Published in Biochemistry on June 14, 1977
A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. Proc Natl Acad Sci U S A (1996) 2.18
Multiple ribosomal RNA cleavage pathways in mammalian cells. Nucleic Acids Res (1981) 2.17
Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast. Mol Cell Biol (1997) 2.02
Large heterogeneous nuclear ribonucleic acid has three times as many 5' caps as polyadenylic acid segments, and most caps do not enter polyribosomes. Mol Cell Biol (1981) 1.97
Effect of undermethylation on mRNA cytoplasmic appearance and half-life. Mol Cell Biol (1984) 1.46
Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis. Cell Stress Chaperones (2013) 1.41
Molecular aspects of the in vivo and in vitro effects of ethionine, an analog of methionine. Microbiol Rev (1982) 1.30
S-adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin. Proc Natl Acad Sci U S A (1979) 1.29
Eukaryotic ribosomal RNA: the recent excitement in the nucleotide modification problem. Chromosoma (1997) 1.21
Fine structure of ribosomal RNA. II. Distribution of methylated sequences within Xenopus laevis rRNA. Nucleic Acids Res (1979) 1.13
Effects of adenovirus infection on rRNA synthesis and maturation in HeLa cells. Mol Cell Biol (1983) 1.11
Processing and migration of ribosomal ribonculeic acids in the nucleolus and nucleoplasm of rat liver nuclei. Biochem J (1978) 1.09
The Xenopus oocyte: a single-cell model for studying Ca2+ signaling. Cold Spring Harb Protoc (2013) 0.93
Non-coding RNA: what is functional and what is junk? Front Genet (2015) 0.92
Transimulation - protein biosynthesis web service. PLoS One (2013) 0.81
Growing an Embryo from a Single Cell: A Hurdle in Animal Life. Cold Spring Harb Perspect Biol (2015) 0.79
Proteomics sample preparation, preservation, and fractionation. Int J Proteomics (2012) 0.75
A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription. PLoS Genet (2017) 0.75
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science (1993) 19.80
AMINO ACID INCORPORATION INTO PROTEINS BY ESCHERICHIA COLI RIBOSOMES. Proc Natl Acad Sci U S A (1960) 11.02
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med (1991) 7.52
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci U S A (1993) 6.33
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n. Science (1991) 5.99
Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response. J Exp Med (1993) 5.71
Isolation of single-copy human genes from a library of yeast artificial chromosome clones. Science (1989) 5.29
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62
Fragile X genotype characterized by an unstable region of DNA. Science (1991) 4.33
Structure and organization of ribosomal DNA. Biochimie (1991) 4.31
The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. Nat Genet (2001) 4.15
Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism). Proc Natl Acad Sci U S A (1972) 4.09
Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med (1993) 4.04
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet (1996) 3.90
The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells. J Exp Med (1996) 3.82
PROTEIN SYNTHESIS IN ERYTHROID CELLS, I. RETICULOCYTE RIBOSOMES ACTIVE IN STIMULATING AMINO ACID INCORPORATION. Proc Natl Acad Sci U S A (1962) 3.81
Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation. Proc Natl Acad Sci U S A (1984) 3.53
Biosynthetic precursors of 30S and 50S ribosomal particles in Escherichia coli. Biochemistry (1968) 3.43
Mechanism and regulation of bacterial ribosomal RNA processing. Annu Rev Microbiol (1990) 3.37
Polyribosome metabolism in Escherichia coli. I. Extraction of polyribosomes and ribosomal subunits from fragile, growing Escherichia coli. J Mol Biol (1966) 3.29
Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells. J Immunol (1992) 3.15
Nucleolytic processing of ribonucleic acid transcripts in procaryotes. Microbiol Rev (1986) 2.70
Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. J Immunol (1994) 2.68
Locations and contexts of sequences that hybridize to poly(dG-dT).(dC-dA) in mammalian ribosomal DNAs and two X-linked genes. Nucleic Acids Res (1988) 2.64
