Published in Cell on December 17, 1993
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell (2001) 6.39
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev (1998) 5.20
Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1996) 3.85
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases. Proc Natl Acad Sci U S A (2007) 3.44
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J (1998) 3.09
Trm9-catalyzed tRNA modifications link translation to the DNA damage response. Mol Cell (2007) 2.94
The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage. EMBO J (2001) 2.80
The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A (2002) 2.76
A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci U S A (1999) 2.51
Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae. Mol Cell Biol (1997) 2.46
Break-induced replication is highly inaccurate. PLoS Biol (2011) 2.45
Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways. J Cell Sci (2000) 2.37
Replication in hydroxyurea: it's a matter of time. Mol Cell Biol (2007) 2.35
Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J (1998) 2.34
RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation. EMBO J (1998) 2.32
Inviability of a DNA2 deletion mutant is due to the DNA damage checkpoint. Cell Cycle (2011) 2.25
Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways. Proc Natl Acad Sci U S A (2003) 2.24
Asf1 links Rad53 to control of chromatin assembly. Genes Dev (2001) 2.16
Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J (2000) 2.15
Mitotic DNA damage and replication checkpoints in yeast. Curr Opin Cell Biol (1998) 2.11
RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. EMBO J (1999) 2.05
A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription. EMBO J (1996) 1.99
DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints. Mol Cell Biol (2000) 1.98
Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 1.97
Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol Cell (2008) 1.94
Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional induction after DNA damage and implications for function. Mol Biol Cell (1996) 1.93
Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. Mol Cell Biol (1997) 1.75
Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein. Genes Dev (1998) 1.72
Analysis of RIM11, a yeast protein kinase that phosphorylates the meiotic activator IME1. Mol Cell Biol (1994) 1.70
NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.59
A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants. Genetics (1999) 1.55
Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality. Mol Cell Biol (2000) 1.52
A role for DNA primase in coupling DNA replication to DNA damage response. EMBO J (1997) 1.48
Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain. Proc Natl Acad Sci U S A (1999) 1.47
Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.46
A proteome-wide analysis of kinase-substrate network in the DNA damage response. J Biol Chem (2010) 1.46
Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol Cell Biol (2003) 1.42
Genetic interaction of RAD53 protein kinase with histones is important for DNA replication. Cell Cycle (2010) 1.40
Mutation of the gene encoding protein kinase C 1 stimulates mitotic recombination in Saccharomyces cerevisiae. Mol Cell Biol (1994) 1.38
Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol (2003) 1.37
Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1997) 1.36
Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. EMBO J (2012) 1.35
The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev (2001) 1.34
Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress. Mol Biol Cell (2004) 1.32
Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response. J Biol Chem (2009) 1.31
DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet (2008) 1.31
Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae. Genetics (2006) 1.30
Global gene expression responses of fission yeast to ionizing radiation. Mol Biol Cell (2003) 1.30
Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. J Biol Chem (2006) 1.28
SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I. Proc Natl Acad Sci U S A (1995) 1.21
Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae. Mol Cell Biol (2005) 1.21
DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. Nucleic Acids Res (2005) 1.17
Surviving chromosome replication: the many roles of the S-phase checkpoint pathway. Philos Trans R Soc Lond B Biol Sci (2011) 1.17
DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1. EMBO J (2012) 1.17
Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes. EMBO J (2012) 1.16
Histone H3 K56 hyperacetylation perturbs replisomes and causes DNA damage. Genetics (2008) 1.16
Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.16
The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics (2000) 1.14
The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. Nucleic Acids Res (2010) 1.12
Chromosome Duplication in Saccharomyces cerevisiae. Genetics (2016) 1.11
DNA damage checkpoints inhibit mitotic exit by two different mechanisms. Mol Cell Biol (2007) 1.10
Multicellular stalk-like structures in Saccharomyces cerevisiae. J Bacteriol (1998) 1.09
Role of UME6 in transcriptional regulation of a DNA repair gene in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.09
Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun (2014) 1.08
Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Eukaryot Cell (2003) 1.07
The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint. DNA Repair (Amst) (2006) 1.04
Regulation of histone deposition proteins Asf1/Hir1 by multiple DNA damage checkpoint kinases in Saccharomyces cerevisiae. Genetics (2005) 1.04
