Published in Science on February 09, 1996
Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda. Microbiol Mol Biol Rev (1999) 6.92
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy. Nat Methods (2008) 6.75
Stretching DNA with optical tweezers. Biophys J (1997) 6.55
Ionic effects on the elasticity of single DNA molecules. Proc Natl Acad Sci U S A (1997) 6.20
Biophysical characterization of DNA binding from single molecule force measurements. Phys Life Rev (2010) 5.81
Behavior of supercoiled DNA. Biophys J (1998) 4.86
Magnetic tweezers: micromanipulation and force measurement at the molecular level. Biophys J (2002) 4.49
Estimating the persistence length of a worm-like chain molecule from force-extension measurements. Biophys J (1999) 4.42
Conformational analysis of nucleic acids revisited: Curves+. Nucleic Acids Res (2009) 3.76
Dynamic force spectroscopy of single DNA molecules. Proc Natl Acad Sci U S A (1999) 3.50
Mechanical stability of single DNA molecules. Biophys J (2000) 3.40
Replication by a single DNA polymerase of a stretched single-stranded DNA. Proc Natl Acad Sci U S A (2000) 3.29
Mechanical separation of the complementary strands of DNA. Proc Natl Acad Sci U S A (1997) 3.25
Force-induced melting of the DNA double helix 1. Thermodynamic analysis. Biophys J (2001) 3.03
Single-molecule imaging of RNA polymerase-DNA interactions in real time. Biophys J (1999) 3.03
Forces generated during actin-based propulsion: a direct measurement by micromanipulation. Proc Natl Acad Sci U S A (2004) 2.73
Modelling extreme stretching of DNA. Nucleic Acids Res (1996) 2.69
Salt dependence of the elasticity and overstretching transition of single DNA molecules. Biophys J (2002) 2.39
Torsional directed walks, entropic elasticity, and DNA twist stiffness. Proc Natl Acad Sci U S A (1997) 2.36
Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A (1998) 2.35
Effect of pH on the overstretching transition of double-stranded DNA: evidence of force-induced DNA melting. Biophys J (2001) 2.29
Unzipping DNA with optical tweezers: high sequence sensitivity and force flips. Biophys J (2002) 2.26
Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases. Proc Natl Acad Sci U S A (2003) 2.15
DNA basepair step deformability inferred from molecular dynamics simulations. Biophys J (2003) 2.12
Single-molecule biophysics: at the interface of biology, physics and chemistry. J R Soc Interface (2008) 2.06
RecA binding to a single double-stranded DNA molecule: a possible role of DNA conformational fluctuations. Proc Natl Acad Sci U S A (1998) 2.00
Entropy and heat capacity of DNA melting from temperature dependence of single molecule stretching. Biophys J (2001) 1.99
Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging. Proc Natl Acad Sci U S A (2009) 1.95
Extension of torsionally stressed DNA by external force. Biophys J (1997) 1.83
Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophys J (2004) 1.74
Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching. Proc Natl Acad Sci U S A (2001) 1.69
Discovery through the computational microscope. Structure (2009) 1.67
DNA curvature and flexibility in vitro and in vivo. Q Rev Biophys (2010) 1.63
pH-dependent specific binding and combing of DNA. Biophys J (1997) 1.60
Stretching single-stranded DNA: interplay of electrostatic, base-pairing, and base-pair stacking interactions. Biophys J (2001) 1.58
Polymer models of meiotic and mitotic chromosomes. Mol Biol Cell (1997) 1.57
A two-state kinetic model for the unfolding of single molecules by mechanical force. Proc Natl Acad Sci U S A (2002) 1.57
Single-molecule analysis of 1D diffusion and transcription elongation of T7 RNA polymerase along individual stretched DNA molecules. Nucleic Acids Res (2007) 1.54
The relative flexibility of B-DNA and A-RNA duplexes: database analysis. Nucleic Acids Res (2004) 1.52
Driving proteins off DNA using applied tension. Biophys J (1997) 1.51
Local DNA stretching mimics the distortion caused by the TATA box-binding protein. Proc Natl Acad Sci U S A (1997) 1.47
Single-particle tracking for DNA tether length monitoring. Nucleic Acids Res (2004) 1.46
