Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria.

PubWeight™: 5.36‹?› | Rank: Top 1%

🔗 View Article (PMC 372912)

Published in Microbiol Rev on June 01, 1993

Authors

R Tam1, M H Saier

Author Affiliations

1: Department of Biology, University of California, San Diego, La Jolla 92093-0116.

Articles citing this

(truncated to the top 100)

Cell biology and molecular basis of denitrification. Microbiol Mol Biol Rev (1997) 13.18

Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm. J Bacteriol (2002) 6.98

Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol Mol Biol Rev (2008) 5.97

A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev (2000) 5.65

Stimulus perception in bacterial signal-transducing histidine kinases. Microbiol Mol Biol Rev (2006) 4.12

Lipoproteins of gram-positive bacteria. J Bacteriol (1995) 3.83

Pneumococcal virulence factors: structure and function. Microbiol Mol Biol Rev (2001) 3.25

Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution. Microbiol Rev (1994) 3.12

Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes. Chem Rev (2009) 2.94

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels. Genome Biol (2004) 2.39

Lmb, a protein with similarities to the LraI adhesin family, mediates attachment of Streptococcus agalactiae to human laminin. Infect Immun (1999) 2.31

Enterococcus faecalis pheromone binding protein, PrgZ, recruits a chromosomal oligopeptide permease system to import sex pheromone cCF10 for induction of conjugation. Proc Natl Acad Sci U S A (1996) 2.27

Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. J Bacteriol (1994) 2.19

Nucleotide sequence of the Streptococcus gordonii PK488 coaggregation adhesin gene, scaA, and ATP-binding cassette. Infect Immun (1994) 2.14

Mutation in the peb1A locus of Campylobacter jejuni reduces interactions with epithelial cells and intestinal colonization of mice. Infect Immun (1998) 2.14

Construction of a fluorescent biosensor family. Protein Sci (2002) 2.07

Molecular genetic analysis of a locus required for resistance to antimicrobial peptides in Salmonella typhimurium. EMBO J (1993) 2.03

Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans. Infect Immun (1999) 1.97

Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Proc Natl Acad Sci U S A (2005) 1.95

Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering. Protein Sci (2005) 1.94

Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins. Proc Natl Acad Sci U S A (2012) 1.89

TRAP transporters: a new family of periplasmic solute transport systems encoded by the dctPQM genes of Rhodobacter capsulatus and by homologs in diverse gram-negative bacteria. J Bacteriol (1997) 1.88

A phylogenomic analysis of the Actinomycetales mce operons. BMC Genomics (2007) 1.88

Posttranslational protein modification in Archaea. Microbiol Mol Biol Rev (2005) 1.86

A specialized version of the HD hydrolase domain implicated in signal transduction. J Mol Microbiol Biotechnol (1999) 1.86

Staphylococcus aureus deficient in lipidation of prelipoproteins is attenuated in growth and immune activation. Infect Immun (2005) 1.76

Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization. Infect Immun (1999) 1.72

Identification and characterization of a Streptococcus pyogenes operon involved in binding of hemoproteins and acquisition of iron. Infect Immun (2003) 1.72

Integrated metatranscriptomic and metagenomic analyses of stratified microbial assemblages in the open ocean. ISME J (2010) 1.72

Enterococcus faecalis antigens in human infections. Infect Immun (1997) 1.66

Molecular identification of an ABC transporter complex for manganese: analysis of a cyanobacterial mutant strain impaired in the photosynthetic oxygen evolution process. EMBO J (1995) 1.58

Archaeal binding protein-dependent ABC transporter: molecular and biochemical analysis of the trehalose/maltose transport system of the hyperthermophilic archaeon Thermococcus litoralis. J Bacteriol (1998) 1.53

Protein secretion and membrane insertion systems in gram-negative bacteria. J Membr Biol (2007) 1.51

Molecular cloning of a 32-kilodalton lipoprotein component of a novel iron-regulated Staphylococcus epidermidis ABC transporter. Infect Immun (1998) 1.51

The signaling helix: a common functional theme in diverse signaling proteins. Biol Direct (2006) 1.46

NikR is a ribbon-helix-helix DNA-binding protein. Protein Sci (1999) 1.45

Dealing with iron: common structural principles in proteins that transport iron and heme. Proc Natl Acad Sci U S A (2003) 1.44

Three different systems participate in L-cystine uptake in Bacillus subtilis. J Bacteriol (2004) 1.40

Three different putative phosphate transport receptors are encoded by the Mycobacterium tuberculosis genome and are present at the surface of Mycobacterium bovis BCG. J Bacteriol (1997) 1.38

