I M Verma

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996 28.95
2 Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 1996 12.23
3 Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 1996 9.15
4 Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature 1985 8.36
5 Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene. Mol Cell Biol 1985 7.49
6 The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J Virol 1996 6.62
7 Development of a self-inactivating lentivirus vector. J Virol 1998 6.60
8 Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science 1999 6.20
9 FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J Virol 1982 6.11
10 Gene therapy -- promises, problems and prospects. Nature 1997 6.02
11 Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell 1983 5.79
12 Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 1990 5.59
13 c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell 1984 5.55
14 Nucleotide sequence of the genome of a murine sarcoma virus. Cell 1981 5.48
15 Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature 1988 5.18
16 Viral and cellular fos proteins: a comparative analysis. Cell 1984 4.89
17 Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science 1984 4.87
18 Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus. Nature 1986 4.70
19 Expression of cellular oncogenes in human malignancies. Science 1984 4.48
20 Differential expression of cellular oncogenes during pre- and postnatal development of the mouse. Nature 1982 4.44
21 Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. Proc Natl Acad Sci U S A 1983 4.38
22 Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet 1997 4.26
23 The reverse transcriptase. Biochim Biophys Acta 1977 4.16
24 Transcriptional autoregulation of the proto-oncogene fos. Nature 1988 4.10
25 Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site. J Virol 1982 4.06
26 Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus. Nature 1981 4.05
27 In vitro synthesis of DNA complementary to rabbit reticulocyte 10S RNA. Nat New Biol 1972 4.01
28 Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci U S A 1995 3.90
29 fos-associated cellular p39 is related to nuclear transcription factor AP-1. Cell 1988 3.82
30 Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation. Cell 1985 3.81
31 Transcriptional activation by BRCA1. Nature 1996 3.64
32 Functional antagonism between c-Jun and MyoD proteins: a direct physical association. Cell 1992 3.55
33 Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences. Proc Natl Acad Sci U S A 1980 3.53
34 The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation. Genes Dev 1991 3.52
35 Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain. Nature 1988 3.43
36 Analysis of the env gene of a molecularly cloned and biologically active Moloney mink cell focus-forming proviral DNA. J Virol 1982 3.40
37 Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci U S A 1997 3.40
38 Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J Virol 1997 3.37
39 Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H. J Virol 1975 3.31
40 A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT. Proc Natl Acad Sci U S A 1983 3.31
41 Covalently linked RNA-DNA molecule as initial product of RNA tumour virus DNA polymerase. Nat New Biol 1971 3.27
42 I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family. Cell 1992 3.25
43 c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. Proc Natl Acad Sci U S A 1988 3.24
44 Autoregulation of I kappa B alpha activity. Proc Natl Acad Sci U S A 1994 3.24
45 Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci U S A 2001 3.24
46 Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science 1999 3.10
47 Two base changes restore infectivity to a noninfectious molecular clone of Moloney murine leukemia virus (pMLV-1). J Virol 1984 3.09
48 Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene. Proc Natl Acad Sci U S A 1985 2.95
49 Regulated mRNA stability. Annu Rev Genet 1990 2.93
50 IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev 1999 2.92
51 Nucleotide sequence of Moloney leukemia virus: 3' end reveals details of replications, analogy to bacterial transposons, and an unexpected gene. Proc Natl Acad Sci U S A 1980 2.90
52 Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein. Mol Cell Biol 1985 2.86
53 Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci U S A 1991 2.85
54 Nuclear proto-oncogenes fos and jun. Annu Rev Cell Biol 1990 2.82
55 Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses. J Virol 1978 2.79
56 Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science 1984 2.75
57 Induction of the proto-oncogene fos by nerve growth factor. Proc Natl Acad Sci U S A 1985 2.74
58 M-MuLV-induced leukemogenesis: integration and structure of recombinant proviruses in tumors. Cell 1981 2.65
