Published in J Biol Chem on January 19, 1996
beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J (1997) 12.97
Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol (2000) 4.36
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. Genes Dev (2000) 2.67
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. Mol Cell Biol (2003) 2.58
NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J Cell Biol (1997) 2.42
Structure and biochemistry of cadherins and catenins. Cold Spring Harb Perspect Biol (2009) 2.37
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling. J Cell Biol (1996) 2.09
The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes. J Cell Biol (1997) 1.93
Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol Biol Cell (1998) 1.87
Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion. J Cell Biol (1998) 1.84
AlphaE-catenin regulates actin dynamics independently of cadherin-mediated cell-cell adhesion. J Cell Biol (2010) 1.81
Molecular components of the adherens junction. Biochim Biophys Acta (2008) 1.78
Epicardium-derived progenitor cells require beta-catenin for coronary artery formation. Proc Natl Acad Sci U S A (2007) 1.72
Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein. Proc Natl Acad Sci U S A (1998) 1.72
Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex. J Cell Biol (1996) 1.69
beta-Catenin regulates excitatory postsynaptic strength at hippocampal synapses. Proc Natl Acad Sci U S A (2007) 1.54
Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des (2013) 1.44
Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription. Mol Cell Biol (2003) 1.33
Biochemical and structural analysis of alpha-catenin in cell-cell contacts. Biochem Soc Trans (2008) 1.32
Roles of the C terminus of Armadillo in Wingless signaling in Drosophila. Genetics (1999) 1.32
The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells. Proc Natl Acad Sci U S A (2006) 1.27
A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells. J Cell Biol (2002) 1.19
Antagonism of cell adhesion by an alpha-catenin mutant, and of the Wnt-signaling pathway by alpha-catenin in Xenopus embryos. J Cell Biol (1997) 1.18
Plakoglobin: role in tumorigenesis and metastasis. Int J Cell Biol (2012) 1.15
Beta-catenin interacts with MyoD and regulates its transcription activity. Mol Cell Biol (2008) 1.06
Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila. J Cell Biol (1998) 1.00
Protein 4.1R links E-cadherin/beta-catenin complex to the cytoskeleton through its direct interaction with beta-catenin and modulates adherens junction integrity. Biochim Biophys Acta (2009) 0.99
Novel membrane protein shrew-1 targets to cadherin-mediated junctions in polarized epithelial cells. Mol Biol Cell (2003) 0.98
NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation. Oncogene (2010) 0.97
Catenin-dependent cadherin function drives divisional segregation of spinal motor neurons. J Neurosci (2012) 0.93
beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation. Mol Cell Biol (2004) 0.92
The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1. Proc Natl Acad Sci U S A (2006) 0.90
Structural and thermodynamic characterization of cadherin·β-catenin·α-catenin complex formation. J Biol Chem (2014) 0.89
Beyond cell adhesion: the role of armadillo proteins in the heart. Cell Signal (2012) 0.89
Flotillins directly interact with γ-catenin and regulate epithelial cell-cell adhesion. PLoS One (2013) 0.88
Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo. Proc Natl Acad Sci U S A (2014) 0.84
The evolutionary origin of epithelial cell-cell adhesion mechanisms. Curr Top Membr (2013) 0.84
Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions. Mol Cell Proteomics (2011) 0.83
Parallel duplication and partial subfunctionalization of β-catenin/armadillo during insect evolution. Mol Biol Evol (2011) 0.82
Wingless signalling alters the levels, subcellular distribution and dynamics of Armadillo and E-cadherin in third instar larval wing imaginal discs. PLoS One (2008) 0.82
Beta-catenin phosphorylated at threonine 120 antagonizes generation of active beta-catenin by spatial localization in trans-Golgi network. PLoS One (2012) 0.82
Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation. Elife (2015) 0.81
Cell adhesion and migration in the organization of spinal motor neurons. Cell Adh Migr (2012) 0.81
Functional inhibition of β-catenin-mediated Wnt signaling by intracellular VHH antibodies. MAbs (2015) 0.80
4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin. J Cell Mol Med (2009) 0.77
A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway. Cell Discov (2016) 0.77
Protein phosphatase 2A activity is required for functional adherent junctions in endothelial cells. Microvasc Res (2013) 0.76
The role of adherens junctions in the developing neocortex. Cell Adh Migr (2015) 0.76
Characterization of the Cadherin-Catenin Complex of the Sea Anemone Nematostella vectensis and Implications for the Evolution of Metazoan Cell-Cell Adhesion. Mol Biol Evol (2016) 0.75
Redistribution of beta-catenin in response to EGF and lithium signalling in human oesophageal squamous carcinoma cell lines. Cancer Cell Int (2003) 0.75
