Published in Infect Immun on July 01, 1997
Innate antimicrobial activity of nasal secretions. Infect Immun (1999) 2.13
Determinants of Staphylococcus aureus nasal carriage. Clin Diagn Lab Immunol (2001) 1.80
Salt-resistant alpha-helical cationic antimicrobial peptides. Antimicrob Agents Chemother (1999) 1.78
Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs. PLoS One (2010) 1.38
Antibacterials from the sea. Chemistry (2010) 1.25
Electrical detection of pathogenic bacteria via immobilized antimicrobial peptides. Proc Natl Acad Sci U S A (2010) 1.13
Antimicrobial peptides from marine invertebrates. Antimicrob Agents Chemother (2004) 1.08
Suppression of innate immunity by a nasal carriage strain of Staphylococcus aureus increases its colonization on nasal epithelium. Immunology (2007) 1.01
In vitro microbicidal activities of cecropin peptides D2A21 and D4E1 and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis. Antimicrob Agents Chemother (2002) 0.97
Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae. Mar Drugs (2010) 0.96
Boosting salt resistance of short antimicrobial peptides. Antimicrob Agents Chemother (2013) 0.96
Histidine-rich glycoprotein protects from systemic Candida infection. PLoS Pathog (2008) 0.95
Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat. J Biol Chem (2012) 0.94
Easy strategy to increase salt resistance of antimicrobial peptides. Antimicrob Agents Chemother (2011) 0.93
Biological activities of synthetic analogs of halocidin, an antimicrobial peptide from the tunicate Halocynthia aurantium. Antimicrob Agents Chemother (2003) 0.91
Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide. Ann Clin Microbiol Antimicrob (2007) 0.91
Small changes in the primary structure of transportan 10 alter the thermodynamics and kinetics of its interaction with phospholipid vesicles. Biochemistry (2008) 0.89
Design and characterization of an acid-activated antimicrobial peptide. Chem Biol Drug Des (2009) 0.89
Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. J Am Chem Soc (2014) 0.89
Resurrecting inactive antimicrobial peptides from the lipopolysaccharide trap. Antimicrob Agents Chemother (2014) 0.87
Human macrophage inflammatory protein 3alpha: protein and peptide nuclear magnetic resonance solution structures, dimerization, dynamics, and anti-infective properties. Antimicrob Agents Chemother (2007) 0.87
A novel target-specific, salt-resistant antimicrobial peptide against the cariogenic pathogen Streptococcus mutans. Antimicrob Agents Chemother (2011) 0.86
Effects of cations and pH on antimicrobial activity of thanatin and s-thanatin against Escherichia coli ATCC25922 and B. subtilis ATCC 21332. Curr Microbiol (2008) 0.84
Mechanisms mediating bactericidal properties and conditions that enhance the potency of a broad-spectrum oligo-acyl-lysyl. Antimicrob Agents Chemother (2010) 0.83
Bioactive dehydrotyrosyl and dehydrodopyl compounds of marine origin. Mar Drugs (2010) 0.83
Anti-microbial, anti-biofilm activities and cell selectivity of the NRC-16 peptide derived from witch flounder, Glyptocephalus cynoglossus. Mar Drugs (2013) 0.81
Subversion of interleukin-1-mediated host defence by a nasal carrier strain of Staphylococcus aureus. Immunology (2008) 0.80
Structure of chemokine-derived antimicrobial Peptide interleukin-8alpha and interaction with detergent micelles and oriented lipid bilayers. Biochemistry (2009) 0.79
Biochemical enhancement of transdermal delivery with magainin peptide: modification of electrostatic interactions by changing pH. Int J Pharm (2008) 0.79
Experimental conditions that enhance potency of an antibacterial oligo-acyl-lysyl. Antimicrob Agents Chemother (2010) 0.79
Clavanin A improves outcome of complications from different bacterial infections. Antimicrob Agents Chemother (2014) 0.79
pH Dependence of microbe sterilization by cationic antimicrobial peptides. Antimicrob Agents Chemother (2013) 0.79
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. Sci Rep (2016) 0.78
Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA. PLoS One (2015) 0.77
Structure and Bioactivity of a Modified Peptide Derived from the LPS-Binding Domain of an Anti-Lipopolysaccharide Factor (ALF) of Shrimp. Mar Drugs (2016) 0.77
Electronic detection of bacteria using holey reduced graphene oxide. ACS Appl Mater Interfaces (2014) 0.77
N-terminus three residues deletion mutant of human beta-defensin 3 with remarkably enhanced salt-resistance. PLoS One (2015) 0.77
Ultrashort Antimicrobial Peptides with Antiendotoxin Properties. Antimicrob Agents Chemother (2015) 0.77
The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss. Antimicrob Agents Chemother (2016) 0.76
