Published in J Virol on October 01, 1978
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Quantitation of Simian virus 40 sequences in African green monkey, mouse and virus-transformed cell genomes. J Mol Biol (1971) 7.10
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An electron microscopic method for studying and mapping the region of weak sequence homology between simian virus 40 and polyoma DNAs. J Mol Biol (1975) 1.35
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Polynucleotide sequences common to the genomes of simian virus 40 and the human papovaviruses JC and BK. Virology (1976) 1.25
Identification of the stumptailed macaque virus as a new papovavirus. Infect Immun (1976) 1.23
Characterization of SA12 as a simian virus 40-related papovavirus of chacma baboons. Infect Immun (1977) 1.14
Pathology of a pneumotropic virus recovered from C3H mice carrying the Bittner milk agent. AMA Arch Pathol (1953) 1.07
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Presence of K-virus in wild mice in Australia. Aust J Exp Biol Med Sci (1959) 0.95
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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (1989) 16.54
Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (1990) 12.88
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell (1993) 12.41
Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol (1989) 8.68
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J (1989) 7.69
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell (1985) 7.56
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01
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In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J Virol (1987) 6.65
Mutants of simian virus 40 differing in plaque size, oncogenicity, and heat sensitivity. J Bacteriol (1966) 6.41
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell (1988) 6.28
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18
A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell (1987) 5.75
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J (1991) 5.39
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1995) 5.37
A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes. J Biol Chem (1979) 5.32
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc Natl Acad Sci U S A (1991) 5.31
Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci U S A (1982) 5.22
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89
Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77
Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol (1981) 4.75
Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology (1982) 4.52
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science (1999) 4.21
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev (1998) 4.06
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol (1993) 4.04
Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. EMBO J (1987) 3.77
Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. J Virol (1987) 3.66
Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1. Nature (1986) 3.63
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55
In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res (1996) 3.50
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell (2000) 3.39
Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol (1980) 3.34
p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27
The papillomavirus E2 regulatory proteins. J Biol Chem (1991) 3.27
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J Virol (1987) 3.24
The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. EMBO J (1988) 3.20
E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc Natl Acad Sci U S A (1989) 3.18
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol Cell (1998) 3.12
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc Natl Acad Sci U S A (1994) 3.12
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J (1992) 2.97
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol (1990) 2.90
Transcriptional organization of bovine papillomavirus type 1. J Virol (1983) 2.84
Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice. J Virol (1994) 2.73
Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes. J Virol (1983) 2.69
Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions. J Virol (1986) 2.62
Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40. J Virol (1973) 2.54
Transient replication of human papillomavirus DNAs. J Virol (1992) 2.43
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol (1997) 2.41
Enhanced growth of a murine coronavirus in transformed mouse cells. Infect Immun (1972) 2.35
Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci U S A (1992) 2.30
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci U S A (1996) 2.30
The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes Dev (1991) 2.24
Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein. J Virol (1992) 2.24
Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J Biol Chem (1997) 2.23
A stable bovine papillomavirus hybrid plasmid that expresses a dominant selective trait. Mol Cell Biol (1983) 2.21
Comparison of Southern blot hybridization and polymerase chain reaction methods for the detection of human papillomavirus DNA. J Clin Microbiol (1991) 2.19
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Physical map of the BK virus genome. J Virol (1975) 2.18
Recovery of SV40 virus with genetic markers of original inducing virus from SV40-transformed mouse cells. Virology (1968) 2.15
The effect of interferon on SV-40 T antigen production in SV-40-transformed cells. Virology (1967) 2.13
Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proc Natl Acad Sci U S A (1992) 2.10
The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J Biol Chem (1998) 2.07
Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc Natl Acad Sci U S A (1996) 2.06
Suppression of cellular proliferation by the papillomavirus E2 protein. J Virol (1995) 2.05
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Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. J Biol Chem (1999) 2.02
Functional analysis of E2-mediated repression of the HPV18 P105 promoter. New Biol (1991) 2.02
Isolation of papovavirus from brain tumor and urine of a patient with Wiskott-Aldrich syndrome. J Natl Cancer Inst (1974) 2.00
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Site of host restriction of simian virus 40 mutants in an established African green monkey kidney cell line. J Virol (1969) 1.86
Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Mol Cell (2000) 1.86
Polyoma T antigen synthesis by temperature-sensitive mutants of polyoma virus. Virology (1972) 1.84
Transformation of hamster kidney cells by BK papovavirus DNA. J Virol (1975) 1.81
Characterization of human papovavirus BK DNA. J Virol (1975) 1.81
Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40. Proc Natl Acad Sci U S A (1975) 1.81
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A (1995) 1.81
Comparison of two human papovaviruses with simian virus 40 by structural protein and antigenic analysis. J Virol (1974) 1.76
Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions. J Virol (1996) 1.76
The genetics of bovine papillomavirus type 1. Annu Rev Genet (1988) 1.75
Hamster ascitic fluids containing complement-fixing antibody against virus-induced tumor antigens. Proc Soc Exp Biol Med (1965) 1.74
Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways. EMBO J (2000) 1.73
Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells. J Virol (2000) 1.71
Conserved polynucleotide sequences among the genomes of papillomaviruses. J Virol (1979) 1.70
Bovine papillomavirus type 1 E1 replication-defective mutants are altered in their transcriptional regulation. J Virol (1988) 1.67
Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1. J Virol (1989) 1.65
Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants. J Virol (1990) 1.65
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. J Biol Chem (1998) 1.63
Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination. Proc Natl Acad Sci U S A (1999) 1.63
Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products. Cancer Surv (1992) 1.63
The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation. EMBO J (1988) 1.61