Published in Carcinogenesis on May 01, 1993
Initiation of DNA interstrand cross-link repair in humans: the nucleotide excision repair system makes dual incisions 5' to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand. Mol Cell Biol (1997) 1.58
Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells. Nucleic Acids Res (2000) 0.89
Fanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity. Environ Health Perspect (2002) 0.83
FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: activation is not required for repair of Cr(VI)-induced DSBs. Mutat Res (2006) 0.81
Rearrangement of interstrand cross-links into intrastrand cross-links in cis-diamminedichloroplatinum(II)-modified DNA. Nucleic Acids Res (1997) 0.79
The use of alpha-DNA as an internal standard in the detection and quantitation of DNA damage in specific genes using Southern blotting. Nucleic Acids Res (1996) 0.75
DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell (1985) 7.62
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res (2001) 4.47
Preferential DNA repair of an active gene in human cells. Proc Natl Acad Sci U S A (1986) 3.42
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity. J Biol Chem (2000) 3.17
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep (2000) 2.88
Functional and physical interaction between WRN helicase and human replication protein A. J Biol Chem (1999) 2.77
p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat Genet (1995) 2.47
Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene. Proc Natl Acad Sci U S A (1986) 2.29
Ku complex interacts with and stimulates the Werner protein. Genes Dev (2000) 2.21
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO J (2001) 2.21
Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos. Cell (1986) 2.13
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer Res (2001) 2.04
Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem (1997) 2.02
Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J Exp Med (1998) 2.00
Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells. Carcinogenesis (1992) 1.92
Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO. Nucleic Acids Res (1999) 1.90
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Natl Acad Sci U S A (1998) 1.86
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc Natl Acad Sci U S A (1997) 1.74
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair. J Biol Chem (2000) 1.66
Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair. J Biol Chem (1999) 1.65
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair. Biochemistry (2001) 1.56
DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci U S A (1995) 1.56
Mitochondrial DNA repair pathways. Mutat Res (1999) 1.53
Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts. J Biol Chem (1998) 1.52
Characterization of a DNA repair domain containing the dihydrofolate reductase gene in Chinese hamster ovary cells. J Biol Chem (1986) 1.51
Deficient DNA repair capacity, a predisposing factor in breast cancer. Br J Cancer (1996) 1.46
ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients. J Natl Cancer Inst (1992) 1.46
Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants. Heart Rhythm (2012) 1.43
Acute leukemia following cisplatin-based chemotherapy in a patient with ovarian cancer. J Natl Cancer Inst (1990) 1.41
DNA repair, mitochondria, and neurodegeneration. Neuroscience (2006) 1.41
Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines. Mol Cell Biol (1992) 1.39
Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer Res (2001) 1.38
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA. J Biol Chem (2001) 1.37
Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA. EMBO J (2001) 1.37
An oxidative damage-specific endonuclease from rat liver mitochondria. J Biol Chem (1997) 1.36
Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin. J Biol Chem (1991) 1.32
Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein. J Biol Chem (2001) 1.32
Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells. J Biol Chem (1991) 1.32
Alternative splicing of human inducible nitric-oxide synthase mRNA. tissue-specific regulation and induction by cytokines. J Biol Chem (1996) 1.31
Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis. Mol Biol Cell (1997) 1.31
Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes. Immunology (2001) 1.30
Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. Nucleic Acids Res (1999) 1.30
The Werner syndrome protein is involved in RNA polymerase II transcription. Mol Biol Cell (1999) 1.29
A comparison of the British number plate and Snellen vision tests for car drivers. Ophthalmic Physiol Opt (1981) 1.29
Age-associated change in mitochondrial DNA damage. Free Radic Res (1998) 1.28
Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein. Nucleic Acids Res (1997) 1.28
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res (2000) 1.26
Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases. J Biol Chem (2000) 1.25
Genome-wide meta-analyses of smoking behaviors in African Americans. Transl Psychiatry (2012) 1.23
