Published in Proc Natl Acad Sci U S A on June 07, 1994
Structure of the cross-beta spine of amyloid-like fibrils. Nature (2005) 11.56
Microsatellites in different eukaryotic genomes: survey and analysis. Genome Res (2000) 7.43
Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell (2004) 6.04
Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc Natl Acad Sci U S A (2008) 4.84
Curli biogenesis and function. Annu Rev Microbiol (2006) 4.77
A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions. Proc Natl Acad Sci U S A (2000) 4.19
Amyloid fibers are water-filled nanotubes. Proc Natl Acad Sci U S A (2002) 3.78
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol Biol Cell (2001) 3.41
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc Natl Acad Sci U S A (1999) 3.33
Hierarchical self-assembly of chiral rod-like molecules as a model for peptide beta -sheet tapes, ribbons, fibrils, and fibers. Proc Natl Acad Sci U S A (2001) 2.96
Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure. Proc Natl Acad Sci U S A (2006) 2.88
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2000) 2.63
The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation. EMBO J (2002) 2.59
Solid-state NMR studies of amyloid fibril structure. Annu Rev Phys Chem (2011) 2.38
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation. J Cell Biol (1998) 2.37
A role for Q/N-rich aggregation-prone regions in P-body localization. J Cell Sci (2008) 2.30
Aggregation of proteins with expanded glutamine and alanine repeats of the glutamine-rich and asparagine-rich domains of Sup35 and of the amyloid beta-peptide of amyloid plaques. Proc Natl Acad Sci U S A (2002) 2.23
Interaction of Huntington disease protein with transcriptional activator Sp1. Mol Cell Biol (2002) 2.19
Simple tandem DNA repeats and human genetic disease. Proc Natl Acad Sci U S A (1995) 2.18
Amino acid runs in eukaryotic proteomes and disease associations. Proc Natl Acad Sci U S A (2002) 2.17
Molecular features of the copper binding sites in the octarepeat domain of the prion protein. Biochemistry (2002) 2.16
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. J Biol Chem (2010) 2.10
Solubilization and disaggregation of polyglutamine peptides. Protein Sci (2001) 2.00
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions. Proc Natl Acad Sci U S A (2006) 2.00
Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development. Proc Natl Acad Sci U S A (1996) 1.99
Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity. Proc Natl Acad Sci U S A (2009) 1.96
Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy. Proc Natl Acad Sci U S A (2000) 1.88
Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases. Proc Natl Acad Sci U S A (1995) 1.86
Proteasomal dysfunction in aging and Huntington disease. Neurobiol Dis (2010) 1.85
Prediction of aggregation rate and aggregation-prone segments in polypeptide sequences. Protein Sci (2005) 1.80
Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p. Biochemistry (2005) 1.79
"Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+]. J Mol Biol (2006) 1.74
Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions. J Clin Invest (2002) 1.65
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proc Natl Acad Sci U S A (2002) 1.65
Rational design and application of responsive alpha-helical peptide hydrogels. Nat Mater (2009) 1.63
Specificity in intracellular protein aggregation and inclusion body formation. Proc Natl Acad Sci U S A (2001) 1.62
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.60
The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation. Proc Natl Acad Sci U S A (2005) 1.60
Altered transcription in yeast expressing expanded polyglutamine. Proc Natl Acad Sci U S A (2001) 1.58
YaeL proteolysis of RseA is controlled by the PDZ domain of YaeL and a Gln-rich region of RseA. EMBO J (2003) 1.55
Two prion-inducing regions of Ure2p are nonoverlapping. Mol Cell Biol (1999) 1.53
Poly-L-glutamine forms cation channels: relevance to the pathogenesis of the polyglutamine diseases. Biophys J (2000) 1.53
Polar zippers: their role in human disease. Protein Sci (1994) 1.53
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc Natl Acad Sci U S A (1995) 1.50
The structural biology of protein aggregation diseases: Fundamental questions and some answers. Acc Chem Res (2006) 1.47
Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43. J Biol Chem (2010) 1.47
Protein aggregates in Huntington's disease. Exp Neurol (2011) 1.46
Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold. Am J Hum Genet (1999) 1.45
A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast. Mol Cell (2007) 1.43
Atomistic simulations of the effects of polyglutamine chain length and solvent quality on conformational equilibria and spontaneous homodimerization. J Mol Biol (2008) 1.43
An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta -fibrils. Proc Natl Acad Sci U S A (2001) 1.38
Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei. Proc Natl Acad Sci U S A (1999) 1.37
The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils. J Am Chem Soc (2011) 1.37