A binding-lipoprotein-dependent oligopeptide transport system in Streptococcus gordonii essential for uptake of hexa- and heptapeptides. J Bacteriol (1996) 1.38

Depletion of intestinal phosphate after operative injury activates the virulence of P aeruginosa causing lethal gut-derived sepsis. Surgery (2008) 1.38

Molecular cloning and analysis of a putative siderophore ABC transporter from Staphylococcus aureus. Infect Immun (2000) 1.37

Conversion of a maltose receptor into a zinc biosensor by computational design. Proc Natl Acad Sci U S A (2001) 1.37

Regulation of the alpha-galactosidase activity in Streptococcus pneumoniae: characterization of the raffinose utilization system. Genome Res (1999) 1.35

Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct. Protein Sci (1998) 1.35

Identification and characterization of genes required for biosynthesis and transport of the siderophore vibrioferrin in Vibrio parahaemolyticus. J Bacteriol (2003) 1.34

LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis. EMBO J (2006) 1.31

Identification and characterization of fhuD1 and fhuD2, two genes involved in iron-hydroxamate uptake in Staphylococcus aureus. J Bacteriol (2001) 1.29

Tromp1, a putative rare outer membrane protein, is anchored by an uncleaved signal sequence to the Treponema pallidum cytoplasmic membrane. J Bacteriol (1997) 1.29

Computational design of receptors for an organophosphate surrogate of the nerve agent soman. Proc Natl Acad Sci U S A (2004) 1.29

Protonophore- and pH-insensitive glucose and sucrose accumulation detected by FRET nanosensors in Arabidopsis root tips. Plant J (2008) 1.28

Cellodextrin and laminaribiose ABC transporters in Clostridium thermocellum. J Bacteriol (2008) 1.27

Oligosaccharide binding proteins from Bifidobacterium longum subsp. infantis reveal a preference for host glycans. PLoS One (2011) 1.25

Identification of a DtxR-regulated operon that is essential for siderophore-dependent iron uptake in Corynebacterium diphtheriae. J Bacteriol (2002) 1.25

Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures. Protein Sci (2007) 1.24

Rapid metabolism of glucose detected with FRET glucose nanosensors in epidermal cells and intact roots of Arabidopsis RNA-silencing mutants. Plant Cell (2006) 1.23

Identification of a Treponema denticola OppA homologue that binds host proteins present in the subgingival environment. Infect Immun (2000) 1.23

Characterization of a novel outer membrane hemin-binding protein of Porphyromonas gingivalis. J Bacteriol (2000) 1.23

Characterization of the genes encoding a receptor-like histidine kinase and a cognate response regulator from a biphenyl/polychlorobiphenyl-degrading bacterium, Rhodococcus sp. strain M5. J Bacteriol (1997) 1.22

Influence of divalent cations in protein crystallization. Protein Sci (1995) 1.22

The crystal structure of Zn(II)-free Treponema pallidum TroA, a periplasmic metal-binding protein, reveals a closed conformation. J Bacteriol (2002) 1.21

Characterization of the binding protein-dependent cellobiose and cellotriose transport system of the cellulose degrader Streptomyces reticuli. Appl Environ Microbiol (1999) 1.19

Identification and characterization of SirA, an iron-regulated protein from Staphylococcus aureus. J Bacteriol (1999) 1.19

Crystal structure of the dipeptide binding protein from Escherichia coli involved in active transport and chemotaxis. Protein Sci (1995) 1.19

A di- and tripeptide transport system can supply Listeria monocytogenes Scott A with amino acids essential for growth. Appl Environ Microbiol (1995) 1.18

Molecular characterization of a Campylobacter jejuni lipoprotein with homology to periplasmic siderophore-binding proteins. J Bacteriol (1995) 1.17

Impact of the high-affinity proline permease gene (putP) on the virulence of Staphylococcus aureus in experimental endocarditis. Infect Immun (1999) 1.17

Accessing a hidden conformation of the maltose binding protein using accelerated molecular dynamics. PLoS Comput Biol (2011) 1.16

The bspA locus of Lactobacillus fermentum BR11 encodes an L-cystine uptake system. J Bacteriol (1999) 1.16

Identification and characterization of a basic cell surface-located protein from Lactobacillus fermentum BR11. J Bacteriol (1997) 1.16

Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses. Biochim Biophys Acta (2007) 1.14

Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria. J Biol Chem (2010) 1.14

In silico and transcriptional analysis of carbohydrate uptake systems of Streptomyces coelicolor A3(2). J Bacteriol (2004) 1.14