59 c-rel activates but v-rel suppresses transcription from kappa B sites. Proc Natl Acad Sci U S A 1991 2.65
60 Gene therapy: trials and tribulations. Nat Rev Genet 2000 2.62
61 Studies on the reverse transcriptase of RNA tumor viruses. Structural relatedness of two subunits of avian RNA tumor viruses. Proc Natl Acad Sci U S A 1974 2.60
62 Cationic liposome-mediated RNA transfection. Proc Natl Acad Sci U S A 1989 2.55
63 Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells. Mol Cell Biol 1983 2.53
64 Expression of a retrovirus encoding human HPRT in mice. Science 1984 2.48
65 Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A 2001 2.48
66 The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Mol Cell Biol 1990 2.47
67 Modification of fos proteins: phosphorylation of c-fos, but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum. Mol Cell Biol 1987 2.40
68 Identification of a transcriptional enhancer element upstream from the proto-oncogene fos. Science 1985 2.39
69 Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element. Genes Dev 1988 2.38
70 mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol Cell Biol 1990 2.38
71 Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants. Proc Natl Acad Sci U S A 1991 2.34
72 Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo. Proc Natl Acad Sci U S A 1992 2.30
73 Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity. Proc Natl Acad Sci U S A 1992 2.29
74 Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus. Cell 1982 2.27
75 A factor IX-deficient mouse model for hemophilia B gene therapy. Proc Natl Acad Sci U S A 1997 2.22
76 Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA. Proc Natl Acad Sci U S A 1981 2.16
77 Transcription of c-onc genes c-rasKi and c-fms during mouse development. Mol Cell Biol 1983 2.14
78 Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B. Proc Natl Acad Sci U S A 1994 2.12
79 Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver. Mol Ther 2000 2.12
80 Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. EMBO J 1990 2.11
81 Molecular cloning of unintegrated and a portion of integrated moloney murine leukemia viral DNA in bacteriophage lambda. J Virol 1980 2.10
82 Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb. Nature 1998 2.08
83 Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion. EMBO J 1983 2.08
84 Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins. Genes Dev 1989 2.06
85 Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol 2000 2.04
86 BRCA1 is a cell cycle-regulated nuclear phosphoprotein. Proc Natl Acad Sci U S A 1997 2.02
87 Identification and molecular cloning of Moloney mouse sarcoma virus-specific sequences from uninfected mouse cells. Proc Natl Acad Sci U S A 1980 1.98
88 Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev 2000 1.96
89 Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B. Nature 1993 1.94
90 Sustained correction of bleeding disorder in hemophilia B mice by gene therapy. Proc Natl Acad Sci U S A 1999 1.90
91 Size analysis and relationship of murine leukemia virus-specific mRNA's: evidence for transposition of sequences during synthesis and processing of subgenomic mRNA. J Virol 1978 1.90
92 DNA polymerase activity from two temperature-sensitive mutants of Rous sarcoma virus is thermolabile. Nature 1974 1.90
93 Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation. Proc Natl Acad Sci U S A 1994 1.89
94 c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages. Cell 1986 1.87
95 Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions. J Virol 1975 1.87
96 Studies on reverse transcriptase of RNA tumor viruses. I. Localization of thermolabile DNA polymerase and RNase H activities on one polypeptide. J Virol 1975 1.84
97 Inhibition of TNF-induced apoptosis by NF-kappa B. Trends Cell Biol 1998 1.84
98 Rel/NF-kappa B/I kappa B story. Adv Cancer Res 1995 1.83
99 Modulation of c-fos gene transcription by negative and positive cellular factors. Nature 1987 1.83
100 Gene therapy: promises and problems. Annu Rev Genomics Hum Genet 2001 1.82
101 Phosphorylation of the C terminus of Fos protein is required for transcriptional transrepression of the c-fos promoter. Nature 1990 1.81
102 An alternative approach to somatic cell gene therapy. Proc Natl Acad Sci U S A 1988 1.81
103 Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery. Proc Natl Acad Sci U S A 1995 1.80
104 Infectious and selectable retrovirus containing an inducible rat growth hormone minigene. Science 1984 1.80
105 Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2. Proc Natl Acad Sci U S A 2000 1.76
106 Purification of the RNA-directed DNA polymerase from avian myeloblastosis virus and its assay with polynucleotide templates. Methods Enzymol 1974 1.75
107 Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses. Mol Cell Biol 1987 1.73
