Published in Trends Microbiol on September 01, 1995
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev (1996) 13.91
A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria. Cell Host Microbe (2010) 4.98
Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions. PLoS Pathog (2010) 3.15
Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. J Bacteriol (1996) 2.43
Clinical significance of microbial infection and adaptation in cystic fibrosis. Clin Microbiol Rev (2011) 2.23
Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J Bacteriol (1996) 2.13
The Pseudomonas aeruginosa secreted protein PA2934 decreases apical membrane expression of the cystic fibrosis transmembrane conductance regulator. Infect Immun (2007) 1.78
Applications of flow cytometry to clinical microbiology. Clin Microbiol Rev (2000) 1.69
The Pseudomonas aeruginosa ribbon-helix-helix DNA-binding protein AlgZ (AmrZ) controls twitching motility and biogenesis of type IV pili. J Bacteriol (2006) 1.63
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection. ISME J (2011) 1.59
Cystic fibrosis lung disease: genetic influences, microbial interactions, and radiological assessment. Pediatr Radiol (2005) 1.48
Acquisition and evolution of the exoU locus in Pseudomonas aeruginosa. J Bacteriol (2006) 1.40
Alginate synthesis in Pseudomonas aeruginosa: the role of AlgL (alginate lyase) and AlgX. J Bacteriol (1996) 1.32
Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE). Infect Immun (1996) 1.31
Role of the two-component regulator CpxAR in the virulence of Salmonella enterica serotype Typhimurium. Infect Immun (2004) 1.30
Global genomic analysis of AlgU (sigma(E))-dependent promoters (sigmulon) in Pseudomonas aeruginosa and implications for inflammatory processes in cystic fibrosis. J Bacteriol (2002) 1.29
Cif is negatively regulated by the TetR family repressor CifR. Infect Immun (2008) 1.27
The alternative sigma factor AlgT represses Pseudomonas aeruginosa flagellum biosynthesis by inhibiting expression of fleQ. J Bacteriol (2005) 1.26
Bacterial two-hybrid analysis of interactions between region 4 of the sigma(70) subunit of RNA polymerase and the transcriptional regulators Rsd from Escherichia coli and AlgQ from Pseudomonas aeruginosa. J Bacteriol (2001) 1.17
Biosynthesis of pyochelin and dihydroaeruginoic acid requires the iron-regulated pchDCBA operon in Pseudomonas aeruginosa. J Bacteriol (1997) 1.15
Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation. Infect Immun (2007) 1.11
Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs-A Review. Pathogens (2014) 1.05
Recovery of birth weight z score within 2 years of diagnosis is positively associated with pulmonary status at 6 years of age in children with cystic fibrosis. Pediatrics (2009) 1.03
Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence. Infect Immun (2000) 0.99
Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa. J Bacteriol (1997) 0.97
Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post-transcriptionally regulated. Environ Microbiol (2012) 0.95
SuhB is a regulator of multiple virulence genes and essential for pathogenesis of Pseudomonas aeruginosa. MBio (2013) 0.94
Molecular mechanisms of master regulator VqsM mediating quorum-sensing and antibiotic resistance in Pseudomonas aeruginosa. Nucleic Acids Res (2014) 0.87
Phenotypic and genotypic characterization of Pseudomonas aeruginosa from cystic fibrosis patients. Eur J Clin Microbiol Infect Dis (2008) 0.86
Pseudomonas aeruginosa AlgR controls cyanide production in an AlgZ-dependent manner. J Bacteriol (2009) 0.86
The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol (2012) 0.83
Polynucleotide Phosphorylase Regulates Multiple Virulence Factors and the Stabilities of Small RNAs RsmY/Z in Pseudomonas aeruginosa. Front Microbiol (2016) 0.79
Influence of the Photorhabdus luminescens phosphomannose isomerase gene, manA, on mannose utilization, exopolysaccharide structure, and biofilm formation. Appl Environ Microbiol (2010) 0.76
Modulation of Type III Secretion System in Pseudomonas aeruginosa: Involvement of the PA4857 Gene Product. Front Microbiol (2016) 0.75
Exploring the role and diversity of mucins in health and disease with special insight into non-communicable diseases. Glycoconj J (2015) 0.75
GENIES: a natural-language processing system for the extraction of molecular pathways from journal articles. Bioinformatics (2001) 6.05
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev (1998) 5.96
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. Dev Cell (2001) 5.82
