Published in J Biol Chem on June 05, 1993
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci U S A (1995) 2.93
Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. Proc Natl Acad Sci U S A (1994) 2.84
Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol (1997) 2.73
MutS mediates heteroduplex loop formation by a translocation mechanism. EMBO J (1997) 2.52
Human mismatch repair: reconstitution of a nick-directed bidirectional reaction. J Biol Chem (2005) 2.34
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev (2003) 2.28
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.25
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair. Proc Natl Acad Sci U S A (2001) 2.18
Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells. J Bacteriol (1996) 2.10
Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. J Biol Chem (2007) 2.09
Single-strand DNA-specific exonucleases in Escherichia coli. Roles in repair and mutation avoidance. Genetics (1998) 1.73
Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD. EMBO J (1998) 1.66
Surveying a supercoil domain by using the gamma delta resolution system in Salmonella typhimurium. J Bacteriol (1996) 1.58
Stabilization of diverged tandem repeats by mismatch repair: evidence for deletion formation via a misaligned replication intermediate. Proc Natl Acad Sci U S A (1996) 1.44
The crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activity. Proc Natl Acad Sci U S A (2002) 1.44
The UvrD helicase and its modulation by the mismatch repair protein MutL. Nucleic Acids Res (2006) 1.43
Alteration of gene conversion tract length and associated crossing over during plasmid gap repair in nuclease-deficient strains of Saccharomyces cerevisiae. Nucleic Acids Res (2000) 1.39
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair. Proc Natl Acad Sci U S A (2007) 1.38
Release of 5'-terminal deoxyribose-phosphate residues from incised abasic sites in DNA by the Escherichia coli RecJ protein. Nucleic Acids Res (1994) 1.35
The role of mismatch repair in the prevention of base pair mutations in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1998) 1.29
Mutational analysis of the RecJ exonuclease of Escherichia coli: identification of phosphoesterase motifs. J Bacteriol (1999) 1.26
Analysis of global gene expression and double-strand-break formation in DNA adenine methyltransferase- and mismatch repair-deficient Escherichia coli. J Bacteriol (2005) 1.09
Recognition of DNA alterations by the mismatch repair system. Biochem J (1999) 1.08
DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets. Br J Pharmacol (2009) 1.07
Requirement for Phe36 for DNA binding and mismatch repair by Escherichia coli MutS protein. Nucleic Acids Res (2000) 1.07
Mismatch Repair. J Biol Chem (2015) 1.06
Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes. PLoS Genet (2009) 1.05
Suppression of recJ exonuclease mutants of Escherichia coli by alterations in DNA helicases II (uvrD) and IV (helD). Genetics (1995) 1.02
Mismatch repair in Escherichia coli cells lacking single-strand exonucleases ExoI, ExoVII, and RecJ. J Bacteriol (1998) 0.98
Mutation avoidance and DNA repair proficiency in Ustilago maydis are differentially lost with progressive truncation of the REC1 gene product. Mol Cell Biol (1995) 0.98
Repair of heteroduplex DNA in Xenopus laevis oocytes. Genetics (1994) 0.97
Signal and noise in bridging PCR. BMC Biotechnol (2002) 0.96
Overexpression, purification and characterization of RecJ protein from Thermus thermophilus HB8 and its core domain. Nucleic Acids Res (2001) 0.96
Atomic force microscopy captures MutS tetramers initiating DNA mismatch repair. EMBO J (2011) 0.95
Role of RecJ-like protein with 5'-3' exonuclease activity in oligo(deoxy)nucleotide degradation. J Biol Chem (2010) 0.95
IF3-mediated suppression of a GUA initiation codon mutation in the recJ gene of Escherichia coli. J Bacteriol (1997) 0.93
Mismatch repair in Xenopus egg extracts: DNA strand breaks act as signals rather than excision points. Proc Natl Acad Sci U S A (1996) 0.93
DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding. Nucleic Acids Res (2013) 0.92
Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities. Mutat Res (2013) 0.91
Involvement of the beta clamp in methyl-directed mismatch repair in vitro. J Biol Chem (2009) 0.91
Yeast exonuclease 5 is essential for mitochondrial genome maintenance. Mol Cell Biol (2010) 0.88
Exonuclease 1-dependent and independent mismatch repair. DNA Repair (Amst) (2015) 0.88
Single-molecule multiparameter fluorescence spectroscopy reveals directional MutS binding to mismatched bases in DNA. Nucleic Acids Res (2012) 0.87
Mismatch repair in Schizosaccharomyces pombe requires the mutL homologous gene pms1: molecular cloning and functional analysis. Genetics (1997) 0.86
DNA mismatch repair efficiency and fidelity are elevated during DNA synthesis in human cells. Mutat Res (2008) 0.86
Base-flipping mechanism in postmismatch recognition by MutS. Biophys J (2011) 0.86
Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). Angew Chem Int Ed Engl (2016) 0.86
Exonuclease IX of Escherichia coli. Nucleic Acids Res (1998) 0.85
Involvement of mismatch repair in the reciprocal control of motility and adherence of uropathogenic Escherichia coli. Infect Immun (2012) 0.85
Identification of two conserved aspartic acid residues required for DNA digestion by a novel thermophilic Exonuclease VII in Thermotoga maritima. Nucleic Acids Res (2008) 0.84
Antagonism of ultraviolet-light mutagenesis by the methyl-directed mismatch-repair system of Escherichia coli. Genetics (2000) 0.83
Identification of two mismatch-binding activities in protein extracts of Schizosaccharomyces pombe. Nucleic Acids Res (1994) 0.82
Identification of RNase T as a high-copy suppressor of the UV sensitivity associated with single-strand DNA exonuclease deficiency in Escherichia coli. Genetics (1999) 0.82
DNA mismatch repair and Lynch syndrome. J Mol Histol (2006) 0.81
Short-patch correction of C/C mismatches in human cells. Nucleic Acids Res (2004) 0.81
Recognition and binding of mismatch repair proteins at an oncogenic hot spot. BMC Mol Biol (2005) 0.80
DNA Mismatch Repair Interacts with CAF-1- and ASF1A-H3-H4-dependent Histone (H3-H4)2 Tetramer Deposition. J Biol Chem (2016) 0.77
The DNA Exonucleases of Escherichia coli. Ecosal Plus (2011) 0.77
Mismatch repair at stop codons is directed independent of GATC methylation on the Escherichia coli chromosome. Sci Rep (2014) 0.77
Atomic force microscopy captures the initiation of methyl-directed DNA mismatch repair. DNA Repair (Amst) (2015) 0.77
Human DNA mismatch repair: coupling of mismatch recognition to strand-specific excision. Nucleic Acids Res (2007) 0.77
The fitness burden imposed by synthesising quorum sensing signals. Sci Rep (2016) 0.76
Modern aspects of the structural and functional organization of the DNA mismatch repair system. Acta Naturae (2013) 0.76
Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair. Nucleic Acids Res (2016) 0.75
A 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches. Nucleic Acids Res (2017) 0.75
Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell (1993) 6.61
Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease. J Biol Chem (1979) 5.75
Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli. Genetics (1983) 5.43
Methyl-directed repair of DNA base-pair mismatches in vitro. Proc Natl Acad Sci U S A (1983) 5.34
DNA mismatch correction. Annu Rev Biochem (1987) 5.33
DNA mismatch correction in a defined system. Science (1989) 4.98
Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proc Natl Acad Sci U S A (1986) 4.71
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science (1995) 4.48
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc Natl Acad Sci U S A (1990) 4.33
Mispair specificity of methyl-directed DNA mismatch correction in vitro. J Biol Chem (1988) 4.20
Enzymatic joining of polynucleotides. IX. A simple and rapid assay of polynucleotide joining (ligase) activity by measurement of circle formation from linear deoxyadenylate-deoxythymidylate copolymer. J Biol Chem (1970) 3.57
Mismatch repair deficiency in phenotypically normal human cells. Science (1995) 3.55
EcoRI endonuclease. Physical and catalytic properties of the homogenous enzyme. J Biol Chem (1976) 3.45
Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits. J Biol Chem (1975) 3.36
Genomic mismatch scanning: a new approach to genetic linkage mapping. Nat Genet (1993) 3.35
Isolation and characterization of the Escherichia coli mutL gene product. J Biol Chem (1989) 3.22
Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity. J Biol Chem (1975) 3.18
Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase. J Mol Biol (1973) 3.12
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci U S A (1993) 3.07
Deoxyribonucleic acid ligase. Isolation and physical characterization of the homogeneous enzyme from Escherichia coli. J Biol Chem (1973) 3.04
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae. Genetics (1995) 3.02
Repair of DNA base-pair mismatches in extracts of Escherichia coli. Cold Spring Harb Symp Quant Biol (1984) 2.96
Isolation and characterization of the Escherichia coli mutH gene product. J Biol Chem (1987) 2.94
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci U S A (1995) 2.93
Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. Proc Natl Acad Sci U S A (1989) 2.87
Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. Proc Natl Acad Sci U S A (1994) 2.84
Initiation of methyl-directed mismatch repair. J Biol Chem (1992) 2.82
T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits. J Biol Chem (1979) 2.76
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. J Biol Chem (1998) 2.67
DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes. J Biol Chem (1981) 2.63
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci U S A (1996) 2.57
MutS mediates heteroduplex loop formation by a translocation mechanism. EMBO J (1997) 2.52
Structures and mechanisms of DNA restriction and modification enzymes. Q Rev Biophys (1979) 2.51
Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme. J Biol Chem (1982) 2.45
Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. J Biol Chem (1993) 2.38
EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme. J Biol Chem (1977) 2.32
Involvement of outside DNA sequences in the major kinetic path by which EcoRI endonuclease locates and leaves its recognition sequence. Proc Natl Acad Sci U S A (1982) 2.29
Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction. Proc Natl Acad Sci U S A (1988) 2.29
Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol (1981) 2.21
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair. Proc Natl Acad Sci U S A (2001) 2.18
Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. J Biol Chem (1996) 2.01
Studies on sequence recognition by type II restriction and modification enzymes. CRC Crit Rev Biochem (1982) 2.01
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase. J Biol Chem (1993) 1.98
Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction. Proc Natl Acad Sci U S A (1987) 1.90
Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1998) 1.90
Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific interactions in EcoRI catalysis. J Biol Chem (1985) 1.87
Inhibition of FEN-1 processing by DNA secondary structure at trinucleotide repeats. Mol Cell (1999) 1.83
Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol Cell Biol (1997) 1.79
Thermodynamic parameters governing interaction of EcoRI endonuclease with specific and nonspecific DNA sequences. J Biol Chem (1983) 1.76
Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair. J Biol Chem (2001) 1.75
Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism. J Biol Chem (1998) 1.66
The negative charge of Glu-111 is required to activate the cleavage center of EcoRI endonuclease. J Biol Chem (1989) 1.65
DNA determinants important in sequence recognition by Eco RI endonuclease. J Biol Chem (1981) 1.64
hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage. Proc Natl Acad Sci U S A (1999) 1.63
The DNA sequences encoding plsB and dgk loci of Escherichia coli. J Biol Chem (1983) 1.62
MutS and MutL activate DNA helicase II in a mismatch-dependent manner. J Biol Chem (1998) 1.62
DNA polymerase delta is required for human mismatch repair in vitro. J Biol Chem (1997) 1.61
Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family. Gene (1987) 1.60
Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex. J Biol Chem (1998) 1.59
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. Proc Natl Acad Sci U S A (1997) 1.58
Bidirectional excision in methyl-directed mismatch repair. J Biol Chem (1993) 1.57
Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Mol Cell Biol (1997) 1.53
Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-encoded protein. Nucleic Acids Res (1988) 1.48
Mechanisms of DNA-mismatch correction. Mutat Res (1990) 1.44
The kinetic mechanism of EcoRI endonuclease. J Biol Chem (1999) 1.43
Positive-selection cloning vehicle useful for overproduction of hybrid proteins. J Bacteriol (1983) 1.42
The MutL ATPase is required for mismatch repair. J Biol Chem (2000) 1.40
Modulation of MutS ATP hydrolysis by DNA cofactors. Biochemistry (2000) 1.37
DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes. J Biol Chem (2001) 1.37
MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2. Curr Biol (1996) 1.35
Removal of polymerase-produced mutant sequences from PCR products. Proc Natl Acad Sci U S A (1997) 1.34
Instability of CAG and CTG trinucleotide repeats in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.32
Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis. J Biol Chem (2001) 1.31
Substrate dependence of the mechanism of EcoRI endonuclease. Nucleic Acids Res (1978) 1.28
Glu-111 is required for activation of the DNA cleavage center of EcoRI endonuclease. J Biol Chem (1989) 1.27
Isolation of gram quantities of EcoRI restriction and modification enzymes from an overproducing strain. J Biol Chem (1984) 1.26
Enzymatic joining of polynucleotides. XI. Reversal of Escherichia coli deoxyribonucleic acid ligase reaction. J Biol Chem (1972) 1.24
Methylator resistance mediated by mismatch repair deficiency in a glioblastoma multiforme xenograft. Cancer Res (1997) 1.24
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase. J Biol Chem (1994) 1.20
Enzymatic characterization of a mutant of Escherichia coli with an altered DNA ligase. Proc Natl Acad Sci U S A (1971) 1.19
Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. J Biol Chem (1980) 1.18
DNA-dependent activation of the hMutSalpha ATPase. J Biol Chem (1998) 1.17
Stabilizing effects of interruptions on trinucleotide repeat expansions in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.16
Role of the 2-amino group of deoxyguanosine in sequence recognition by EcoRI restriction and modification enzymes. J Biol Chem (1977) 1.14
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Mol Cell Biol (1998) 1.11
Regulation of phospholipid biosynthesis in Escherichia coli. Cloning of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J Biol Chem (1980) 1.10
Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability. Oncogene (1996) 1.09
Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae. Genetics (2001) 1.09
Differential effects of the mismatch repair genes MSH2 and MSH3 on homeologous recombination in Saccharomyces cerevisiae. Mol Gen Genet (1997) 1.08
Characterization of a DNA mismatch-binding activity in yeast extracts. J Biol Chem (1993) 1.08
A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC). Proc Natl Acad Sci U S A (1995) 1.07
T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. J Biol Chem (1983) 1.06
Membrane phospholipid synthesis in Escherichia coli. Identification of the sn-glycerol-3-phosphate acyltransferase polypeptide as the plsB gene product. J Biol Chem (1980) 1.06
Mutation detection with MutH, MutL, and MutS mismatch repair proteins. Proc Natl Acad Sci U S A (1996) 1.00
Gap formation is associated with methyl-directed mismatch correction under conditions of restricted DNA synthesis. Genome (1989) 0.99
Direct atomic force microscope imaging of EcoRI endonuclease site specifically bound to plasmid DNA molecules. Proc Natl Acad Sci U S A (1996) 0.98
The DNA helicase activities of Rad3 protein of Saccharomyces cerevisiae and helicase II of Escherichia coli are differentially inhibited by covalent and noncovalent DNA modifications. J Biol Chem (1993) 0.98
Methyl-directed DNA mismatch repair in Escherichia coli. Mutat Res (1988) 0.95