X-linked situs abnormalities result from mutations in ZIC3. Nat Genet (1997) 2.62
Binding of adenosine 3':5'-cyclic phosphate to G factor of Escherichia coli, and its effects on GTPase, RNase V, and protein synthesis. Proc Natl Acad Sci U S A (1970) 2.49
Human Xq24-Xq28: approaches to mapping with yeast artificial chromosomes. Am J Hum Genet (1990) 2.45
Selection of sucrose-dependent Escherichia coli to obtain envelope mutants and fragile cultures. Science (1966) 2.43
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro. Science (1993) 2.35
Studies of X chromosome DNA methylation in normal human cells. Nature (1982) 2.34
Effects of IL-12 on the response and susceptibility to experimental viral infections. J Immunol (1994) 2.31
Amphotericin B potentiation of rifampicin as an antifungal agent against the yeast phase of Histoplasma capsulatum. Science (1972) 2.31
Genome-wide association scan for five major dimensions of personality. Mol Psychiatry (2008) 2.29
Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J Exp Med (1992) 2.26
Pathological consequences of sequence duplications in the human genome. Genome Res (1998) 2.26
Potentiation of the antifungal effects of antibiotics by amphotericin B. Antimicrob Agents Chemother (1972) 2.24
Multiple ribosomal RNA cleavage pathways in mammalian cells. Nucleic Acids Res (1981) 2.17
Synthesis of a large precursor to ribosomal RNA in a mutant of Escherichia coli. Proc Natl Acad Sci U S A (1973) 2.14
IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism. J Immunol (1995) 2.12
Effects of IL-12 on helper T cell-dependent immune responses in vivo. J Immunol (1994) 2.11
X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content. Genome Res (1997) 2.06
Interleukin 12 at the site of disease in tuberculosis. J Clin Invest (1994) 1.98
Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes. Nature (1985) 1.96
Meta-analysis of genome-wide association studies for personality. Mol Psychiatry (2010) 1.96
Isolation and characterization of cloned DNA sequences that hybridize to the human X chromosome. Cell (1980) 1.96
RNase III cleavage is obligate for maturation but not for function of Escherichia coli pre-23S rRNA. Proc Natl Acad Sci U S A (1984) 1.96
Interaction of plasma proteins and lipoproteins with amphotericin B. J Infect Dis (1984) 1.93
Synthesis and breakdown of ribonucleic acid in Escherichia coli starving for nitrogen. Biochim Biophys Acta (1966) 1.86
Characterization of a cloned DNA sequence that is present at centromeres of all human autosomes and the X chromosome and shows polymorphic variation. Proc Natl Acad Sci U S A (1984) 1.86
Coresistance to neomycin and kanamycin by mutations in an Escherichia coli locus that affects ribosomes. J Bacteriol (1968) 1.80
The formation and stabilization of 30S and 50S ribosome couples in Escherichia coli. Proc Natl Acad Sci U S A (1967) 1.79
Irreversible block of the mycelial-to-yeast phase transition of Histoplasma capsulatum. Science (1986) 1.78
Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis. Infect Immun (1996) 1.77
The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains. Proc Natl Acad Sci U S A (1997) 1.77
Location of the initial cleavage sites in mouse pre-rRNA. Mol Cell Biol (1983) 1.77
Loss of dispensable endonuclease activity in relief of polarity by suA. Nat New Biol (1971) 1.76
IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis. J Immunol (1994) 1.75
Mechanism of action of streptomycin in E. coli: interruption of the ribosome cycle at the initiation of protein synthesis. Proc Natl Acad Sci U S A (1968) 1.72
High neuroticism and low conscientiousness are associated with interleukin-6. Psychol Med (2009) 1.71
Classification of polyene antibiotics according to chemical structure and biological effects. Antimicrob Agents Chemother (1979) 1.69
Yeast artificial chromosomes with 200- to 800-kilobase inserts of human DNA containing HLA, V kappa, 5S, and Xq24-Xq28 sequences. Proc Natl Acad Sci U S A (1989) 1.66
S1 nuclease mapping analysis of ribosomal RNA processing in wild type and processing deficient Escherichia coli. J Biol Chem (1983) 1.66
