Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMC 359333)

Published in Mol Cell Biol on December 01, 1994

Authors

R R Mattingly1, A Sorisky, M R Brann, I G Macara

Author Affiliations

1: Department of Microbiology and Molecular Genetics, University of Vermont College of Medicine, Burlington 05405-0068.

Articles citing this

Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes Dev (2004) 2.35

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1. J Cell Biol (1996) 2.06

Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. Proc Natl Acad Sci U S A (2002) 2.06

Denervation suppresses gastric tumorigenesis. Sci Transl Med (2014) 1.96

Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. J Cell Biol (1996) 1.75

The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motif. Proc Natl Acad Sci U S A (1995) 1.62

Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1. Mol Cell Biol (2001) 1.61

Coordination of DNA damage responses via the Smc5/Smc6 complex. Mol Cell Biol (2004) 1.49

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation. EMBO J (1997) 1.45

RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3. Mol Cell Biol (1999) 1.26

Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. Mol Cell Biol (2000) 1.18

Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain. Mol Cell Biol (1998) 1.08

High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis. J Cell Biol (2002) 1.01

The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell-ECM signaling. J Cell Biol (2011) 0.99

Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1. Biochem J (1998) 0.98

Walleye dermal sarcoma virus cyclin interacts with components of the mediator complex and the RNA polymerase II holoenzyme. J Virol (2002) 0.97

The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology. Mol Biol Cell (2006) 0.90

Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src. Biochem J (1999) 0.82

Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C. Virology (2008) 0.81

Identification of Signaling Protein Complexes by Parallel Affinity Precipitation Coupled with Mass Spectrometry. Cell Commun Insights (2013) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

The scanning model for translation: an update. J Cell Biol (1989) 31.23

ras genes. Annu Rev Biochem (1987) 22.59

Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell (1993) 16.91

Crystal structure of a Src-homology 3 (SH3) domain. Nature (1992) 13.88

Proteins regulating Ras and its relatives. Nature (1993) 9.87

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell (1992) 8.20

Identification of a ten-amino acid proline-rich SH3 binding site. Science (1993) 8.05

Structural basis for the binding of proline-rich peptides to SH3 domains. Cell (1994) 6.34

Identification of a family of muscarinic acetylcholine receptor genes. Science (1987) 6.21

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. Science (1993) 6.07

Stimulation of p21ras upon T-cell activation. Nature (1990) 5.72

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell (1993) 5.66

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature (1992) 5.59

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature (1992) 5.47

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature (1986) 4.97

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature (1993) 4.88

The GTPase dynamin binds to and is activated by a subset of SH3 domains. Cell (1993) 4.84

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature (1993) 4.61

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain. Science (1988) 4.58

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science (1992) 4.57

Molecular cloning of two types of GAP complementary DNA from human placenta. Science (1988) 4.39

Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci U S A (1993) 4.30

Signalling through SH2 and SH3 domains. Trends Cell Biol (1993) 3.43

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron (1988) 3.27

Pleckstrin domain homology. Nature (1993) 3.03

Genetics of src: structure and functional organization of a protein tyrosine kinase. Curr Top Microbiol Immunol (1989) 3.03

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit. Science (1994) 2.98

A putative modular domain present in diverse signaling proteins. Cell (1993) 2.90

SH3 domains direct cellular localization of signaling molecules. Cell (1993) 2.73

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol Cell Biol (1994) 2.66

Solution structure of the SH3 domain of Src and identification of its ligand-binding site. Science (1992) 2.56

Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts. Proc Natl Acad Sci U S A (1993) 2.51

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors. EMBO J (1987) 2.39

Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells. J Biol Chem (1993) 2.11

A cytosolic protein catalyzes the release of GDP from p21ras. Science (1990) 2.10

GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. Science (1992) 2.09

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity. Proc Natl Acad Sci U S A (1990) 2.08

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc Natl Acad Sci U S A (1991) 2.00

