Published in Virology on October 01, 1976
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration. Proc Natl Acad Sci U S A (1984) 5.81
Genome organization of RNA tumor viruses. I. In vitro synthesis of full-genome-length single-stranded and double-stranded viral DNA transcripts. J Virol (1978) 1.68
Isolation and genetic characterization of temperature-sensitive mutants of vaccinia virus WR. J Virol (1982) 1.54
Virus-coded DNA endonuclease from avian retrovirus. J Virol (1981) 1.45
Interactions of murine leukemia virus core components: characterization of reverse transcriptase packaged in the absence of 70S genomic RNA. J Virol (1977) 1.17
Mammalian retrovirus-associated RNase H is virus coded. J Virol (1978) 0.93
Rous sarcoma virus mutant LA3382 is defective in virion glycoprotein assembly. J Virol (1981) 0.93
Two avian sarcoma virus mutants with defects in the DNA polymerase-RNase H complex. J Virol (1979) 0.86
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (1996) 28.95
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. Cell (1978) 13.33
The molecular biology of the hepatitis B viruses. Annu Rev Biochem (1987) 12.32
Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (1996) 12.23
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein. Cell (1978) 11.17
Correct integration of retroviral DNA in vitro. Cell (1987) 10.73
Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Nature (1988) 10.69
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell (1982) 9.29
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A (1996) 9.15
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas. Nature (1982) 9.12
Form and function of retroviral proviruses. Science (1982) 8.80
A nucleoprotein complex mediates the integration of retroviral DNA. Genes Dev (1989) 8.80
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med (1998) 8.62
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature (1985) 8.36
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc Natl Acad Sci U S A (1989) 8.13
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci U S A (1979) 7.55
Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene. Mol Cell Biol (1985) 7.49
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites. Cell (1978) 7.46
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules. J Virol (1980) 7.37
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region. Cell (1988) 7.14
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc Natl Acad Sci U S A (1983) 7.01
Analysis of avian leukosis virus DNA and RNA in bursal tumours: viral gene expression is not required for maintenance of the tumor state. Cell (1981) 6.98
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol (2000) 6.71
The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J Virol (1996) 6.62
Development of a self-inactivating lentivirus vector. J Virol (1998) 6.60
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell (1988) 6.48
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science (1999) 6.20
Structure and variability of human chromosome ends. Mol Cell Biol (1990) 6.18
FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J Virol (1982) 6.11
Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus. Cell (1986) 6.07
Gene therapy -- promises, problems and prospects. Nature (1997) 6.02
Expression of the Rous sarcoma virus pol gene by ribosomal frameshifting. Science (1985) 5.90
A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration. Proc Natl Acad Sci U S A (1984) 5.81
Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell (1983) 5.79
The molecular genetics of cellular oncogenes. Annu Rev Genet (1984) 5.72
Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as wel as for reverse transcription. Nature (1990) 5.68
Myristylation is required for intracellular transport but not for assembly of D-type retrovirus capsids. J Virol (1987) 5.68
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev (2001) 5.67
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell (1990) 5.59
c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell (1984) 5.55
Nucleotide sequence of the genome of a murine sarcoma virus. Cell (1981) 5.48
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses. Cell (1977) 5.23
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product. Nature (1980) 5.22
Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (1988) 5.18
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. J Mol Biol (1976) 5.07
A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor. Cell (1993) 4.97
Viral and cellular fos proteins: a comparative analysis. Cell (1984) 4.89
Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (1984) 4.87
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus. Nature (1986) 4.70
Retroviruses as mutagens: insertion and excision of a nontransforming provirus alter expression of a resident transforming provirus. Cell (1981) 4.66
Virus-specific DNA in the cytoplasm of avian sarcoma virus-infected cells is a precursor to covalently closed circular viral DNA in the nucleus. J Virol (1978) 4.55
Wnt genes. Cell (1992) 4.55
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell (1983) 4.53
Expression of cellular oncogenes in human malignancies. Science (1984) 4.48
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci U S A (1978) 4.47
Differential expression of cellular oncogenes during pre- and postnatal development of the mouse. Nature (1982) 4.44
A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent. Proc Natl Acad Sci U S A (1994) 4.43
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. Proc Natl Acad Sci U S A (1983) 4.38
Nucleotide sequences at host-proviral junctions for mouse mammary tumour virus. Nature (1981) 4.38
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture. Nature (1985) 4.31
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet (1997) 4.26
Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity. J Virol (1992) 4.20
Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proc Natl Acad Sci U S A (1973) 4.19
A joint produce of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase. Cell (1977) 4.18
The reverse transcriptase. Biochim Biophys Acta (1977) 4.16
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature (1995) 4.14
Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science (1986) 4.12
Transcriptional autoregulation of the proto-oncogene fos. Nature (1988) 4.10
Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site. J Virol (1982) 4.06
Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA. Cell (1977) 4.06
Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus. Nature (1981) 4.05
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. J Mol Biol (1978) 4.04
In vitro synthesis of DNA complementary to rabbit reticulocyte 10S RNA. Nat New Biol (1972) 4.01
Information access. Building a "GenBank" of the published literature. Science (2001) 3.95
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine. J Biol Chem (1980) 3.95
Nucleotide sequence of an infectious molecularly cloned genome of ground squirrel hepatitis virus. J Virol (1984) 3.91
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci U S A (1995) 3.90
Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate. J Biol Chem (1969) 3.86
Two efficient ribosomal frameshifting events are required for synthesis of mouse mammary tumor virus gag-related polyproteins. Proc Natl Acad Sci U S A (1987) 3.84
fos-associated cellular p39 is related to nuclear transcription factor AP-1. Cell (1988) 3.82
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements. Proc Natl Acad Sci U S A (1981) 3.82
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation. Cell (1985) 3.81
A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus. Cell (1990) 3.70
A proline-rich motif (PPPY) in the Gag polyprotein of Mason-Pfizer monkey virus plays a maturation-independent role in virion release. J Virol (1998) 3.69
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev (1998) 3.68
Transcriptional activation by BRCA1. Nature (1996) 3.64
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus. Nature (1975) 3.63
Integration of the DNA of mouse mammary tumor virus in virus-infected normal and neoplastic tissue of the mouse. Cell (1979) 3.63
Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell (1992) 3.60
Genetic lesion in homozygous alpha thalassaemia (hydrops fetalis). Nature (1974) 3.58
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56
Functional antagonism between c-Jun and MyoD proteins: a direct physical association. Cell (1992) 3.55
Mutations in the leucine zipper of the human immunodeficiency virus type 1 transmembrane glycoprotein affect fusion and infectivity. J Virol (1992) 3.54
Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences. Proc Natl Acad Sci U S A (1980) 3.53
The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation. Genes Dev (1991) 3.52
Isolation of a chicken gene that confers susceptibility to infection by subgroup A avian leukosis and sarcoma viruses. J Virol (1993) 3.46