C S Patlak

Author PubWeight™ 106.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977 11.55
2 Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983 9.59
3 Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations. J Cereb Blood Flow Metab 1985 5.99
4 The flow of solute and solvent across a two-membrane system. J Theor Biol 1963 4.70
5 Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem 1996 1.96
6 Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. J Cereb Blood Flow Metab 1983 1.80
7 Efflux of radiolabeled polyethylene glycols and albumin from rat brain. Am J Physiol 1981 1.62
8 Drainage of interstitial fluid from different regions of rat brain. Am J Physiol 1984 1.58
9 Measurements of dog blood-brain transfer constants by ventriculocisternal perfusion. Am J Physiol 1975 1.56
10 Striatal 18F-dopa uptake: absence of an aging effect. J Cereb Blood Flow Metab 1993 1.52
11 Local cerebral glucose utilization in controlled graded levels of hyperglycemia in the conscious rat. J Cereb Blood Flow Metab 1988 1.49
12 Effects of postnatal dexamethasone on blood-brain barrier permeability and brain water content in newborn lambs. Am J Physiol Regul Integr Comp Physiol 2001 1.44
13 Characteristics of p-aminohippurate transport in proximal renal tubules. Am J Physiol 1969 1.43
14 Sucrose and inulin space measurements of cerebral cortex in four mammalian species. Am J Physiol 1970 1.32
15 Albumin outflow into deep cervical lymph from different regions of rabbit brain. Am J Physiol 1991 1.23
16 A method to obtain infusion schedules for prescribed blood concentration time courses. J Appl Physiol 1976 1.15
17 A component of fluid absorption linked to passive ion flows in the superficial pars recta. J Gen Physiol 1975 1.13
18 Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults. Am J Physiol 1996 1.11
19 Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypernatremia. J Physiol 1991 1.10
20 Theoretical analysis of net tracer flux due to volume circulation in a membrane with pores of different sizes. Relation to solute drag model. J Gen Physiol 1971 1.10
21 An evaluation of errors in the determination of blood flow by the indicator fractionation and tissue equilibration (Kety) methods. J Cereb Blood Flow Metab 1984 1.05
22 Quantitative autoradiographic studies of brain edema and a comparison of multi-isotope autoradiographic techniques. Adv Neurol 1980 1.03
23 Volume absorption in the pars recta. II. Hydraulic conductivity coefficient. Am J Physiol 1978 1.03
24 Nigrostriatal function in humans studied with positron emission tomography. Ann Neurol 1989 1.03
25 Volume regulatory loss of Na, Cl, and K from rat brain during acute hyponatremia. Am J Physiol 1987 1.00
26 Transport of material between brain extracellular fluid, brain cells and blood. Fed Proc 1974 1.00
27 Methods for Quantifying the transport of drugs across brain barrier systems. Pharmacol Ther 1981 0.99
28 A critical evaluation of the principles governing the advantages of intra-arterial infusions. J Pharmacokinet Biopharm 1974 0.98
29 Selection of experimental conditions for the accurate determination of blood--brain transfer constants from single-time experiments: a theoretical analysis. J Cereb Blood Flow Metab 1983 0.97
30 Increased blood-brain transfer in a rabbit model of acute liver failure. Gastroenterology 1983 0.95
31 Convection of cerebral interstitial fluid and its role in brain volume regulation. Ann N Y Acad Sci 1986 0.95
32 Volume regulatory influx of electrolytes from plasma to brain during acute hyperosmolality. Am J Physiol 1987 0.94
33 Antenatal steroids decrease blood-brain barrier permeability in the ovine fetus. Am J Physiol 1999 0.94
34 Dexamethasone effects on [125I]albumin distribution in experimental RG-2 gliomas and adjacent brain. J Cereb Blood Flow Metab 1987 0.93
35 Susceptibility changes following bolus injections. Magn Reson Med 1993 0.93
36 Fluid absorption and active and passive ion flows in the rabbit superficial pars recta. Am J Physiol 1977 0.91