Derepression of DNA damage-regulated genes requires yeast TAF(II)s. EMBO J (2000) 1.04
Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae. Genetics (2004) 1.03
Topology and control of the cell-cycle-regulated transcriptional circuitry. Genetics (2014) 1.03
Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) (2012) 1.02
Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation. BMC Genomics (2006) 1.02
Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools. PLoS Genet (2011) 1.02
Induction of S. cerevisiae filamentous differentiation by slowed DNA synthesis involves Mec1, Rad53 and Swe1 checkpoint proteins. Mol Biol Cell (2003) 1.00
Radiosensitive and mitotic recombination phenotypes of the Saccharomyces cerevisiae dun1 mutant defective in DNA damage-inducible gene expression. Genetics (1999) 0.99
Intersection of ChIP and FLIP, genomic methods to study the dynamics of the cohesin proteins. Chromosome Res (2009) 0.98
A role for Saccharomyces cerevisiae Chk1p in the response to replication blocks. Mol Biol Cell (2004) 0.98
A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Mol Biol Cell (2004) 0.95
Arabidopsis thaliana mutants altered in homologous recombination. Proc Natl Acad Sci U S A (1997) 0.94
Fission yeast Iec1-ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism. Mol Cell Biol (2009) 0.94
The DNA damage checkpoint response to replication stress: A Game of Forks. Front Genet (2013) 0.94
Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants. Nucleic Acids Res (2009) 0.94
Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae. Genetics (2000) 0.93
The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. Genetics (2001) 0.92
Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions. EMBO J (2015) 0.90
Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res (2002) 0.90
Promoter elements of the PHR1 gene of Saccharomyces cerevisiae and their roles in the response to DNA damage. Nucleic Acids Res (1995) 0.90
Inducible growth arrest: new mechanistic insights. Proc Natl Acad Sci U S A (1994) 0.88
Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes. Nucleic Acids Res (2006) 0.88
Promoter binding by the Adr1 transcriptional activator may be regulated by phosphorylation in the DNA-binding region. PLoS One (2008) 0.87
Pdr3 is required for DNA damage induction of MAG1 and DDI1 via a bi-directional promoter element. Nucleic Acids Res (2004) 0.87
Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast. Genetics (2013) 0.87
Apurinic/apyrimidinic (AP) endonuclease from Dictyostelium discoideum: cloning, nucleotide sequence and induction by sublethal levels of DNA damaging agents. Nucleic Acids Res (1996) 0.87
dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants. Proc Natl Acad Sci U S A (2015) 0.86
Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism. Proc Natl Acad Sci U S A (2009) 0.85
A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1. Nucleic Acids Res (2015) 0.84
MLH1 deficiency enhances tumor cell sensitivity to ganciclovir. Cancer Gene Ther (2009) 0.84
Cyclin regulation by the s phase checkpoint. J Biol Chem (2010) 0.84
UV irradiation causes the loss of viable mitotic recombinants in Schizosaccharomyces pombe cells lacking the G(2)/M DNA damage checkpoint. Genetics (2002) 0.83
Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways. Nucleic Acids Res (2006) 0.83
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell (1993) 33.20
The DNA damage response: putting checkpoints in perspective. Nature (2000) 19.07
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev (1993) 17.09
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell (1995) 12.39
Site-directed insertion and deletion mutagenesis with cloned fragments in Escherichia coli. J Bacteriol (1985) 12.25
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell (1997) 11.62
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev (2000) 11.49
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell (1996) 11.22
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science (1998) 8.74
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science (1996) 8.71
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science (1997) 8.24
DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science (2000) 7.85
ATR and ATRIP: partners in checkpoint signaling. Science (2001) 7.58
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev (2000) 7.29
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell (1994) 7.05
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science (1999) 6.93
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev (1999) 6.56
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell (2001) 6.39
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science (1999) 6.38
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science (2001) 6.29
Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell (1995) 6.08
p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science (1995) 6.01
Transcriptional regulation and function during the human cell cycle. Nat Genet (2001) 5.89
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A (2000) 5.64
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell (1998) 5.37
Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli. J Mol Biol (1983) 5.24
The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev (1994) 5.20
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev (1998) 5.20
Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol (2001) 5.05
DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint. Cell (1995) 4.90
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature (1993) 4.88
