Published in Biochem Biophys Res Commun on December 28, 1979
Slow reacting substances of anaphylaxis: identification of leukotrienes C-1 and D from human and rat sources. Proc Natl Acad Sci U S A (1980) 3.18
Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci U S A (1980) 2.94
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1980) 2.77
Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus. Proc Natl Acad Sci U S A (1980) 2.53
Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4. Proc Natl Acad Sci U S A (1983) 2.01
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A (1986) 1.97
Dynamics of leukotriene C production by macrophages. J Exp Med (1980) 1.93
Secretion of leukotriene C and other arachidonic acid metabolites by macrophages challenged with immunoglobulin E immune complexes. J Exp Med (1982) 1.73
Synthesis of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophages. J Exp Med (1982) 1.54
Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids. Proc Natl Acad Sci U S A (1982) 1.52
Leukotriene generation by eosinophils. J Exp Med (1982) 1.29
Characterization of slow reacting substances (SRSs) of rat basophilic leukemia (RBL-1) cells: effect of cysteine on SRS profile. Proc Natl Acad Sci U S A (1980) 1.19
Depletion of glutathione selectively inhibits synthesis of leukotriene C by macrophages. Proc Natl Acad Sci U S A (1981) 1.13
Contractile activities of structural analogs of leukotrienes C and D: necessity of a hydrophobic region. Proc Natl Acad Sci U S A (1981) 1.02
Stimulation of human endothelial cell prostacyclin synthesis by select leukotrienes. J Exp Med (1984) 0.98
Identification of the slow reacting substances from cat paws. Proc Natl Acad Sci U S A (1980) 0.94
Slow reacting substances (leukotrienes): enzymes involved in their biosynthesis. Proc Natl Acad Sci U S A (1982) 0.92
Arachidonic acid metabolism in glutathione-deficient macrophages. Proc Natl Acad Sci U S A (1982) 0.91
Inhibition and recognition studies on the glutathione-binding site of equine liver glutathione S-transferase. Biochem J (1990) 0.89
Release of a slow-reacting substance from rabbit platelets. J Clin Invest (1981) 0.84
Leukotriene C synthase in mouse mastocytoma cells. An enzyme distinct from cytosolic and microsomal glutathione transferases. Biochem J (1988) 0.82
Purification and characterization of human hepatic cysteine-conjugate beta-lyase. Biochem J (1986) 0.78
Disruption of the alox5ap gene ameliorates focal ischemic stroke: possible consequence of impaired leukotriene biosynthesis. BMC Neurosci (2012) 0.77
A low molecular weight proinflammatory factor from rat spleen lymphocytes. Isolation and partial characterization. Inflammation (2007) 0.76
Proceedings of the British Pharmacological Society. 16--18th December, 1980. Br J Pharmacol (1981) 0.75
Formation of 11-trans slow reacting substances. Proc Natl Acad Sci U S A (1981) 0.75
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82
Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science (1983) 9.51
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science (1995) 8.58
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science (1987) 8.36
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A (1974) 8.30
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187. Proc Natl Acad Sci U S A (1979) 6.34
Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci U S A (1979) 5.33
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. Proc Natl Acad Sci U S A (1999) 5.08
Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43
Titration of antibodies to salmonella O antigens by enzyme-linked immunosorbent assay. Infect Immun (1972) 4.13
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
Leukotrienes are potent constrictors of human bronchi. Nature (1980) 4.04
Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function. N Engl J Med (1985) 4.00
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. J Biol Chem (1976) 3.82
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A (1999) 3.61
Prostaglandins and thromboxanes. Annu Rev Biochem (1978) 3.47
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A (1981) 3.42
Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem (1968) 3.41
On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase. J Biol Chem (1967) 3.30
Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin. J Invest Dermatol (1983) 3.18
Slow reacting substances of anaphylaxis: identification of leukotrienes C-1 and D from human and rat sources. Proc Natl Acad Sci U S A (1980) 3.18
Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. J Biol Chem (1979) 3.16
Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. Proc Natl Acad Sci U S A (1979) 3.14
Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. J Biol Chem (1979) 3.08
Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate-dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes. Scand J Immunol (2004) 3.03
Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci U S A (1980) 2.94
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. J Biol Chem (1967) 2.93
Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial. J Clin Oncol (1988) 2.91
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1980) 2.77
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis. Proc Natl Acad Sci U S A (1975) 2.75
Antigen from colon of germfree rats and antibodies in human ulcerative colitis. Ann N Y Acad Sci (1965) 2.72