37 Quantitative evaluation of the loss of human platelet dense bodies following stimulation by thrombin or A23187. J Physiol 1977 0.89
38 Local blood-to-tissue transport in Walker 256 metastatic brain tumors. J Neurooncol 1984 0.89
39 Osmosis in cortical collecting tubules. A theoretical and experimental analysis of the osmotic transient phenomenon. J Gen Physiol 1974 0.89
40 Regulation of brain water and electrolytes during acute hyperosmolality in rats. Am J Physiol 1987 0.88
41 A spatial analysis of the blood-brain barrier damage in experimental allergic encephalomyelitis. J Cereb Blood Flow Metab 1985 0.88
42 Kinetic analysis of blood-brain barrier transport of D-glucose in man: quantitative evaluation in the presence of tracer backflux and capillary heterogeneity. Microvasc Res 1990 0.86
43 Dexamethasone effects on vascular volume and tissue hematocrit in experimental RG-2 gliomas and adjacent brain. J Neurooncol 1988 0.86
44 Cerebrovascular transport of [125I]quinuclidinyl benzilate, [3H]cyclofoxy, and [14C]iodoantipyrine. Am J Physiol 1990 0.86
45 Brain ion and volume regulation during acute hypernatremia in Brattleboro rats. Am J Physiol 1989 0.85
46 Heuristic modeling of drug delivery to malignant brain tumors. J Pharmacokinet Biopharm 1980 0.85
47 The influence of tissue heterogeneity on results of fitting nonlinear model equations to regional tracer uptake curves: with an application to compartmental models used in positron emission tomography. J Cereb Blood Flow Metab 1987 0.85
48 Metabolic and kinetic considerations in the use of [125I]HIPDM for quantitative measurement of regional cerebral blood flow. J Cereb Blood Flow Metab 1985 0.85
49 Quantitative measurements of capillary transport in human brain tumors by computed tomography. Ann Neurol 1991 0.84
50 Alterations in hepatic production and peripheral clearance of IGF-I after endotoxin. Am J Physiol 1995 0.84
51 A theoretical treatmnt for the kinetics of monolayer desorption from interfaces. J Colloid Interface Sci 1967 0.84
52 Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy. Cancer Res 1987 0.83
53 A method to quantitatively measure transcapillary transport of iodinated compounds in canine brain tumors with computed tomography. J Cereb Blood Flow Metab 1991 0.83
54 Analysis of brain uptake and loss or radiotracers after intracarotid injection. Am J Physiol 1975 0.83
55 Variation in local cerebral blood flow response to high-dose pentobarbital sodium in the rat. Am J Physiol 1991 0.83
56 Effects of arginine vasopressin and atriopeptin on glial cell volume measured as 3-MG space. Am J Physiol 1993 0.82
57 Distribution of methotrexate in the cerebrospinal fluid and brain after intraventricular administration. Cancer Treat Rep 1977 0.82
58 Cerebral blood volume measurements by T*2-weighted MRI and contrast infusion. Magn Reson Med 2003 0.82
59 Adaptation of protein metabolism in relation to limits to high dietary protein intake. Eur J Clin Nutr 1999 0.81
60 Local cerebral glucose utilization in fetal and neonatal sheep. Am J Physiol 1984 0.80
61 Asymmetrical transport of amino acids across the blood-brain barrier in humans. J Cereb Blood Flow Metab 1990 0.80
62 Effect of vasopressin on ependymal and capillary permeability to tritiated water in cat. Am J Physiol 1986 0.80
63 Effects of duration of positive-pressure ventilation on blood-brain barrier function in premature lambs. J Appl Physiol (1985) 2000 0.80
64 Changes in blood-brain transfer parameters induced by hyperosmolar intracarotid infusion and by metastatic tumor growth. Adv Exp Med Biol 1980 0.79
65 Derivation of equations for the steady-state reaction velocity of a substance based on the use of a second substance. J Cereb Blood Flow Metab 1981 0.79
66 Regional blood flow, capillary permeability, and glucose utilization in two brain tumor models: preliminary observations and pharmacokinetic implications. Cancer Treat Rep 1981 0.79
