Published in Cell Mol Life Sci on April 24, 2009
Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases. Nat Rev Immunol (2010) 3.69
IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol (2010) 3.43
The plasticity and stability of regulatory T cells. Nat Rev Immunol (2013) 2.15
Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen. Am J Transplant (2013) 1.50
Depression and immunity: a role for T cells? Brain Behav Immun (2009) 1.40
Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6. J Leukoc Biol (2010) 1.23
Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity (2011) 1.23
T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine (2014) 1.21
Long term immunologic consequences of experimental stroke and mucosal tolerance. Exp Transl Stroke Med (2009) 1.15
CD4+ T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis. Viruses (2011) 1.07
The T helper type 17/regulatory T cell imbalance in patients with acute Kawasaki disease. Clin Exp Immunol (2010) 0.99
The therapeutic efficacy of human adipose tissue-derived mesenchymal stem cells on experimental autoimmune hearing loss in mice. Immunology (2011) 0.96
Hodgkin disease and the role of the immune system. Pediatr Hematol Oncol (2011) 0.95
Cellular mediators of inflammation: tregs and TH17 cells in gastrointestinal diseases. Mediators Inflamm (2010) 0.94
Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome. Transplantation (2010) 0.94
Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways. J Immunol (2011) 0.93
Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis. PLoS One (2012) 0.91
Expansion of regulatory T cells in aged mice following influenza infection. Mech Ageing Dev (2011) 0.90
Targeting the innate immune system as immunotherapy for acute myeloid leukemia. Front Oncol (2015) 0.89
Aging of the CD4 T Cell Compartment. Open Longev Sci (2012) 0.87
Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells. Mucosal Immunol (2014) 0.87
Phenotypic and functional characterization of a CD4(+) CD25(high) FOXP3(high) regulatory T-cell population in the dog. Immunology (2010) 0.86
Impaired balance of T helper 17/T regulatory cells in carbon tetrachloride-induced liver fibrosis in mice. World J Gastroenterol (2014) 0.86
Functional defect in regulatory T cells in myasthenia gravis. Ann N Y Acad Sci (2012) 0.84
Novel and functional regulatory SNPs in the promoter region of FOXP3 gene in a Gabonese population. Immunogenetics (2011) 0.83
PD-1 regulates extrathymic regulatory T-cell differentiation. Eur J Immunol (2014) 0.83
The role of CARMA1 in T cells. Crit Rev Immunol (2013) 0.81
Mechanisms of T(reg) Suppression: Still a Long Way to Go. Front Immunol (2012) 0.80
Alteration of CD4CD25Foxp3 T cell level in Kawasaki disease. Korean J Pediatr (2011) 0.80
Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity. Sci Rep (2016) 0.80
Elevated Serum Level of IL-35 Associated with the Maintenance of Maternal-Fetal Immune Tolerance in Normal Pregnancy. PLoS One (2015) 0.79
Historical overview of immunological tolerance. Cold Spring Harb Perspect Biol (2012) 0.79
Microbiota and mucosal immunity in amphibians. Front Immunol (2015) 0.78
Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy. Arch Immunol Ther Exp (Warsz) (2010) 0.78
Regulatory T cell in stroke: a new paradigm for immune regulation. Clin Dev Immunol (2013) 0.78
γδ T cells restrain extrathymic development of Foxp3+-inducible regulatory T cells via IFN-γ. Eur J Immunol (2014) 0.78
Immunomodulation by mesenchymal stem cells: Interplay between mesenchymal stem cells and regulatory lymphocytes. World J Stem Cells (2016) 0.78
In vitro effects of meloxicam on the number, Foxp3 expression, production of selected cytokines, and apoptosis of bovine CD25+CD4+ and CD25-CD4+ cells. J Vet Sci (2013) 0.77
Heat shock proteins and regulatory T cells. Autoimmune Dis (2013) 0.77
MSC therapy attenuates obliterative bronchiolitis after murine bone marrow transplant. PLoS One (2014) 0.77
Reciprocal relationship of T regulatory cells and monocytic myeloid-derived suppressor cells in LP-BM5 murine retrovirus-induced immunodeficiency. J Gen Virol (2015) 0.77
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance. Mol Med Rep (2016) 0.75
Heat shock proteins (HSPs) in the homeostasis of regulatory T cells (Tregs). Cent Eur J Immunol (2016) 0.75
The potential role of cell surface complement regulators and circulating CD4+ CD25+ T-cells in the development of autoimmune myasthenia gravis. Electron Physician (2016) 0.75
Targeting Janus tyrosine kinase 3 (JAK3) with an inhibitor induces secretion of TGF-β by CD4+ T cells. Cell Mol Immunol (2012) 0.75
Pathogenetic determinants in Kawasaki disease: the haematological point of view. J Cell Mol Med (2017) 0.75
CD25+CD127+Foxp3- Cells Represent a Major Subpopulation of CD8+ T Cells in the Eye Chambers of Normal Mice. PLoS One (2017) 0.75
Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4(+)CD25(+) regulatory T cells. Neuropsychiatr Dis Treat (2016) 0.75
pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity. J Immunol Res (2017) 0.75
FoxP3(+) T regulatory cells in oral lichen planus and its correlation with the distinct clinical appearance of the lesions. Int J Exp Pathol (2012) 0.75
AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet. J Transl Med (2015) 0.75
Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06. Immunogenetics (2016) 0.75
Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection. J Immunol (2017) 0.75
The function of regulatory T cells at the ocular surface: Review. Ocul Surf (2017) 0.75
CBirTox is a selective antigen-specific agonist of the Treg-IgA-microbiota homeostatic pathway. PLoS One (2017) 0.75
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature (2006) 46.36
Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 40.32
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol (2003) 38.57
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 29.42
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 26.05
IL-17 and Th17 Cells. Annu Rev Immunol (2009) 23.02
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med (2004) 22.96
Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 22.57
An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol (2003) 19.16
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol (2004) 17.40
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 16.28
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity (2000) 15.44
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet (2001) 15.27
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med (2007) 15.17
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol (2005) 13.03
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science (2007) 12.79
CTLA-4 control over Foxp3+ regulatory T cell function. Science (2008) 12.67
Projection of an immunological self shadow within the thymus by the aire protein. Science (2002) 12.15
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol (2001) 12.00
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med (2007) 11.82
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature (2002) 11.79
How regulatory T cells work. Nat Rev Immunol (2008) 11.66
A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol (2005) 11.48
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol (1998) 11.26
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci U S A (2005) 10.89
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci U S A (1993) 10.82
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med (1999) 10.67
IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol (2004) 10.08
Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol (2005) 9.91
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity (2008) 9.82
Retinoic acid imprints gut-homing specificity on T cells. Immunity (2004) 9.76
Foxp3-dependent programme of regulatory T-cell differentiation. Nature (2007) 9.48
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol (2000) 9.15
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med (2004) 8.98
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med (2002) 8.84
Natural versus adaptive regulatory T cells. Nat Rev Immunol (2003) 8.74
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med (1996) 8.54
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med (2004) 8.00
Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol (2007) 7.86
The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature (2007) 7.82
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med (2007) 7.73
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat Immunol (2007) 7.64
Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol (1999) 7.60
Origin of regulatory T cells with known specificity for antigen. Nat Immunol (2002) 7.49
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity (2000) 6.97
FOXP3: of mice and men. Annu Rev Immunol (2006) 6.89
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity (2004) 6.89
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med (2005) 6.87
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med (1996) 6.73
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity (2007) 6.61
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol (2002) 6.60
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol (2008) 6.56
Natural regulatory T cells in infectious disease. Nat Immunol (2005) 6.49
Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells. J Clin Invest (2003) 6.42
Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol (2007) 6.32
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev (2006) 6.08
Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol (2008) 6.01
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med (2003) 6.00
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med (2007) 5.96
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J Immunol (2003) 5.94
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood (2002) 5.72
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res (2001) 5.48