Physical chemistry of polyglutamine: intriguing tales of a monotonous sequence. J Mol Biol (2012) 1.37
Direct conversion of an oligopeptide from a beta-sheet to an alpha-helix: a model for amyloid formation. Proc Natl Acad Sci U S A (1997) 1.36
Amino acid repeat patterns in protein sequences: their diversity and structural-functional implications. Protein Sci (2000) 1.36
Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system. Proc Natl Acad Sci U S A (1996) 1.34
Rapid amyloid fiber formation from the fast-folding WW domain FBP28. Proc Natl Acad Sci U S A (2003) 1.33
Two prion variants of Sup35p have in-register parallel beta-sheet structures, independent of hydration. Biochemistry (2009) 1.30
Modulation of polyglutamine conformations and dimer formation by the N-terminus of huntingtin. J Mol Biol (2009) 1.30
Transposon telomeres are widely distributed in the Drosophila genus: TART elements in the virilis group. Proc Natl Acad Sci U S A (2003) 1.30
Molecular structures of amyloid and prion fibrils: consensus versus controversy. Acc Chem Res (2013) 1.29
Evidence for a recruitment and sequestration mechanism in Huntington's disease. Philos Trans R Soc Lond B Biol Sci (1999) 1.25
Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Proc Natl Acad Sci U S A (2007) 1.24
Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton. Mol Cell (2011) 1.24
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2011) 1.23
Molecular dynamics analyses of cross-beta-spine steric zipper models: beta-sheet twisting and aggregation. Proc Natl Acad Sci U S A (2006) 1.22
Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response. Am J Physiol Cell Physiol (2008) 1.20
Potential aggregation prone regions in biotherapeutics: A survey of commercial monoclonal antibodies. MAbs (2009) 1.20
Biased distribution of microsatellite motifs in the rice genome. Mol Genet Genomics (2007) 1.19
Unscrambling an egg: protein disaggregation by AAA+ proteins. Microb Cell Fact (2004) 1.19
Prions in Saccharomyces and Podospora spp.: protein-based inheritance. Microbiol Mol Biol Rev (1999) 1.19
HeT-A and TART, two Drosophila retrotransposons with a bona fide role in chromosome structure for more than 60 million years. Cytogenet Genome Res (2005) 1.18
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease. Philos Trans R Soc Lond B Biol Sci (1999) 1.18
Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases. Proc Natl Acad Sci U S A (2005) 1.18
The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity. Mol Cell Biol (2000) 1.18
Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid. Proc Natl Acad Sci U S A (1995) 1.18
Polyglutamine induced misfolding of huntingtin exon1 is modulated by the flanking sequences. PLoS Comput Biol (2010) 1.17
Amyloid fibrils: abnormal protein assembly. Prion (2008) 1.15
Huntingtin in health and disease. J Clin Invest (2003) 1.14
Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration. Cerebellum (2008) 1.11
Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: cellular population-dependent dynamics of mitotic instability. Am J Hum Genet (1996) 1.10
Prion variants and species barriers among Saccharomyces Ure2 proteins. Genetics (2009) 1.10
Structure of core domain of fibril-forming PHF/Tau fragments. Biophys J (2005) 1.09
Prion-prion interactions. Prion (2007) 1.08
Kennedy disease. J Inherit Metab Dis (1997) 1.06
Expression and function of Dlx genes in the osteoblast lineage. Dev Biol (2008) 1.04
Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain. Neuron (2012) 1.04
Oligomerization of bovine ribonuclease A: structural and functional features of its multimers. Biochem J (2004) 1.03
Prion diseases of yeast: amyloid structure and biology. Semin Cell Dev Biol (2011) 1.03
Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias. Cerebellum (2014) 1.03
Neurodegenerative processes in Huntington's disease. Cell Death Dis (2011) 1.03
Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. Proc Natl Acad Sci U S A (1996) 1.03
The core of Ure2p prion fibrils is formed by the N-terminal segment in a parallel cross-β structure: evidence from solid-state NMR. J Mol Biol (2011) 1.03
Nonneural nuclear inclusions of androgen receptor protein in spinal and bulbar muscular atrophy. Am J Pathol (1998) 1.02
Side-chain interactions determine amyloid formation by model polyglutamine peptides in molecular dynamics simulations. Biophys J (2006) 1.02
Ontology and diversity of transcript-associated microsatellites mined from a globe artichoke EST database. BMC Genomics (2009) 1.02
Prion amyloid structure explains templating: how proteins can be genes. FEMS Yeast Res (2010) 1.01
Codon repeats in genes associated with human diseases: fewer repeats in the genes of nonhuman primates and nucleotide substitutions concentrated at the sites of reiteration. Proc Natl Acad Sci U S A (1996) 1.01
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell (1987) 12.30
Computed circular dichroism spectra for the evaluation of protein conformation. Biochemistry (1969) 10.58
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature (1991) 9.89
Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nat Genet (1993) 7.97
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49
Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nat Genet (1994) 4.36
Cloning of a transcriptionally active human TATA binding factor. Science (1990) 4.18
The Drosophila fsh locus, a maternal effect homeotic gene, encodes apparent membrane proteins. Dev Biol (1989) 2.35
Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophy. Nat Genet (1992) 2.18
Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy. Nat Genet (1993) 1.93
Structure of beta-poly-L-alanine: refined atomic co-ordinates for an anti-parallel beta-pleated sheet. J Mol Biol (1967) 1.87
Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci (1993) 1.82
Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain. Genes Dev (1993) 1.74
Characterization and localization of the Huntington disease gene product. Hum Mol Genet (1993) 1.60
Polar zippers. Curr Biol (1993) 1.48
Presymptomatic analysis of spinocerebellar ataxia type 1 (SCA1) via the expansion of the SCA1 CAG-repeat in a large pedigree displaying anticipation and parental male bias. Hum Mol Genet (1993) 1.29
Molecular genetics of neurological diseases. Science (1993) 1.27
Functional dissection of Drosophila abdominal-B protein. Mech Dev (1991) 1.20
Beta-pleated sheets in oligopeptide crystals. Int J Pept Protein Res (1981) 1.16
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Antisense transcription in the mammalian transcriptome. Science (2005) 15.69
Structure of yeast phenylalanine tRNA at 3 A resolution. Nature (1974) 10.27
Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci U S A (1991) 8.04
Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. Lancet (1998) 7.70
The structure of an oligo(dA).oligo(dT) tract and its biological implications. Nature (1987) 7.23
Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy (2010) 7.10
Solenoidal model for superstructure in chromatin. Proc Natl Acad Sci U S A (1976) 6.65
Assembly and analysis of conical models for the HIV-1 core. Science (1999) 6.35
Structure of nucleosome core particles of chromatin. Nature (1977) 6.24
Structure of the nucleosome core particle at 7 A resolution. Nature (1984) 6.16
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin. Nature (1989) 5.86
The mechanism of Z alpha 1-antitrypsin accumulation in the liver. Nature (1992) 5.71
Image reconstructions of helical assemblies of the HIV-1 CA protein. Nature (2000) 5.60
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding. Nature (1993) 4.81
The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell (1995) 4.79
Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA. Nature (1978) 4.56
A standard reference frame for the description of nucleic acid base-pair geometry. J Mol Biol (2001) 4.29
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology (2004) 4.24
The PILATUS 1M detector. J Synchrotron Radiat (2006) 4.16
Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. Gastroenterology (2001) 3.85
The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition. Nature (1993) 3.82
Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiol Scand (2003) 3.79
Amyloid fibers are water-filled nanotubes. Proc Natl Acad Sci U S A (2002) 3.78
A spacer protein in the Saccharomyces cerevisiae spindle poly body whose transcript is cell cycle-regulated. J Cell Biol (1993) 3.71
Cross-contamination potential with dental equipment. Lancet (1992) 3.55
The evolution of mutation rates: separating causes from consequences. Bioessays (2000) 3.48
On the structure of coated vesicles. J Mol Biol (1976) 3.47
Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer (2000) 3.46
A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. Biochem Biophys Res Commun (1985) 3.40
Bacterial genomic reorganization upon DNA replication. Science (2001) 3.25
A low resolution structure for the histone core of the nucleosome. Nature (1980) 3.17
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet (1999) 3.17
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene (2007) 3.11
A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice. Dev Biol (1999) 3.11
Development of an MRI-compatible needle insertion manipulator for stereotactic neurosurgery. J Image Guid Surg (1995) 3.07
Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice. Neuroreport (2000) 3.04
Electron microscopy of defined lengths of chromatin. Proc Natl Acad Sci U S A (1975) 2.99
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell (1993) 2.95
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature (2002) 2.71
The structure of viruses of the papilloma-polyoma type 3. Structure of rabbit papilloma virus, with an appendix on the topography of contrast in negative-staining for electron-microscopy. J Mol Biol (1965) 2.65
Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods. Gene Ther (2002) 2.59
Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol (1993) 2.57
Vertical strabismus after cataract surgery. Ophthalmology (1996) 2.56
A novel mode of DNA recognition by a beta-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA. EMBO J (1998) 2.48