DNA overstretching in the presence of glyoxal: structural evidence of force-induced DNA melting. Biophys J (2008) 1.45
Elasticity theory of the B-DNA to S-DNA transition. Biophys J (1998) 1.44
Trapping and wiggling: elastohydrodynamics of driven microfilaments. Biophys J (1998) 1.44
Unraveling proteins: a molecular mechanics study. Biophys J (1999) 1.43
Beyond gel electrophoresis: microfluidic separations, fluorescence burst analysis, and DNA stretching. Chem Rev (2012) 1.42
An integrated laser trap/flow control video microscope for the study of single biomolecules. Biophys J (2000) 1.42
Dual binding modes for an HMG domain from human HMGB2 on DNA. Biophys J (2005) 1.41
Two distinct overstretched DNA states. Nucleic Acids Res (2010) 1.39
Single-molecule detection of DNA hybridization. Proc Natl Acad Sci U S A (2003) 1.39
Polymer chain models of DNA and chromatin. Eur Phys J E Soft Matter (2006) 1.38
Thermodynamic and kinetic aspects of RNA pulling experiments. Biophys J (2005) 1.38
Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching. Nucleic Acids Res (2010) 1.35
Quantitative study of polymer conformation and dynamics by single-particle tracking. Biophys J (1999) 1.34
DNA folding: structural and mechanical properties of the two-angle model for chromatin. Biophys J (2001) 1.34
Single chromatin fiber stretching reveals physically distinct populations of disassembly events. Biophys J (2005) 1.33
Fast-scan atomic force microscopy reveals that the type III restriction enzyme EcoP15I is capable of DNA translocation and looping. Proc Natl Acad Sci U S A (2007) 1.31
Observation by fluorescence microscopy of transcription on single combed DNA. Proc Natl Acad Sci U S A (2002) 1.30
Kinetics and mechanism of DNA uptake into the cell nucleus. Proc Natl Acad Sci U S A (2001) 1.29
Conformational Analysis of Stiff Chiral Polymers with End-Constraints. Mol Simul (2006) 1.27
The structure of DNA overstretched from the 5'5' ends differs from the structure of DNA overstretched from the 3'3' ends. Proc Natl Acad Sci U S A (2009) 1.26
Relating single-molecule measurements to thermodynamics. Biophys J (2003) 1.26
An extended DNA structure through deoxyribose-base stacking induced by RecA protein. Proc Natl Acad Sci U S A (1997) 1.26
Probing complex RNA structures by mechanical force. Eur Phys J E Soft Matter (2003) 1.22
Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements. Proc Natl Acad Sci U S A (2012) 1.17
There and (slowly) back again: entropy-driven hysteresis in a model of DNA overstretching. Biophys J (2007) 1.17
Braiding DNA: experiments, simulations, and models. Biophys J (2005) 1.16
Group theory and biomolecular conformation: I. Mathematical and computational models. J Phys Condens Matter (2010) 1.15
An effective mesoscopic model of double-stranded DNA. J Biol Phys (2013) 1.14
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopy. Proc Natl Acad Sci U S A (2013) 1.14
Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry. Proc Natl Acad Sci U S A (2013) 1.14
DNA mechanics as a tool to probe helicase and translocase activity. Nucleic Acids Res (2006) 1.13
Tension induces a base-paired overstretched DNA conformation. Proc Natl Acad Sci U S A (2012) 1.13
DnaB helicase activity is modulated by DNA geometry and force. Biophys J (2010) 1.12
B-S transition in short oligonucleotides. Biophys J (2007) 1.11
Dicentric chromosome stretching during anaphase reveals roles of Sir2/Ku in chromatin compaction in budding yeast. Mol Biol Cell (2001) 1.10
Disruption of protein-mediated DNA looping by tension in the substrate DNA. Biophys J (2005) 1.09
Interaction of oxazole yellow dyes with DNA studied with hybrid optical tweezers and fluorescence microscopy. Biophys J (2009) 1.08
Force spectroscopy with a small dithering of AFM tip: a method of direct and continuous measurement of the spring constant of single molecules and molecular complexes. Biophys J (2004) 1.05
Structure and energy of a DNA dodecamer under tensile load. Nucleic Acids Res (2005) 1.04
Torsional sensing of small-molecule binding using magnetic tweezers. Nucleic Acids Res (2010) 1.03
Routine and timely sub-picoNewton force stability and precision for biological applications of atomic force microscopy. Nano Lett (2012) 1.03