Rapid Screening of Antimicrobial Synthetic Peptides. Int J Pept Res Ther (2015) 0.75
Efficacy of Antibacterial Peptides Against Peptide-Resistant MRSA Is Restored by Permeabilization of Bacteria Membranes. Front Microbiol (2016) 0.75
pH Dependent Antimicrobial Peptides and Proteins, Their Mechanisms of Action and Potential as Therapeutic Agents. Pharmaceuticals (Basel) (2016) 0.75
Destabilization of α-Helical Structure in Solution Improves Bactericidal Activity of Antimicrobial Peptides: Opposite Effects on Bacterial and Viral Targets. Antimicrob Agents Chemother (2016) 0.75
Repurposing tromethamine as inhaled therapy to treat CF airway disease. JCI Insight (2016) 0.75
Marine Antimicrobial Peptides: Nature Provides Templates for the Design of Novel Compounds against Pathogenic Bacteria. Int J Mol Sci (2016) 0.75
Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A (1987) 8.53
Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell (1996) 6.84
Peptide antibiotics and their role in innate immunity. Annu Rev Immunol (1995) 6.81
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest (1989) 5.21
Ultrasensitive assays for endogenous antimicrobial polypeptides. J Immunol Methods (1991) 4.64
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett (1993) 3.30
Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett (1995) 3.21
Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem (1982) 3.17
Plant defensins: novel antimicrobial peptides as components of the host defense system. Plant Physiol (1995) 3.03
Structure-activity studies on magainins and other host defense peptides. Biopolymers (1995) 2.80
Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. J Biol Chem (1988) 2.79
Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci U S A (1989) 2.59
Defensins. Curr Opin Immunol (1994) 2.55
Concurrent assessment of inner and outer membrane permeabilization and bacteriolysis in E. coli by multiple-wavelength spectrophotometry. J Immunol Methods (1988) 2.31
Antimicrobial activity of synthetic magainin peptides and several analogues. Proc Natl Acad Sci U S A (1988) 2.24
Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers. Biophys J (1989) 1.95
Orientational and aggregational states of magainin 2 in phospholipid bilayers. Biochemistry (1994) 1.94
Anticandidal activity of major human salivary histatins. Infect Immun (1991) 1.79
Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry (1995) 1.77
Growth-inhibitory and bactericidal effects of human parotid salivary histidine-rich polypeptides on Streptococcus mutans. Infect Immun (1984) 1.60
Magainin 1-induced leakage of entrapped calcein out of negatively-charged lipid vesicles. Biochim Biophys Acta (1989) 1.46
Synthetic bactericidal peptide based on CAP37: a 37-kDa human neutrophil granule-associated cationic antimicrobial protein chemotactic for monocytes. Proc Natl Acad Sci U S A (1993) 1.45
The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. EMBO J (1995) 1.43
Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones. Biochem J (1987) 1.38
The final pH of bacteria comprising the predominant flora on sound and carious human root and enamel surfaces. J Dent Res (1996) 1.30
Conformation of magainin-2 and related peptides in aqueous solution and membrane environments probed by Fourier transform infrared spectroscopy. Biochemistry (1992) 1.27
cDNA sequences of three sheep myeloid cathelicidins. FEBS Lett (1995) 1.20
Isolation of milligram quantities of a group of histidine-rich polypeptides from human parotid saliva. Infect Immun (1984) 1.20
Kinetics of pore formation by an antimicrobial peptide, magainin 2, in phospholipid bilayers. Biochemistry (1995) 1.20
Membrane-induced helical conformation of an active candidacidal fragment of salivary histatins. J Biol Chem (1994) 1.02
Polyacrylamide gel electrophoresis of human salivary histidine-rich-polypeptides. J Dent Res (1977) 0.99
Salivary proteolysis of histidine-rich polypeptides and the antifungal activity of peptide degradation products. Arch Oral Biol (1993) 0.99
The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide. J Biol Chem (1988) 0.93
Stabilization of helix by side-chain interactions in histatin-derived peptides: role in candidacidal activity. Biochem Biophys Res Commun (1996) 0.91
Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2). Biochem Biophys Res Commun (1989) 0.89
Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs. Am J Hum Genet (1989) 0.88
Properties of salivary basic proteins showing polymorphism. Biochem Genet (1973) 0.87
Role of hemocyte-derived granular components in invertebrate defense. Ann N Y Acad Sci (1994) 0.86
