B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol (1986) 6.16
A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma. J Immunol (1986) 6.03
Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv Immunol (1989) 5.92
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature (1988) 5.56
IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. J Immunol (1988) 5.12
Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu Rev Immunol (1992) 4.92
B220: a B cell-specific member of th T200 glycoprotein family. Nature (1981) 4.65
IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol (1992) 4.43
The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J Immunol (1988) 4.38
An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science (1992) 3.78
T-cell and mast cell lines respond to B-cell stimulatory factor 1. Proc Natl Acad Sci U S A (1986) 3.56
Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunol Rev (1989) 3.21
A monoclonal antibody that recognizes B cells and B cell precursors in mice. J Exp Med (1981) 3.13
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus. J Clin Invest (1994) 3.12
CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro. Eur J Immunol (1998) 2.89
Abnormalities induced by the mutant gene Ipr: expansion of a unique lymphocyte subset. J Immunol (1982) 2.78
Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells. Science (1995) 2.74
Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5. Proc Natl Acad Sci U S A (1987) 2.55
Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells. Proc Natl Acad Sci U S A (1988) 2.37
Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proc Natl Acad Sci U S A (1990) 2.37
Restoration of IFN-gamma production and lymphocyte proliferation in visceral leishmaniasis. J Immunol (1994) 2.25
T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol (2000) 2.22
Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production. J Exp Med (1990) 2.09
Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity (1999) 2.09
Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures. J Exp Med (1988) 2.08
Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol Today (1993) 2.08
Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells. Am J Pathol (1996) 2.03
Chain elongation rate of messenger and polypeptides in slowly growing Escherichia coli. J Mol Biol (1971) 1.96
Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. J Immunol (1982) 1.95
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur J Immunol (1993) 1.92
A unique series of lymphomas related to the Ly-1+ lineage of B lymphocyte differentiation. J Immunol (1984) 1.89
Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse. J Immunol (1990) 1.88
Evidence that development of severe cardiomyopathy in human Chagas' disease is due to a Th1-specific immune response. Infect Immun (2003) 1.81
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur J Immunol (1993) 1.75
Detection of individual mouse splenic T cells producing IFN-gamma and IL-5 using the enzyme-linked immunospot (ELISPOT) assay. J Immunol Methods (1990) 1.74
Mechanism for transforming growth factor beta and IL-2 enhancement of IgA expression in lipopolysaccharide-stimulated B cell cultures. J Immunol (1990) 1.71
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells. J Immunol (1999) 1.70
IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J Immunol (1995) 1.68
Analysis of Th1 and Th2 cells in murine gut-associated tissues. Frequencies of CD4+ and CD8+ T cells that secrete IFN-gamma and IL-5. J Immunol (1990) 1.67
CD4+ T-cells in the regulation of inflammatory responses in the intestine. Res Immunol (1998) 1.66
Modulation of murine macrophage function by IL-13. J Immunol (1993) 1.66
The class of surface immunoglobulin on virgin and memory B lymphocytes. J Immunol (1977) 1.65
Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection. Exp Parasitol (1996) 1.62
Separation of events mediating B cell proliferation and Ig production by using T cell membranes and lymphokines. J Immunol (1990) 1.60
Analysis of neoplasms induced by Cas-Br-M MuLV tumor extracts. J Immunol (1986) 1.58
Down-regulation of Th1 type of response in early human American cutaneous leishmaniasis. J Infect Dis (1999) 1.53
Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci U S A (1994) 1.53
Allergen-specific T cell responses to immunotherapy monitored by CD154 and intracellular cytokine expression. Clin Exp Allergy (2010) 1.48
The induction of a protective response in Leishmania major-infected BALB/c mice with anti-CD40 mAb. Eur J Immunol (1998) 1.46
Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection. J Immunol (1995) 1.46
Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype. J Immunol (1994) 1.43
A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE. J Immunol (1992) 1.41
cDNA clones encoding IgE-binding factors from a rat-mouse T-cell hybridoma. Proc Natl Acad Sci U S A (1985) 1.41
A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL-4-secreting cells. J Immunol (1994) 1.41
Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity (1997) 1.38
Induction of a Th2 population from a polarized Leishmania-specific Th1 population by in vitro culture with IL-4. J Immunol (1995) 1.38
The effects of IL-4 and IL-5 on the IgA response by murine Peyer's patch B cell subpopulations. J Immunol (1988) 1.34
Reconstitution of C.B-17 scid mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection. Eur J Immunol (1993) 1.34
Urban transmission of Chagas disease in Cochabamba, Bolivia. Mem Inst Oswaldo Cruz (2008) 1.31
Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching. Proc Natl Acad Sci U S A (1990) 1.31
Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy. J Immunol (1997) 1.30
Lungkine, a novel CXC chemokine, specifically expressed by lung bronchoepithelial cells. J Immunol (1999) 1.29
Interleukin-12 restores interferon-gamma production and cytotoxic responses in visceral leishmaniasis. J Infect Dis (1996) 1.29
Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice. Proc Natl Acad Sci U S A (1998) 1.27
Interleukin-4 and -10 exacerbate candidiasis in mice. Eur J Immunol (1995) 1.27
Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis. J Exp Med (1999) 1.27
A cell-surface antigen shared by B cells and Ly2+ peripheral T cells. Cell Immunol (1982) 1.27
Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. J Immunol (2001) 1.26
A mouse T cell product that preferentially enhances IgA production. II. Physicochemical characterization. J Immunol (1987) 1.26
Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3). J Leukoc Biol (1999) 1.24
Signalling pathways leading to IFN-alpha production in human plasmacytoid dendritic cell and the possible use of agonists or antagonists of TLR7 and TLR9 in clinical indications. J Intern Med (2009) 1.20
Leishmania major: effect of infectious dose on T cell subset development in BALB/c mice. Exp Parasitol (1996) 1.19
Experimental Leishmania major infection in mice: role of IL-10. Parasite Immunol (1999) 1.19
IgE and eosinophil regulation in a murine model of allergic aspergillosis. J Leukoc Biol (1994) 1.19
Particulate Aspergillus fumigatus antigens elicit a TH2 response in BALB/c mice. J Allergy Clin Immunol (1994) 1.15
Gamma interferon is critical for resistance to Theiler's virus-induced demyelination. J Virol (1995) 1.14
Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class I-independent CD4+NK1.1- T cell population. J Immunol (1996) 1.14