Published in Nucleic Acids Res on October 25, 1994
Sorting out the complexity of SR protein functions. RNA (2000) 9.25
The regulation of splice-site selection, and its role in human disease. Am J Hum Genet (1997) 2.06
SR protein splicing factors interact with the Rous sarcoma virus negative regulator of splicing element. J Virol (1996) 1.49
Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stability. BMC Genomics (2004) 1.47
The SRm160/300 splicing coactivator subunits. RNA (2000) 1.43
Genetic enhancement of RNA-processing defects by a dominant mutation in B52, the Drosophila gene for an SR protein splicing factor. Mol Cell Biol (1995) 1.41
Autoregulation of transformer-2 alternative splicing is necessary for normal male fertility in Drosophila. Genetics (1998) 1.01
Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Res (1996) 0.98
Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. Mol Cell Biol (1998) 0.94
The small ubiquitin-like modifier (SUMO) and SUMO-conjugating system of Chlamydomonas reinhardtii. Genetics (2008) 0.93
Structure and assembly of the SF3a splicing factor complex of U2 snRNP. EMBO J (2012) 0.89
The evolutionarily conserved TOUGH protein is required for proper development of Arabidopsis thaliana. Plant Cell (2005) 0.82
Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins. Nucleic Acids Res (2015) 0.77
SUGP1 is a novel regulator of cholesterol metabolism. Hum Mol Genet (2016) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98
dbEST--database for "expressed sequence tags". Nat Genet (1993) 41.10
Unidirectional digestion with exonuclease III in DNA sequence analysis. Methods Enzymol (1987) 10.31
RNA recognition: towards identifying determinants of specificity. Trends Biochem Sci (1991) 9.03
Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell (1992) 7.90
Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators. Cell (1991) 6.50
Alternative splicing in the control of gene expression. Annu Rev Genet (1989) 6.18
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell (1991) 5.72
Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation. Trends Biochem Sci (1988) 5.47
Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm. Cell (1989) 5.46
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell (1993) 4.82
Distinct functions of SR proteins in alternative pre-mRNA splicing. Science (1993) 4.79
The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis. Nature (1989) 4.70
A survey of expressed genes in Caenorhabditis elegans. Nat Genet (1992) 4.63
Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins. Cell (1988) 4.52
Sex in flies: the splice of life. Nature (1989) 4.04
Pre-mRNA splicing in yeast. Trends Genet (1991) 3.98
The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature (1993) 3.97
Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell (1987) 3.86
Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem (1987) 3.41
Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF. EMBO J (1993) 3.11
On the antiquity of introns. Cell (1986) 2.98
On/off regulation of gene expression at the level of splicing. Trends Genet (1988) 2.81
Alternative mRNA splicing. Annu Rev Cell Biol (1992) 2.74
Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell (1991) 2.69
Structural basis for the regulation of splicing of a yeast messenger RNA. Cell (1991) 2.59
Mechanisms of alternative pre-mRNA splicing. Science (1991) 2.54
The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell (1988) 2.47
Developmental expression of a regulatory gene is programmed at the level of splicing. EMBO J (1987) 2.30
Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9. Science (1993) 2.27
Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA. Genes Dev (1993) 2.03
Genetic interactions of modifier genes and modifiable alleles in Drosophila melanogaster. Genetics (1988) 1.99
Interaction between PRP11 and SPP91 yeast splicing factors and characterization of a PRP9-PRP11-SPP91 complex. Science (1993) 1.90
Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans. J Cell Biol (1993) 1.85
Evidence that a regulatory gene autoregulates splicing of its transcript. EMBO J (1987) 1.80
Correspondence between a mammalian spliceosome component and an essential yeast splicing factor. Science (1993) 1.71