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell (1998) 5.28
Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients. Proc Natl Acad Sci U S A (1993) 4.78
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature (2000) 4.68
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nat Genet (2000) 4.57
Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science (1994) 4.57
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene (2001) 3.96
Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation (1992) 3.73
Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees. Proc Natl Acad Sci U S A (1998) 3.35
Role of the Kv4.3 K+ channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res (1996) 3.23
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res Mol Brain Res (1997) 3.21
Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors. J Bacteriol (1994) 3.15
High rate of recombination throughout the human immunodeficiency virus type 1 genome. J Virol (2000) 3.09
Distribution of orexin receptor mRNA in the rat brain. FEBS Lett (1998) 2.90
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet (2001) 2.84
Nucleotide sequence of a ripening-related cDNA from avocado fruit. Plant Mol Biol (1990) 2.53
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat Struct Biol (2000) 2.49
Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circ Res (1999) 2.47
Case study of the effects of atmospheric aerosols and regional haze on agriculture: an opportunity to enhance crop yields in China through emission controls? Proc Natl Acad Sci U S A (1999) 2.44
Nonoperative management of blunt hepatic trauma is the treatment of choice for hemodynamically stable patients. Results of a prospective trial. Ann Surg (1995) 2.43
Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. J Bacteriol (1996) 2.43
Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response. J Bacteriol (1994) 2.37
Mechanism of antigenic variation in Mycoplasma pulmonis: interwoven, site-specific DNA inversions. Mol Microbiol (1995) 2.26
PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Nucleic Acids Res (2001) 2.23
Differentiation of Pseudomonas aeruginosa into the alginate-producing form: inactivation of mucB causes conversion to mucoidy. Mol Microbiol (1993) 2.22
Sequence analysis of ripening-related cytochrome P-450 cDNAs from avocado fruit. Proc Natl Acad Sci U S A (1990) 2.17
Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection. Infect Immun (1997) 2.14
Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13
Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J Bacteriol (1996) 2.13
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res (1999) 2.09
Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4. Immunity (1998) 2.08
Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. Proc Natl Acad Sci U S A (2007) 2.05
Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. Thorax (1998) 2.04
Beyond synexpression relationships: local clustering of time-shifted and inverted gene expression profiles identifies new, biologically relevant interactions. J Mol Biol (2001) 2.03
Pharmacological characterization of recombinant human and rat P2X receptor subtypes. Eur J Pharmacol (1999) 1.95
Kinectin, a major kinesin-binding protein on ER. J Cell Biol (1992) 1.87
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice. Transgenic Res (2000) 1.83
Functional equivalence of Escherichia coli sigma E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa. J Bacteriol (1995) 1.83
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro. Mol Cell Biol (1985) 1.81
Alpha-1-microglobulin: an indicator protein for renal tubular function. J Clin Pathol (1983) 1.80
Identification of a lipid transfer protein as the major protein in the surface wax of broccoli (Brassica oleracea) leaves. Arch Biochem Biophys (1994) 1.79
Organisation of the tomato polyphenol oxidase gene family. Plant Mol Biol (1993) 1.74
GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells. Immunity (2001) 1.73
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology (2006) 1.73
Directly labeled DNA probes using fluorescent nucleotides with different length linkers. Nucleic Acids Res (1994) 1.71
Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa. J Bacteriol (1995) 1.69
Human infection with avian influenza A(H7N9) virus re-emerges in China in winter 2013. Euro Surveill (2013) 1.68
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression. Neuron (1998) 1.64
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research. Breast Cancer Res Treat (1995) 1.63
