The zebrafish: heritable disorders in transparent embryos.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 507246)

Published in J Clin Invest on April 15, 1996

Authors

W Driever1, M C Fishman

Author Affiliations

1: Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachuetts 02129, USA.

Articles cited by this

Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72

Mutations affecting segment number and polarity in Drosophila. Nature (1980) 18.72

Hox genes in vertebrate development. Cell (1994) 9.27

Production of clones of homozygous diploid zebra fish (Brachydanio rerio). Nature (1981) 6.23

Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Curr Biol (1994) 4.05

Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med (1995) 3.59

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature (1995) 3.39

A genetic linkage map for the zebrafish. Science (1994) 3.31

Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation. Cell (1993) 3.25

Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics (1994) 3.24

no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development (1994) 3.14

Temperature-sensitive developmental mutants of Caenorhabditis elegans. Dev Biol (1976) 2.83

A behavioral screen for isolating zebrafish mutants with visual system defects. Proc Natl Acad Sci U S A (1995) 2.66

Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development (1988) 2.28

A homeobox gene essential for zebrafish notochord development. Nature (1995) 2.25

Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish. Science (1994) 2.16

Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell (1993) 2.12

Zebrafish: genetic tools for studying vertebrate development. Trends Genet (1994) 1.85

Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formation. Development (1993) 1.85

Control of dorsoventral patterning of somitic derivatives by notochord and floor plate. Proc Natl Acad Sci U S A (1993) 1.51

Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus. Proc Natl Acad Sci U S A (1988) 1.46

The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature (1991) 1.39

Patterning the zebrafish heart tube: acquisition of anteroposterior polarity. Dev Biol (1992) 1.24

Specific activation of mammalian Hox promoters in mosaic transgenic zebrafish. Genes Dev (1992) 1.21

Of fin and fur: mutational analysis of vertebrate embryonic development. Genes Dev (1992) 1.20

Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart field. Development (1994) 1.12

Of flies and fishes. Science (1994) 1.10

lacZ expression in germline transgenic zebrafish can be detected in living embryos. Dev Biol (1994) 0.91

Control of vertebrate gastrulation: inducing signals and responding genes. Curr Opin Genet Dev (1993) 0.90

Patterning of body segments of the zebrafish embryo. Curr Top Dev Biol (1991) 0.89

Development of motoneuronal phenotype. Annu Rev Neurosci (1994) 0.82

Pattern formation in the vertebrate neural plate. Trends Neurosci (1994) 0.81

Articles by these authors

(truncated to the top 100)

Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature (1995) 9.86

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest (1998) 5.95

Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science (1994) 5.15

Targeted disruption of the neuronal nitric oxide synthase gene. Cell (1993) 5.02

Prevention of vertebrate neuronal death by the crmA gene. Science (1994) 4.09

Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (1996) 3.63

Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med (1995) 3.59

Zebrafish genetic map with 2000 microsatellite markers. Genomics (1999) 3.56

Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science (1996) 3.32

Gridlock signalling pathway fashions the first embryonic artery. Nature (2001) 3.30

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature (1995) 3.15

Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (1998) 3.07

A microsatellite genetic linkage map for zebrafish (Danio rerio). Nat Genet (1998) 3.06

Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development (1995) 3.05

Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature (1996) 2.94

gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science (2000) 2.90

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab (1996) 2.78

Potassium current suppression by quinidine reveals additional calcium currents in neuroblastoma cells. Proc Natl Acad Sci U S A (1981) 2.45

Hematopoietic mutations in the zebrafish. Development (1996) 2.25

Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (1996) 2.12

Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J Cereb Blood Flow Metab (1996) 2.01

Vessel patterning in the embryo of the zebrafish: guidance by notochord. Dev Biol (1997) 1.99

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med (1997) 1.89

Cardiovascular development in the zebrafish. I. Myocardial fate map and heart tube formation. Development (1993) 1.85

Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (1997) 1.84

G0 is a major growth cone protein subject to regulation by GAP-43. Nature (1990) 1.72

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell (1995) 1.71

A reference cross DNA panel for zebrafish (Danio rerio) anchored with simple sequence length polymorphisms. Development (1996) 1.67

Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice. J Clin Invest (1998) 1.65

Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit. Dev Cell (2001) 1.65

Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ Res (1997) 1.63

Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell (1996) 1.61

Mutations affecting development of zebrafish digestive organs. Development (1996) 1.58

Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Science (1987) 1.57

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science (1994) 1.56

Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice. Br J Pharmacol (1999) 1.54

Partitioning of tissue expression accompanies multiple duplications of the Na+/K+ ATPase alpha subunit gene. Genome Res (2001) 1.50

A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43. Nature (1989) 1.49

G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. Proc Natl Acad Sci U S A (1997) 1.48

Pre-pattern in the pronephric kidney field of zebrafish. Development (2001) 1.43

Neuronal traits of clonal cell lines derived by fusion of dorsal root ganglia neurons with neuroblastoma cells. Proc Natl Acad Sci U S A (1985) 1.36

Neuronal constitutive nitric oxide synthase is involved in murine enteric inhibitory neurotransmission. J Clin Invest (1996) 1.35

Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate. Proc Natl Acad Sci U S A (1997) 1.30

Regulation in the heart field of zebrafish. Development (1998) 1.29

A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nat Genet (1994) 1.28

A long purine-pyrimidine homopolymer acts as a transcriptional diode. J Biol Chem (1995) 1.27

Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr Biol (2001) 1.27

ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. Am J Physiol (1996) 1.26

Modulation of mouse cardiac function in vivo by eNOS and ANP. Am J Physiol Heart Circ Physiol (2000) 1.25

Patterning the zebrafish heart tube: acquisition of anteroposterior polarity. Dev Biol (1992) 1.24

Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A (1998) 1.23

Genetics of heart development. Trends Genet (2000) 1.23

Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts. Proc Natl Acad Sci U S A (2005) 1.21

Endogenous digitalis-like activity in mammalian brain. Proc Natl Acad Sci U S A (1979) 1.21

The neuronal growth-associated protein GAP-43 induces filopodia in non-neuronal cells. Science (1989) 1.19

Oxygen chemoreception by carotid body cells in culture. Proc Natl Acad Sci U S A (1985) 1.17

Neuronal cell surface molecules mediate specific binding to rabies virus glycoprotein expressed by a recombinant baculovirus on the surfaces of lepidopteran cells. J Virol (1998) 1.14

Neurochemical characteristics of a novel dorsal root ganglion X neuroblastoma hybrid cell line, F-11. J Neurochem (1987) 1.14

The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish. Am J Physiol Heart Circ Physiol (2001) 1.14

Palmitoylation alters protein activity: blockade of G(o) stimulation by GAP-43. EMBO J (1992) 1.13

Cardiovascular development in the zebrafish. II. Endocardial progenitors are sequestered within the heart field. Development (1994) 1.12

Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria. Curr Biol (2000) 1.09

Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Dev Biol (2001) 1.08

Cyclooxygenase-2 mediates increased renal renin content induced by low-sodium diet. Hypertension (1997) 1.07

Regional cerebral blood flow response to vibrissal stimulation in mice lacking type I NOS gene expression. Am J Physiol (1996) 1.07

Sir Henry Hallett Dale and acetylcholine story. Yale J Biol Med (1972) 1.07

Structure and expression of murine intestinal trefoil factor: high evolutionary conservation and postnatal expression. Biochem Biophys Res Commun (1995) 1.06

"Physiological genomics": mutant screens in zebrafish. Am J Physiol (1998) 1.06

Zebrafish genetics: the enigma of arrival. Proc Natl Acad Sci U S A (1999) 1.05

Nitric oxide inhibits alpha2-adrenoceptor-mediated endothelium-dependent vasodilation. Circ Res (1998) 1.05

The genetic basis of cardiac function: dissection by zebrafish (Danio rerio) screens. Philos Trans R Soc Lond B Biol Sci (2000) 1.05

GAP-43 as a plasticity protein in neuronal form and repair. J Neurobiol (1992) 1.04

Integration of auditory information in the cat's visual cortex. Vision Res (1973) 1.04

Mediation by G proteins of signals that cause collapse of growth cones. Science (1993) 1.04

Cloning of human GAP-43: growth association and ischemic resurgence. Neuron (1988) 1.02

GAP-43 transgenic mice: dispersed genomic sequences confer a GAP-43-like expression pattern during development and regeneration. J Neurosci (1994) 1.01

Nuclear magnetic resonance imaging in evaluation and follow-up of children treated for coarctation of the aorta. J Am Coll Cardiol (1986) 1.01

Activated mutants of the alpha subunit of G(o) promote an increased number of neurites per cell. J Neurosci (1994) 0.99

Genetic steps to organ laterality in zebrafish. Comp Funct Genomics (2001) 0.98

Notochord regulates cardiac lineage in zebrafish embryos. Dev Biol (1998) 0.98

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids. J Biol Chem (1988) 0.96

Three zebrafish MEF2 genes delineate somitic and cardiac muscle development in wild-type and mutant embryos. Mech Dev (1996) 0.96

GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1993) 0.96

Estrogen mediates the protective effects of pregnancy and chorionic gonadotropin in a mouse model of vascular injury. Arterioscler Thromb Vasc Biol (1999) 0.95

The RNA subunit of ribonuclease P from the zebrafish, Danio rerio. J Biol Chem (1996) 0.95

GAP-43 gene expression during development: persistence in a distinctive set of neurons in the mature central nervous system. Brain Res Dev Brain Res (1989) 0.95

Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression. Stroke (1996) 0.94

The zebrafish as a model system to study cardiovascular development. Trends Cardiovasc Med (2011) 0.94

An intracellular guanine nucleotide release protein for G0. GAP-43 stimulates isolated alpha subunits by a novel mechanism. J Biol Chem (1991) 0.93

Membrane potential of juxtaglomerular cells. Nature (1976) 0.92

Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. Proc Natl Acad Sci U S A (1995) 0.91

Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase. Neuroscience (1996) 0.91

Increased susceptibility to development of triggered activity in myocytes from mice with targeted disruption of endothelial nitric oxide synthase. J Mol Cell Cardiol (2000) 0.91

Cardiovascular morphogenesis in zebrafish. Cardiovasc Res (1996) 0.90

GAP-43 amino terminal peptides modulate growth cone morphology and neurite outgrowth. J Neurosci (1994) 0.90

Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Genome Res (2000) 0.90

The dissection sign of nonreducible ileocolic intussusception. AJR Am J Roentgenol (1984) 0.90

Axonal proteins of presynaptic neurons during synaptogenesis. Science (1983) 0.89

An amino-terminal domain of the growth-associated protein GAP-43 mediates its effects on filopodial formation and cell spreading. J Cell Sci (1994) 0.89

Zebrafish YAC, BAC, and PAC genomic libraries. Methods Cell Biol (1999) 0.89