Diffusion-limited reaction of free nitric oxide with erythrocytes. J Biol Chem (1998) 2.66
Appraising Public Medical Services. Am J Public Health Nations Health (1941) 2.62
The Function of Ac-Globulin in Blood Clotting. Science (1947) 2.62
Prostaglandin endoperoxides. VII. Novel transformations of arachidonic acid in guinea pig lung. Biochem Biophys Res Commun (1974) 2.56
An information processing model of anxiety: automatic and strategic processes. Behav Res Ther (1997) 2.55
Amelioration of chronic ileitis by nitric oxide synthase inhibition. J Pharmacol Exp Ther (1993) 2.54
Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity. Biochem Biophys Res Commun (1980) 2.49
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci U S A (1984) 2.46
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
The cardiac donor. Surg Gynecol Obstet (1971) 2.39
Infectious complications after cardiac transplantation in man. Ann Intern Med (1971) 2.37
The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis. J Immunol (1973) 2.34
Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res (1999) 2.25
Biosynthesis of prostaglandins. Fed Proc (1972) 2.23
Biosynthesis of prostaglandins from arachidonic acid in guinea pig lung. Prostaglandins and related factors. 38. J Biol Chem (1965) 2.23
Haemolytic activity of human blood monocytes. Lysis of human erythrocytes treated with anti-A serum. Clin Exp Immunol (1973) 2.21
Inactivation of slow reacting substance of anaphylaxins (SRS-A) by arylsulfatases. J Immunol (1974) 2.19
Telaprevir or boceprevir triple therapy in patients with chronic hepatitis C and varying severity of cirrhosis. Aliment Pharmacol Ther (2014) 2.18
Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria. J Exp Med (1982) 2.12
Immunological studies in ulcerative colitis. 3. Incidence of antibodies to colon-antigen in ulcerative colitis and other gastro-intestinal diseases. Clin Exp Immunol (1966) 2.11
Prostaglandins. Annu Rev Biochem (1975) 2.09
American College of Cardiology/Society for Cardiac Angiography and Interventions Clinical Expert Consensus Document on cardiac catheterization laboratory standards. A report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol (2001) 2.09
Proteasome inhibitors block development of Plasmodium spp. Antimicrob Agents Chemother (1998) 2.07
Leukotriene B4 action on endothelium mediates augmented neutrophil/endothelial adhesion. Proc Natl Acad Sci U S A (1984) 2.06
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc Natl Acad Sci U S A (1984) 2.05
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence. Blood (1981) 2.05
Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes. FEBS Lett (1981) 2.04
On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha. J Biol Chem (1967) 2.02
Immunological studies in ulcerative colitis. IV. Origin of autoantibodies. J Exp Med (1968) 2.02
Longitudinal study of serum lipids. 12-year report. Am J Clin Nutr (1967) 2.00
Cardiac catheterization 1990: a report of the Registry of the Society for Cardiac Angiography and Interventions (SCA&I). Cathet Cardiovasc Diagn (1991) 2.00
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A (1986) 1.97
The chemical composition of the cytoplasmic membrane of Bacillus subtilis. Eur J Biochem (1967) 1.96
Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology (2009) 1.93
On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. Proc Natl Acad Sci U S A (1985) 1.91
Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4. Proc Natl Acad Sci U S A (1983) 1.91
Bronchoconstrictor effects of leukotriene C in humans. Science (1982) 1.91
Prostaglandins in human seminal plasma. Prostaglandins and related factors 46. J Biol Chem (1966) 1.91
Phospholipid precursors of prostaglandins. Biochim Biophys Acta (1968) 1.90
Triflimide activation of a chiral oxazaborolidine leads to a more general catalytic system for enantioselective Diels-Alder addition. J Am Chem Soc (2003) 1.89
Prostaglandin endoperoxides IV. Effects on smooth muscle. Life Sci (1975) 1.89
Autoantibodies to colon in rats and human ulcerative colitis: cross reactivity with Escherichia coli O:14 antigen. Proc Soc Exp Biol Med (1967) 1.86
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem (2001) 1.86
Evidence for a common mucosal immunologic system. II. Influence of the estrous cycle on B immunoblast migration into genital and intestinal tissues. J Immunol (1980) 1.79
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. Proc Natl Acad Sci U S A (1975) 1.74
Novel acetoxylation and C-C coupling reactions at unactivated positions in alpha-amino acid derivatives. Org Lett (2006) 1.74
On the metabolism of prostaglandins E 1 and E 2 in man. J Biol Chem (1971) 1.71
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis. Clin Exp Immunol (2003) 1.70
Effects of leukotriene D on the airways in asthma. N Engl J Med (1983) 1.69
Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. Biochem Biophys Res Commun (1982) 1.69
A soluble 2,3-oxidosqualene sterol cyclase. J Biol Chem (1967) 1.68
Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. Proc Natl Acad Sci U S A (1983) 1.67
Quantitation of Salmonella O-antibodies in human sera by enzyme-linked immunosorbent assay (ELISA). Int Arch Allergy Appl Immunol (1975) 1.66
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils. J Clin Invest (1984) 1.65
Synthesis and biological properties of a 9,11-azo-prostanoid: highly active biochemical mimic of prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 1.64