GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

PubWeight™: 6.73‹?› | Rank: Top 1%

🔗 View Article (PMID 8493557)

Published in Science on May 21, 1993

Authors

L F Lin1, D H Doherty, J D Lile, S Bektesh, F Collins

Author Affiliations

1: Synergen, Inc., Boulder, CO 80301.

Articles citing this

(truncated to the top 100)

Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A (2004) 4.77

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci U S A (1997) 4.20

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A (1998) 2.76

Neurobiology of the incubation of drug craving. Trends Neurosci (2011) 2.65

GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron (1998) 2.34

Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology (2010) 2.31

Cloning and characterization of a human type II receptor for bone morphogenetic proteins. Proc Natl Acad Sci U S A (1995) 2.19

Peripheral nerve regeneration and neurotrophic factors. J Anat (1999) 1.96

The germline stem cell niche unit in mammalian testes. Physiol Rev (2012) 1.86

A femtomolar-acting neuroprotective peptide. J Clin Invest (1996) 1.85

Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1. J Virol (1993) 1.78

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol (1995) 1.73

Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. Am J Hum Genet (2004) 1.70

Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis. J Med Genet (2000) 1.61

Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation. Stem Cells (2007) 1.61

Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc Natl Acad Sci U S A (1996) 1.58

Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Mol Ther (2009) 1.52

Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease. Proc Natl Acad Sci U S A (2006) 1.51

Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biol Psychiatry (2009) 1.48

GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function. PLoS Genet (2015) 1.45

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke (2010) 1.44

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases. Biochem J (1996) 1.41

Yangjing Capsule Extract Promotes Proliferation of GC-1 Spg Cells. Evid Based Complement Alternat Med (2014) 1.41

Long distance directional growth of dopaminergic axons along pathways of netrin-1 and GDNF. Exp Neurol (2013) 1.40

Excessive alcohol consumption is blocked by glial cell line-derived neurotrophic factor. Alcohol (2009) 1.39

Molecular evolution of a developmental pathway: phylogenetic analyses of transforming growth factor-beta family ligands, receptors and Smad signal transducers. Genetics (1999) 1.39

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. Int J Neuropsychopharmacol (2008) 1.38

Protection of visual functions by human neural progenitors in a rat model of retinal disease. PLoS One (2007) 1.38

Assessment of stromal-derived inducing activity in the generation of dopaminergic neurons from human embryonic stem cells. Stem Cells (2008) 1.37

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci (2006) 1.36

Gfra1 silencing in mouse spermatogonial stem cells results in their differentiation via the inactivation of RET tyrosine kinase. Biol Reprod (2007) 1.36

Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves. J Natl Cancer Inst (2010) 1.36

Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia. Prog Neurobiol (2010) 1.36

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc Natl Acad Sci U S A (2008) 1.35

Treatment of Parkinson's disease with trophic factors. Neurotherapeutics (2008) 1.35

Pharmacokinetics and safety in rhesus monkeys of a monoclonal antibody-GDNF fusion protein for targeted blood-brain barrier delivery. Pharm Res (2009) 1.32

Gdnf signaling pathways within the mammalian spermatogonial stem cell niche. Mol Cell Endocrinol (2008) 1.32

Role of BDNF and GDNF in drug reward and relapse: a review. Neurosci Biobehav Rev (2009) 1.31

Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 1.31

Evaluation of copy number variations reveals novel candidate genes in autism spectrum disorder-associated pathways. Hum Mol Genet (2012) 1.29

Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol (1997) 1.28

Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat. J Neurosci Res (2006) 1.27

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc Natl Acad Sci U S A (1997) 1.26

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci U S A (1995) 1.26

GDNF-enhanced axonal regeneration and myelination following spinal cord injury is mediated by primary effects on neurons. Glia (2009) 1.26

GDNF is not required for catecholaminergic neuron survival in vivo. Nat Neurosci (2015) 1.25

AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth. Mol Ther (2011) 1.25

Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc Natl Acad Sci U S A (1995) 1.24

Intermittent ethanol access schedule in rats as a preclinical model of alcohol abuse. Alcohol (2014) 1.24

Progress in neuroprotective strategies for preventing epilepsy. Prog Neurobiol (2007) 1.24

TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity. EMBO J (1995) 1.23

GDNF hyperalgesia is mediated by PLCgamma, MAPK/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican. Eur J Neurosci (2008) 1.23

Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts? Cell Div (2007) 1.22

The neurotrophic factor artemin promotes pancreatic cancer invasion. Ann Surg (2006) 1.22

Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa. Neuropsychopharmacology (2011) 1.21

Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci (2010) 1.20

Signaling pathways mediating alcohol effects. Curr Top Behav Neurosci (2013) 1.20

The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding. J Biol Chem (2008) 1.19

Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin. J Cell Biol (2011) 1.18

Astrocytes and therapeutics for Parkinson's disease. Neurotherapeutics (2010) 1.18

Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proc Natl Acad Sci U S A (1997) 1.17

Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. J Neurosci (2011) 1.17

Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease. Brain Res (2005) 1.15

An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy. PLoS One (2014) 1.15

Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. J Neurosci (2010) 1.14

Regional, developmental, and cell cycle-dependent differences in mu, delta, and kappa-opioid receptor expression among cultured mouse astrocytes. Glia (1998) 1.14

Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron (2000) 1.14

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle. Front Aging Neurosci (2014) 1.14

Functional RET G691S polymorphism in cutaneous malignant melanoma. Oncogene (2009) 1.14

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc Natl Acad Sci U S A (1997) 1.14

Parkinson's disease: gene therapies. Cold Spring Harb Perspect Med (2012) 1.13

Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev (2003) 1.13

Mitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells: evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade. J Neurochem (2000) 1.12

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiol Dis (2009) 1.12

Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand? Front Neurosci (2010) 1.12

A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells. PLoS One (2009) 1.11

RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc Natl Acad Sci U S A (2007) 1.11

An in vivo characterization of trophic factor production following neural precursor cell or bone marrow stromal cell transplantation for spinal cord injury. Stem Cells Dev (2012) 1.11

Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease. Hum Gene Ther (2004) 1.10

Hibernation-like state induced by an opioid peptide protects against experimental stroke. BMC Biol (2009) 1.09

Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders. Am J Neurodegener Dis (2013) 1.08

Targets for neuroprotection in Parkinson's disease. Biochim Biophys Acta (2008) 1.08

Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease. PLoS One (2009) 1.07

Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice. J Neurosci (2007) 1.07

Gene therapy in the inner ear using adenovirus vectors. Adv Otorhinolaryngol (2009) 1.07

Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. Neuropsychopharmacology (2009) 1.07

GDNF--a potential target to treat addiction. Pharmacol Ther (2008) 1.07

Pleiotrophin is a neurotrophic factor for spinal motor neurons. Proc Natl Acad Sci U S A (2007) 1.06

Defining and designing polymers and hydrogels for neural tissue engineering. Neurosci Res (2011) 1.06

Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit. Neuron (2012) 1.05

GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family. Proc Natl Acad Sci U S A (1998) 1.04

GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells. Mol Cell Biol (2006) 1.04

Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proc Natl Acad Sci U S A (1995) 1.03

Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration. Mol Vis (2009) 1.03

TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors. Am J Physiol Lung Cell Mol Physiol (2012) 1.02

GDNF is an endogenous negative regulator of ethanol-mediated reward and of ethanol consumption after a period of abstinence. Alcohol Clin Exp Res (2009) 1.02

Molecular determinants of the face map development in the trigeminal brainstem. Anat Rec A Discov Mol Cell Evol Biol (2006) 1.02

Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PLoS One (2012) 1.02

Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum. PLoS One (2009) 1.02

Trophic factors therapy in Parkinson's disease. Prog Brain Res (2009) 1.02

Articles cited by this

Promising protein for Parkinson's. Science (1993) 6.51

Articles by these authors

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Effects of the obese gene product on body weight regulation in ob/ob mice. Science (1995) 13.57

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science (1999) 13.19

Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell (1996) 10.40

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell (1990) 4.12

Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99

Expectations and high school change: teacher-researcher collaboration to prevent school failure. Am J Community Psychol (1991) 3.62

Mechanism of NO-induced oxidation of myoglobin and hemoglobin. Biochemistry (1996) 3.36

Determination of the amount of homology required for recombination in bacteriophage T4. Cell (1982) 3.35

Evidence for a prostate cancer susceptibility locus on the X chromosome. Nat Genet (1998) 2.90

Analysis of the native quaternary structure of vanilloid receptor 1. J Biol Chem (2001) 2.55

Functional recovery in parkinsonian monkeys treated with GDNF. Nature (1996) 2.35

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours. Nat Genet (2000) 2.26

Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs. J Infect Dis (1998) 2.07

A medium-density genetic linkage map of the bovine genome. Mamm Genome (1997) 1.85

Recruitment experience in the first phase of the African American Hereditary Prostate Cancer (AAHPC) study. Ann Epidemiol (2000) 1.79

Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences. Infect Immun (1999) 1.63

Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections. Eur J Clin Microbiol (1985) 1.59

Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor. Science (1991) 1.58

Genetic information and the workplace: legislative approaches and policy changes. Science (1997) 1.56

