Published in Nucleic Acids Res on December 10, 1987
Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes. Mol Cell Biol (1991) 2.53
Strand-specificity in the transformation of yeast with synthetic oligonucleotides. Genetics (1992) 1.59
Differential repair of DNA damage in the human metallothionein gene family. Mol Cell Biol (1988) 1.25
General method for quantifying base adducts in specific mammalian genes. Proc Natl Acad Sci U S A (1988) 1.13
Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts. Proc Natl Acad Sci U S A (1992) 1.10
Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cells. Mol Cell Biol (1989) 0.99
DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice. Mol Cell Biol (1991) 0.96
Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA. Nucleic Acids Res (1998) 0.96
DNA repair defects associated with chromosomal translocation breaksite regions. Mol Cell Biol (1994) 0.86
Preferential repair of UV damage in highly transcribed DNA diminishes UV-induced intrachromosomal recombination in mammalian cells. Mol Cell Biol (1994) 0.81
Metallothionein. Annu Rev Biochem (1986) 8.12
DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell (1985) 7.62
Preferential DNA repair of an active gene in human cells. Proc Natl Acad Sci U S A (1986) 3.42
Transcriptionally active chromatin. Biochim Biophys Acta (1984) 2.39
Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene. Proc Natl Acad Sci U S A (1986) 2.29
Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos. Cell (1986) 2.13
cDNA cloning and nucleotide sequence comparison of Chinese hamster metallothionein I and II mRNAs. Nucleic Acids Res (1983) 1.70
Characterization of a DNA repair domain containing the dihydrofolate reductase gene in Chinese hamster ovary cells. J Biol Chem (1986) 1.51
Preferential repair of nuclear matrix associated DNA in xeroderma pigmentosum complementation group C. Mutat Res (1984) 1.31
Coordinate amplification of metallothionein I and II genes in cadmium-resistant Chinese hamster cells: implications for mechanisms regulating metallothionein gene expression. Mol Cell Biol (1985) 1.23
Coordinate expression of amplified metallothionein I and II genes in cadmium-resistant Chinese hamster cells. Mol Cell Biol (1985) 0.84
Effects of ultraviolet irradiation and postirradiation incubation on heterogenous nuclear RNA size in murine cells. Biophys J (1978) 0.84
DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell (1985) 7.62
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res (2001) 4.47
Preferential DNA repair of an active gene in human cells. Proc Natl Acad Sci U S A (1986) 3.42
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity. J Biol Chem (2000) 3.17
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep (2000) 2.88
Functional and physical interaction between WRN helicase and human replication protein A. J Biol Chem (1999) 2.77
Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene. Proc Natl Acad Sci U S A (1986) 2.29
Ku complex interacts with and stimulates the Werner protein. Genes Dev (2000) 2.21
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO J (2001) 2.21
Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos. Cell (1986) 2.13
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer Res (2001) 2.04
Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem (1997) 2.02
Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J Exp Med (1998) 2.00
Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells. Carcinogenesis (1992) 1.92
Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO. Nucleic Acids Res (1999) 1.90
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Natl Acad Sci U S A (1998) 1.86
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc Natl Acad Sci U S A (1997) 1.74
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair. J Biol Chem (2000) 1.66
Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair. J Biol Chem (1999) 1.65
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair. Biochemistry (2001) 1.56
DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci U S A (1995) 1.56
Mitochondrial DNA repair pathways. Mutat Res (1999) 1.53
Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts. J Biol Chem (1998) 1.52
Characterization of a DNA repair domain containing the dihydrofolate reductase gene in Chinese hamster ovary cells. J Biol Chem (1986) 1.51
Deficient DNA repair capacity, a predisposing factor in breast cancer. Br J Cancer (1996) 1.46
ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients. J Natl Cancer Inst (1992) 1.46
DNA repair, mitochondria, and neurodegeneration. Neuroscience (2006) 1.41
Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines. Mol Cell Biol (1992) 1.39
Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA. EMBO J (2001) 1.37
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA. J Biol Chem (2001) 1.37
An oxidative damage-specific endonuclease from rat liver mitochondria. J Biol Chem (1997) 1.36
Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin. J Biol Chem (1991) 1.32
Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells. J Biol Chem (1991) 1.32
Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein. J Biol Chem (2001) 1.32
Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis. Mol Biol Cell (1997) 1.31
Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes. Immunology (2001) 1.30
Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. Nucleic Acids Res (1999) 1.30
The Werner syndrome protein is involved in RNA polymerase II transcription. Mol Biol Cell (1999) 1.29
Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein. Nucleic Acids Res (1997) 1.28
Age-associated change in mitochondrial DNA damage. Free Radic Res (1998) 1.28
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res (2000) 1.26
Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases. J Biol Chem (2000) 1.25
A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism. Carcinogenesis (2000) 1.21
Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria. Nucleic Acids Res (1999) 1.21
Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands. Biochemistry (2001) 1.20
The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity. Nucleic Acids Res (2004) 1.19
Base excision repair in nuclear and mitochondrial DNA. Prog Nucleic Acid Res Mol Biol (2001) 1.18
Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells. J Biol Chem (1989) 1.18
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA. Nucleic Acids Res (2000) 1.17
Reduced RNA polymerase II transcription in extracts of cockayne syndrome and xeroderma pigmentosum/Cockayne syndrome cells. Nucleic Acids Res (1997) 1.15
DNA base excision repair in human malaria parasites is predominantly by a long-patch pathway. Biochemistry (2000) 1.14
Quantification of aminofluorene adduct formation and repair in defined DNA sequences in mammalian cells using the UVRABC nuclease. J Biol Chem (1989) 1.14
General method for quantifying base adducts in specific mammalian genes. Proc Natl Acad Sci U S A (1988) 1.13
Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction. Nucleic Acids Res (2005) 1.13
Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis. Free Radic Biol Med (2009) 1.12
A UV-responsive G2 checkpoint in rodent cells. Mol Cell Biol (1995) 1.11
Genomic heterogeneity of nucleotide excision repair. Gene (2000) 1.08
The C-terminal domain of p21 inhibits nucleotide excision repair In vitro and In vivo. Mol Biol Cell (1999) 1.08
p53 Modulates the exonuclease activity of Werner syndrome protein. J Biol Chem (2001) 1.07
Impact of DNA polymorphisms in key DNA base excision repair proteins on cancer risk. Hum Exp Toxicol (2012) 1.07
Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts. Nucleic Acids Res (1999) 1.06
Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells. J Biol Chem (1990) 1.06
Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis. Oncogene (2000) 1.06
No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free Radic Biol Med (2005) 1.06
Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide. Cancer Res (1992) 1.05
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA. Nucleic Acids Res (2001) 1.05
Mitochondrial endogenous oxidative damage has been overestimated. FASEB J (2000) 1.05
Repair of individual DNA strands in the hamster dihydrofolate reductase gene after treatment with ultraviolet light, alkylating agents, and cisplatin. J Biol Chem (1993) 1.04
Single nucleotide patch base excision repair is the major pathway for removal of thymine glycol from DNA in human cell extracts. J Biol Chem (2000) 1.03
Accelerated methylation of ribosomal RNA genes during the cellular senescence of Werner syndrome fibroblasts. FASEB J (2000) 1.02
DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts. Free Radic Biol Med (2001) 1.02
Inhibition of RNA polymerase II transcription in human cell extracts by cisplatin DNA damage. Biochemistry (1999) 1.02
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair. Mol Biol Cell (1999) 1.00
Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage. Nucleic Acids Res (1994) 0.99
Gene-specific nuclear and mitochondrial repair of formamidopyrimidine DNA glycosylase-sensitive sites in Chinese hamster ovary cells. Mutat Res (1996) 0.99
Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features. J Biol Chem (1993) 0.99
Gene-specific DNA repair of UV-induced cyclobutane pyrimidine dimers in some cancer-prone and premature-aging human syndromes. Mutat Res (1994) 0.99
Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cells. Mol Cell Biol (1989) 0.99
Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction. FASEB J (2004) 0.98
Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle. Mol Cell Biol (1995) 0.98
DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA. Nucleic Acids Res (2004) 0.97
DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice. Mol Cell Biol (1991) 0.96
Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells. Nucleic Acids Res (1999) 0.96
Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA. Nucleic Acids Res (1998) 0.96
Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain. J Mol Biol (1999) 0.95
Telomere reduction and telomerase inactivation during neuronal cell differentiation. Biochem Biophys Res Commun (1996) 0.95
Relationship between DNA cross-links, cell cycle, and apoptosis in Burkitt's lymphoma cell lines differing in sensitivity to nitrogen mustard. Cancer Res (1991) 0.95
DNA repair at the level of the gene. Trends Biochem Sci (1988) 0.95
DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria. Cancer Res (1998) 0.94
Efficient PCNA complex formation is dependent upon both transcription coupled repair and genome overall repair. Mutat Res (1998) 0.94
Human diseases deficient in RecQ helicases. Biochimie (2003) 0.94
The human CSB (ERCC6) gene corrects the transcription-coupled repair defect in the CHO cell mutant UV61. Nucleic Acids Res (1996) 0.94
Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice. Am J Pathol (2001) 0.93
Impact of age on hypermutation of immunoglobulin variable genes in humans. J Clin Immunol (2001) 0.92
Enhanced repair of pyrimidine dimers in coding and non-coding genomic sequences in CHO cells expressing a prokaryotic DNA repair gene. Carcinogenesis (1987) 0.92
Deficient gene specific repair of cisplatin-induced lesions in Xeroderma pigmentosum and Fanconi's anemia cell lines. Carcinogenesis (1993) 0.91
Measurement of oxidatively induced base lesions in liver from Wistar rats of different ages. Free Radic Biol Med (1999) 0.91
DNA repair of pyrimidine dimers and 6-4 photoproducts in the ribosomal DNA. Nucleic Acids Res (1999) 0.91
DNA strand-specific repair of (+-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene adducts in the hamster dihydrofolate reductase gene. Proc Natl Acad Sci U S A (1992) 0.91
DNA strand bias in the repair of the p53 gene in normal human and xeroderma pigmentosum group C fibroblasts. Cancer Res (1993) 0.90