67 Kinetic analysis of cerebrovascular transport based on indicator diffusion technique. Am J Physiol 1989 0.79
68 A compartmental analysis of 24 Na kinetics in rat cerebrum, sciatic nerve and cerebrospinal fluid. J Physiol 1972 0.79
69 Fluid flow rates in human peritumoural oedema. Acta Neurochir Suppl (Wien) 1990 0.79
70 The microcirculation of rat circumventricular organs and pituitary gland. Brain Res Bull 1987 0.79
71 Contribution of leaked load to solute transport by renal tubules. Am J Physiol 1978 0.78
72 Analysis of the distribution of materials within the blood-brain-cerebrospinal fluid system. Bull Math Biophys 1967 0.78
73 Local blood flow in Walker 256 metastatic brain tumors. J Neurooncol 1984 0.77
74 Analysis of in vitro glucose utilization in a circadian pacemaker model. J Neurosci 1992 0.77
75 Kinetic model of 2-deoxyglucose metabolism using brain slices. J Cereb Blood Flow Metab 1990 0.77
76 Permeability limitation in estimation of local brain blood flow with [14C]antipyrine. Am J Physiol 1975 0.77
77 Apparent glucose utilization in Walker 256 metastatic brain tumors. J Neurooncol 1986 0.76
78 Rapid dynamic CT scanning to distinguish schizophrenic from normal subjects. Psychiatry Res 1987 0.76
79 The role of unstirred layers for water exchange across the blood-brain barrier. Microvasc Res 1981 0.76
80 Simplified brain slice glucose utilization. J Cereb Blood Flow Metab 1996 0.76
81 Brain slice glucose utilization. J Neurochem 1988 0.75
82 Kinetic analysis of transport and opioid receptor binding of [3H](-)-cyclofoxy in rat brain in vivo: implications for human studies. J Cereb Blood Flow Metab 1991 0.75
83 In situ drug delivery. Br J Cancer Suppl 1980 0.75
84 Blood-brain barrier permeability measurements by double-indicator method using intravenous injection. Am J Physiol 1994 0.75
85 Rapid amino acid uptake in rat pituitary neural lobe during functional stimulation by chronic dehydration. J Cereb Blood Flow Metab 1985 0.75
86 Homovanillic acid transport by the spinal cord. Neurology 1976 0.75
87 Transport of 5-hydroxy-3-indoleacetic acid by spinal cord during subarachnoid perfusion. Brain Res 1976 0.75
88 On expectations of some functions of Poisson variates. Biometrics 1968 0.75
89 Effects of K+, pH and glutamate on 45Ca kinetics in hippocampal brain slices. J Neurosci Methods 1995 0.75
90 CNS, CSF, and extradural fluid uptake of various hydrophilic materials in the dogfish. Am J Physiol 1977 0.75
91 Increased peritoneal solute transport in diabetic peritoneal dialysis patients. Adv Perit Dial 1995 0.75
92 Use of transient and steady- state measurements of the unidirectional flux ratio for the determination of the free energy change of chemical reactions and active transport systems. Bull Math Biol 1980 0.75
93 Fluid absorption and active and passive ion flows in the rabbit superficial pars recta. J Am Soc Nephrol 2000 0.75
94 Correlations between plasminogen activator inhibitor-1 and peritoneal transport in pediatric CCPD patients. Perit Dial Int 1995 0.75
95 Drug delivery to CNS tumors. Cancer Treat Rep 1981 0.75
96 3-Methoxy-4-hydroxyphenylethyleneglycol (mhpg) transport from the spinal cord during spinal subarachnoid perfusion. Brain Res 1976 0.75
97 Volume and ion regulation in both intracellular and extracellular compartments determined by diffusion, gravimetric and ion analysis. Acta Physiol Scand Suppl 1989 0.75
98 Apparent glucose utilization in Walker 256 metastatic brain tumors. J Neurooncol 1985 0.75
99 An approximation diffusion equation for a long narrow channel with varying cross-sectional area. Bull Math Biol 1974 0.75
100 Cross-flow membrane plasmapheresis technique for continuous ex vivo plasma sampling. J Pharmacol Toxicol Methods 1994 0.75
101 [Effects of dehydration of the pituitary microcirculation in rats]. No To Shinkei 1989 0.75
102 Estimation of blood sampling errors resulting from metabolism and solute exchange between plasma and formed elements. J Pharmacol Toxicol Methods 1994 0.75