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell (1991) 1.97

The v-Src SH3 domain binds phosphatidylinositol 3'-kinase. Mol Cell Biol (1993) 1.96

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. Proc Natl Acad Sci U S A (1992) 1.93

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion. EMBO J (1993) 1.91

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels. Cell (1990) 1.67

Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts. J Biol Chem (1993) 1.48

Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J Biol Chem (1993) 1.46

Inhibition of v-src-induced transformation by a GTPase-activating protein. Mol Cell Biol (1991) 1.46

Suppression of src transformation by overexpression of full-length GTPase-activating protein (GAP) or of the GAP C terminus. Mol Cell Biol (1991) 1.44

Structure of the PI3K SH3 domain and analysis of the SH3 family. Cell (1993) 1.42

Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells. J Biol Chem (1994) 1.41

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor. J Biol Chem (1993) 1.40

Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation. J Biol Chem (1994) 1.37

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes. Nature (1989) 1.35

Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes. Oncogene (1991) 1.35

Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling. Science (1993) 1.33

Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-ras. Mol Cell Biol (1992) 1.32

Solution structure of the SH3 domain of phospholipase C-gamma. Cell (1993) 1.31

GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion. Mol Cell Biol (1992) 1.29

Mechanistic aspects of signaling through Ras in NIH 3T3 cells. Science (1992) 1.24

Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors. Mol Cell Biol (1993) 1.15

Enhanced phospholipase C stimulation and transformation in NIH-3T3 cells expressing Q209LGq-alpha-subunits. J Biol Chem (1992) 1.12

S-phase induction and transformation of quiescent NIH 3T3 cells by microinjection of phospholipase C. Proc Natl Acad Sci U S A (1989) 1.07

Acetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activity. Mol Cell Biol (1994) 1.06

Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology. J Virol (1992) 1.05

Differential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein. Proc Natl Acad Sci U S A (1993) 1.04

A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells. J Biol Chem (1993) 1.04

Functional role of GTPase-activating protein in cell transformation by pp60v-src. Mol Cell Biol (1993) 1.01

Enhanced degradation of the phosphoinositidase C-linked guanine-nucleotide-binding protein Gq alpha/G11 alpha following activation of the human M1 muscarinic acetylcholine receptor expressed in CHO cells. Biochem J (1993) 0.99

Activation of transforming G protein-coupled receptors induces rapid tyrosine phosphorylation of cellular proteins, including p125FAK and the p130 v-src substrate. Biochem Biophys Res Commun (1992) 0.92

Transforming G protein-coupled receptors transduce potent mitogenic signals in NIH 3T3 cells independent on cAMP inhibition or conventional protein kinase C. Oncogene (1993) 0.88

The non-catalytic domain of ras-GAP inhibits transformation induced by G protein coupled receptors. Oncogene (1994) 0.83

The ras superfamily of molecular switches. Cell Signal (1991) 0.79

Articles by these authors

(truncated to the top 100)

Identification of a family of muscarinic acetylcholine receptor genes. Science (1987) 6.21

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol (2000) 6.01

CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell (2001) 3.67

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron (1988) 3.27

The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake. Biochem J (1972) 2.86

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature (2001) 2.77

Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export. Science (1997) 2.74

A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat Cell Biol (2001) 2.73

Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci (1991) 2.73

Elevated levels of diacylglycerol and decreased phorbol ester sensitivity in ras-transformed fibroblasts. Nature (1987) 2.68

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Mol Cell Biol (2001) 2.62

Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J Pharmacol Exp Ther (1991) 2.55

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. Mol Pharmacol (1989) 2.42

A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation. J Biol Chem (1994) 2.29

Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis. Proc Natl Acad Sci U S A (1984) 2.23

Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci U S A (1993) 2.10

A cytosolic protein catalyzes the release of GDP from p21ras. Science (1990) 2.10

A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1. J Cell Biol (1996) 2.06

Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. Science (2001) 2.04

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc Natl Acad Sci U S A (1991) 2.00

Nuclear import of Ran is mediated by the transport factor NTF2. Curr Biol (1999) 1.95

Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia. Proc Natl Acad Sci U S A (1990) 1.90

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment. Proc Natl Acad Sci U S A (1990) 1.87

Borg proteins control septin organization and are negatively regulated by Cdc42. Nat Cell Biol (2001) 1.76

Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. J Cell Biol (1996) 1.75

Localization of a family of muscarinic receptor mRNAs in rat brain. J Neurosci (1988) 1.72

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta. J Biol Chem (1997) 1.68

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain. Proc Natl Acad Sci U S A (1986) 1.64

The Ran/TC4 GTPase-binding domain: identification by expression cloning and characterization of a conserved sequence motif. Proc Natl Acad Sci U S A (1995) 1.62

Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature (1990) 1.60

The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1. J Biol Chem (1995) 1.59

D1 and D2 dopamine receptor mRNA in rat brain. Proc Natl Acad Sci U S A (1991) 1.55

Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export. J Cell Biol (2001) 1.55

The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling. J Biol Chem (1998) 1.54

Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms. J Cell Biol (2000) 1.50

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits. Nature (1996) 1.49

Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization. J Biol Chem (1996) 1.48

Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation. Endocrinology (1996) 1.46

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. J Cell Biol (2001) 1.46

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. Mol Cell Biol (1999) 1.43

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine. Psychopharmacology (Berl) (2004) 1.42

Evidence for the involvement of Rab3A in Ca(2+)-dependent exocytosis from adrenal chromaffin cells. J Biol Chem (1994) 1.41

Mutants of Rab3A analogous to oncogenic Ras mutants. Sensitivity to Rab3A-GTPase activating protein and Rab3A-guanine nucleotide releasing factor. J Biol Chem (1993) 1.40

Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion. J Cell Physiol (2001) 1.38

Distinct cellular effects and interactions of the Rho-family GTPase TC10. Curr Biol (1998) 1.37

Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2. EMBO J (2000) 1.34

The formation of ferritin from apoferritin. Catalytic action of apoferritin. Biochem J (1973) 1.34

Amino acid residues in the Ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A. J Biol Chem (1992) 1.33

The release of iron from horse spleen ferritin to 1,10-phenanthroline. Biochem J (1974) 1.33

Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cells. Proc Natl Acad Sci U S A (1988) 1.33

"Thrombin" receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J Biol Chem (1991) 1.32

Ferritin iron uptake and release. Structure-function relationships. Biochem J (1974) 1.31

Glutathione reduces cytoplasmic vanadate. Mechanism and physiological implications. Biochim Biophys Acta (1980) 1.31

Ran binding domains promote the interaction of Ran with p97/beta-karyopherin, linking the docking and translocation steps of nuclear import. J Biol Chem (1996) 1.30

Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. Mol Cell Biol (1995) 1.30

Diurnal expression of transducin mRNA and translocation of transducin in rods of rat retina. Science (1987) 1.29

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur J Immunol (1996) 1.27

Functional TSH receptor in human abdominal preadipocytes and orbital fibroblasts. Am J Physiol Cell Physiol (2000) 1.27

The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain. J Biol Chem (1998) 1.26

RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3. Mol Cell Biol (1999) 1.26

Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers. Mol Pharmacol (1990) 1.26

Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding. EMBO J (1991) 1.25

Immunological detection of muscarinic receptor subtype proteins (m1-m5) in rabbit peripheral tissues. Mol Pharmacol (1991) 1.24

Rapamycin inhibits human adipocyte differentiation in primary culture. Obes Res (2000) 1.24

Down-regulation of protein kinase C and of an endogenous 80-kDa substrate in transformed fibroblasts. J Biol Chem (1987) 1.24

Oncogenes, ions, and phospholipids. Am J Physiol (1985) 1.23

Evidence that a Na+/Ca2+ antiport system regulates murine erythroleukemia cell differentiation. J Biol Chem (1982) 1.20

Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. Mol Cell Biol (2000) 1.18

Ral and Rab3a are major GTP-binding proteins of axonal rapid transport and synaptic vesicles and do not redistribute following depolarization stimulated synaptosomal exocytosis. Biochim Biophys Acta (1993) 1.18

Dopamine D2 receptor dimers and receptor-blocking peptides. Biochem Biophys Res Commun (1996) 1.18

Characterization of a guanine nucleotide-releasing factor and a GTPase-activating protein that are specific for the ras-related protein p25rab3A. Proc Natl Acad Sci U S A (1992) 1.17

Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts. Proc Natl Acad Sci U S A (1990) 1.14

Identification of a small intracellular region of the muscarinic m3 receptor as a determinant of selective coupling to PI turnover. FEBS Lett (1989) 1.12

Regulation of Ras-GAP and the neurofibromatosis-1 gene product by eicosanoids. Science (1991) 1.11

An early decrease in phosphatidylinositol turnover occurs on induction of Friend cell differentiation and precedes the decrease in c-myc expression. Cell (1985) 1.11

5-hydroxytryptamine2A receptor inverse agonists as antipsychotics. J Pharmacol Exp Ther (2001) 1.11

Regulation of the GTPase activity of the ras-like protein p25rab3A. Evidence for a rab3A-specific GAP. J Biol Chem (1991) 1.11

Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes. Biochem Pharmacol (1991) 1.11

Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells. Mol Pharmacol (1991) 1.10

PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10. Biochem Biophys Res Commun (2001) 1.06

Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C. Diabetes (1998) 1.05

The formation of ferritin from apoferritin. Inhibition and metal ion-binding studies. Biochem J (1973) 1.05

Interactions between transport inhibitors at the anion binding sites of the band 3 dimer. Biochemistry (1981) 1.04

Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1. Int J Obes Relat Metab Disord (2004) 1.04

Role of mitochondrial membrane potential in the regulation of murine erythroleukemia cell differentiation. Cell (1982) 1.04

Identification of a ligand-dependent switch within a muscarinic receptor. J Biol Chem (1998) 1.04

Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins. Mol Pharmacol (1997) 1.03

Anti-adipogenic effect of PDGF is reversed by PKC inhibition. J Cell Physiol (2005) 1.03

Phorbol ester-induced translocation of diacylglycerol kinase from the cytosol to the membrane in Swiss 3T3 fibroblasts. J Biol Chem (1989) 1.02

The ras-like protein p25rab3A is partially cytosolic and is expressed only in neural tissue. Mol Cell Biol (1989) 1.02

Stabilization of myc proto-oncogene proteins during Friend murine erythroleukemia cell differentiation. J Biol Chem (1988) 1.02

Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells. J Neurochem (1994) 1.00

Comparison of the effects on secretion in chromaffin and PC12 cells of Rab3 family members and mutants. Evidence that inhibitory effects are independent of direct interaction with Rabphilin3. J Biol Chem (1999) 0.99

Molecular cloning and expression of a dopamine D2 receptor from human retina. Mol Pharmacol (1990) 0.98

Chimeric m2/m3 muscarinic receptors: role of carboxyl terminal receptor domains in selectivity of ligand binding and coupling to phosphoinositide hydrolysis. Mol Pharmacol (1990) 0.98

Electrophysiological characterization of cloned m1 muscarinic receptors expressed in A9 L cells. Proc Natl Acad Sci U S A (1988) 0.97

Interleukin-6 release from human abdominal adipose cells is regulated by thyroid-stimulating hormone: effect of adipocyte differentiation and anatomic depot. Am J Physiol Endocrinol Metab (2006) 0.97

The Rab3A GTPase interacts with multiple factors through the same effector domain. Mutational analysis of cross-linking of Rab3A to a putative target protein. J Biol Chem (1993) 0.96

Evidence that inhibitors of anion exchange induce a transmembrane conformational change in band 3. J Biol Chem (1983) 0.96

Macrophage-conditioned medium inhibits the differentiation of 3T3-L1 and human abdominal preadipocytes. Diabetologia (2006) 0.95