On the binding mechanism of the peptide receptor of the oligopeptide transport system of Lactococcus lactis. EMBO J (2000) 1.14

Identification of novel pathogenicity loci in Clostridium perfringens strains that cause avian necrotic enteritis. PLoS One (2010) 1.13

Hydrogen bond networks determine emergent mechanical and thermodynamic properties across a protein family. Chem Cent J (2008) 1.12

Mechanistic insights into a novel exporter-importer system of Mycobacterium tuberculosis unravel its role in trafficking of iron. PLoS One (2008) 1.12

Ferrichrome transport in Escherichia coli K-12: altered substrate specificity of mutated periplasmic FhuD and interaction of FhuD with the integral membrane protein FhuB. J Bacteriol (1995) 1.11

A peptide permease mutant of Mycobacterium bovis BCG resistant to the toxic peptides glutathione and S-nitrosoglutathione. Infect Immun (2000) 1.11

Only one of four oligopeptide transport systems mediates nitrogen nutrition in Staphylococcus aureus. J Bacteriol (2007) 1.11

Genetically encoded FRET sensors for visualizing metabolites with subcellular resolution in living cells. Plant Physiol (2005) 1.11

Molecular call and response: the physiology of bacterial small RNAs. Biochim Biophys Acta (2011) 1.10

Computational design of a Zn2+ receptor that controls bacterial gene expression. Proc Natl Acad Sci U S A (2003) 1.09

Overrepresentation of a gene family encoding extracytoplasmic solute receptors in Bordetella. J Bacteriol (2003) 1.09

Lyme disease-causing Borrelia species encode multiple lipoproteins homologous to peptide-binding proteins of ABC-type transporters. Infect Immun (1998) 1.09

The adherence-associated lipoprotein P100, encoded by an opp operon structure, functions as the oligopeptide-binding domain OppA of a putative oligopeptide transport system in Mycoplasma hominis. J Bacteriol (1999) 1.08

Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks. PLoS Pathog (2011) 1.08

Proteogenomic analysis of a thermophilic bacterial consortium adapted to deconstruct switchgrass. PLoS One (2013) 1.08

Sequence relationships between integral inner membrane proteins of binding protein-dependent transport systems: evolution by recurrent gene duplications. Protein Sci (1994) 1.08

Molecular characterization of a high-affinity xylobiose transporter of Streptomyces thermoviolaceus OPC-520 and its transcriptional regulation. J Bacteriol (2004) 1.08

Cellobiose uptake in the hyperthermophilic archaeon Pyrococcus furiosus is mediated by an inducible, high-affinity ABC transporter. J Bacteriol (2001) 1.08

Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections. Infect Immun (2000) 1.07

The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks. Infect Immun (2011) 1.07

Characterization of a Snorhizobium meliloti ATP-binding cassette histidine transporter also involved in betaine and proline uptake. J Bacteriol (2000) 1.07

Sulfate and thiosulfate transport in Escherichia coli K-12: evidence for a functional overlapping of sulfate- and thiosulfate-binding proteins. J Bacteriol (1995) 1.06

Bis-(3'-5')-cyclic dimeric GMP-linked quorum sensing controls swarming in Vibrio parahaemolyticus. Proc Natl Acad Sci U S A (2011) 1.06

alpha-Galactoside uptake in Rhizobium meliloti: isolation and characterization of agpA, a gene encoding a periplasmic binding protein required for melibiose and raffinose utilization. J Bacteriol (1998) 1.06

The sulfur-regulated arylsulfatase gene cluster of Pseudomonas aeruginosa, a new member of the cys regulon. J Bacteriol (2000) 1.05

Extracellular synthesis, specific recognition, and intracellular degradation of cyclomaltodextrins by the hyperthermophilic archaeon Thermococcus sp. strain B1001. J Bacteriol (2001) 1.05

Dynamics and allosteric potential of the AMPA receptor N-terminal domain. EMBO J (2011) 1.05

Articles cited by this

(truncated to the top 100)

Improved tools for biological sequence comparison. Proc Natl Acad Sci U S A (1988) 193.60

A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98

Rapid and sensitive protein similarity searches. Science (1985) 76.83

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science (1989) 40.22

Similar amino acid sequences: chance or common ancestry? Science (1981) 28.87

Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol Rev (1989) 20.50

ABC transporters: from microorganisms to man. Annu Rev Cell Biol (1992) 19.49

Establishing homologies in protein sequences. Methods Enzymol (1983) 15.70

PROSITE: a dictionary of sites and patterns in proteins. Nucleic Acids Res (1991) 9.18

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell (1986) 8.53

Nucleotide sequence of an Escherichia coli chromosomal hemolysin. J Bacteriol (1985) 8.53