Chromatin fiber dynamics under tension and torsion. Int J Mol Sci (2010) 1.03
DNA-protein cooperative binding through variable-range elastic coupling. Biophys J (1999) 1.03
Forces on chromosomal DNA during anaphase. Biophys J (1996) 1.03
From atomic to mesoscopic descriptions of the internal dynamics of DNA. Biophys J (1999) 1.01
A molecular model for RecA-promoted strand exchange via parallel triple-stranded helices. Biophys J (1999) 1.01
Twisting and untwisting a single DNA molecule covered by RecA protein. Biophys J (2004) 1.00
Identification of binding mechanisms in single molecule-DNA complexes. Biophys J (2003) 0.98
Nonlinear mechanics of soft fibrous networks. J R Soc Interface (2007) 0.98
Optical tweezers experiments resolve distinct modes of DNA-protein binding. Biopolymers (2009) 0.97
Evaluation of elastic properties of atomistic DNA models. Biophys J (2006) 0.96
Probing protein mechanics: residue-level properties and their use in defining domains. Biophys J (2004) 0.96
Force measurements on single molecular contacts through evanescent wave microscopy. Biophys J (2001) 0.96
Reaction path ensemble of the B-Z-DNA transition: a comprehensive atomistic study. Nucleic Acids Res (2012) 0.95
Predicting the rupture probabilities of molecular bonds in series. Biophys J (2007) 0.95
On structural transitions, thermodynamic equilibrium, and the phase diagram of DNA and RNA duplexes under torque and tension. Proc Natl Acad Sci U S A (2006) 0.95
Inferring the diameter of a biopolymer from its stretching response. Biophys J (2005) 0.94
Single-molecule studies of the stringency factors and rates governing the polymerization of RecA on double-stranded DNA. Nucleic Acids Res (2011) 0.94
Conformational and helicoidal analysis of 30 PS of molecular dynamics on the d(CGCGAATTCGCG) double helix: "curves", dials and windows. J Biomol Struct Dyn (1989) 3.78
Energetic coupling between DNA bending and base pair opening. Proc Natl Acad Sci U S A (1988) 2.84
A new approach to the rapid determination of protein side chain conformations. J Biomol Struct Dyn (1991) 2.79
Modelling extreme stretching of DNA. Nucleic Acids Res (1996) 2.69
Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A (1998) 2.35
Description of six new capsular types (29-34) of Streptococcus suis. J Vet Diagn Invest (1995) 2.16
Does Paramecium primaurelia use a different genetic code in its macronucleus? Nature (1985) 2.04
RecA binding to a single double-stranded DNA molecule: a possible role of DNA conformational fluctuations. Proc Natl Acad Sci U S A (1998) 2.00
Activity of sulbactam in combination with ceftriaxone in vitro and in experimental endocarditis caused by Escherichia coli producing SHV-2-like beta-lactamase. Antimicrob Agents Chemother (1990) 1.96
Elasticity and structure of eukaryote chromosomes studied by micromanipulation and micropipette aspiration. J Cell Biol (1997) 1.94
Characterization of a histone-like protein extracted from yeast mitochondria. Proc Natl Acad Sci U S A (1979) 1.93
Challenges of cardiovascular risk assessment in the routine rheumatology outpatient setting: an observational study of 110 rheumatoid arthritis patients. Arthritis Care Res (Hoboken) (2013) 1.76
Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071. Nucleic Acids Res (1983) 1.73
Aspirin versus low-dose low-molecular-weight heparin: antithrombotic therapy in pediatric ischemic stroke patients: a prospective follow-up study. Stroke (2001) 1.71
Ultrafast random-access scanning in two-photon microscopy using acousto-optic deflectors. J Neurosci Methods (2006) 1.70
Describing protein structure: a general algorithm yielding complete helicoidal parameters and a unique overall axis. Proteins (1989) 1.70
Nucleotide sequence of the Paramecium primaurelia G surface protein. A huge protein with a highly periodic structure. J Mol Biol (1986) 1.65
Production of virulence-related proteins by Canadian strains of Streptococcus suis capsular type 2. Can J Vet Res (1998) 1.63
BI-BII transitions in B-DNA. Nucleic Acids Res (1993) 1.56
Exchange of histone H1 between segments of chromatin. J Mol Biol (1981) 1.51
