Published in Cell on April 19, 1996
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev (1996) 13.91
Lung infections associated with cystic fibrosis. Clin Microbiol Rev (2002) 9.20
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol (1997) 7.51
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest (2002) 6.35
Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest (2002) 5.94
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function. J Bacteriol (2001) 4.09
Production of beta-defensins by human airway epithelia. Proc Natl Acad Sci U S A (1998) 3.85
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A (1998) 3.83
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest (1998) 3.51
Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infection. Infect Immun (1998) 3.43
Coordinated clearance of periciliary liquid and mucus from airway surfaces. J Clin Invest (1998) 3.30
A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients. Proc Natl Acad Sci U S A (2008) 3.28
characterization of bacterial community diversity in cystic fibrosis lung infections by use of 16s ribosomal DNA terminal restriction fragment length polymorphism profiling. J Clin Microbiol (2004) 3.28
A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J (1998) 3.13
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature (2012) 2.94
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins. Proc Natl Acad Sci U S A (1998) 2.68
A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med (2006) 2.61
Staphylococcus aureus RN6390 replicates and induces apoptosis in a pulmonary epithelial cell line. Infect Immun (2000) 2.54
Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo. J Clin Invest (1998) 2.51
Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung. Proc Natl Acad Sci U S A (1997) 2.51
Epithelial antimicrobial peptides in host defense against infection. Respir Res (2000) 2.40
Drosophila as a model host for Pseudomonas aeruginosa infection. J Bacteriol (2001) 2.36
Phylogenetic and metabolic diversity of bacteria associated with cystic fibrosis. ISME J (2010) 2.33
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3. Proc Natl Acad Sci U S A (2003) 2.32
The Pseudomonas aeruginosa flagellar cap protein, FliD, is responsible for mucin adhesion. Infect Immun (1998) 2.29
The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition. J Gen Physiol (2001) 2.28
Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest (1999) 2.24
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sci U S A (1997) 2.24
Clinical significance of microbial infection and adaptation in cystic fibrosis. Clin Microbiol Rev (2011) 2.23
The genesis of cystic fibrosis lung disease. J Clin Invest (1999) 2.23
Innate antimicrobial activity of nasal secretions. Infect Immun (1999) 2.13
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proc Natl Acad Sci U S A (2001) 2.10
Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa. J Clin Invest (1997) 2.10
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci U S A (2004) 2.09
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility. J Bacteriol (1999) 2.09
Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). J Cyst Fibros (2007) 2.07
Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J Clin Invest (1998) 2.05
Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc Natl Acad Sci U S A (1998) 1.96
The innate immune system in cystic fibrosis lung disease. J Clin Invest (1999) 1.93
Effects of the twin-arginine translocase on secretion of virulence factors, stress response, and pathogenesis. Proc Natl Acad Sci U S A (2002) 1.88
Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells. J Gen Physiol (1999) 1.88
Expression of the peptide antibiotic human beta-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infect Immun (1998) 1.86
Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia. J Clin Invest (2000) 1.82
Interaction of pseudomonas aeruginosa with epithelial cells: identification of differentially regulated genes by expression microarray analysis of human cDNAs. Proc Natl Acad Sci U S A (2000) 1.81
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest (2001) 1.80
Salt-resistant alpha-helical cationic antimicrobial peptides. Antimicrob Agents Chemother (1999) 1.78
Effects of pH and salinity on the antimicrobial properties of clavanins. Infect Immun (1997) 1.75
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J Clin Invest (1998) 1.71
Antimicrobial polypeptides in host defense of the respiratory tract. J Clin Invest (2002) 1.67
Mouse beta-defensin 1 is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract. Infect Immun (1998) 1.59
Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. J Bacteriol (2002) 1.58
Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infect Immun (1999) 1.58
beta-Defensin 1 contributes to pulmonary innate immunity in mice. Infect Immun (2002) 1.57
Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. J Clin Invest (1999) 1.50
Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis. J Clin Invest (2007) 1.50
Characterization of the mouse beta defensin 1, Defb1, mutant mouse model. Infect Immun (2002) 1.49
Cystic fibrosis lung disease: genetic influences, microbial interactions, and radiological assessment. Pediatr Radiol (2005) 1.48
Burkholderia cepacia produces a hemolysin that is capable of inducing apoptosis and degranulation of mammalian phagocytes. Infect Immun (1998) 1.47
A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans. PLoS Pathog (2011) 1.47
Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. J Clin Invest (1999) 1.46
Lung disease in mice with cystic fibrosis. J Clin Invest (1997) 1.44
Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis. Thorax (1997) 1.44
Antimicrobial peptides: natural effectors of the innate immune system. Semin Immunopathol (2007) 1.43
Expression analysis of a highly adherent and cytotoxic small colony variant of Pseudomonas aeruginosa isolated from a lung of a patient with cystic fibrosis. J Bacteriol (2004) 1.43
Human airway mucin glycosylation: a combinatory of carbohydrate determinants which vary in cystic fibrosis. Glycoconj J (2001) 1.40
Infection of primary human bronchial epithelial cells by Haemophilus influenzae: macropinocytosis as a mechanism of airway epithelial cell entry. Infect Immun (1999) 1.36
Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro. Am J Pathol (1998) 1.31
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation. Proc Natl Acad Sci U S A (1998) 1.31
Regulation of the depth and composition of airway surface liquid. J Anat (2002) 1.29
Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity. Infect Immun (1999) 1.28
Glucose depletion in the airway surface liquid is essential for sterility of the airways. PLoS One (2011) 1.26
Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor. J Cell Biol (1998) 1.26
Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections. Proc Natl Acad Sci U S A (2000) 1.26
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. J Clin Invest (2014) 1.26
Responses of well-differentiated airway epithelial cell cultures from healthy donors and patients with cystic fibrosis to Burkholderia cenocepacia infection. Infect Immun (2004) 1.25
Human {beta}-defensin 2 is expressed and associated with Mycobacterium tuberculosis during infection of human alveolar epithelial cells. Infect Immun (2005) 1.24
The lactoperoxidase system links anion transport to host defense in cystic fibrosis. FEBS Lett (2006) 1.23
Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proc Natl Acad Sci U S A (2011) 1.23
Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3. J Physiol (2002) 1.22
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferase. Biochem J (2002) 1.22
Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis. Trends Mol Med (2008) 1.21
Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo. J Virol (2000) 1.20
Enhanced susceptibility to pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice. Infect Immun (2001) 1.19
Conditions associated with the cystic fibrosis defect promote chronic Pseudomonas aeruginosa infection. Am J Respir Crit Care Med (2014) 1.19
Host defense peptides in the oral cavity and the lung: similarities and differences. J Dent Res (2008) 1.19
Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis. Infect Immun (2000) 1.15
CFTR, mucins, and mucus obstruction in cystic fibrosis. Cold Spring Harb Perspect Med (2012) 1.15
Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes. Proc Natl Acad Sci U S A (1998) 1.14
Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity. Antimicrob Agents Chemother (2010) 1.14
Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells. Proc Natl Acad Sci U S A (2003) 1.13
Sodium chloride increases the ciliary transportability of cystic fibrosis and bronchiectasis sputum on the mucus-depleted bovine trachea. J Clin Invest (1997) 1.13
Cystic fibrosis: a disease of altered protein folding. J Bioenerg Biomembr (1997) 1.12
Microbial pathogenesis in cystic fibrosis: pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Infect Immun (1998) 1.11
Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice. Infect Immun (2005) 1.10
Lung infections. 3. Pseudomonas aeruginosa and other related species. Thorax (1998) 1.08