IL-12 regulates T helper type 1 cytokine responses in human infectious disease. J Immunol (1994) 1.65
Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. Hum Mol Genet (1996) 1.65
Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res (1994) 1.64
Derepression with decreased expression of the G6PD locus on the inactive X chromosome in normal human cells. Cell (1982) 1.62
Involvement of oxidative damage in erythrocyte lysis induced by amphotericin B. Antimicrob Agents Chemother (1985) 1.62
IL-12 induces IFN-gamma expression and secretion in mouse peritoneal macrophages. J Immunol (1997) 1.61
Characterization of the binding of amphotericin B to Saccharomyces cerevisiae and relationship to the antifungal effects. Antimicrob Agents Chemother (1974) 1.60
Polyribosome metabolism in Escherichia coli treated with chloramphenicol, neomycin, spectinomycin or tetracycline. J Mol Biol (1969) 1.55
Coregulation of processing and translation: mature 5' termini of Escherichia coli 23S ribosomal RNA form in polysomes. Proc Natl Acad Sci U S A (1988) 1.54
Incomplete X chromosome dosage compensation in chorionic villi of human placenta. Proc Natl Acad Sci U S A (1985) 1.53
Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci U S A (1994) 1.53
Turnover of protein in Escherichia coli starving for nitrogen. Biochim Biophys Acta (1966) 1.52
Synergistic effect of amphotericin B and 1,3-bis(2-chloroethyl)-1-nitrosourea against a transplantable AKR leukemia. Cancer Res (1974) 1.52
The human HPRT gene on a yeast artificial chromosome is functional when transferred to mouse cells by cell fusion. Genomics (1991) 1.49
The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6. Blood (1988) 1.47
RNA metabolism during morphogenesis in Histoplasma capsulatum. J Gen Microbiol (1974) 1.45
Regulation of dimorphism in the pathogenic fungus Histoplasma capsulatum. Nature (1977) 1.44
IL-12, as an adjuvant, promotes a T helper 1 cell, but does not suppress a T helper 2 cell recall response. J Immunol (1996) 1.42
Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3' CpG clusters: implications for X chromosome dosage compensation. Nucleic Acids Res (1984) 1.42
IL-12 inhibits the production of IL-4 and IL-10 in allergen-specific human CD4+ T lymphocytes. J Immunol (1995) 1.40
Frequent silencing of the GPC3 gene in ovarian cancer cell lines. Cancer Res (1999) 1.40
Mutants in Escherichia coli ribosomes: a new selection. Proc Natl Acad Sci U S A (1969) 1.40
Saccharomyces cerevisiae: sorbitol-dependent fragile mutants. Biochem Biophys Res Commun (1974) 1.39
Coupling of rates of transcription, translation, and messenger ribonucleic acid degradation in streptomycin-dependent mutants of Escherichia coli. J Bacteriol (1976) 1.37
Yeast artificial chromosomes containing human Xq24-Xq28 DNA: library construction and representation of probe sequences. Genomics (1990) 1.35
G factor mutants of Escherichia coli: map location and properties. Biochem Biophys Res Commun (1971) 1.35
Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region. Hum Mol Genet (2000) 1.34
Exoribonucleases in wild type Escherichia coli and RNase II-deficient mutants. J Biol Chem (1977) 1.33
The assessment of antimicrobial combinations. Rev Infect Dis (1981) 1.33
Enhancing effect of natural killer cell stimulatory factor (NKSF/interleukin-12) on cell-mediated cytotoxicity against tumor-derived and virus-infected cells. Eur J Immunol (1993) 1.32
Stability of amphotericin B in fungal culture media. Antimicrob Agents Chemother (1975) 1.31
Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J Immunol (1993) 1.31
Ordered processing of Escherichia coli 23S rRNA in vitro. Nucleic Acids Res (1985) 1.31
Glypican-3 expression in Wilms tumor and hepatoblastoma. J Pediatr Hematol Oncol (2001) 1.30
Mapping human chromosomes by walking with sequence-tagged sites from end fragments of yeast artificial chromosome inserts. Genomics (1992) 1.30
Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells. Hum Mol Genet (1999) 1.29
Translation: its mechanism and control. Science (1972) 1.29
Transcription and processing of RNA from mouse ribosomal DNA transfected into hamster cells. Mol Cell Biol (1989) 1.27