Recombinant histatins: functional domain duplication enhances candidacidal activity. Gene (1995) 0.86
Antichlamydial activity of vaginal secretion. Am J Obstet Gynecol (1995) 0.84
The intracellular pH of tunicate blood cells: Ascidia ceratodes whole blood, morula cells, vacuoles and cytoplasm. Biochim Biophys Acta (1990) 0.80
Interaction of Candida albicans with human leukocytes and serum. J Bacteriol (1969) 9.19
Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest (1985) 8.63
Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection. J Clin Invest (1969) 7.61
Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun (1984) 5.30
Severe candidal infections: clinical perspective, immune defense mechanisms, and current concepts of therapy. Ann Intern Med (1978) 4.15
Phagocytosis by human monocytes. Blood (1968) 3.96
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc Natl Acad Sci U S A (1990) 3.90
Primary structures of three human neutrophil defensins. J Clin Invest (1985) 3.70
Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem (1985) 3.58
Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils. Antimicrob Agents Chemother (1998) 3.45
Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett (1996) 3.39
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett (1993) 3.30
Immigration and the health of Asian and Pacific Islander adults in the United States. Am J Epidemiol (2001) 3.28
Antifungal effects of peroxidase systems. J Bacteriol (1969) 3.24
Microbicidal cationic proteins in rabbit alveolar macrophages: a potential host defense mechanism. Infect Immun (1980) 3.13
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proc Natl Acad Sci U S A (1998) 3.02
Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J Biol Chem (1983) 3.00
Direct inactivation of viruses by human granulocyte defensins. J Virol (1986) 3.00
Defensins. Eur J Haematol (1990) 2.88
Nonoxidative fungicidal mechanisms of mammalian granulocytes: demonstration of components with candidacidal activity in human, rabbit, and guinea pig leukocytes. Infect Immun (1975) 2.68
NADPH oxidase deficiency in X-linked chronic granulomatous disease. J Clin Invest (1975) 2.62
Defensins. Curr Opin Immunol (1994) 2.55
The gain of three mitochondrial introns identifies liverworts as the earliest land plants. Nature (1998) 2.54
Defensins. Pharmacol Ther (1995) 2.52
Risk factors for graft survival after liver transplantation from donation after cardiac death donors: an analysis of OPTN/UNOS data. Am J Transplant (2006) 2.47
Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys J (2000) 2.41
Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immun (1992) 2.39
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii. Nat Struct Biol (1998) 2.37
Cyclic 3',5'-adenosine monophosphate in the human lukocyte: synthesis, degradation, andeffects n neutrophil candidacidal activity. J Clin Invest (1971) 2.35
Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages. Infect Immun (1983) 2.33
Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes. J Virol (1985) 2.31
Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens. J Exp Med (2001) 2.28
The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms. J Clin Invest (1975) 2.26
Functional aspects of a second mechanism of candidacidal activity by human neutrophils. J Clin Invest (1972) 2.25
Defensins and other endogenous peptide antibiotics of vertebrates. J Leukoc Biol (1995) 2.25
Bactericidal activity of mammalian cathelicidin-derived peptides. Infect Immun (2000) 2.24
Susceptibility of Chlamydia trachomatis to protegrins and defensins. Infect Immun (1996) 2.16
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
Dynamic evolution of plant mitochondrial genomes: mobile genes and introns and highly variable mutation rates. Proc Natl Acad Sci U S A (2000) 2.13
Assessment of chlorination by human neutrophils. Nature (1983) 2.12
Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. Br J Cancer (2006) 2.09
Activity of rabbit leukocyte peptides against Candida albicans. Infect Immun (1985) 2.05
Development of amphotericin B-resistant Candida tropicalis in a patient with defective leukocyte function. Am J Med Sci (1979) 2.02
Mouse neutrophils lack defensins. Infect Immun (1992) 2.01
In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood (1986) 2.01
Antimicrobial peptides of vertebrates. Curr Opin Immunol (1998) 1.94
Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J (2001) 1.93
Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity. Infect Immun (1985) 1.89
Neutrophil defensins: purification, characterization, and antimicrobial testing. Methods Enzymol (1994) 1.88