PROSITE: a dictionary of sites and patterns in proteins. Nucleic Acids Res (1992) 8.52

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Trends Biochem Sci (1993) 7.14

Signal transduction pathways involving protein phosphorylation in prokaryotes. Annu Rev Biochem (1991) 6.84

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell (1986) 5.51

Los Alamos sequence analysis package for nucleic acids and proteins. Nucleic Acids Res (1982) 5.48

Maltose transport in Escherichia coli K12. A comparison of transport kinetics in wild-type and lambda-resistant mutants as measured by fluorescence quenching. Eur J Biochem (1976) 5.25

DNA sequence of the white locus of Drosophila melanogaster. J Mol Biol (1984) 5.01

Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis. EMBO J (1988) 4.75

Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium. Nature (1982) 4.71

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature (1989) 4.63

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature (1991) 4.50

CHARACTERIZATION OF A SULFATE- AND THIOSULFATE-TRANSPORTING SYSTEM IN SALMONELLA TYPHIMURIUM. J Biol Chem (1964) 4.41

Two-way chemical signaling in Agrobacterium-plant interactions. Microbiol Rev (1992) 4.37

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J (1989) 4.10

A family of bacterial regulators homologous to Gal and Lac repressors. J Biol Chem (1992) 4.07

Genetics of bacterial sporulation. Adv Genet (1976) 4.05

Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family. Mol Microbiol (1990) 4.03

A single amino acid determinant of the membrane localization of lipoproteins in E. coli. Cell (1988) 4.03

Cloning, nucleotide sequence, and characterization of genes encoding the secretion function of the Pasteurella haemolytica leukotoxin determinant. J Bacteriol (1989) 3.98

Transport of sugars and amino acids in bacteria. I. Purification and specificity of the galactose- and leucine-binding proteins. J Biol Chem (1968) 3.94

The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Mol Microbiol (1991) 3.93

Active transport of maltose in Escherichia coli K12. Involvement of a "periplasmic" maltose binding protein. Eur J Biochem (1974) 3.89

Gene regulation by phosphate in enteric bacteria. J Cell Biochem (1993) 3.77

Genetic analysis of protein export in Escherichia coli. Annu Rev Genet (1990) 3.73

Signal transduction in the phosphate regulon of Escherichia coli involves phosphotransfer between PhoR and PhoB proteins. J Mol Biol (1989) 3.56

Progressive alignment and phylogenetic tree construction of protein sequences. Methods Enzymol (1990) 3.55

Nitrogen control of Salmonella typhimurium: co-regulation of synthesis of glutamine synthetase and amino acid transport systems. J Bacteriol (1979) 3.54

Sugars induce the Agrobacterium virulence genes through a periplasmic binding protein and a transmembrane signal protein. Proc Natl Acad Sci U S A (1990) 3.48

The spo0K locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence. J Bacteriol (1991) 3.48

Two systems for the uptake of phosphate in Escherichia coli. J Bacteriol (1977) 3.46

The 2.3-A resolution structure of the maltose- or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis. J Biol Chem (1991) 3.42

Bacterial chemotaxis and the molecular logic of intracellular signal transduction networks. Annu Rev Biophys Biophys Chem (1991) 3.18

Regulation of the phosphate regulon of Escherichia coli. Activation of pstS transcription by PhoB protein in vitro. J Mol Biol (1988) 3.14

Sequences of the malE gene and of its product, the maltose-binding protein of Escherichia coli K12. J Biol Chem (1984) 3.10

Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae. Cell (1982) 3.06

A binding protein-dependent transport system in Streptococcus mutans responsible for multiple sugar metabolism. J Biol Chem (1992) 3.03

Molecular characterization of the oligopeptide permease of Salmonella typhimurium. J Mol Biol (1987) 3.00

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes. Mol Cell Biol (1988) 2.98

Phosphate-specific transport system of Escherichia coli: nucleotide sequence and gene-polypeptide relationships. J Bacteriol (1985) 2.98

Nucleotide sequence of the structural genes for an anion pump. The plasmid-encoded arsenical resistance operon. J Biol Chem (1986) 2.97

Extracellular control of spore formation in Bacillus subtilis. Proc Natl Acad Sci U S A (1988) 2.96

Evidence for a common molecular origin of the capsule gene loci in gram-negative bacteria expressing group II capsular polysaccharides. Mol Microbiol (1991) 2.86

A NEW SYNTHETIC MEDIUM FOR DIPLOCOCCUS PNEUMONIAE, AND ITS USE FOR THE STUDY OF RECIPROCAL TRANSFORMATIONS AT THE AMIA LOCUS. Genetics (1964) 2.84