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev (1995) 4.87
Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome. Nature (1997) 4.82
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science (1999) 4.65
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science (1999) 4.61
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature (2000) 4.52
Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell (1995) 4.48
The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes. Curr Biol (1998) 4.14
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis. Nature (1996) 4.05
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev (2000) 3.86
Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions. Mol Cell Biol (1997) 3.77
A family of mammalian F-box proteins. Curr Biol (1999) 3.68
How the cyclin became a cyclin: regulated proteolysis in the cell cycle. Cell (1999) 3.34
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell (1999) 3.19
Specific association between the human DNA repair proteins XPA and ERCC1. Proc Natl Acad Sci U S A (1994) 3.19
umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. Proc Natl Acad Sci U S A (1985) 3.14
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A (1994) 3.03
p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev (1999) 2.58
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat Genet (2000) 2.53
RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae. Genes Dev (1996) 2.53
Cdk inhibitors in development and cancer. Curr Opin Genet Dev (1996) 2.48
Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae. Mol Cell Biol (1997) 2.46
Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev (1998) 2.39
Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell (2001) 2.33
Isolation and characterization of Tn5 insertion mutations in the lexA gene of Escherichia coli. J Bacteriol (1983) 2.24
Gene identification using the yeast two-hybrid system. Methods Enzymol (1996) 2.20
Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15. Proc Natl Acad Sci U S A (1996) 2.17
Asf1 links Rad53 to control of chromatin assembly. Genes Dev (2001) 2.16
Dominant genetics using a yeast genomic library under the control of a strong inducible promoter. Proc Natl Acad Sci U S A (1992) 2.14
PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol (1995) 2.05
Finding prospective partners in the library: the two-hybrid system and phage display find a match. Trends Biochem Sci (1995) 2.04
DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1999) 2.00
Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J Virol (1995) 1.95
Direct DNA binding by Brca1. Proc Natl Acad Sci U S A (2001) 1.94
Phasmid vectors for identification of genes by complementation of Escherichia coli mutants. J Bacteriol (1985) 1.84
Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics (1992) 1.84
The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. J Cell Biol (1994) 1.80
New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res (1999) 1.68
The muc genes of pKM101 are induced by DNA damage. J Bacteriol (1983) 1.68
Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome. Am J Hum Genet (1997) 1.58
Gene identification using the yeast two-hybrid system. Methods Enzymol (1997) 1.53
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome. Genes Dev (1999) 1.51
Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53. FEBS Lett (1995) 1.49
Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev (2001) 1.40
Human cyclin F. EMBO J (1994) 1.39
The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit. Curr Biol (2000) 1.36
The role of Cdk7 in CAK function, a retro-retrospective. Genes Dev (1998) 1.34
G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts. Curr Biol (1998) 1.28
Gene targeting at the human CD4 locus by epitope addition. Genes Dev (1990) 1.27
The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment. J Bacteriol (1996) 1.27
Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells. Genetics (1997) 1.25
Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast. J Biol Chem (1995) 1.23
Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity. Mol Cell Biol (1998) 1.22
Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments. Proc Natl Acad Sci U S A (1995) 1.19
Isolation of temperature-sensitive diphtheria toxins in yeast and their effects on Drosophila cells. Development (1992) 1.17
p53 sends nucleotides to repair DNA. Nature (2000) 1.16
Dissecting cancer pathways and vulnerabilities with RNAi. Cold Spring Harb Symp Quant Biol (2005) 1.15
Selective maternal-allele loss in human lung cancers of the maternally expressed p57KIP2 gene at 11p15.5. Oncogene (1996) 1.13
Interactions among vertebrate helix-loop-helix proteins in yeast using the two-hybrid system. J Biol Chem (1993) 1.11
A family of vectors that facilitate transposon and insertional mutagenesis of cloned genes in yeast. Yeast (1994) 1.08
PAT1, an evolutionarily conserved acetyltransferase homologue, is required for multiple steps in the cell cycle. Genes Cells (1996) 1.07
In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res (1995) 1.04
Amplification of cyclin genes in colorectal carcinomas. Cancer Res (1993) 1.04
Rapid construction of recombinant DNA by the univector plasmid-fusion system. Methods Enzymol (2000) 1.03
Mitotic treasures in the nucleolus. Nature (1999) 0.99
Analysis of budding yeast kinases controlled by DNA damage. Methods Enzymol (1997) 0.95
The cellular chamber of doom. Sci Am (2001) 0.92
Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli. FEBS Lett (1994) 0.91
Purification and analysis of CIP/KIP proteins. Methods Enzymol (1997) 0.90
Stopped for repairs. Bioessays (1995) 0.89