PubRank

G Tiegs

Author PubWeight™ 45.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J Immunol 1994 2.87
2 Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 1995 2.55
3 Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology 1996 2.27
4 Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 1995 2.21
5 Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-alpha. J Immunol 1992 1.60
6 In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. Eur J Immunol 1997 1.53
7 A novel technique for selective NF-kappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. Gut 2009 1.49
8 Importance of Kupffer cells for T-cell-dependent liver injury in mice. Am J Pathol 2000 1.42
9 A novel biologically active seleno-organic compound--II. Activity of PZ 51 in relation to glutathione peroxidase. Biochem Pharmacol 1984 1.34
10 Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology 1998 1.28
11 The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure. Mol Med 1996 1.16
12 Acute hepatotoxicity of Pseudomonas aeruginosa exotoxin A in mice depends on T cells and TNF. J Immunol 1998 1.13
13 Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-alpha. Eur J Immunol 1995 1.13
14 TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis. J Immunol 2001 1.13
15 Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice. J Clin Invest 2001 1.12
16 Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice. Hepatology 1996 1.12
17 DNA fragmentation in mouse organs during endotoxic shock. Am J Pathol 1996 1.10
18 The multiple functions of heme oxygenase-1 in the liver. Z Gastroenterol 2012 1.06
19 Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation. Hepatology 1999 1.05
20 Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice. Gastroenterology 1995 1.04
21 Pathophysiological mechanisms of TNF during intoxication with natural or man-made toxins. Toxicology 1999 0.99
22 Concanavalin A-induced liver injury triggers hepatocyte proliferation. J Clin Invest 1998 0.98
23 Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure. J Immunol 2001 0.95
24 Low-molecular-weight hyaluronic acid induces nuclear factor-kappaB-dependent resistance against tumor necrosis factor alpha-mediated liver injury in mice. Hepatology 2001 0.93
25 T cell stimulus-induced crosstalk between lymphocytes and liver macrophages results in augmented cytokine release. Exp Cell Res 1996 0.92
26 A novel biologically active seleno-organic compound--V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase. Biochem Pharmacol 1985 0.91
27 Leukotriene D4 mediates galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol 1987 0.89
28 In vivo evidence for protease-catalysed mechanism providing bioactive tumor necrosis factor alpha. Biochem Pharmacol 1990 0.89
29 Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways. Hepatology 1995 0.89
30 Pre-apoptotic alterations in hepatocytes of TNFalpha-treated galactosamine-sensitized mice. J Histochem Cytochem 1998 0.89
31 Evidence for the involvement of a reperfusion injury in galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol 1987 0.88
32 A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice. Biochem Pharmacol 1986 0.87
33 TNF tolerance and cytotoxicity in the liver: the role of interleukin-1beta, inducible nitric oxide-synthase and heme oxygenase-1 in D-galactosamine-sensitized mice. Inflamm Res 2002 0.87
34 Protection from T cell-mediated murine liver failure by phosphodiesterase inhibitors. J Pharmacol Exp Ther 1997 0.86
35 Synergism of Pseudomonas aeruginosa exotoxin A with endotoxin, superantigen, or TNF results in TNFR1- and TNFR2-dependent liver toxicity in mice. Immunol Lett 2000 0.85
36 Chronic inflammation and protection from acute hepatitis in transgenic mice expressing TNF in endothelial cells. J Immunol 2001 0.84
37 Immunomodulating properties of the antibiotic novobiocin in human monocytes. Antimicrob Agents Chemother 1998 0.80
38 Tolerance against tumor necrosis factor alpha (TNF)-induced hepatotoxicity in mice: the role of nitric oxide. Toxicol Lett 1995 0.77
39 The role of leukotriene D4 in septic shock models. Eicosanoids 1992 0.76
40 [Hepatology: from basic science to the clinic]. Z Gastroenterol 2012 0.75
41 Inhibition by ebselen of microsomal NADPH-cytochrome P450-reductase in vitro but not in vivo. Biochem Pharmacol 1986 0.75
42 Quantification of apoptotic and lytic cell death by video microscopy in combination with artificial neural networks. Cytometry 1998 0.75
43 Ebselen--an in vivo immune response modifier. Biomed Environ Sci 1997 0.75
44 Protection by ebselen against endotoxin shock in rats or mice sensitized by galactosamine. Prog Clin Biol Res 1987 0.75
45 Ultrastructural alterations of mitochondria in pre-apoptotic and apoptotic hepatocytes of TNF alpha-treated galactosamine-sensitized mice. Ann N Y Acad Sci 1999 0.75
46 Modulation of glyceraldehyde-3-phosphate dehydrogenase in Salmonella abortus equi lipopolysaccharide-treated mice. Eur J Pharmacol 1994 0.75