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis. J Physiol (1997) 1.08
Cystic Fibrosis: The Mechanisms of Pathogenesis of an Inherited Lung Disorder. Drug Discov Today Dis Mech (2007) 1.06
Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function. Am J Physiol Lung Cell Mol Physiol (2009) 1.04
Molecular basis for defective glycosylation and Pseudomonas pathogenesis in cystic fibrosis lung. Proc Natl Acad Sci U S A (2001) 1.04
Airway surface liquid osmolality measured using fluorophore-encapsulated liposomes. J Gen Physiol (2001) 1.04
Bacterial biofilms: a common cause of persistent infections. Science (1999) 40.82
The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science (1998) 19.92
Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol (1994) 17.55
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci U S A (1994) 11.44
Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature (2000) 10.32
Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu Rev Microbiol (1996) 10.26
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature (1992) 8.47
Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol (2003) 8.11
Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J Bacteriol (1985) 7.79
A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1995) 7.66
Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu Rev Genet (2001) 7.63
Gene expression in Pseudomonas aeruginosa biofilms. Nature (2001) 6.70
Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol (1997) 5.93
Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1999) 5.82
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (1991) 5.82
Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1999) 5.58
Structure and function of the CFTR chloride channel. Physiol Rev (1999) 4.82
Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem (1995) 4.39
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells. Nature (1990) 4.26
Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol (2005) 4.12
Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc Natl Acad Sci U S A (2000) 4.00
QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2001) 3.96
Production of beta-defensins by human airway epithelia. Proc Natl Acad Sci U S A (1998) 3.85
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell (1991) 3.75
Control of Vibrio fischeri luminescence gene expression in Escherichia coli by cyclic AMP and cyclic AMP receptor protein. J Bacteriol (1985) 3.58
The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice. Neuron (2001) 3.56
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell (1993) 3.47
Generation of cAMP-activated chloride currents by expression of CFTR. Science (1991) 3.45
Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties. Nature (1993) 3.43
Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein. Proc Natl Acad Sci U S A (1996) 3.35
The mammalian sodium channel BNC1 is required for normal touch sensation. Nature (2000) 3.30
Self perception in bacteria: quorum sensing with acylated homoserine lactones. Curr Opin Microbiol (1998) 3.30
Planktonic marine luminous bacteria: species distribution in the water column. Appl Environ Microbiol (1980) 3.26
Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa. J Bacteriol (1994) 3.24
Putative exopolysaccharide synthesis genes influence Pseudomonas aeruginosa biofilm development. J Bacteriol (2004) 3.21
Nucleoside triphosphates are required to open the CFTR chloride channel. Cell (1991) 3.21
Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. J Biol Chem (2001) 3.15
Expression and characterization of the cystic fibrosis transmembrane conductance regulator. Nature (1990) 3.09
Acyl homoserine-lactone quorum-sensing signal generation. Proc Natl Acad Sci U S A (1999) 3.07
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium. Nature (1988) 3.06
Synergistic binding of the Vibrio fischeri LuxR transcriptional activator domain and RNA polymerase to the lux promoter region. Proc Natl Acad Sci U S A (1994) 3.05
Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners. Proc Natl Acad Sci U S A (2005) 3.05
Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. J Biol Chem (1999) 3.04
Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. Proc Natl Acad Sci U S A (1978) 3.03
Evidence that the N-terminal region of the Vibrio fischeri LuxR protein constitutes an autoinducer-binding domain. J Bacteriol (1995) 3.01
Control of Vibrio fischeri lux gene transcription by a cyclic AMP receptor protein-luxR protein regulatory circuit. J Bacteriol (1988) 3.00
