Published in Genes Dev on October 15, 1996
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. EMBO J (1999) 3.05
Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins. J Cell Sci (1999) 2.51
Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity. Mol Cell Biol (1999) 2.42
The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks. Proc Natl Acad Sci U S A (1999) 2.41
Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation. Genes Dev (1997) 2.34
Establishing the program of origin firing during S phase in fission Yeast. Cell (2009) 2.20
Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase. Mol Cell Biol (2000) 2.17
Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18. EMBO J (2000) 1.91
Association of fission yeast Orp1 and Mcm6 proteins with chromosomal replication origins. Mol Cell Biol (1999) 1.79
Clustered adenine/thymine stretches are essential for function of a fission yeast replication origin. Mol Cell Biol (1999) 1.65
Site-specific DNA binding of the Schizosaccharomyces pombe origin recognition complex is determined by the Orc4 subunit. Mol Cell Biol (2001) 1.56
Regulating DNA replication in eukarya. Cold Spring Harb Perspect Biol (2013) 1.52
E2F mediates developmental and cell cycle regulation of ORC1 in Drosophila. EMBO J (1999) 1.44
Nuclear localization of Schizosaccharomyces pombe Mcm2/Cdc19p requires MCM complex assembly. Mol Biol Cell (1999) 1.42
Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast. Mol Biol Cell (2001) 1.42
Multiple orientation-dependent, synergistically interacting, similar domains in the ribosomal DNA replication origin of the fission yeast, Schizosaccharomyces pombe. Mol Cell Biol (1998) 1.40
A fission yeast gene, him1(+)/dfp1(+), encoding a regulatory subunit for Hsk1 kinase, plays essential roles in S-phase initiation as well as in S-phase checkpoint control and recovery from DNA damage. Mol Cell Biol (1999) 1.39
Assembly of functionally active Drosophila origin recognition complex from recombinant proteins. Genes Dev (1999) 1.37
Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication. EMBO J (2001) 1.36
Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated. Mol Cell Biol (2000) 1.31
Schizosaccharomyces pombe cdc20+ encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint. Proc Natl Acad Sci U S A (1997) 1.31
Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Nucleic Acids Res (2002) 1.27
Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A (1999) 1.27
Multiple domains of fission yeast Cdc19p (MCM2) are required for its association with the core MCM complex. Mol Biol Cell (1998) 1.27
Mutational effect of fission yeast polalpha on cell cycle events. Mol Biol Cell (1998) 1.26
Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. Mol Cell Biol (2000) 1.24
Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma. Proc Natl Acad Sci U S A (2001) 1.22
DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts. Biochem J (2000) 1.21
Mutator phenotype induced by aberrant replication. Mol Cell Biol (1999) 1.18
Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity. Genetics (1998) 1.17
Functions of fission yeast orp2 in DNA replication and checkpoint control. Genetics (2000) 1.11
Site-specific ORC binding, pre-replication complex assembly and DNA synthesis at Schizosaccharomyces pombe replication origins. EMBO J (2002) 1.03
Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints. Genetics (2001) 1.02
A novel function of the DNA repair gene rhp6 in mating-type silencing by chromatin remodeling in fission yeast. Mol Cell Biol (1998) 0.94
Rereplication phenomenon in fission yeast requires MCM proteins and other S phase genes. Genetics (1999) 0.93
The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication. Mol Cell Biol (2004) 0.91
A screen for Schizosaccharomyces pombe mutants defective in rereplication identifies new alleles of rad4+, cut9+ and psf2+. Genetics (2004) 0.89
Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast. Mol Biol Cell (2015) 0.89
Brc1-dependent recovery from replication stress. J Cell Sci (2012) 0.88
The role of nucleotide binding and hydrolysis in the function of the fission yeast cdc18(+) gene product. Genetics (1999) 0.85
Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage. Genetics (2010) 0.83
Schizosaccharomyces pombe minichromosome maintenance-binding protein (MCM-BP) antagonizes MCM helicase. J Biol Chem (2011) 0.83
Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication. Biochim Biophys Acta (2011) 0.81
Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells. J Biol Chem (2015) 0.80
Mechanisms and regulation of DNA replication initiation in eukaryotes. Crit Rev Biochem Mol Biol (2017) 0.79
PombeX: robust cell segmentation for fission yeast transillumination images. PLoS One (2013) 0.79
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol (1991) 33.90
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature (1989) 11.90
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1976) 9.64
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature (1987) 8.87
cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell (1986) 8.82
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell (1987) 8.76
Genetic control of cell size at cell division in yeast. Nature (1975) 7.74
Animal cell cycles and their control. Annu Rev Biochem (1992) 6.60
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. Cell (1988) 6.29
The fission yeast cdc18+ gene product couples S phase to START and mitosis. Cell (1993) 6.25
Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature (1981) 5.98
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell (1990) 5.42
Regulation of p34cdc2 protein kinase during mitosis. Cell (1989) 5.33
Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation. Mol Gen Genet (1982) 5.17
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation. Cell (1986) 4.73
Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev (1992) 4.62
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature (1991) 4.60
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J (1991) 4.59
The Cdt1 protein is required to license DNA for replication in fission yeast. Nature (2000) 4.46
Substrates for p34cdc2: in vivo veritas? Cell (1990) 4.34
Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. Exp Cell Res (1977) 4.31
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J (1991) 4.04
Growth in cell length in the fission yeast Schizosaccharomyces pombe. J Cell Sci (1985) 3.99
Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1981) 3.87
Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 'start' gene. EMBO J (1985) 3.87
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis. Cell (1987) 3.82
Functionally homologous cell cycle control genes in budding and fission yeast. Nature (1982) 3.78
p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase. EMBO J (1989) 3.70
Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene. Nature (1994) 3.56
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex. Cell (1994) 3.52
cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol (1997) 3.46
Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. Genetics (1980) 3.42
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J (1997) 3.38
Cohesin Rec8 is required for reductional chromosome segregation at meiosis. Nature (1999) 3.35
p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell (1995) 3.29
CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell (2000) 3.21
tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell. Cell (1997) 3.15
Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annu Rev Cell Biol (1991) 3.14
Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature (1989) 3.12
Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation. Cell (1989) 3.05
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. J Cell Sci (1996) 3.01
Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. J Cell Sci (1988) 2.96
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein. Nature (1988) 2.88
Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast. Nature (1990) 2.86
A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell (1990) 2.84
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Mol Cell Biol (1989) 2.75
Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence. Nature (1985) 2.74
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell (1990) 2.73
Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+. Nature (1988) 2.71
Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science (1990) 2.63
Vectors for the construction of gene banks and the integration of cloned genes in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Plasmid (1986) 2.58
A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins. EMBO J (1996) 2.58
A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. Trends Genet (1996) 2.54
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase. Cell (1995) 2.48
Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell (1991) 2.47
The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function. Mol Gen Genet (1986) 2.46
Expression of the SV40 promoter in fission yeast: identification and characterization of an AP-1-like factor. Cell (1988) 2.44
Periodic transcription as a means of regulating gene expression during the cell cycle: contrasting modes of expression of DNA ligase genes in budding and fission yeast. EMBO J (1986) 2.29
Controls over the timing of DNA replication during the cell cycle of fission yeast. Exp Cell Res (1977) 2.27
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle. J Cell Biol (1995) 2.26
Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. Proc Natl Acad Sci U S A (1998) 2.20
A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO J (1994) 2.15
cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe. Mol Biol Cell (1998) 2.11
Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe. J Bacteriol (1979) 2.06
Schizosaccharomyces pombe and Saccharomyces cerevisiae: a look at yeasts divided. Cell (1986) 2.06
Mutants altered in the control co-ordinating cell division with cell growth in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1978) 2.03
Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2+ protein structure and function. Mol Gen Genet (1989) 2.02
suc1 is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J (1986) 1.99
Regulation of cell polarity by microtubules in fission yeast. J Cell Biol (1998) 1.88
Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth. EMBO J (1994) 1.87
How fission yeast fission in the middle. Cell (1996) 1.81
DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. J Cell Sci (1995) 1.79
Cell cycle control genes in fission yeast and mammalian cells. Trends Genet (1988) 1.77
twine, a cdc25 homolog that functions in the male and female germline of Drosophila. Cell (1992) 1.77
Control of the higher eukaryote cell cycle by p34cdc2 homologues. Biochim Biophys Acta (1989) 1.74
Transcription of the cdc2 cell cycle control gene of the fission yeast Schizosaccharomyces pombe. EMBO J (1986) 1.73
Pre-meiotic S phase is linked to reductional chromosome segregation and recombination. Nature (2001) 1.71
Control of the timing of cell division in fission yeast. Cell size mutants reveal a second control pathway. Exp Cell Res (1978) 1.68
Isolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA. EMBO J (1992) 1.68
Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string. EMBO J (1990) 1.64
Identification of a G1-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe. Nature (1991) 1.62
Microtubules mediate mitochondrial distribution in fission yeast. Proc Natl Acad Sci U S A (1996) 1.60
Identification of fission yeast nuclear markers using random polypeptide fusions with green fluorescent protein. Proc Natl Acad Sci U S A (1996) 1.59
A journey into space. Nat Rev Mol Cell Biol (2001) 1.59
Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe. Genetics (1991) 1.58
The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue. Nucleic Acids Res (1995) 1.55
Premature chromatin condensation upon accumulation of NIMA. EMBO J (1994) 1.52
The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. EMBO J (1996) 1.49
Tea2p is a kinesin-like protein required to generate polarized growth in fission yeast. J Cell Biol (2000) 1.49
Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10. Hum Genet (1988) 1.47
Genetics of the fission yeast Schizosaccharomyces pombe. Annu Rev Genet (1992) 1.47
Regulating S phase: CDKs, licensing and proteolysis. Cell (1996) 1.47
Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability. Mol Gen Genet (1994) 1.43
Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division. EMBO J (2001) 1.42
Molecular rearrangement of mating-type genes in fission yeast. Nature (1982) 1.41
Control of S-phase periodic transcription in the fission yeast mitotic cycle. EMBO J (1997) 1.40
The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins. J Cell Sci (1994) 1.39
In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis. J Cell Sci (2001) 1.38