108 Reverse transcriptase of RNA tumor viruses. V. In vitro proteolysis of reverse transcriptase from avian myeloblastosis virus and isolation of a polypeptide manifesting only RNase H activity. J Virol 1978 1.72
109 Heteroduplex analysis of the sequence relationships between the genomes of Kirsten and Harvey sarcoma viruses, their respective parental murine leukemia viruses, and the rat endogenous 30S RNA. J Virol 1979 1.70
110 Genome organization of RNA tumor viruses. I. In vitro synthesis of full-genome-length single-stranded and double-stranded viral DNA transcripts. J Virol 1978 1.68
111 Molecular cloning of unintegrated Moloney mouse sarcoma virus DNA in bacteriophage lambda. Proc Natl Acad Sci U S A 1980 1.68
112 Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines. Mol Cell Biol 1994 1.67
113 Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha. Mol Cell Biol 1996 1.67
114 Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer. J Virol 1999 1.64
115 Elements in the long terminal repeat of murine retroviruses enhance stable transformation by thymidine kinase gene. Nucleic Acids Res 1983 1.63
116 Immunological defects in mice with a targeted disruption in Bcl-3. Genes Dev 1997 1.60
117 Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proc Natl Acad Sci U S A 1990 1.60
118 ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun. Mol Cell Biol 1989 1.59
119 Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction. J Biol Chem 2001 1.56
120 FBR murine osteosarcoma virus. I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product. Virology 1984 1.55
121 Genome organization of RNA tumor viruses II. Physical maps of in vitro-synthesized Moloney murine leukemia virus double-stranded DNA by restriction endonucleases. J Virol 1978 1.55
122 Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. Proc Natl Acad Sci U S A 1999 1.54
123 An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins. Proc Natl Acad Sci U S A 1991 1.54
124 Tissue and cell type-specific expression of two human c-onc genes. Nature 1983 1.53
125 FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes. Virology 1984 1.53
126 Analysis of transforming gene products from Moloney murine sarcoma virus. Cell 1981 1.51
127 A packaging cell line for lentivirus vectors. J Virol 1999 1.48
128 Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha. J Biol Chem 2000 1.47
129 LFG: an anti-apoptotic gene that provides protection from Fas-mediated cell death. Proc Natl Acad Sci U S A 1999 1.47
130 Proto-oncogene expression in regenerating liver is simulated in cultures of primary adult rat hepatocytes. J Biol Chem 1986 1.44
131 Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase. J Virol 1974 1.43
132 Efficient insertion of genes into the mouse germ line via retroviral vectors. Proc Natl Acad Sci U S A 1985 1.42
133 CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc Natl Acad Sci U S A 2000 1.41
134 Constitutive phosphorylation of I kappa B alpha by casein kinase II. Proc Natl Acad Sci U S A 1995 1.41
135 Cross-talk in signal transduction: TPA-inducible factor jun/AP-1 activates cAMP-responsive enhancer elements. Oncogene 1990 1.40
136 Lentiviral vectors: regulated gene expression. Mol Ther 2000 1.39
137 The proto-oncogene bcl-3 encodes an I kappa B protein. Genes Dev 1992 1.38
138 Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene 2011 1.38
139 Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Mol Ther 2001 1.37
140 Expression of cellular oncogenes. Curr Top Microbiol Immunol 1984 1.36
141 Genome organization of retroviruses. VI. Heteroduplex analysis of ecotropic and xenotropic sequences of moloney mink cell focus-inducing viral RNA obtained from either a cloned isolate or a thymoma cell line. J Virol 1979 1.33
142 Regulation of beta-catenin function by the IkappaB kinases. J Biol Chem 2001 1.32
143 Role of the subunits of the avian RNA tumor virus reverse transcriptase. Cold Spring Harb Symp Quant Biol 1975 1.30
144 BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site. Mol Cell Biol 1999 1.29
145 Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs. Proc Natl Acad Sci U S A 1990 1.28
146 Nucleotide sequences of human globin messenger RNA. Proc Natl Acad Sci U S A 1974 1.26
147 Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging. Mol Ther 2001 1.25
148 Lentiviral vectors. Adv Virus Res 2000 1.22
149 Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts. Mol Cell Biol 1989 1.22
150 Genome organization of retroviruses IX. Analysis of the genomes of Friend spleen focus-forming (F-SFFV) and helper murine leukemia viruses by heteroduplex-formation. Virology 1980 1.22
151 Nucleotide sequences of human globin messenger RNA. Ann N Y Acad Sci 1974 1.22