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes. Chem Biol (1996) 1.87
In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J Infect Dis (1986) 1.84
Designer assays for antimicrobial peptides. Disputing the "one-size-fits-all" theory. Methods Mol Biol (1997) 1.79
Fungicidal activity of rabbit alveolar and peritoneal macrophages against Candida albicans. Infect Immun (1980) 1.79
Rubidium release: a rapid and sensitive assay for amphotericin B. J Infect Dis (1976) 1.76
Bactericidal properties of murine intestinal phospholipase A2. J Clin Invest (1995) 1.75
Phagolysosomal pH of human neutrophils. Blood (1984) 1.75
Unusual magnetic order in the pseudogap region of the superconductor HgBa2CuO4+delta. Nature (2008) 1.71
Susceptibility of Neisseria gonorrhoeae to protegrins. Infect Immun (1996) 1.65
Membrane thinning effect of the beta-sheet antimicrobial protegrin. Biochemistry (2000) 1.64
Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J Immunol (1988) 1.64
Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat Struct Biol (1999) 1.63
Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency. J Clin Invest (1988) 1.63
Microbicidal cationic proteins of rabbit alveolar macrophages: amino acid composition and functional attributes. Infect Immun (1981) 1.61
Fungicidal properties of a chymotrypsin-like cationic protein from human neutrophils: adsorption to Candida parapsilosis. Infect Immun (1977) 1.61
Isolation and characterization of human defensin cDNA clones. Proc Natl Acad Sci U S A (1988) 1.61
Defensin-rich dense granules of human neutrophils. Blood (1987) 1.59
Arginine-rich cationic proteins of human eosinophil granules: comparison of the constituents of eosinophilic and neutrophilic leukocytes. Lab Invest (1977) 1.57
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E. J Biochem (1998) 1.53
Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology (1994) 1.53
Increased content of microbicidal cationic peptides in rabbit alveolar macrophages elicited by complete Freund adjuvant. Infect Immun (1981) 1.52
Antimicrobial proteins of murine macrophages. Infect Immun (1993) 1.50
Antimicrobial activity of phagocyte granule proteins. Semin Respir Infect (1986) 1.49
Tests of consequence monotonicity in decision making under uncertainty. J Exp Psychol Learn Mem Cogn (1997) 1.47
Purification and antimicrobial properties of three defensins from rat neutrophils. Infect Immun (1989) 1.46
Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations. Eur J Biochem (1996) 1.45
The progression of retinopathy of prematurity and fluctuation in blood gas tension. Graefes Arch Clin Exp Ophthalmol (1993) 1.44
Antibiotic peptides from higher eukaryotes: biology and applications. Mol Med Today (1999) 1.44
D-amino acid oxidase in leukocytes: a possible D-amino-acid-linked antimicrobial system. Proc Natl Acad Sci U S A (1969) 1.43
Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. Am J Clin Nutr (2000) 1.43
Phagocytosis by human eosinophils. Blood (1968) 1.42
Myeloperoxidase deficiency. Immunologic study of a genetic leukocyte defect. N Engl J Med (1970) 1.41
Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report. Ann N Y Acad Sci (2000) 1.41
Effects of colchicine and chloramphenicol on the oxidative metabolism and phagocytic activity of human neutrophils. J Infect Dis (1973) 1.40
UCLA Conference. Monocytes and macrophages: functions and diseases. Ann Intern Med (1978) 1.38
In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis. Infect Immun (1996) 1.37
In vitro candidastatic properties of the human neutrophil calprotectin complex. J Immunol (1993) 1.37
Multiple states of beta-sheet peptide protegrin in lipid bilayers. Biochemistry (1998) 1.36
Membrane channel formation by antimicrobial protegrins. Biochim Biophys Acta (1999) 1.36
Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli. J Clin Invest (1994) 1.34
Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes. FEBS Lett (1994) 1.33
Antimicrobial peptides of leukocytes. Curr Opin Hematol (1997) 1.32
Activity of defensins from human neutrophilic granulocytes against Mycobacterium avium-Mycobacterium intracellulare. Infect Immun (1992) 1.32
Secretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears. Infect Immun (1998) 1.31
Inhibition by sulfonamides of the candidacidal activity of human neutrophils. J Clin Invest (1971) 1.30
Defective bactericidal activity in myeloperoxidase-deficient human neutrophils. Nature (1969) 1.29
The structure of the sinus wall of the lymph node relative to its endocytic properties and transmural cell passage. Am J Anat (1980) 1.29
Human neutrophil antimicrobial activity. Rev Infect Dis (1988) 1.28