In vivo instruction of suppressor commitment in naive T cells. J Exp Med (2004) 5.47
Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol (2003) 5.47
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol (2007) 5.45
Regulatory T cell development in the absence of functional Foxp3. Nat Immunol (2007) 5.44
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res (1999) 5.41
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity (2002) 5.38
Coordination of early protective immunity to viral infection by regulatory T cells. Science (2008) 5.33
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28
"Infectious" transplantation tolerance. Science (1993) 4.98
Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J Immunol (2002) 4.95
Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol (2007) 4.87
The cellular mechanism of Aire control of T cell tolerance. Immunity (2005) 4.74
Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis. Am J Respir Crit Care Med (2005) 4.72
CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med (2007) 4.66
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature (2005) 4.60
CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J Exp Med (2003) 4.56
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest (2007) 4.44
Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells. J Exp Med (2002) 4.37
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med (2004) 4.35
A central role for central tolerance. Annu Rev Immunol (2006) 4.31
A two-step process for thymic regulatory T cell development. Immunity (2008) 4.29
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med (2005) 4.28
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat Immunol (2007) 4.21
Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. J Immunol (1994) 4.21
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A (2004) 4.12
Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med (1994) 4.10
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity (2006) 4.06
Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis. J Immunol (2006) 4.04
Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells. Immunity (2007) 3.98
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity (2006) 3.96
Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol (2005) 3.95
Suppressor T cells. J Immunol (1972) 3.92
Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol (2003) 3.86
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med (2002) 3.80
How regulatory T cells work. Nat Rev Immunol (2008) 11.66
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol (2004) 10.60
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol (2008) 10.26
The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature (2007) 7.82
Role of LAG-3 in regulatory T cells. Immunity (2004) 4.36
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol (2008) 4.33
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res (2011) 3.81
IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol (2010) 3.43
Dynamic regulatory network controlling TH17 cell differentiation. Nature (2013) 3.07
Generation of T-cell receptor retrogenic mice. Nat Protoc (2006) 3.05
Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex. Science (2008) 2.99
Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nat Methods (2006) 2.87
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol (2009) 2.52
Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). J Immunol (2005) 2.34
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. Nat Immunol (2008) 2.34
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. Immunity (2009) 2.34
Development of 2A peptide-based strategies in the design of multicistronic vectors. Expert Opin Biol Ther (2005) 2.31
The plasticity and stability of regulatory T cells. Nat Rev Immunol (2013) 2.15
Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol (2013) 2.13
Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo. J Immunol (2004) 2.00
Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature (2013) 1.99
General nature of the STAT3-activated anti-inflammatory response. J Immunol (2006) 1.90
Regulatory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner. J Immunol (2009) 1.89
The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells. Eur J Immunol (2003) 1.80
Regulatory T cells and inhibitory cytokines in autoimmunity. Curr Opin Immunol (2009) 1.79
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 1.74
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer. Cancer Res (2004) 1.72
Type 1 diabetes: translating mechanistic observations into effective clinical outcomes. Nat Rev Immunol (2013) 1.65
The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol (2012) 1.63
On the pathogenicity of autoantigen-specific T-cell receptors. Diabetes (2008) 1.61
Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. Immunity (2012) 1.61
Interleukin-35: odd one out or part of the family? Immunol Rev (2008) 1.60
Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells. J Immunol (2009) 1.60