Local DNA stretching mimics the distortion caused by the TATA box-binding protein. Proc Natl Acad Sci U S A (1997) 1.47
Telomeric site position heterogeneity in macronuclear DNA of Paramecium primaurelia. Nucleic Acids Res (1987) 1.45
Unraveling proteins: a molecular mechanics study. Biophys J (1999) 1.43
Fast kinetics of chromatin assembly revealed by single-molecule videomicroscopy and scanning force microscopy. Proc Natl Acad Sci U S A (2000) 1.40
Measuring the geometry of DNA grooves. Biopolymers (1994) 1.40
ELECTRON MAGNETIC RESONANCE OF CH(COOH)(2). Proc Natl Acad Sci U S A (1959) 1.38
Dynamics of a tethered polymer in shear flow. Phys Rev Lett (2000) 1.38
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Reversible and irreversible unfolding of mitotic newt chromosomes by applied force. Mol Biol Cell (2000) 1.31
Minor head injury as cause and co-factor in the aetiology of stroke in childhood: a report of eight cases. J Neurol Neurosurg Psychiatry (2002) 1.31
Kinetics and mechanism of DNA uptake into the cell nucleus. Proc Natl Acad Sci U S A (2001) 1.29
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Ceftriaxone-netilmicin combination in single-daily-dose treatment of experimental Escherichia coli endocarditis. Antimicrob Agents Chemother (1989) 1.27
Repression of gene expression by cdll products in Paramecium. Genetics (1967) 1.26
Probing complex RNA structures by mechanical force. Eur Phys J E Soft Matter (2003) 1.22
Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes. Diabetologia (2008) 1.22
Segregation in DNA solutions induced by electric fields. Science (1995) 1.20
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
Hemagglutination properties of Streptococcus suis. J Clin Microbiol (1990) 1.19
Specific expression of matrix metalloproteinases 1, 3, 9 and 13 associated with invasiveness of breast cancer cells in vitro. Clin Exp Metastasis (2000) 1.19
Structural transitions in DNA driven by external force and torque. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 1.19
Conformational sub-states in B-DNA. J Mol Biol (1992) 1.15
Prospective randomized trial of thoracostomy removal algorithms. J Trauma (1999) 1.14
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
In vitro synergistic effects of double and triple combinations of beta-lactams, vancomycin, and netilmicin against methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother (2000) 1.13
The electrostatic potential and steric accessibility of reactive sites within Z-DNA. Nucleic Acids Res (1980) 1.11
Energetic and conformational aspects of A:T base-pair opening within the DNA double helix. Chemphyschem (2001) 1.10
Molecular modelling of (A4T4NN)n and (T4A4NN)n: sequence elements responsible for curvature. Nucleic Acids Res (1996) 1.10
Microrheology of biopolymer-membrane complexes. Phys Rev Lett (2000) 1.09
Individualized developmental care for very-low-birth-weight premature infants. Clin Pediatr (Phila) (1995) 1.09
Non-additivity in protein-DNA binding. Bioinformatics (2005) 1.09
DNA structural forms. Q Rev Biophys (1996) 1.08
Search for tb resonances in proton-proton collisions at √s=7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.07
Macronuclear structure of the G surface antigen gene of Paramecium primaurelia and direct expression of its repeated epitopes in Escherichia coli. Mol Cell Biol (1985) 1.06
[Sequencing of DNA by mechanical opening of the double helix: a theoretical evaluation]. C R Acad Sci III (1994) 1.06
Symptomatic ischemic stroke in full-term neonates : role of acquired and genetic prothrombotic risk factors. Stroke (2000) 1.05
Generalized tube model of biased reptation for gel electrophoresis of DNA. Science (1989) 1.05
Search for a light Higgs boson decaying to long-lived weakly interacting particles in proton-proton collisions at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.05
Magnesium sulfate in the treatment of refractory ventricular fibrillation in the prehospital setting. Resuscitation (2001) 1.04
Viscoelastic properties of actin-coated membranes. Phys Rev E Stat Nonlin Soft Matter Phys (2001) 1.03
Modelling DNA stretching for physics and biology. Genetica (1999) 1.03