Autoregulation and multifunctionality among trans-acting factors that regulate alternative pre-mRNA processing. J Biol Chem (1992) 1.71
A "housekeeping" gene on the X chromosome encodes a protein similar to ubiquitin. Proc Natl Acad Sci U S A (1988) 1.60
A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc Natl Acad Sci U S A (1990) 1.59
Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development (1992) 1.46
A novel gene, spp91-1, suppresses the splicing defect and the pre-mRNA nuclear export in the prp9-1 mutant. EMBO J (1992) 1.31
Introns excised from the Delta primary transcript are localized near sites of Delta transcription. J Cell Biol (1992) 1.30
Interactions between PRP9 and SPP91 splicing factors identify a protein complex required in prespliceosome assembly. Genes Dev (1993) 1.24
The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome. Proc Natl Acad Sci U S A (1993) 1.15
Analysis of autoregulation at the level of pre-mRNA splicing of the suppressor-of-white-apricot gene in Drosophila. Genetics (1994) 1.01
Analysis of spliceosome assembly and the structure of a regulated intron in Drosophila in vitro splicing extracts. Nucleic Acids Res (1992) 1.00
Genomic structure and expression of the human fau gene: encoding the ribosomal protein S30 fused to a ubiquitin-like protein. Biochem Biophys Res Commun (1992) 0.93
Applying genetics to the splicing problem. Genes Dev (1987) 0.90
Novel ubiquitin-like ribosomal protein fusion genes from the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. J Biol Chem (1993) 0.88
Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method. Cell (1981) 11.51
The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family. Cell (1982) 8.95
The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations. Cell (1982) 7.07
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature (2000) 5.86
The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence. Cell (1979) 5.83
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
Regulation of white locus expression: the structure of mutant alleles at the white locus of Drosophila melanogaster. Cell (1982) 4.09
Physical map of the white locus of Drosophila melanogaster. Proc Natl Acad Sci U S A (1982) 3.46
Molecular cloning of sequences from a Drosophila RNA polymerase II locus by P element transposon tagging. Cell (1982) 3.30
A copy of the copia transposable element is very tightly linked to the Wa allele at the white locus of D. melanogaster. Cell (1981) 2.99
Trans splicing involves a novel form of small nuclear ribonucleoprotein particles. Nature (1988) 2.87
Cognitive decline in women in relation to non-protein-bound oestradiol concentrations. Lancet (2000) 2.82
On/off regulation of gene expression at the level of splicing. Trends Genet (1988) 2.81
Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell (1991) 2.69
SSC1, an essential member of the yeast HSP70 multigene family, encodes a mitochondrial protein. Mol Cell Biol (1989) 2.52
Genetic and physical studies of a portion of the white locus participating in transcriptional regulation and in synapsis-dependent interactions in Drosophila adult tissues. Genetics (1985) 2.52
Evidence that two mutations, wDZL and z1, affecting synapsis-dependent genetic behavior of white are transcriptional regulatory mutations. Cell (1985) 2.44
Developmental expression of a regulatory gene is programmed at the level of splicing. EMBO J (1987) 2.30
Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA. J Virol (1984) 2.28
Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf. J Biol Chem (1999) 2.15
SSC1, a member of the 70-kDa heat shock protein multigene family of Saccharomyces cerevisiae, is essential for growth. Proc Natl Acad Sci U S A (1987) 2.10
ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. Mol Psychiatry (2011) 2.05
A detailed developmental and structural study of the transcriptional effects of insertion of the Copia transposon into the white locus of Drosophila melanogaster. Genetics (1985) 1.99
Bone-marrow oedema syndrome and transient osteoporosis of the hip. An MRI-controlled study of treatment by core decompression. J Bone Joint Surg Br (1993) 1.99
Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans. J Cell Biol (1993) 1.85
Evidence that a regulatory gene autoregulates splicing of its transcript. EMBO J (1987) 1.80
Presence of the Caenorhabditis elegans spliced leader on different mRNAs and in different genera of nematodes. Genes Dev (1988) 1.78
A large outbreak of gastroenteritis caused by diarrheal toxin-producing Bacillus cereus. J Infect Dis (1993) 1.63
Lesions of the acetabular labrum: accuracy of MR imaging and MR arthrography in detection and staging. Radiology (1996) 1.54
Introduction of the new Centers for Disease Control and Prevention group B streptococcal prevention guideline at a large West Coast health maintenance organization. Am J Obstet Gynecol (2001) 1.51
Confirmation of administrative claims-identified opportunistic infections and other serious potential adverse events associated with tumor necrosis factor alpha antagonists and disease-modifying antirheumatic drugs. Arthritis Rheum (2007) 1.43
Speech and language delay are early manifestations of juvenile-onset Huntington disease. Neurology (2006) 1.43
Production of lymphotoxin and migration inhibitory factor by established human lymphocytic cell lines. J Immunol (1970) 1.43
An analysis of advertisements in the Journal of the American Academy of Dermatology, 1980 and 1990. J Am Acad Dermatol (1993) 1.42
On the theory of speciation induced by transposable elements. Genetics (1984) 1.40
On the molecular basis of transvection effects and the regulation of transcription. Cold Spring Harb Symp Quant Biol (1985) 1.37
Verbal and design fluency in patients with frontal lobe lesions. J Int Neuropsychol Soc (2001) 1.36
A novel dominant mutant allele at the white locus of Drosophila melanogaster is mutable. Cold Spring Harb Symp Quant Biol (1981) 1.35
Efficient transformation of human fibroblasts by adenovirus-simian virus 40 recombinants. Mol Cell Biol (1984) 1.35
What is the best way of assessing outcome after total knee replacement? Clin Orthop Relat Res (1996) 1.35
The life-time rates of three major mood disorders and four major anxiety disorders in alcoholics and controls. Addiction (1997) 1.34
Abnormalities of articular cartilage in the knee: analysis of available MR techniques. Radiology (1993) 1.24
Heat mutagenesis in bacteriophage T4: the transition pathway. Proc Natl Acad Sci U S A (1976) 1.24
Functional anatomy of the levator palpebrae superioris muscle and its connective tissue system. Br J Ophthalmol (1996) 1.24
Which came first, MHC class I or class II? Immunogenetics (1991) 1.22
Genome-wide association study of conduct disorder symptomatology. Mol Psychiatry (2010) 1.22
Magnetic resonance imaging of articular cartilage. Clin Orthop Relat Res (2001) 1.22
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Mol Psychiatry (2012) 1.21
Method for the quantitative assessment of contrast agent uptake in dynamic contrast-enhanced MRI. Magn Reson Med (1994) 1.21
Effect of gender on the outcomes of contemporary percutaneous coronary intervention. Am J Cardiol (2001) 1.21
Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes. Proc Natl Acad Sci U S A (2000) 1.19
Palindromic adenovirus type 5-simian virus 40 hybrid. J Virol (1983) 1.15
Histomorphology and bone morphometry of the bone marrow edema syndrome of the hip. Clin Orthop Relat Res (1997) 1.15
Repeatability of subjective evaluation of lameness in horses. Equine Vet J (2010) 1.14
Stable gene transfer and tissue-specific expression of a human globin gene using adenoviral vectors. EMBO J (1986) 1.13
Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization. Nat Cell Biol (2001) 1.13
Embolization of bone metastases. J Vasc Interv Radiol (1996) 1.10
Differential regulation of the expression of proteinases/antiproteinases in fibroblasts. Effects of interleukin-1 and platelet-derived growth factor. J Biol Chem (1991) 1.10
Serum Lp(a) level as a predictor of vein graft stenosis after coronary artery bypass surgery in patients. Circulation (1988) 1.09
Altered glucose tolerance, insulin response, and insulin sensitivity after massive weight reduction subsequent to gastric bypass. Surgery (1982) 1.08
Selective reduction of N-acetylaspartate in medial temporal and parietal lobes in AD. Neurology (2002) 1.08