Cloning and complete nucleotide sequence of the Escherichia coli glutamine permease operon (glnHPQ). Mol Gen Genet (1986) 2.73

Genetic analysis of an MDR-like export system: the secretion of colicin V. EMBO J (1990) 2.71

Purification and properties of a sulfate-binding protein from Salmonella typhimurium. J Biol Chem (1966) 2.69

Purification and properties of a leucine-binding protein from Escherichia coli. J Biol Chem (1968) 2.67

Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B. J Biol Chem (1990) 2.59

Binding protein-dependent transport systems. J Bioenerg Biomembr (1990) 2.53

Protease secretion by Erwinia chrysanthemi: the specific secretion functions are analogous to those of Escherichia coli alpha-haemolysin. EMBO J (1990) 2.51

The bex locus in encapsulated Haemophilus influenzae: a chromosomal region involved in capsule polysaccharide export. Mol Microbiol (1990) 2.49

Capsule loss in H. influenzae type b occurs by recombination-mediated disruption of a gene essential for polysaccharide export. Cell (1988) 2.49

Evidence for high affinity binding-protein dependent transport systems in gram-positive bacteria and in Mycoplasma. EMBO J (1988) 2.47

Anaerobic and leucine-dependent expression of a peptide transport gene in Salmonella typhimurium. J Bacteriol (1984) 2.46

The ndvA gene product of Rhizobium meliloti is required for beta-(1----2)glucan production and has homology to the ATP-binding export protein HlyB. J Bacteriol (1988) 2.45

Genetic recombination in DNA-induced transformation of Pneumococcus. II. Mapping the amiA region. Genetics (1965) 2.41

The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily. J Biol Chem (1990) 2.40

Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences. Proc Natl Acad Sci U S A (1981) 2.37

Involvement of the Escherichia coli phn (psiD) gene cluster in assimilation of phosphorus in the form of phosphonates, phosphite, Pi esters, and Pi. J Bacteriol (1991) 2.33

Sugar-mediated induction of Agrobacterium tumefaciens virulence genes: structural specificity and activities of monosaccharides. J Bacteriol (1990) 2.31

Murein components rescue developmental sporulation of Myxococcus xanthus. J Bacteriol (1982) 2.31

The ami locus of the gram-positive bacterium Streptococcus pneumoniae is similar to binding protein-dependent transport operons of gram-negative bacteria. Mol Microbiol (1990) 2.31

A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin. Proc Natl Acad Sci U S A (1991) 2.28

Nucleotide sequence of the osmoregulatory proU operon of Escherichia coli. J Bacteriol (1989) 2.26

Uptake and catabolism of D-xylose in Salmonella typhimurium LT2. J Bacteriol (1979) 2.26

Uptake of cell wall peptides by Salmonella typhimurium and Escherichia coli. J Bacteriol (1987) 2.18

Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli. J Bacteriol (1989) 2.17

Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. Nat Genet (1992) 2.16

Transport proteins in bacteria: common themes in their design. Science (1992) 2.14

Basic amino acid transport in Escherichia coli. J Biol Chem (1971) 2.13

Export of unprocessed precursor maltose-binding protein to the periplasm of Escherichia coli cells. J Bacteriol (1987) 2.12

Unity in function in the absence of consensus in sequence: role of leader peptides in export. Science (1989) 2.12

Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein. Mol Microbiol (1991) 2.09

Purification of a leucine-specific binding protein from Escherichia coli. Biochem Biophys Res Commun (1970) 2.09

Cloning and characterization of a second member of the mouse mdr gene family. Mol Cell Biol (1988) 2.06

Rates of ligand binding to periplasmic proteins involved in bacterial transport and chemotaxis. J Biol Chem (1983) 2.06

The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genes. Gene (1986) 2.04

Role for [corrected] Agrobacterium tumefaciens ChvA protein in export of beta-1,2-glucan. J Bacteriol (1989) 2.04

Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system. Mol Microbiol (1988) 2.04

Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process. Microbiol Rev (1989) 1.99

Control of expression of Agrobacterium vir genes by synergistic actions of phenolic signal molecules and monosaccharides. Proc Natl Acad Sci U S A (1990) 1.98

Nearest neighbor procedure for relating progressively aligned amino acid sequences. Methods Enzymol (1990) 1.97

Transcriptional regulation of a Bacillus subtilis dipeptide transport operon. Mol Microbiol (1991) 1.92

A novel calcium binding site in the galactose-binding protein of bacterial transport and chemotaxis. Nature (1987) 1.92