Retracted Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. J Immunol (2011) 1.56
In vitro Treg suppression assays. Methods Mol Biol (2011) 1.46
Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol (2002) 1.43
Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin. Proc Natl Acad Sci U S A (2008) 1.42
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol (2002) 1.41
LAG-3 regulates plasmacytoid dendritic cell homeostasis. J Immunol (2009) 1.33
Metalloproteases regulate T-cell proliferation and effector function via LAG-3. EMBO J (2007) 1.31
Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype. J Immunol (2002) 1.28
Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3. J Immunol (2011) 1.28
Once a Treg, always a Treg? Immunol Rev (2014) 1.27
Design and construction of 2A peptide-linked multicistronic vectors. Cold Spring Harb Protoc (2012) 1.26
Organization of proximal signal initiation at the TCR:CD3 complex. Immunol Rev (2009) 1.25
A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system. Mol Ther (2005) 1.23
The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues. J Immunol (2002) 1.22
Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35. Diabetes (2012) 1.21
Molecular interactions within the IL-6/IL-12 cytokine/receptor superfamily. Immunol Res (2011) 1.19
Cutting edge: regulatory T cells do not require stimulation through their TCR to suppress. J Immunol (2009) 1.17
The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function. J Immunol (2005) 1.13
Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer. J Immunol (2004) 1.13
Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development. EMBO J (2010) 1.11
Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4. Eur J Immunol (2010) 1.09
Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol (2012) 1.09
Germline TRAV5D-4 T-cell receptor sequence targets a primary insulin peptide of NOD mice. Diabetes (2012) 1.09
Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells. J Immunol (2010) 1.07
The proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling. J Immunol (2008) 1.05
The plasticity of regulatory T cell function. J Immunol (2011) 1.03
T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice. Immunology (2012) 1.03
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses. Proc Natl Acad Sci U S A (2011) 0.98
Biochemical analysis of the regulatory T cell protein lymphocyte activation gene-3 (LAG-3; CD223). J Immunol (2004) 0.98
CD40-induced aggregation of MHC class II and CD80 on the cell surface leads to an early enhancement in antigen presentation. J Immunol (2003) 0.98
Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development. J Immunol (2007) 0.97
In vivo Treg suppression assays. Methods Mol Biol (2011) 0.95
Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family. Mol Immunol (2012) 0.94
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. Proc Natl Acad Sci U S A (2013) 0.94
Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways. J Immunol (2011) 0.93
Reliable generation and use of MHC class II:gamma2aFc multimers for the identification of antigen-specific CD4(+) T cells. J Immunol Methods (2002) 0.92
T cell-driven initiation and propagation of autoimmune diabetes. Curr Opin Immunol (2011) 0.92
Development of thymically derived natural regulatory T cells. Ann N Y Acad Sci (2010) 0.91
LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood (2011) 0.91
TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx. J Leukoc Biol (2005) 0.91
Generation of T cell receptor-retrogenic mice: improved retroviral-mediated stem cell gene transfer. Nat Protoc (2013) 0.90
Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection. J Immunol (2014) 0.89
Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection. J Virol (2012) 0.89
STAT heterodimers in immunity: A mixed message or a unique signal? JAKSTAT (2013) 0.89
Interpreting mixed signals: the cell's cytokine conundrum. Curr Opin Immunol (2011) 0.88
Nek2B stimulates zygotic centrosome assembly in Xenopus laevis in a kinase-independent manner. Dev Biol (2004) 0.88
The battle against immunopathology: infectious tolerance mediated by regulatory T cells. Cell Mol Life Sci (2011) 0.87
Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice. J Clin Invest (2011) 0.86
Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation. J Immunol (2004) 0.86
Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. J Immunol Methods (2008) 0.85
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A (2012) 0.85
Transcriptional activation of Mina by Sp1/3 factors. PLoS One (2013) 0.84
Outgrowth of CD4low/negCD25+ T cells with suppressor function in CD4+CD25+ T cell cultures upon polyclonal stimulation ex vivo. J Immunol (2008) 0.84
Plasticity and rigidity in adaptor protein-2-mediated internalization of the TCR:CD3 complex. J Immunol (2005) 0.83
Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind. Diabetes (2012) 0.83
Verification of 2A peptide cleavage. Cold Spring Harb Protoc (2012) 0.82