Does the higher order structure of the influenza virus ribonucleoprotein guide sequence rearrangements in influenza viral RNA? Cell (1983) 2.42
Spectrodensitometric determination of trichothecene mycotoxins with 4-(p-nitrobenzyl)pyridine on silica gel thin-layer chromatograms. J Chromatogr (1979) 2.38
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. Circ Res (2005) 2.38
Mutually exclusive expression of odorant receptor transgenes. Nat Neurosci (2000) 2.36
Structure of sickled erythrocytes and of sickle-cell hemoglobin fibers. Proc Natl Acad Sci U S A (1973) 2.32
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism. Hum Mol Genet (1999) 2.32
Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Diabetologia (2009) 2.32
Physiological role of silent receptors of atrial natriuretic factor. Science (1987) 2.31
Three dimensional reconstructions of spherical viruses by fourier synthesis from electron micrographs. Nature (1970) 2.29
Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. Science (1999) 2.25
Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia (2009) 2.24
'SPKK' motifs prefer to bind to DNA at A/T-rich sites. EMBO J (1989) 2.24
Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy. Int J Radiat Oncol Biol Phys (1999) 2.19
Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs. Proc Natl Acad Sci U S A (1991) 2.19
Regulation of skeletal muscle contraction. II. Structural studies of the interaction of the tropomyosin-troponin complex with actin. J Mol Biol (1972) 2.17
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature (1989) 2.17
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
Catheter ablation in patients with multiple and unstable ventricular tachycardias after myocardial infarction: short ablation lines guided by reentry circuit isthmuses and sinus rhythm mapping. Circulation (2001) 2.12
Quantitation of epidermal nerves in diabetic neuropathy. Neurology (1996) 2.12
Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem (1995) 2.09
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease. Int J Cancer (1973) 2.05
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology (2001) 2.02
Prenatal DNA diagnosis of a single-gene disorder from maternal plasma. Lancet (2000) 2.01
Analysis of platelet abnormalities in uremia with and without Glanzmann's thrombasthenia. Nephron (1994) 2.00
Solitary fibrous tumour: significance of p53 and CD34 immunoreactivity in its malignant transformation. Histopathology (1998) 2.00
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Curr Biol (2006) 1.98
Differences in somatic perception in female patients with irritable bowel syndrome with and without fibromyalgia. Pain (2000) 1.97
DNA binding of PhoB and its interaction with RNA polymerase. J Mol Biol (1996) 1.97
Relation between use of health check ups starting in middle age and demand for inpatient care by elderly people in Japan. BMJ (1991) 1.96
A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. J Biochem (1995) 1.92
Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation. Pain (1999) 1.90
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain. J Biol Chem (1992) 1.89
Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selection. J Mol Biol (2001) 1.88
Familial dementia caused by polymerization of mutant neuroserpin. Nature (1999) 1.88
Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem (1999) 1.87
NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br J Cancer (2005) 1.87
ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun (1991) 1.85
Promotion of parallel DNA quadruplexes by a yeast telomere binding protein: a circular dichroism study. Proc Natl Acad Sci U S A (1994) 1.83
Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical. Free Radic Biol Med (1996) 1.82
Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: correlation with sensory function. J Neurosci (1998) 1.82
X-ray diffraction study of a new crystal form of the nucleosome core showing higher resolution. J Mol Biol (1981) 1.81
Transposable element in fish. Nature (1996) 1.80
Aneurysms at nonbranching sites in the surpaclinoid portion of the internal carotid artery: internal carotid artery trunk aneurysms. Neurosurgery (2000) 1.80
Maternal bisphenol-A levels at delivery: a looming problem? J Perinatol (2008) 1.78
Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J Biol Chem (1994) 1.78
A randomised controlled study of close monitoring of vulnerable psychiatric patients. Lancet (1995) 1.76
A consensus amino-acid sequence repeat in Torpedo and mammalian Ca2+-dependent membrane-binding proteins. Nature (1986) 1.76
The 5' upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol (2000) 1.74
Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae. J Biol Chem (1997) 1.72
The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Mol Cell Biol (1995) 1.71
An optical spectrum of the afterglow of a gamma-ray burst at a redshift of z = 6.295. Nature (2006) 1.70
Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Cell (1998) 1.69
Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas. Clin Cancer Res (1997) 1.68