A possible family of B-like triple helix structures: comparison with the Arnott A-like triple helix. Biochemistry (1993) 1.02
Fusobacterium nucleatum hepatic abscess with pylephlebitis associated with idiopathic CD4(+) T lymphocytopenia. Clin Infect Dis (2001) 1.02
Acting on actin: the electric motility assay. Eur Biophys J (1998) 1.01
From atomic to mesoscopic descriptions of the internal dynamics of DNA. Biophys J (1999) 1.01
Clonal variation in paramecium. Heterogeneity within clones of identical serotypes. Genetics (1972) 1.01
Blocking of in vitro translation of Paramecium messenger RNAs is due to messenger RNA primary structure. Biochimie (1984) 1.01
A molecular model for RecA-promoted strand exchange via parallel triple-stranded helices. Biophys J (1999) 1.01
Two aspects of DNA polymorphism and microheterogeneity: molecular electrostatic potential and steric accessibility. Eur J Biochem (1982) 1.01
Role of non-surface antigens in controlling Paramecium surface antigen synthesis. J Protozool (1969) 1.00
The electrostatic molecular potential of tRNAPhe. IV. The potentials and steric accessibilities of sites associated with the bases. Nucleic Acids Res (1980) 1.00
The electrostatic molecular potential of yeast tRNAPhe. (I). The potential due to the phosphate backbone. Nucleic Acids Res (1980) 1.00
Search for supersymmetry in events with three leptons and missing transverse momentum in √[s]=7 TeV pp collisions with the ATLAS detector. Phys Rev Lett (2012) 0.99
Ureteral trauma: preoperative studies neither predict injury nor prevent missed injuries. J Am Coll Surg (1998) 0.97
The flexibility of the nucleic acids: (I). "SIR", a novel approach to the variation of polymer geometry in constrained systems. J Biomol Struct Dyn (1986) 0.96
Familial articular chondrocalcinosis in Quebec. Arthritis Rheum (1981) 0.96
Genetics of ovarian differentiation: Rspo1, a major player. Sex Dev (2008) 0.96
A new theoretical index of biochemical reactivity combining steric and electrostatic factors. An application to yeast tRNAPhe. Biophys Chem (1984) 0.95
HLA antigens in narcolepsy and idiopathic central nervous system hypersomnolence. Sleep (1986) 0.95
The molecular electrostatic potential and steric accessibility of A-DNA. Nucleic Acids Res (1981) 0.95
DNA sequencing with direct blotting electrophoresis and colorimetric detection. Biotechniques (1989) 0.94
A computational and experimental study of the bending induced at a double-triple helix junction. Biophys Chem (1992) 0.93
ADAPT: a molecular mechanics approach for studying the structural properties of long DNA sequences. Biopolymers (2001) 0.93
Sequence-specific epigenetic effects of the maternal somatic genome on developmental rearrangements of the zygotic genome in Paramecium primaurelia. Mol Cell Biol (1997) 0.93
Solid friction and polymer relaxation in gel electrophoresis. Science (1994) 0.93
Sequence-dependent dynamics of TATA-Box binding sites. Biophys J (1998) 0.93
Optimization of nucleic acid sequences. Biophys J (2000) 0.93
[Waardenburg's syndrome and severe cyanotic cardiopathy]. Arch Fr Pediatr (1990) 0.93
Clonal variation in paramecium. II. A comparison of stable and unstable clones of the same serotype. Genetics (1972) 0.92
Clonal variation in paramecium. I. Persistent unstable clones. Genetics (1972) 0.92
Irreversible trapping of DNA during crossed-field gel electrophoresis. Electrophoresis (1992) 0.92
Studies of skin allograft survival and mixed lymphocyte culture reaction in Hl-A-genotyped families. Transplant Proc (1972) 0.91
The impact of abasic sites on DNA flexibility. J Biomol Struct Dyn (2000) 0.91
Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome. Clin Infect Dis (2001) 0.91
Sequence-targeted cleavage of nucleic acids by oligo-alpha-thymidylate-phenanthroline conjugates: parallel and antiparallel double helices are formed with DNA and RNA, respectively. Biochemistry (1988) 0.91
Conformational properties of the TATA-box binding sequence of DNA. J Biomol Struct Dyn (1997) 0.91
Theoretical prediction of base sequence effects in DNA. Experimental reactivity of Z-DNA and B-Z transition enthalpies. J Mol Biol (1989) 0.90