Published in Protein Eng on July 01, 1994
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Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. J Cell Biol (1996) 1.19
Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol (1996) 1.17
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The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin. EMBO J (1994) 1.11
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Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1. J Biol Chem (1998) 1.06
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Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1. J Biol Chem (1993) 0.98
Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: a candidate therapeutic for IDDM and SLE. Cytokine (2001) 0.98
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Mutational analysis of thrombopoietin for identification of receptor and neutralizing antibody sites. J Biol Chem (1997) 0.93
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Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for alpha 4 beta 7 and role in experimental colitis. Immunol Res (1997) 0.91
Similar but nonidentical amino acid residues on vascular cell adhesion molecule-1 are involved in the interaction with alpha 4 beta 1 and alpha 4 beta 7 under different activity states. J Immunol (1995) 0.90
Development of a humanized disulfide-stabilized anti-p185HER2 Fv-beta-lactamase fusion protein for activation of a cephalosporin doxorubicin prodrug. Cancer Res (1995) 0.90
Modulation of megakaryocytopoiesis by human macrophage-stimulating protein, the ligand for the RON receptor. J Immunol (1996) 0.89
Remodeling domain interfaces to enhance heterodimer formation. Protein Sci (1997) 0.86
Reduction of alpha-naphthylisothiocyanate-induced hepatotoxicity by recombinant human hepatocyte growth factor. Endocrinology (1992) 0.86
Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to alpha 4 beta 1. J Cell Biol (1994) 0.85
Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability. J Biol Chem (1998) 0.85
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TrkA amino acids controlling specificity for nerve growth factor. J Biol Chem (2000) 0.81
The pharmacokinetics, tissue localization, and metabolic processing of recombinant human hepatocyte growth factor after intravenous administration in rats. Endocrinology (1994) 0.81
Specificity determinants in neurotrophin-3 and design of nerve growth factor-based trkC agonists by changing central beta-strand bundle residues to their neurotrophin-3 analogs. Biochemistry (1997) 0.79
Development of neurotrophic factor therapy for Alzheimer's disease. Ciba Found Symp (1996) 0.79
New branches on the neuregulin family tree. Mol Psychiatry (1998) 0.78
Human anti-IgE monoclonal antibody blocks passive sensitization of human and rhesus monkey bladder. J Urol (1997) 0.78
Humanization of an antibody against human protein C and calcium-dependence involving framework residues. Protein Eng (1998) 0.77
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Anti-IgE monoclonal antibodies that inhibit allergen-specific histamine release. Int Arch Allergy Immunol (1995) 0.75
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Crystal structures of the complex of porcine pancreatic elastase with two valine-derived benzoxazinone inhibitors. J Mol Biol (1987) 0.75