A genome-wide screen for genes influencing conduct disorder. Mol Psychiatry (2004) 1.07
A Canadian survey of issues in cancer pain management. J Pain Symptom Manage (1997) 1.06
Changing behavior. Practical lessons from the diabetes control and complications trial. Diabetes Care (1996) 1.05
Molecular cloning and genetic analysis of the suppressor-of-white-apricot locus from Drosophila melanogaster. Mol Cell Biol (1987) 1.04
Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes. Genes Immun (2012) 1.04
Analysis of autoregulation at the level of pre-mRNA splicing of the suppressor-of-white-apricot gene in Drosophila. Genetics (1994) 1.01
Cranial MRI in Wilson's disease. Neuroradiology (1990) 1.01
Improved time-of-flight MR angiography of the brain with magnetization transfer contrast. Radiology (1992) 1.00
Long-term neurobehavioral outcomes in children with neuroblastoma and opsoclonus-myoclonus-ataxia syndrome: relationship to MRI findings and anti-neuronal antibodies. J Pediatr (2001) 1.00
Analysis of spliceosome assembly and the structure of a regulated intron in Drosophila in vitro splicing extracts. Nucleic Acids Res (1992) 1.00
Heat mutagenesis in bacteriophage T4: the transversion pathway. Proc Natl Acad Sci U S A (1976) 1.00
Sendai virus-like particles devoid of haemagglutinin-neuraminidase protein infect cells via the human asialoglycoprotein receptor. J Gen Virol (1998) 0.99
Evolution of the major histocompatibility complex: molecular cloning of major histocompatibility complex class I from the amphibian Xenopus. Proc Natl Acad Sci U S A (1991) 0.98
Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. Genes Brain Behav (2012) 0.98
A rapid microdilution technique for counting viable bacteria in food. Lab Pract (1977) 0.98
MR arthrography of the adult acetabular capsular-labral complex: correlation with surgery and anatomy. AJR Am J Roentgenol (1999) 0.98
MRI in basal ganglia diseases. J Neural Transm Suppl (1991) 0.98
Ethnic minorities, health care systems, and behavior. Health Psychol (1995) 0.97
Evaluation of mild lameness in horses trotting on a treadmill by clinicians and interns or residents and correlation of their assessments with kinematic gait analysis. Am J Vet Res (1998) 0.97
Pituitary adenomas: findings of postoperative MR imaging. Radiology (1992) 0.97
Haemorrhage in intracerebral arteriovenous malformations: detection with MRI and comparison with clinical history. Neuroradiology (1993) 0.96
Flow cytometric analysis of micronuclei found in cells after irradiation. Cytometry (1984) 0.95
Resurfacing versus not resurfacing the patella during total knee replacement. Clin Orthop Relat Res (1995) 0.94
Actin gene expression in developing sea urchin embryos. Mol Cell Biol (1981) 0.94
Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation. Cell Death Differ (2011) 0.94
Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest. Vet Pathol (2009) 0.93
Dysfunctional C1 inhibitor Ta: deletion of Lys-251 results in acquisition of an N-glycosylation site. Proc Natl Acad Sci U S A (1990) 0.93
Immunomodulation by probiotic lactobacilli in layer- and meat-type chickens. Br Poult Sci (2004) 0.93
Hip abduction-adduction strength and one-leg hop tests: test-retest reliability and relationship to function in elite ice hockey players. J Orthop Sports Phys Ther (2001) 0.93
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene. Oncogene (2009) 0.93
Cognitive consequences and central nervous system injury following treatment for childhood leukemia. Semin Oncol Nurs (2000) 0.93
Intrarenal distribution of penicillin, cephalothin, ampicillin and oxytetracycline during varied states of hydration. J Pharmacol Exp Ther (1971) 0.92
Resurfacing versus not resurfacing the patella in total knee arthroplasty: 8- to 10-year results. J Arthroplasty (2003) 0.92
CT and MR accuracy in the detection of tumor recurrence in patients treated for ovarian cancer. J Comput Assist Tomogr (1993) 0.91
Preoperative assessment of the carotid bifurcation. Can magnetic resonance angiography and duplex ultrasonography replace contrast arteriography? Stroke (1995) 0.91
Cortical atrophy in young adults with a history of hyperactivity in childhood. Psychiatry Res (1986) 0.91