152 Characterization of "early" temperature-sensitive mutants of avian sarcoma viruses: biological properties, thermolability of reverse transcriptase in vitro, and synthesis of viral DNA in infected cells. Virology 1976 1.22
153 NF-kappaB-mediated inhibition of apoptosis is required for encephalomyocarditis virus virulence: a mechanism of resistance in p50 knockout mice. J Virol 1998 1.20
154 Homology among oncogenes. Curr Top Microbiol Immunol 1986 1.19
155 Human c-fos oncogene mapped within chromosomal region 14q21----q31. Proc Natl Acad Sci U S A 1984 1.19
156 Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. Proc Natl Acad Sci U S A 1982 1.18
157 Trans-dominant negative mutants of Fos and Jun. Proc Natl Acad Sci U S A 1990 1.18
158 Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required. Mol Cell Biol 1996 1.17
159 Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains. Genes Dev 1992 1.16
160 Positive control mutations in the MyoD basic region fail to show cooperative DNA binding and transcriptional activation in vitro. Proc Natl Acad Sci U S A 1994 1.16
161 Detection of fos protein during osteogenesis by monoclonal antibodies. Mol Cell Biol 1988 1.15
162 Removal of an mRNA destabilizing element correlates with the increased oncogenicity of proto-oncogene fos. Oncogene Res 1989 1.13
163 Differential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytes. Mol Cell Biol 1989 1.13
164 Gene regulation by tyrosine kinases: src protein activates various promoters, including c-fos. Mol Cell Biol 1989 1.11
165 From c-fos to v-fos. Nature 1984 1.11
166 NF-kappaB and the regulation of hematopoiesis. Cell Death Differ 2006 1.10
167 Genome organization of retroviruses. VII. Infection by double-stranded DNA synthesized in vitro from Moloney murine leukemia virus generates a virus indistinguishable from the original virus used in reverse transcription. Virology 1980 1.10
168 Mitochondrial ribosomal RNA from Aspergillus nidulans: characterization of a novel molecular species. J Mol Biol 1970 1.10
169 Domain swapping reveals the modular nature of Fos, Jun, and CREB proteins. Mol Cell Biol 1990 1.09
170 Genome organization of retroviruses. V. In vitro-synthesized Moloney murine leukemia viral DNA has long terminal redundancy. J Virol 1980 1.09
171 Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha. Proc Natl Acad Sci U S A 1997 1.08
172 Transformation by Fos proteins requires a C-terminal transactivation domain. Mol Cell Biol 1993 1.06
173 Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes. Proc Natl Acad Sci U S A 1988 1.02
174 Towards gene therapy for hemophilia B. Mol Biol Med 1987 1.02
175 Proposed NF-kappa B/I kappa B family nomenclature. Genes Dev 1993 1.02
176 Diverse molecular mechanisms of inhibition of NF-kappa B/DNA binding complexes by I kappa B proteins. Gene Expr 1993 1.01
177 Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line. Proc Natl Acad Sci U S A 1993 1.01
178 Signal transduction: the nuclear target. Curr Opin Cell Biol 1992 1.00
179 Applications of gene therapy to the CNS. Hum Mol Genet 1996 1.00
180 Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity. J Virol 1985 1.00
181 Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential. Mol Cell Biol 1992 0.99
182 Opportunities for the use of lentiviral vectors in human gene therapy. Curr Top Microbiol Immunol 2002 0.97
183 Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis. Hum Gene Ther 1998 0.96
184 The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein. Gene Expr 1993 0.96
185 fos and jun interaction: the role of the leucine zipper. Int J Cancer Suppl 1989 0.95
186 Synthesis of DNA complementary to 14S calf lens crystallin messenger RNA by reverse transcriptase. Biochem Biophys Res Commun 1973 0.95
187 Direct gene transfer to the liver with herpes simplex virus type 1 vectors: transient production of physiologically relevant levels of circulating factor IX. New Biol 1992 0.95
188 A tumultuous year for gene therapy. Mol Ther 2000 0.94
189 Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions. Nucleic Acids Res 1982 0.94
190 Mammalian retrovirus-associated RNase H is virus coded. J Virol 1978 0.93
191 Regulation of proto-oncogene fos: a paradigm for early response genes. Cold Spring Harb Symp Quant Biol 1988 0.93
192 Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses. Proc Natl Acad Sci U S A 1990 0.93
193 Circulating human or canine factor IX from retrovirally transduced primary myoblasts and established myoblast cell lines grafted into murine skeletal muscle. Somat Cell Mol Genet 1992 0.93
194 Expression of FBJ-MSV oncogene (fos) product in bacteria. Virology 1983 0.92
195 Proto-oncogene FosB: the amino terminus encodes a regulatory function required for transformation. Mol Cell Biol 1993 0.91
196 Identification of a nuclear targeting sequence in the Fos protein. Oncogene 1991 0.91