The nucleotide sequences of the rbsD, rbsA, and rbsC genes of Escherichia coli K12. J Biol Chem (1986) 1.90

Lipoprotein nature of Bacillus licheniformis membrane penicillinase. Proc Natl Acad Sci U S A (1981) 1.88

Reduction of arsenate to arsenite by the ArsC protein of the arsenic resistance operon of Staphylococcus aureus plasmid pI258. Proc Natl Acad Sci U S A (1992) 1.85

A mycoplasma high-affinity transport system and the in vitro invasiveness of mouse sarcoma cells. EMBO J (1988) 1.80

Identification of two genes, kpsM and kpsT, in region 3 of the polysialic acid gene cluster of Escherichia coli K1. J Bacteriol (1991) 1.77

Articles by these authors

(truncated to the top 100)

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature (2000) 32.30

Major facilitator superfamily. Microbiol Mol Biol Rev (1998) 9.77

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Trends Biochem Sci (1993) 7.14

Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities. J Mol Biol (1998) 4.82

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins. J Mol Microbiol Biotechnol (1999) 4.64

Carbohydrate transport in bacteria. Microbiol Rev (1980) 4.56

A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria. J Bacteriol (1994) 4.14

Bacterial phosphoenolpyruvate: sugar phosphotransferase systems: structural, functional, and evolutionary interrelationships. Bacteriol Rev (1977) 4.13

Sugar transport. Properties of mutant bacteria defective in proteins of the phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem (1976) 3.57

Microbial genome analyses: comparative transport capabilities in eighteen prokaryotes. J Mol Biol (2000) 3.43

Protein phosphorylation and allosteric control of inducer exclusion and catabolite repression by the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Microbiol Rev (1989) 3.01

Analysis of a cis-active sequence mediating catabolite repression in gram-positive bacteria. Res Microbiol (1994) 3.00

Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis. J Bacteriol (1994) 2.86

A novel family of ubiquitous heavy metal ion transport proteins. J Membr Biol (1997) 2.76

Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Microbiology (1997) 2.73

Coordinate regulation of adenylate cyclase and carbohydrate permeases by the phosphoenolpyruvate:sugar phosphotransferase system in Salmonella typhimurium. J Biol Chem (1975) 2.64

The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Microbiology (2000) 2.64

Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analyses. Mol Microbiol (2001) 2.51

ATP-dependent protein kinase-catalyzed phosphorylation of a seryl residue in HPr, a phosphate carrier protein of the phosphotransferase system in Streptococcus pyogenes. Proc Natl Acad Sci U S A (1983) 2.43

The physiological behavior of enzyme I and heat-stable protein mutants of a bacterial phosphotransferase system. J Biol Chem (1970) 2.39

Sugar transport. 2nducer exclusion and regulation of the melibiose, maltose, glycerol, and lactose transport systems by the phosphoenolpyruvate:sugar phosphotransferase system. J Biol Chem (1976) 2.37

Regulation of methyl-beta-d-thiogalactopyranoside-6-phosphate accumulation in Streptococcus lactis by exclusion and expulsion mechanisms. J Bacteriol (1981) 2.36

Growth of Madin-Darby canine kidney epithelial cell (MDCK) line in hormone-supplemented, serum-free medium. Proc Natl Acad Sci U S A (1979) 2.34

The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs. Mol Microbiol (1996) 2.31

Mannitol-specific enzyme II of the bacterial phosphotransferase system. III. The nucleotide sequence of the permease gene. J Biol Chem (1983) 2.29

Sugar transport. The crr mutation: its effect on repression of enzyme synthesis. J Biol Chem (1976) 2.26

Permease-specific mutations in Salmonella typhimurium and Escherichia coli that release the glycerol, maltose, melibiose, and lactose transport systems from regulation by the phosphoenolpyruvate:sugar phosphotransferase system. J Bacteriol (1978) 2.20

The phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: properties, mechanism, and regulation. Crit Rev Microbiol (1988) 2.19

Novel proteins of the phosphotransferase system encoded within the rpoN operon of Escherichia coli. Enzyme IIANtr affects growth on organic nitrogen and the conditional lethality of an erats mutant. J Biol Chem (1995) 2.17

Transport proteins in bacteria: common themes in their design. Science (1992) 2.14

Sugar phosphate: sugar transphosphorylation and exchange group translocation catalyzed by the enzyme 11 complexes of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem (1977) 2.12

Properties of ATP-dependent protein kinase from Streptococcus pyogenes that phosphorylates a seryl residue in HPr, a phosphocarrier protein of the phosphotransferase system. J Bacteriol (1984) 2.11

Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria. Microbiology (1994) 2.09

Regulation of lactose permease activity by the phosphoenolpyruvate:sugar phosphotransferase system: evidence for direct binding of the glucose-specific enzyme III to the lactose permease. Proc Natl Acad Sci U S A (1982) 2.09

Mechanistic and physiological consequences of HPr(ser) phosphorylation on the activities of the phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: studies with site-specific mutants of HPr. EMBO J (1989) 2.08

Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process. Microbiol Rev (1989) 1.99

The drug/metabolite transporter superfamily. Eur J Biochem (2001) 1.99

Is the ribulose monophosphate pathway widely distributed in bacteria? Microbiology (1997) 1.99

Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae. FEBS Lett (1998) 1.98

A functional superfamily of sodium/solute symporters. Biochim Biophys Acta (1994) 1.97

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). J Cell Biol (1979) 1.96

The MIP family of integral membrane channel proteins: sequence comparisons, evolutionary relationships, reconstructed pathway of evolution, and proposed functional differentiation of the two repeated halves of the proteins. Crit Rev Biochem Mol Biol (1993) 1.93

The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli. Mol Microbiol (1995) 1.92

A novel protein kinase that controls carbon catabolite repression in bacteria. Mol Microbiol (1998) 1.89

A family of gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from gram-negative bacteria. FEMS Microbiol Lett (1997) 1.89

Horizontal transfer of a phosphatase gene as evidence for mosaic structure of the Salmonella genome. EMBO J (1992) 1.88

Phylogenetic characterization of the MIP family of transmembrane channel proteins. J Membr Biol (1996) 1.87

In vitro binding of the pleiotropic transcriptional regulatory protein, FruR, to the fru, pps, ace, pts and icd operons of Escherichia coli and Salmonella typhimurium. J Mol Biol (1993) 1.83

Evolution of the MIP family of integral membrane transport proteins. Mol Microbiol (1991) 1.83

Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins. J Membr Biol (1998) 1.83

Inducer exclusion and repression of enzyme synthesis in mutants of Salmonella typhimurium defective in enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem (1972) 1.82

Glucitol-specific enzymes of the phosphotransferase system in Escherichia coli. Nucleotide sequence of the gut operon. J Biol Chem (1987) 1.80

A novel family of channel-forming, autotransporting, bacterial virulence factors. Mol Membr Biol (1998) 1.79

Regulation of carbohydrate uptake and adenylate cyclase activity mediated by the enzymes II of the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli. J Biol Chem (1976) 1.79

Functional characterization of the Escherichia coli glycerol facilitator, GlpF, in Xenopus oocytes. J Biol Chem (1994) 1.76

Regulation of carbohydrate permeases and adenylate cyclase in Escherichia coli. Studies with mutant strains in which enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system is thermolabile. J Biol Chem (1976) 1.74

Functional interactions between proteins of the phosphoenolpyruvate:sugar phosphotransferase systems of Bacillus subtilis and Escherichia coli. J Biol Chem (1992) 1.73

Use of cloned mtl genes of Escherichia coli to introduce mtl deletion mutations into the chromosome. J Bacteriol (1983) 1.72

Mechanism of inducer expulsion in Streptococcus pyogenes: a two-step process activated by ATP. J Bacteriol (1983) 1.72

Fine control of adenylate cyclase by the phosphoenolpyruvate:sugar phosphotransferase systems in Escherichia coli and Salmonella typhimurium. J Bacteriol (1980) 1.71

Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions. Microbiology (2001) 1.69

Tight junction formation is closely linked to the polar redistribution of intramembranous particles in aggregating MDCK epithelia. Exp Cell Res (1979) 1.68

Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. J Mol Evol (1995) 1.67

Structure and evolution of a multidomain multiphosphoryl transfer protein. Nucleotide sequence of the fruB(HI) gene in Rhodobacter capsulatus and comparisons with homologous genes from other organisms. J Mol Biol (1990) 1.64

Allosteric regulation of glycerol kinase by enzyme IIIglc of the phosphotransferase system in Escherichia coli and Salmonella typhimurium. J Bacteriol (1985) 1.63

Salmonella virulence: new clues to intramacrophage survival. Trends Biochem Sci (1990) 1.62

A transport system for phosphoenolpyruvate, 2-phosphoglycerate, and 3-phosphoglycerate in Salmonella typhimurium. J Biol Chem (1975) 1.61

Phosphoenolpyruvate-dependent fructose phosphorylation in photosynthetic bacteria. J Biol Chem (1971) 1.61