Evolution and cell physiology. 3. Using Dictyostelium discoideum to investigate mechanisms of epithelial polarity. Am J Physiol Cell Physiol (2013) 0.75
Structural and functional characterization of the α-catenin·β-catenin binding interface in Caenorhabditis elegans reveals conserved requirements for cell-cell adhesion in metazoans. J Biol Chem (2017) 0.75
beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J (1997) 12.97
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol (1985) 12.74
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J (1989) 10.05
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (2001) 9.00
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells. J Cell Biol (1985) 6.09
Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci U S A (1990) 5.83
E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc Natl Acad Sci U S A (1994) 5.31
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech Dev (1996) 5.13
Lack of beta-catenin affects mouse development at gastrulation. Development (1995) 4.95
Assembly of the cadherin-catenin complex in vitro with recombinant proteins. J Cell Sci (1994) 4.81
Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol (1994) 4.46
A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene. Cell (1986) 4.39
A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2-specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis. Rofecoxib Osteoarthritis Endoscopy Study Group. Gastroenterology (1999) 4.13
Cadherin-catenin complex: protein interactions and their implications for cadherin function. J Cell Biochem (1996) 3.95
Identification of a putative cell adhesion domain of uvomorulin. EMBO J (1985) 3.85
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J (2000) 3.77
Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell (1990) 3.75
Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis (2000) 3.71
The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. Proc Natl Acad Sci U S A (1991) 3.62
E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J Cell Sci (1999) 3.55
Molecular organization of the uvomorulin-catenin complex. J Cell Biol (1992) 3.46
Rabbit antiserum against a purified surface glycoprotein decompacts mouse preimplantation embryos and reacts with specific adult tissues. Exp Cell Res (1984) 3.20
Transgenesis by means of blastocyst-derived embryonic stem cell lines. Proc Natl Acad Sci U S A (1986) 3.11
Surface antigen in early differentiation. Proc Natl Acad Sci U S A (1977) 2.83
Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev Biol (1987) 2.72
Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine. Development (2000) 2.59
Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation. Proc Natl Acad Sci U S A (1980) 2.49
Plakoglobin and beta-catenin: distinct but closely related. Science (1992) 2.40
A role for cadherins in tissue formation. Development (1996) 2.32
Cell-matrix interactions and cell adhesion during development. Annu Rev Cell Biol (1986) 2.28
A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Adhes Commun (1994) 2.27
Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur J Biochem (1994) 2.23
An acute clinical trial evaluating the cardiovascular effects of an herbal ephedra-caffeine weight loss product in healthy overweight adults. Int J Obes Relat Metab Disord (2002) 2.16
Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity. EMBO J (2000) 2.15
Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin. J Cell Biol (1990) 2.14
Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody. J Biol Chem (1998) 2.14
Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development (1988) 2.12
Cadherins and catenins in development. Curr Opin Cell Biol (1996) 2.11
Cadherins and tissue formation: integrating adhesion and signaling. Bioessays (1999) 2.05
An alpha-E-catenin gene trap mutation defines its function in preimplantation development. Proc Natl Acad Sci U S A (1997) 2.05
Reactivity of monoclonal antibodies against intermediate filament proteins during embryonic development. J Embryol Exp Morphol (1981) 2.04
Embryonic heart and skin defects in mice lacking plakoglobin. Dev Biol (1996) 2.01
Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro. J Biol Chem (1999) 1.98
Some structural and functional aspects of the cell adhesion molecule uvomorulin. Cell Differ (1984) 1.98
Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function. Cell (1990) 1.98
The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity. J Cell Biol (1998) 1.97
Brachyury is a target gene of the Wnt/beta-catenin signaling pathway. Mech Dev (2000) 1.91
Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion. J Biol Chem (2000) 1.90
Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression. EMBO Rep (2000) 1.84
Role of beta-catenin in the developing cortical and hippocampal neuroepithelium. Neuroscience (2003) 1.78
Cell-adhesion molecule uvomorulin during kidney development. Dev Biol (1985) 1.76
Altered cell adhesion activity by pervanadate due to the dissociation of alpha-catenin from the E-cadherin.catenin complex. J Biol Chem (1998) 1.74
Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein. Proc Natl Acad Sci U S A (1998) 1.72
Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1. Proc Natl Acad Sci U S A (1999) 1.69
The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis. Mech Dev (1999) 1.61
The association of protein with the polyadenylic acid of HeLa cell messenger RNA: evidence for a "transport" role of a 75,000 molecular weight polypeptide. J Mol Biol (1976) 1.58
Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin. Differentiation (1988) 1.55
Seven-day therapy for Helicobacter pylori in the United States. Aliment Pharmacol Ther (2004) 1.53
Chicken soup rebound and relapse of pneumonia: report of a case. Chest (1975) 1.50
Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities. Cell Growth Differ (1991) 1.49
Uvomorulin-catenin complex: cytoplasmic anchorage of a Ca2+-dependent cell adhesion molecule. Bioessays (1989) 1.48
Distinct cadherin-catenin complexes in Ca(2+)-dependent cell-cell adhesion. FEBS Lett (1994) 1.46
Molecular cloning and characterization of the human E-cadherin cDNA. Mol Biol Rep (1993) 1.45
An endoscopic comparison of the effects of alendronate and risedronate on upper gastrointestinal mucosae. Am J Gastroenterol (2000) 1.44
Alterations in beta-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res (1994) 1.43
Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet (1998) 1.39
Abraham Lincoln and cardiac decompensation: a preliminary report. West J Med (1978) 1.38
Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines. J Exp Med (1978) 1.38
Abraham Lincoln and aortic insufficiency. The declining health of the President. Calif Med (1972) 1.36
The structure of the gene coding for the mouse cell adhesion molecule uvomorulin. Nucleic Acids Res (1991) 1.34
Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene. Mech Dev (1997) 1.34
Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. Development (1999) 1.33
Expression patterns of Wnt genes in mouse gut development. Mech Dev (2001) 1.27
The promastigote surface protease (gp63) of Leishmania is expressed but differentially processed and localized in the amastigote stage. Mol Biochem Parasitol (1989) 1.27
A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin. J Cell Sci (1997) 1.26
Simple and efficient production of embryonic stem cell-embryo chimeras by coculture. Proc Natl Acad Sci U S A (1993) 1.25
DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard. Cancer Res (1981) 1.25
Evidence from UV transcription mapping in HeLa cells that heterogeneous nuclear RNA is the messenger RNA precursor. Proc Natl Acad Sci U S A (1977) 1.24
A possible new adhesive site in the cell-adhesion molecule uvomorulin. Mech Dev (1990) 1.23
Expression of Eph receptors and ephrins is differentially regulated by E-cadherin. J Cell Sci (2000) 1.22
Chromosomal mapping of the structural gene coding for the mouse cell adhesion molecule uvomorulin. Proc Natl Acad Sci U S A (1988) 1.19
Cell-junctional and cytoskeletal organization in mouse blastocysts lacking E-cadherin. Dev Biol (1997) 1.14
Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia? Am J Med (1983) 1.14
Mutations affecting transmembrane segment interactions impair adhesiveness of E-cadherin. J Cell Sci (1999) 1.14
Congenital aneurysm of the left sinus of Valsalva. Report of a patient with 19-year survival without surgery. Chest (1986) 1.12
Relationship between glucose and fatty acid in myocardial infarction. Lancet (1966) 1.11
Absence of a serologically detectable association of murine beta2-microglobulin with the embryonic F9 antigen. Transplantation (1976) 1.11
Age-related changes in the redox status of rat muscle cells and their role in enzyme-aging. Mech Ageing Dev (1985) 1.09
Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence. Proc Natl Acad Sci U S A (1986) 1.08
N-cadherin in adult rat cardiomyocytes in culture. II. Spatio-temporal appearance of proteins involved in cell-cell contact and communication. Formation of two distinct N-cadherin/catenin complexes. J Cell Sci (1996) 1.06
Expression and cell membrane localization of catenins during mouse preimplantation development. Dev Dyn (1996) 1.05
Temporal evolution of the human coronary collateral circulation after myocardial infarction. J Am Coll Cardiol (1984) 1.01
Beta-catenin is a major tyrosine-phosphorylated protein during mouse oocyte maturation and preimplantation development. Dev Dyn (1999) 1.00
Expression of the cytoplasmic domain of E-cadherin induces precocious mammary epithelial alveolar formation and affects cell polarity and cell-matrix integrity. Dev Biol (1999) 0.99
A potential role of R-cadherin in striated muscle formation. Dev Biol (1997) 0.98
Comparison of two cell-adhesion molecules, uvomorulin and cell-CAM 105. Exp Cell Res (1985) 0.98
Embryonal carcinoma antigen and the T/t locus of the mouse. Proc Natl Acad Sci U S A (1976) 0.98
A PCR method for introducing mutations into cloned DNA by joining an internal primer to a tagged flanking primer. Nucleic Acids Res (1992) 0.97