Published in J Biochem on December 01, 1995
Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol (2000) 5.24
Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J Physiol (2001) 1.96
Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle. J Physiol (2003) 1.86
Smooth muscle signalling pathways in health and disease. J Cell Mol Med (2008) 1.72
Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase. Biochem J (2002) 1.60
Reconstitution of protein kinase C-induced contractile Ca2+ sensitization in triton X-100-demembranated rabbit arterial smooth muscle. J Physiol (1999) 1.59
Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle. J Physiol (1998) 1.46
Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors. J Biol Chem (2009) 1.45
Agonist-induced changes in the phosphorylation of the myosin- binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle. Biochem J (2003) 1.38
Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction. J Biol Chem (2009) 1.32
Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits. Proc Natl Acad Sci U S A (2004) 1.30
Phosphorylation of the myosin phosphatase inhibitors, CPI-17 and PHI-1, by integrin-linked kinase. Biochem J (2002) 1.29
RhoA/Rho-kinase and vascular diseases: what is the link? Cell Mol Life Sci (2010) 1.24
Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca2+ and decreased cGMP-induced relaxation. Proc Natl Acad Sci U S A (2006) 1.22
The role of actin filament dynamics in the myogenic response of cerebral resistance arteries. J Cereb Blood Flow Metab (2012) 1.21
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo. Am J Physiol Cell Physiol (2008) 1.20
Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis. Br J Pharmacol (2000) 1.18
Nonmuscle myosin is regulated during smooth muscle contraction. Am J Physiol Heart Circ Physiol (2009) 1.13
Rho-kinase-mediated regulation of receptor-agonist-stimulated smooth muscle contraction. Pflugers Arch (2006) 1.06
Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor. Structure (2007) 1.02
The latch-bridge hypothesis of smooth muscle contraction. Can J Physiol Pharmacol (2005) 1.01
Maturation and the role of PKC-mediated contractility in ovine cerebral arteries. Am J Physiol Heart Circ Physiol (2009) 1.01
Reactive oxygen species are involved in regulating alpha1-adrenoceptor-activated vascular smooth muscle contraction. J Biomed Sci (2010) 0.98
Carbachol-induced rabbit bladder smooth muscle contraction: roles of protein kinase C and Rho kinase. Am J Physiol Renal Physiol (2009) 0.98
Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders. World J Gastrointest Pathophysiol (2011) 0.98
Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in beta-escin skinned rat and guinea-pig bladders. Br J Pharmacol (2006) 0.97
Chemical genetics of zipper-interacting protein kinase reveal myosin light chain as a bona fide substrate in permeabilized arterial smooth muscle. J Biol Chem (2011) 0.97
Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1). Mol Hum Reprod (2011) 0.96
A novel RhoA/ROCK-CPI-17-MEF2C signaling pathway regulates vascular smooth muscle cell gene expression. J Biol Chem (2012) 0.96
Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injury. Tissue Barriers (2015) 0.94
Involvement of Rho-kinase in contraction of guinea-pig aorta induced by prostanoid EP3 receptor agonists. Br J Pharmacol (2003) 0.93
Par-4: a new activator of myosin phosphatase. Mol Biol Cell (2010) 0.91
The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle. Biochem J (2000) 0.90
Ca2+ sensitization due to myosin light chain phosphatase inhibition and cytoskeletal reorganization in the myogenic response of skeletal muscle resistance arteries. J Physiol (2012) 0.90
GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA. Biochem J (2004) 0.87
Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders. Pharmacol Rev (2016) 0.87
Expression of CPI-17 in smooth muscle during embryonic development and in neointimal lesion formation. Histochem Cell Biol (2009) 0.86
A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center. Dev Biol (2011) 0.86
GATA-6 and NF-κB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contraction. Mol Cell Biol (2012) 0.86
Myosin phosphatase isoforms as determinants of smooth muscle contractile function and calcium sensitivity of force production. Microcirculation (2014) 0.85
17beta-estradiol attenuates vascular contraction through inhibition of RhoA/Rho kinase pathway. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.85