Induction of neurite outgrowth by a conditioned-medium factor bound to the culture substratum. Proc Natl Acad Sci U S A (1978) 1.52

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). Science (1989) 1.50

In search of susceptibility genes for type 2 diabetes in West Africa: the design and results of the first phase of the AADM study. Ann Epidemiol (2001) 1.49

Genetic engineering of polysaccharide structure: production of variants of xanthan gum in Xanthomonas campestris. Biotechnol Prog (1990) 1.42

Axon initiation by ciliary neurons in culture. Dev Biol (1978) 1.38

Marfan syndrome: no evidence for heterogeneity in different populations, and more precise mapping of the gene. Am J Hum Genet (1991) 1.35

Sequences of human repetitive DNA, non-alpha-globin genes, and major histocompatibility locus genes. Cold Spring Harb Symp Quant Biol (1983) 1.33

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res Bull (1995) 1.29

Surveillance of insecticide resistance in head lice using biochemical and molecular methods. Arch Dis Child (2006) 1.29

A comparison of isozymes of five axenic Giardia isolates. J Parasitol (1983) 1.24

Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp Neurol (1993) 1.19

CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium bovis BCG vaccination in mice challenged with M. tuberculosis. Infect Immun (2000) 1.19

Multiple congenital defects associated with maternal use of topical tretinoin. Lancet (1993) 1.18

The immunogenicity of single and combination DNA vaccines against tuberculosis. Vaccine (2000) 1.17

Invasive meningococcal disease in Canada, 1 January 1997 to 31 December 1998. Can Commun Dis Rep (2000) 1.17

Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron (2000) 1.14

A reevaluation of the fertilizin hypothesis of sperm agglutination and the description of a novel form of sperm adhesion. Dev Biol (1976) 1.13

Bacterial and phage mutations that reveal helix-unwinding activities required for bacteriophage T4 DNA replication. Proc Natl Acad Sci U S A (1983) 1.13

The role of alternative mRNA splicing in generating heterogeneity within the Anopheles gambiae class I glutathione S-transferase family. Proc Natl Acad Sci U S A (1998) 1.12

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia. Blood (1994) 1.12

Neurite outgrowth induced by the substrate associated material from nonneuronal cells. Dev Biol (1980) 1.11

The distinction between multiple retinal pigment epithelial hamartomata (MRPEH) in familial adenomatous polyposis (FAP) and congenital hypertrophy of the retinal pigment epithelium (CHRPE) Aust N Z J Ophthalmol (1993) 1.09

Differential phylogenetic footprinting as a means to identify base changes responsible for recruitment of the anthropoid gamma gene to a fetal expression pattern. J Biol Chem (1994) 1.05

The role of calcium ions in the acrosome reaction of sea urchin sperm: regulation of exocytosis. Exp Cell Res (1977) 1.05

The in vitro induction of human immunodeficiency virus (HIV) replication in purified protein derivative-positive HIV-infected persons by recall antigen response to Mycobacterium tuberculosis is the result of a balance of the effects of endogenous interleukin-2 and proinflammatory and antiinflammatory cytokines. J Infect Dis (1998) 1.02

Optimization of heterologous protein production in Escherichia coli. Curr Opin Biotechnol (1996) 1.02

A genome-wide scan for quantitative trait loci linked to obesity phenotypes among West Africans. Int J Obes (Lond) (2005) 0.95

In vitro Evidence for two distinct hippocampal growth factors: basis of neuronal plasticity? Science (1982) 0.94

Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor. J Neurochem (1994) 0.94

Clinical characteristics of African-American men with hereditary prostate cancer: the AAHPC Study. Prostate Cancer Prostatic Dis (2004) 0.94

Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience (1994) 0.93

Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys. J Pharmacol Exp Ther (1997) 0.93

A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma. Genes Chromosomes Cancer (1990) 0.91

Glial cell line-derived neurotrophic factor: distribution and pharmacology in the rat following a bolus intraventricular injection. Brain Res (1997) 0.91

Genetic studies on capsid-length determination in bacteriophage T4. I. Isolation and partial characterization of second-site revertants of a gene 23 mutation affecting capsid length. J Virol (1982) 0.91

Glial cell line-derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6-hydroxydopamine-lesioned adult rats: comparison of intraventricular and intranigral delivery. Neuroscience (1997) 0.89

Elongating nerve fibers are guided by a pathway of material released from embryonic nonneuronal cells. Proc Natl Acad Sci U S A (1980) 0.89

National working conference on smoking and body weight. Task Force 1: Mechanisms relevant to the relations between cigarette smoking and body weight. Health Psychol (1992) 0.88

Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats. Brain Res Mol Brain Res (1994) 0.88

Genetic studies on capsid-length determination in bacteriophage T4. II. Genetic evidence that specific protein-protein interactions are involved. J Virol (1982) 0.88

Morphological and functional effects of intranigrally administered GDNF in normal rhesus monkeys. J Comp Neurol (1995) 0.87

Human leptin characterization. Nature (1996) 0.86

Non-random x-inactivation in the female mule. Nature (1969) 0.86

On the role of the single-stranded DNA binding protein of bacteriophage T4 in DNA metabolism. I. Isolation and genetic characterization of new mutations in gene 32 of bacteriophage T4. Mol Gen Genet (1982) 0.86

The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival. Brain Res (1989) 0.85

Maturation of the major ubiquitin gene transcript in Caenorhabditis elegans involves the acquisition of a trans-spliced leader. J Biol Chem (1988) 0.85

DXS165 detects a translocation breakpoint in a woman with choroideremia and a de novo X; 13 translocation. Genomics (1990) 0.85

A class I jumping clone places the HLA-G gene approximately 100 kilobases from HLA-H within the HLA-A subregion of the human MHC. Genomics (1991) 0.84

An additive interaction between the NFkappaB and estrogen receptor signalling pathways in human endometrial epithelial cells. Hum Reprod (2009) 0.84

Reversible developmental change in the ability of ciliary ganglion neurons to extend neurites in culture. J Neurosci (1982) 0.84

GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged parkinsonian mice. Neuroreport (1998) 0.84

Cognitive and non-cognitive characteristics of minority medical school applicants. J Natl Med Assoc (1975) 0.84

Nitric oxide synthase is expressed in experimental malignant glioma and influences tumour blood flow. Acta Neurochir (Wien) (1996) 0.83

Biology of glial cell line-derived neurotrophic factor (GDNF): implications for the use of GDNF to treat Parkinson's disease. Neurodegeneration (1996) 0.83

Localisation of the endpoints of deletions in the 5' region of the Duchenne gene using a sequence isolated by chromosome jumping. Nucleic Acids Res (1988) 0.83

Expression and characterization of recombinant human ciliary neurotrophic factor from Escherichia coli. Biochim Biophys Acta (1991) 0.83

African-American heredity prostate cancer study: a model for genetic research. J Natl Med Assoc (2001) 0.83

Malignant melanotic schwannoma of the bronchus. J Clin Pathol (1987) 0.83

A self-management concept for men at the community level: the 'Waist' Disposal Challenge. J Health Psychol (2009) 0.82

General population screening for cystic fibrosis is premature. Am J Hum Genet (1992) 0.82

Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys. Ann Neurol (1997) 0.82

Conditioned medium increases the rate of neurite elongation: separation of this activity from the substratum-bound inducer of neurite outgrowth. J Neurosci (1982) 0.82

Electrophoretic similarity of the ciliary ganglion survival factors from different tissues and species. Dev Biol (1985) 0.82

An amino acid substitution in the pyruvate dehydrogenase E1 alpha gene, affecting mitochondrial import of the precursor protein. Am J Hum Genet (1995) 0.82

Intellectual and attitudinal characteristics of medical students selecting family practice. J Fam Pract (1975) 0.81

Broadening the phenotype of LRP2 mutations: a new mutation in LRP2 causes a predominantly ocular phenotype suggestive of Stickler syndrome. Clin Genet (2013) 0.81

Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease. J Med Chem (2000) 0.81

An effect of nerve growth factor on parasympathetic neurite outgrowth. Proc Natl Acad Sci U S A (1983) 0.81

Oral-facial-digital syndrome and retinal abnormalities with autosomal recessive inheritance. Am J Med Genet (1993) 0.81

Structure of and alterations to defective murine sarcoma virus particles lacking envelope proteins and core polyprotein cleavage. J Virol (1980) 0.81

The spatial control of ganglionic neurite growth by the substrate-associated material from conditioned medium: an experimental model of haptotaxis. J Neurosci (1984) 0.80

Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors. Proc Natl Acad Sci U S A (1996) 0.80

Characterization of two distinct monoclonal antibodies specific for glial cell line-derived neurotrophic factor. J Neurochem (1998) 0.80

N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras. J Biol Chem (1996) 0.80

Isolation and characterization of ciliary neurotrophic factor from rabbit sciatic nerves. J Biol Chem (1990) 0.80

Glial cell line-derived neurotrophic factor. Potential for otoprotection. Ann N Y Acad Sci (1999) 0.79

An effect of nerve growth factor on the parasympathetic ciliary ganglion. J Neurosci (1984) 0.79