PubRank

B von Wilcken-Bergmann

Author PubWeight™ 42.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 lac repressor forms loops with linear DNA carrying two suitably spaced lac operators. EMBO J 1987 4.02
2 Quality and position of the three lac operators of E. coli define efficiency of repression. EMBO J 1994 2.90
3 Sequence of galR gene indicates a common evolutionary origin of lac and gal repressor in Escherichia coli. Proc Natl Acad Sci U S A 1982 2.77
4 Possible ideal lac operator: Escherichia coli lac operator-like sequences from eukaryotic genomes lack the central G X C pair. Proc Natl Acad Sci U S A 1984 2.64
5 Synthetic lac operator mediates repression through lac repressor when introduced upstream and downstream from lac promoter. EMBO J 1986 1.80
6 Mutant lac repressors with new specificities hint at rules for protein--DNA recognition. EMBO J 1990 1.77
7 Recognition helices of lac and lambda repressor are oriented in opposite directions and recognize similar DNA sequences. Proc Natl Acad Sci U S A 1988 1.64
8 Four dimers of lambda repressor bound to two suitably spaced pairs of lambda operators form octamers and DNA loops over large distances. Curr Biol 1999 1.63
9 Specific destruction of the second lac operator decreases repression of the lac operon in Escherichia coli fivefold. J Mol Biol 1987 1.62
10 How Trp repressor binds to its operator. EMBO J 1990 1.53
11 Identification of three residues in the basic regions of the bZIP proteins GCN4, C/EBP and TAF-1 that are involved in specific DNA binding. EMBO J 1993 1.46
12 Dimer-to-tetramer assembly of Lac repressor involves a leucine heptad repeat. New Biol 1991 1.35
13 Genetic analysis of the leucine heptad repeats of Lac repressor: evidence for a 4-helical bundle. EMBO J 1993 1.27
14 lac repressor mutants with double or triple exchanges in the recognition helix bind specifically to lac operator variants with multiple exchanges. EMBO J 1989 1.18
15 Replacement of invariant bZip residues within the basic region of the yeast transcriptional activator GCN4 can change its DNA binding specificity. Nucleic Acids Res 1994 1.03
16 A model of the lac repressor-operator complex based on physical and genetic data. Eur J Biochem 1991 0.99
17 Lac repressor with the helix-turn-helix motif of lambda cro binds to lac operator. EMBO J 1992 0.95
18 gal4 transcription activator protein of yeast can function as a repressor in Escherichia coli. EMBO J 1987 0.94
19 The DNA binding specificity of the basic region of the yeast transcriptional activator GCN4 can be changed by substitution of a single amino acid. Nucleic Acids Res 1993 0.93
20 A synthetic operon containing 14 bovine pancreatic trypsin inhibitor genes is expressed in E. coli. EMBO J 1986 0.92
21 Creating new DNA binding specificities in the yeast transcriptional activator GCN4 by combining selected amino acid substitutions. Nucleic Acids Res 1994 0.91
22 The roles of residues 5 and 9 of the recognition helix of Lac repressor in lac operator binding. J Mol Biol 1991 0.90
23 A positive selection vector for cloning of long polymerase chain reaction fragments based on a lethal mutant of the crp gene of Escherichia coli. Anal Biochem 1998 0.87
24 Repression of the E. coli lactose operon by cooperation between two individually unproductive "half-operator" sites. C R Acad Sci III 1992 0.84
25 A comparison of the different DNA binding specificities of the bZip proteins C/EBP and GCN4. Nucleic Acids Res 1995 0.84
26 cDNA from rat cells with reconstitutive galactose-epimerase activity in E. coli. Nucleic Acids Res 1990 0.84
27 Linker mutagenesis in the lacZ gene of Escherichia coli yields variants of active beta-galactosidase. Eur J Biochem 1991 0.83
28 Synthesis of chimeric mouse nerve growth factor precursor and human beta-nerve growth factor in Escherichia coli: immunological properties. J Neurosci Res 1989 0.77
29 The possible roles of residues 79 and 80 of the Trp repressor from Escherichia coli K-12 in trp operator recognition. Mol Gen Genet 1995 0.76
30 Mutant bZip-DNA complexes with four quasi-identical protein-DNA interfaces. EMBO J 1996 0.75
31 A lethal mutant of the catabolite gene activator protein CAP of Escherichia coli. Biol Chem 1997 0.75
32 Mutants with substitutions for Glu171 in the catabolite activator protein (CAP) of Escherichia coli activate transcription from the lac promoter. Mol Gen Genet 1993 0.75
33 Expression of adenovirus type 12 E1b 58-kDa protein in Escherichia coli and production of antibodies raised against a 58-kDa::beta-galactosidase fusion protein. Gene 1987 0.75
34 Co-operative binding of two Trp repressor dimers to alpha- or beta-centred trp operators. Mol Microbiol 1996 0.75