197 Bcl-xL protects adult septal cholinergic neurons from axotomized cell death. Proc Natl Acad Sci U S A 1998 0.90
198 CREB represses transcription of fos promoter: role of phosphorylation. Gene Expr 1991 0.88
199 Transformation by Jun: requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos. Oncogene 1992 0.88
200 Retroviral vectors for persistent expression in vivo. Curr Opin Biotechnol 1992 0.87
201 Retrovirus-mediated gene transfer into embryonal carcinoma and hemopoietic stem cells: expression from a hybrid long terminal repeat. Gene 1989 0.86
202 Characterization and purification of human fos protein generated in insect cells with a baculoviral expression vector. J Virol 1990 0.86
203 Globin messenger RNA in the thalassemia syndromes. Ann N Y Acad Sci 1974 0.85
204 Association of nuclear oncoproteins fos and jun. Curr Opin Cell Biol 1989 0.85
205 Cationic liposome-mediated RNA transfection. Methods Enzymol 1993 0.85
206 Physico-chemical properties of mitochondrial ribosomal RNA from fungi. Eur J Biochem 1971 0.85
207 Human fos gene. Cold Spring Harb Symp Quant Biol 1986 0.85
208 Genome organization of retroviruses. III. Restriction endonuclease cleavage maps of mouse sarcoma virus double-stranded DNA synthesized in vitro. Nucleic Acids Res 1979 0.84
209 Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant. Mol Cell Biol 1990 0.84
210 Proto-oncogene fos is expressed during development, differentiation, and growth. Cold Spring Harb Symp Quant Biol 1985 0.84
211 Size determination of mitochondrial ribosomal RNA from Aspergillus nidulans by electron microscopy. J Mol Biol 1970 0.84
212 Retroviral vector targeting to human immunodeficiency virus type 1-infected cells by receptor pseudotyping. J Virol 2000 0.84
213 Kappa B enhancer-binding complexes that do not contain NF-kappa B are developmentally regulated in mammalian brain. Proc Natl Acad Sci U S A 1994 0.83
214 Developmental expression of the Xenopus laevis fos protooncogene. Cell Growth Differ 1990 0.82
215 Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells. Mol Endocrinol 1987 0.82
216 Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. Biochemistry 1974 0.82
217 Genome organization of retroviruses. VIII. Nonproducer cell lines of mouse fibroblasts transformed by Moloney murine sarcoma virus DNA synthesized in vitro. Virology 1980 0.82
218 Piecing together more efficient gene expression. Nat Biotechnol 1999 0.79
219 Optical absorbance properties of mitochondrial ribosomal RNA. Biochem Biophys Res Commun 1971 0.78
220 Genome and gene therapy. Mol Ther 2000 0.78
221 Heteroduplex analysis of the RNA of clone 3 Moloney murine sarcoma virus. J Virol 1979 0.77
222 Long-term expression of a retrovirally introduced beta-galactosidase gene in rodent cells implanted in vivo using biodegradable polymer meshes. Somat Cell Mol Genet 1992 0.76
223 Proto-oncogene fos: an inducible multifaceted gene. Symp Fundam Cancer Res 1986 0.76
224 Expression of the c-fos gene during differentiation. Adv Exp Med Biol 1987 0.76
225 "Green light" for gene transfer. Nat Biotechnol 1996 0.75
226 Gene therapy: public education. Mol Ther 2000 0.75
227 Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants. Cancer 1974 0.75
228 Structural features of growth factor receptors with oncogenic potential. Biochem Soc Symp 1986 0.75
229 Nucleotide sequence of a cloned murine leukemia virus DNA fragment. Cold Spring Harb Symp Quant Biol 1980 0.75
230 Germline gene therapy: yes or no? Mol Ther 2001 0.75
231 A comparison of nucleotide sequences from mitochondrial and cytoplasmic ribosomal RNA of Aspergillus nidulans. Eur J Biochem 1971 0.75
232 Adverse event reporting: essential for science and public trust. Mol Ther 2001 0.75
233 Ultraviolet cross-linking of DNA binding proteins. Methods Enzymol 1995 0.75
234 Proto-oncogene fos expression and post-translational modification. Prog Clin Biol Res 1988 0.75
235 Gene therapy: beyond 2000. Mol Ther 2000 0.75
236 Gene therapy and jurisprudence. Mol Ther 2001 0.75
237 Proto-oncogene fos: factors affecting expression and covalent modification of the gene product. Ann N Y Acad Sci 1987 0.75
238 AIDS: are we doing enough? Mol Ther 2000 0.75
239 Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an associated ribonuclease. Johns Hopkins Med J Suppl 1973 0.75
240 Are the benefits of stem cells being oversold? Mol Ther 2001 0.75
241 Ombudsman or hotline for Gene therapy clinical trials? Mol Ther 2001 0.75
242 Stem cell research: win, win, win by keeping politics out. Mol Ther 2001 0.75
243 Biogenesis of a transforming gene. Mol Biol Rep 1981 0.75
244 Pharma + profits = continued aids epidemic. Mol Ther 2001 0.75
245 Gene therapy: the need for basic science. Mol Ther 2000 0.75
246 Reverse transcriptase is coded for by the viral RNA. Bibl Haematol 1975 0.75
247 Recombinant retroviruses in transgenic mice. Ann N Y Acad Sci 1986 0.75