Regulation of intracellular adenosine cyclic 3':5'-monophosphate levels in Escherichia coli and Salmonella typhimurium. Evidence for energy-dependent excretion of the cyclic nucleotide. J Biol Chem (1975) 1.61

Plasmid-directed synthesis of enzymes required for D-mannitol transport and utilization in Escherichia coli. Proc Natl Acad Sci U S A (1981) 1.60

A broad-specificity multidrug efflux pump requiring a pair of homologous SMR-type proteins. J Bacteriol (2000) 1.59

Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis. Microbiology (1999) 1.59

A new subfamily of bacterial ABC-type transport systems catalyzing export of drugs and carbohydrates. Protein Sci (1992) 1.56

Phylogenetic, structural and functional analyses of the LacI-GalR family of bacterial transcription factors. FEBS Lett (1995) 1.56

Enzyme I(Ntr) from Escherichia coli. A novel enzyme of the phosphoenolpyruvate-dependent phosphotransferase system exhibiting strict specificity for its phosphoryl acceptor, NPr. J Biol Chem (1999) 1.55

The complete phosphotransferase system in Escherichia coli. J Mol Microbiol Biotechnol (2001) 1.54

Purification of the mannitol-specific enzyme II of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system. J Biol Chem (1979) 1.53

Regulation of glycerol uptake by the phosphoenolpyruvate-sugar phosphotransferase system in Bacillus subtilis. J Bacteriol (1984) 1.49

Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution. Biochemistry (1989) 1.48

A common ancestor for bovine lens fiber major intrinsic protein, soybean nodulin-26 protein, and E. coli glycerol facilitator. Cell (1990) 1.46

Evidence for regulation of gluconeogenesis by the fructose phosphotransferase system in Salmonella typhimurium. J Bacteriol (1987) 1.46

The mitochondrial carrier family of transport proteins: structural, functional, and evolutionary relationships. Crit Rev Biochem Mol Biol (1993) 1.44

Identification of catalytic residues in the beta-glucoside permease of Escherichia coli by site-specific mutagenesis and demonstration of interdomain cross-reactivity between the beta-glucoside and glucose systems. J Biol Chem (1990) 1.43

The glucose permease of Bacillus subtilis is a single polypeptide chain that functions to energize the sucrose permease. J Biol Chem (1990) 1.43

Regulation of competence development and sugar utilization in Haemophilus influenzae Rd by a phosphoenolpyruvate:fructose phosphotransferase system. Mol Microbiol (1996) 1.43

The amino acid/auxin:proton symport permease family. Biochim Biophys Acta (1999) 1.43

A web-based program (WHAT) for the simultaneous prediction of hydropathy, amphipathicity, secondary structure and transmembrane topology for a single protein sequence. J Mol Microbiol Biotechnol (2001) 1.41

Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria. Protein Sci (1993) 1.40

Comparative genomics of microbial drug efflux systems. J Mol Microbiol Biotechnol (2001) 1.39

Altered transcriptional patterns affecting several metabolic pathways in strains of Salmonella typhimurium which overexpress the fructose regulon. J Bacteriol (1989) 1.39

Regulation of the maltose transport system of Escherichia coli by the glucose-specific enzyme III of the phosphoenolpyruvate-sugar phosphotransferase system. Characterization of inducer exclusion-resistant mutants and reconstitution of inducer exclusion in proteoliposomes. J Biol Chem (1990) 1.39

Involvement of lactose enzyme II of the phosphotransferase system in rapid expulsion of free galactosides from Streptococcus pyogenes. J Bacteriol (1983) 1.39

Cyclic AMP-dependent synthesis of fimbriae in Salmonella typhimurium: effects of cya and pts mutations. J Bacteriol (1978) 1.38

Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily. Yeast (1997) 1.36

A proposed link between nitrogen and carbon metabolism involving protein phosphorylation in bacteria. Protein Sci (1992) 1.36

Properties of a phosphoenolpyruvate: mannitol phosphotransferase system in Spirochaeta aurantia. J Biol Chem (1977) 1.35

A web-based program for the prediction of average hydropathy, average amphipathicity and average similarity of multiply aligned homologous proteins. J Mol Microbiol Biotechnol (2001) 1.35

TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology (1999) 1.32

New glycoprotein-associated amino acid transporters. J Membr Biol (1999) 1.32

Inhibition of the phosphoenolpyruvate:lactose phosphotransferase system and activation of a cytoplasmic sugar-phosphate phosphatase in Lactococcus lactis by ATP-dependent metabolite-activated phosphorylation of serine 46 in the phosphocarrier protein HPr. J Biol Chem (1994) 1.32