A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism. Carcinogenesis (2000) 1.21
Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria. Nucleic Acids Res (1999) 1.21
Aberrant expression of MUC5AC and MUC6 gastric mucin genes in colorectal polyps. Int J Cancer (1999) 1.20
Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands. Biochemistry (2001) 1.20
The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity. Nucleic Acids Res (2004) 1.19
Base excision repair in nuclear and mitochondrial DNA. Prog Nucleic Acid Res Mol Biol (2001) 1.18
Immunoglobulin A subclasses in infants' saliva and in saliva and milk from their mothers. J Pediatr (1994) 1.18
Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells. J Biol Chem (1989) 1.18
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA. Nucleic Acids Res (2000) 1.17
Cloning and characterization of human inducible nitric oxide synthase splice variants: a domain, encoded by exons 8 and 9, is critical for dimerization. Proc Natl Acad Sci U S A (1998) 1.15
Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells. Nucleic Acids Res (1997) 1.15
Quantification of aminofluorene adduct formation and repair in defined DNA sequences in mammalian cells using the UVRABC nuclease. J Biol Chem (1989) 1.14
DNA base excision repair in human malaria parasites is predominantly by a long-patch pathway. Biochemistry (2000) 1.14
Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction. Nucleic Acids Res (2005) 1.13
General method for quantifying base adducts in specific mammalian genes. Proc Natl Acad Sci U S A (1988) 1.13
Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis. Free Radic Biol Med (2009) 1.12
A UV-responsive G2 checkpoint in rodent cells. Mol Cell Biol (1995) 1.11
The C-terminal domain of p21 inhibits nucleotide excision repair In vitro and In vivo. Mol Biol Cell (1999) 1.08
Genomic heterogeneity of nucleotide excision repair. Gene (2000) 1.08
p53 Modulates the exonuclease activity of Werner syndrome protein. J Biol Chem (2001) 1.07
Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk. Hum Exp Toxicol (2012) 1.07
Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts. Nucleic Acids Res (1999) 1.06
Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells. J Biol Chem (1990) 1.06
No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free Radic Biol Med (2005) 1.06
DNA repair in the metallothionein gene increases with transcriptional activation. Nucleic Acids Res (1987) 1.06
Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis. Oncogene (2000) 1.06
Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide. Cancer Res (1992) 1.05
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA. Nucleic Acids Res (2001) 1.05
Mitochondrial endogenous oxidative damage has been overestimated. FASEB J (2000) 1.05
Repair of individual DNA strands in the hamster dihydrofolate reductase gene after treatment with ultraviolet light, alkylating agents, and cisplatin. J Biol Chem (1993) 1.04
Single nucleotide patch base excision repair is the major pathway for removal of thymine glycol from DNA in human cell extracts. J Biol Chem (2000) 1.03
Accelerated methylation of ribosomal RNA genes during the cellular senescence of Werner syndrome fibroblasts. FASEB J (2000) 1.02
Inhibition of RNA polymerase II transcription in human cell extracts by cisplatin DNA damage. Biochemistry (1999) 1.02
DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts. Free Radic Biol Med (2001) 1.02
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair. Mol Biol Cell (1999) 1.00
Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage. Nucleic Acids Res (1994) 0.99
Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features. J Biol Chem (1993) 0.99
Gene-specific DNA repair of UV-induced cyclobutane pyrimidine dimers in some cancer-prone and premature-aging human syndromes. Mutat Res (1994) 0.99
Gene-specific nuclear and mitochondrial repair of formamidopyrimidine DNA glycosylase-sensitive sites in Chinese hamster ovary cells. Mutat Res (1996) 0.99
Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cells. Mol Cell Biol (1989) 0.99
Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle. Mol Cell Biol (1995) 0.98
Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction. FASEB J (2004) 0.98
DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA. Nucleic Acids Res (2004) 0.97
DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice. Mol Cell Biol (1991) 0.96
DNA repair and its pathogenetic implications. Lab Invest (1989) 0.96
Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells. Nucleic Acids Res (1999) 0.96
Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA. Nucleic Acids Res (1998) 0.96
Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain. J Mol Biol (1999) 0.95
Telomere reduction and telomerase inactivation during neuronal cell differentiation. Biochem Biophys Res Commun (1996) 0.95
Relationship between DNA cross-links, cell cycle, and apoptosis in Burkitt's lymphoma cell lines differing in sensitivity to nitrogen mustard. Cancer Res (1991) 0.95