Phorbol 12,13-dibutyrate-induced, protein kinase C-mediated contraction of rabbit bladder smooth muscle. Front Pharmacol (2012) 0.84
Downregulation of CPI-17 contributes to dysfunctional motility in chronic intestinal inflammation model mice and ulcerative colitis patients. J Gastroenterol (2008) 0.84
Flavone Attenuates Vascular Contractions by Inhibiting RhoA/Rho Kinase Pathway. Korean J Physiol Pharmacol (2009) 0.83
PHI-1 interacts with the catalytic subunit of myosin light chain phosphatase to produce a Ca(2+) independent increase in MLC(20) phosphorylation and force in avian smooth muscle. FEBS Lett (2006) 0.83
The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure. J Cell Mol Med (2008) 0.83
Mechanical stretch upregulates proteins involved in Ca2+ sensitization in urinary bladder smooth muscle hypertrophy. Am J Physiol Cell Physiol (2014) 0.83
PKC and Rho in vascular smooth muscle: activation by BOXes and SAH CSF. Front Biosci (2008) 0.81
A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol (2011) 0.80
Inhibition of smooth-muscle myosin-light-chain phosphatase by Ruthenium Red. Biochem J (2000) 0.80
Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle. Fundam Clin Pharmacol (2009) 0.80
An integrated mathematical model of thrombin-, histamine-and VEGF-mediated signalling in endothelial permeability. BMC Syst Biol (2011) 0.80
Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem (2012) 0.80
Contractile agonists attenuate cGMP levels by stimulating phosphorylation of cGMP-specific PDE5; an effect mediated by RhoA/PKC-dependent inhibition of protein phosphatase 1. Br J Pharmacol (2008) 0.79
CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins. Oncotarget (2016) 0.79
Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension. PLoS One (2015) 0.78
Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundus. PLoS One (2013) 0.78
Diversity and plasticity in signaling pathways that regulate smooth muscle responsiveness: Paradigms and paradoxes for the myosin phosphatase, the master regulator of smooth muscle contraction. J Smooth Muscle Res (2017) 0.77
Smooth muscle-protein translocation and tissue function. Anat Rec (Hoboken) (2014) 0.77
Effects of a fluorescent Myosin light chain phosphatase inhibitor on prostate cancer cells. Front Oncol (2011) 0.77
Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles. J Neurogastroenterol Motil (2016) 0.77
Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle. Age (Dordr) (2011) 0.77
MAPKs represent novel therapeutic targets for gastrointestinal motility disorders. World J Gastrointest Pathophysiol (2011) 0.77
Putative protein partners for the human CPI-17 protein revealed by bacterial two-hybrid screening. Microvasc Res (2013) 0.77
Cholangiocyte myosin IIB is required for localized aggregation of sodium glucose cotransporter 1 to sites of Cryptosporidium parvum cellular invasion and facilitates parasite internalization. Infect Immun (2010) 0.76
A functional interaction between CPI-17 and RACK1 proteins in bronchial smooth muscle cells. Biochem Biophys Res Commun (2010) 0.76
Regulation of urinary bladder function by protein kinase C in physiology and pathophysiology. BMC Urol (2015) 0.76
TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis. Biol Reprod (2016) 0.76
Effects of glyceollin I on vascular contraction in rat aorta. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.76
Calcium desensitisation in late polymicrobial sepsis is associated with loss of vasopressor sensitivity in a murine model. Intensive Care Med Exp (2015) 0.75
The protective role of MLCP-mediated ERM dephosphorylation in endotoxin-induced lung injury in vitro and in vivo. Sci Rep (2016) 0.75
Sustained Contraction in Vascular Smooth Muscle by Activation of L-type Ca(2+) Channels Does Not Involve Ca(2+) Sensitization or Caldesmon. Front Pharmacol (2016) 0.75
3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.75
Identification of novel methylated targets in colorectal cancer by microarray analysis and construction of co-expression network. Oncol Lett (2017) 0.75
Effects of gomisin A on vascular contraction in rat aortic rings. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.75
Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform. J Mol Biol (2017) 0.75
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A (1991) 8.04
Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy (2010) 7.10
Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases. Proc Natl Acad Sci U S A (1994) 6.96
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin. Nature (1989) 5.86
Mrc1 transduces signals of DNA replication stress to activate Rad53. Nat Cell Biol (2001) 5.05
A standard reference frame for the description of nucleic acid base-pair geometry. J Mol Biol (2001) 4.29
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology (2004) 4.24
The PILATUS 1M detector. J Synchrotron Radiat (2006) 4.16
Cross-contamination potential with dental equipment. Lancet (1992) 3.55
Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer (2000) 3.46
A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. Biochem Biophys Res Commun (1985) 3.40
Bacterial genomic reorganization upon DNA replication. Science (2001) 3.25
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet (1999) 3.17
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene (2007) 3.11
A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice. Dev Biol (1999) 3.11
Development of an MRI-compatible needle insertion manipulator for stereotactic neurosurgery. J Image Guid Surg (1995) 3.07
Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice. Neuroreport (2000) 3.04
Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase. Genes Dev (2000) 2.94
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Scarless endoscopic thyroidectomy: breast approach for better cosmesis. Surg Laparosc Endosc Percutan Tech (2000) 2.74
Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol (2001) 2.73
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature (2002) 2.71
A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA. EMBO J (1998) 2.48
Spectrodensitometric determination of trichothecene mycotoxins with 4-(p-nitrobenzyl)pyridine on silica gel thin-layer chromatograms. J Chromatogr (1979) 2.38
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. Circ Res (2005) 2.38
Mutually exclusive expression of odorant receptor transgenes. Nat Neurosci (2000) 2.36
Angiotensin-I-converting enzyme gene polymorphism and susceptibility to cough. Lancet (1994) 2.34
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism. Hum Mol Genet (1999) 2.32
Physiological role of silent receptors of atrial natriuretic factor. Science (1987) 2.31
Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. Science (1999) 2.25
Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia (2009) 2.24
'SPKK' motifs prefer to bind to DNA at A/T-rich sites. EMBO J (1989) 2.24
Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy. Int J Radiat Oncol Biol Phys (1999) 2.19
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature (1989) 2.17
Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase. Mol Cell Biol (2000) 2.17
The natural history of herniated nucleus pulposus with radiculopathy. Spine (Phila Pa 1976) (1996) 2.16
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
Catheter ablation in patients with multiple and unstable ventricular tachycardias after myocardial infarction: short ablation lines guided by reentry circuit isthmuses and sinus rhythm mapping. Circulation (2001) 2.12
Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem (1995) 2.09
Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts. J Bacteriol (1987) 2.08
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology (2001) 2.02
Prenatal DNA diagnosis of a single-gene disorder from maternal plasma. Lancet (2000) 2.01
Analysis of platelet abnormalities in uremia with and without Glanzmann's thrombasthenia. Nephron (1994) 2.00
Solitary fibrous tumour: significance of p53 and CD34 immunoreactivity in its malignant transformation. Histopathology (1998) 2.00
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Curr Biol (2006) 1.98
DNA binding of PhoB and its interaction with RNA polymerase. J Mol Biol (1996) 1.97
Relation between use of health check ups starting in middle age and demand for inpatient care by elderly people in Japan. BMJ (1991) 1.96
Successful screening for early esophageal cancer in alcoholics using endoscopy and mucosa iodine staining. Cancer (1995) 1.91
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain. J Biol Chem (1992) 1.89
Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selection. J Mol Biol (2001) 1.88
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem (1999) 1.87
NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br J Cancer (2005) 1.87
ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun (1991) 1.85
Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study. Proc Natl Acad Sci U S A (1994) 1.83
Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical. Free Radic Biol Med (1996) 1.82
Transposable element in fish. Nature (1996) 1.80
Aneurysms at nonbranching sites in the surpaclinoid portion of the internal carotid artery: internal carotid artery trunk aneurysms. Neurosurgery (2000) 1.80
Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J Biol Chem (1994) 1.78
The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol (2000) 1.74
Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae. J Biol Chem (1997) 1.72
An optical spectrum of the afterglow of a gamma-ray burst at a redshift of z = 6.295. Nature (2006) 1.70
Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics. Carcinogenesis (1998) 1.70
Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Cell (1998) 1.69
Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas. Clin Cancer Res (1997) 1.68
Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging. Br J Cancer (2006) 1.67
Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium. Proc Natl Acad Sci U S A (2000) 1.67
Hypoxic brain damage: cortical laminar necrosis and delayed changes in white matter at sequential MR imaging. Radiology (1993) 1.65
Development of the polymer micelle carrier system for doxorubicin. J Control Release (2001) 1.64
Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels. Biochem Biophys Res Commun (2000) 1.64
Pneumomediastinum in dermatomyositis: association with cutaneous vasculopathy. Ann Rheum Dis (2000) 1.63
Untreated ocular hypertension. A long-term prospective study. Arch Ophthalmol (1977) 1.62
Palmar fasciitis and polyarthritis associated with gastric carcinoma: complete resolution after total gastrectomy. Intern Med (2000) 1.62
Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium. Gut (1998) 1.61
Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI17) in smooth muscle: its specific localization in smooth muscle. FEBS Lett (1997) 1.60
Role of specific determinants in mannan of Candida albicans serotype A in adherence to human buccal epithelial cells. Infect Immun (1992) 1.60
A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34. Immunity (1999) 1.59
Biochemical characterization and intracellular localization of the Menkes disease protein. Proc Natl Acad Sci U S A (1996) 1.59
Silica accumulation in long-lived leaves of Sasa veitchii (Carrière) Rehder (Poaceae-Bambusoideae). Ann Bot (2002) 1.59
Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol (1989) 1.58
Chemosensitivity and p53-Bax pathway-mediated apoptosis in patients with uterine cervical cancer. Ann Oncol (2003) 1.58
High expression of macrophage migration inhibitory factor in human melanoma cells and its role in tumor cell growth and angiogenesis. Biochem Biophys Res Commun (1999) 1.58
Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2). Gene (1990) 1.57
RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions. J Virol (2001) 1.57
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res (1994) 1.55
Analysis and purification of toxic peptides from cyanobacteria by reversed-phase high-performance liquid chromatography. J Chromatogr (1988) 1.55
[Studies on antispetics for foodstuff. LXXI. Studies on orsellinic acid ester, beta-orcinolcarboxylic acid ester and olivetonide as a preservative for sake]. Yakugaku Zasshi (1970) 1.54
Radiation risk to low fluences of alpha particles may be greater than we thought. Proc Natl Acad Sci U S A (2001) 1.53
Toxins contained in Microcystis species of cyanobacteria (blue-green algae). Toxicon (1988) 1.52
Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo. J Exp Med (2000) 1.50
Two distinct forms of peptidylprolyl-cis-trans-isomerase are expressed separately in periplasmic and cytoplasmic compartments of Escherichia coli cells. Biochemistry (1991) 1.50
Biological efficiency and nutritional value of Pleurotus ostreatus cultivated on spent beer grain. Bioresour Technol (2001) 1.50
Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J Immunol (1992) 1.50
Autoantibodies against the amino terminal of alpha-enolase are a useful diagnostic marker of Hashimoto's encephalopathy. J Neuroimmunol (2005) 1.50
Invasion of the lacrimal system by basal cell carcinoma. Dermatol Surg (1999) 1.49