Genetic dissection of DNA binding and luminescence gene activation by the Vibrio fischeri LuxR protein. J Bacteriol (1992) 2.99
Regulation of quorum sensing by RpoS in Pseudomonas aeruginosa. J Bacteriol (2000) 2.94
The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity. J Biol Chem (1995) 2.88
Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs. J Bacteriol (1996) 2.82
Quorum sensing in Burkholderia cepacia: identification of the LuxRI homologs CepRI. J Bacteriol (1999) 2.81
Critical regions of the Vibrio fischeri luxR protein defined by mutational analysis. J Bacteriol (1990) 2.78
The C-terminal region of the Vibrio fischeri LuxR protein contains an inducer-independent lux gene activating domain. Proc Natl Acad Sci U S A (1991) 2.75
Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR. Proc Natl Acad Sci U S A (2004) 2.69
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins. Proc Natl Acad Sci U S A (1998) 2.68
Crypts are the site of intestinal fluid and electrolyte secretion. Science (1982) 2.66
The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing. Mol Microbiol (2004) 2.63
Overproduction and purification of the luxR gene product: Transcriptional activator of the Vibrio fischeri luminescence system. Proc Natl Acad Sci U S A (1987) 2.59
Physical and functional maps of the luminescence gene cluster in an autoinducer-deficient Vibrio fischeri strain isolated from a squid light organ. J Bacteriol (1992) 2.59
Membrane topology of the amiloride-sensitive epithelial sodium channel. J Biol Chem (1994) 2.56
Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. Am J Physiol Lung Cell Mol Physiol (2000) 2.55
Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents. J Gen Physiol (1992) 2.53
Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo. J Clin Invest (1998) 2.51
Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus. J Bacteriol (2000) 2.50
Chemotaxis in Spirochaeta aurantia. J Bacteriol (1977) 2.50
A mouse model for the delta F508 allele of cystic fibrosis. J Clin Invest (1995) 2.48
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. Cell (1995) 2.47
Cell-to-cell signaling in the symbiotic nitrogen-fixing bacterium Rhizobium leguminosarum: autoinduction of a stationary phase and rhizosphere-expressed genes. J Bacteriol (1996) 2.38
Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel. Am J Physiol (1995) 2.38
Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. J Cell Biol (1979) 2.35
Chloride and potassium channels in cystic fibrosis airway epithelia. Nature (1986) 2.34
Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection. J Clin Invest (1997) 2.33
Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell (1998) 2.31
Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc Natl Acad Sci U S A (1991) 2.30
A quorum-sensing system in the free-living photosynthetic bacterium Rhodobacter sphaeroides. J Bacteriol (1997) 2.27
Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2. Mol Cell Biol (1991) 2.25
Bactericidal activity of mammalian cathelicidin-derived peptides. Infect Immun (2000) 2.24
cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia. J Clin Invest (1992) 2.23
A new class of homoserine lactone quorum-sensing signals. Nature (2008) 2.20
Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains. Science (1992) 2.18
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Cloning and expression of a novel human brain Na+ channel. J Biol Chem (1996) 2.14
Quorum sensing in Vibrio fischeri: essential elements for activation of the luminescence genes. J Bacteriol (1997) 2.10
Effect of deleting the R domain on CFTR-generated chloride channels. Science (1991) 2.09
Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel. Am J Physiol (1994) 2.07
Reversible acyl-homoserine lactone binding to purified Vibrio fischeri LuxR protein. J Bacteriol (2004) 2.06
Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes. J Biol Chem (1992) 2.05
Quorum sensing in Vibrio fischeri: elements of the luxl promoter. Mol Microbiol (1999) 2.03
Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation. Biophys J (1994) 1.99
Adenovirus-mediated gene transfer to ciliated airway epithelia requires prolonged incubation time. J Virol (1996) 1.98
Activity of abundant antimicrobials of the human airway. Am J Respir Cell Mol Biol (1999) 1.93
Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia. J Clin Invest (1992) 1.93
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes. J Bacteriol (2001) 1.92
Calcium-activated potassium channels in canine airway smooth muscle. J Physiol (1986) 1.87
A molecular component of the arterial baroreceptor mechanotransducer. Neuron (1998) 1.87