Identification of receptors for neuromedin U and its role in feeding. Nature (2000) 1.60
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. Mol Biol Cell (2001) 1.59
Natural killer cells from HIV-1+ patients produce C-C chemokines and inhibit HIV-1 infection. J Immunol (1998) 1.59
Renal proximal dysfunction in patients with rheumatic diseases. Br Med J (Clin Res Ed) (1984) 1.57
Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor. Mol Pharmacol (1992) 1.57
Cellular protein modulates effects of human immunodeficiency virus type 1 Rev. J Virol (1994) 1.56
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. J Clin Invest (2001) 1.55
Kinectin, an essential anchor for kinesin-driven vesicle motility. Science (1995) 1.54
Planned ventral hernia. Staged management for acute abdominal wall defects. Ann Surg (1994) 1.54
CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1. Curr Biol (1996) 1.52
Prostate-specific antigen levels in nipple aspirate fluid correlate with breast cancer risk. Cancer Epidemiol Biomarkers Prev (1996) 1.52
Gene rearrangements in the vsa locus of Mycoplasma pulmonis. J Bacteriol (2000) 1.50
Combining low tube voltage and iterative reconstruction for contrast-enhanced CT imaging of the chest-initial clinical experience. Clin Radiol (2013) 1.50
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential. Oncogene (1997) 1.48
Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a. J Biol Chem (2001) 1.47
Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. Am J Hum Genet (2000) 1.47
Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation. Science (2000) 1.46
cDNA sequence for human erythrocyte ankyrin. Proc Natl Acad Sci U S A (1990) 1.46
Regulation of a restriction and modification system via DNA inversion in Mycoplasma pulmonis. Mol Microbiol (1994) 1.46
Nicastrin binds to membrane-tethered Notch. Nat Cell Biol (2001) 1.44
TP53 codon 72 polymorphism with hepatocellular carcinoma: a metaanalysis. J Int Med Res (2012) 1.43
Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Mol Microbiol (2000) 1.43
Structure of the PI3K SH3 domain and analysis of the SH3 family. Cell (1993) 1.42
Addressing phase errors in fat-water imaging using a mixed magnitude/complex fitting method. Magn Reson Med (2011) 1.41
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli. J Biol Chem (1995) 1.40
Purification and characterization of an elastinolytic metalloprotease from Aspergillus fumigatus and immunoelectron microscopic evidence of secretion of this enzyme by the fungus invading the murine lung. Infect Immun (1994) 1.39
Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4). Ann Oncol (2011) 1.36
Control of mitotic transitions by the anaphase-promoting complex. Philos Trans R Soc Lond B Biol Sci (1999) 1.36
Pancreatitis and pancreatic cancer risk: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4). Ann Oncol (2012) 1.35
Characteristics of the m2000 automated sample preparation and multiplex real-time PCR system for detection of Chlamydia trachomatis and Neisseria gonorrhoeae. J Clin Microbiol (2007) 1.33
A549 lung epithelial cells grown as three-dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis. Infect Immun (2005) 1.33
Evidence of altered hypothalamic pro-opiomelanocortin/ neuropeptide Y mRNA expression in tubby mice. Brain Res Mol Brain Res (1998) 1.32
cDNA cloning and expression of potato polyphenol oxidase. Plant Mol Biol (1993) 1.32
MR imaging of articular cartilage at 1.5T and 3.0T: comparison of SPGR and SSFP sequences. Osteoarthritis Cartilage (2005) 1.32
Methylation of the human telomerase gene CpG island. Cancer Res (2000) 1.31
Mechanisms of bacterial pathogenicity. Postgrad Med J (2002) 1.29
Circulating endothelial microparticles in acute ischemic stroke: a link to severity, lesion volume and outcome. J Thromb Haemost (2006) 1.29
Patient compliance is critical for equivalent clinical outcomes for breast cancer treated by breast-conservation therapy. Ann Surg (2000) 1.28
GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron (2001) 1.27
Rapid, accurate determination of multidrug resistance in M. tuberculosis isolates and sputum using a biochip system. Int J Tuberc Lung Dis (2009) 1.27
Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway. Br J Cancer (2008) 1.26
Uterine artery embolisation combined with local methotrexate for treatment of caesarean scar pregnancy. BJOG (2010) 1.25
Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity. Microbiology (1997) 1.24
Developmental change in the voltage-dependence of the pacemaker current, if, in rat ventricle cells. Pflugers Arch (1997) 1.23