Published in Methods Enzymol on January 01, 1996
Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev (2000) 9.36
Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation. EMBO J (1998) 2.04
A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties. Antimicrob Agents Chemother (2004) 1.94
Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure. Mol Cell Biol (1999) 1.79
Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID. Proc Natl Acad Sci U S A (1999) 1.77
V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins. J Exp Med (1997) 1.59
Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase. EMBO J (1998) 1.52
A dynamic model for PC4 coactivator function in RNA polymerase II transcription. Proc Natl Acad Sci U S A (1998) 1.47
Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells. Proc Natl Acad Sci U S A (1999) 1.44
Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split. Mol Cell Biol (2001) 1.38
UPA, a universal protein array system for quantitative detection of protein-protein, protein-DNA, protein-RNA and protein-ligand interactions. Nucleic Acids Res (2000) 1.37
MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery. Nucleic Acids Res (2000) 1.34
TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4. Mol Cell Biol (2002) 1.31
Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors. Mol Cell Biol (2004) 1.31
A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. Proc Natl Acad Sci U S A (2000) 1.26
Mechanism of synergy between TATA and initiator: synergistic binding of TFIID following a putative TFIIA-induced isomerization. Genes Dev (1997) 1.21
Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex. Mol Cell Biol (1998) 1.21
The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol (2004) 1.19
TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4. EMBO J (1998) 1.17
The new core promoter element XCPE1 (X Core Promoter Element 1) directs activator-, mediator-, and TATA-binding protein-dependent but TFIID-independent RNA polymerase II transcription from TATA-less promoters. Mol Cell Biol (2007) 1.11
Core promoter-dependent TFIIB conformation and a role for TFIIB conformation in transcription start site selection. Mol Cell Biol (2002) 1.06
Architectural specificity in chromatin structure at the TATA box in vivo: nucleosome displacement upon beta-phaseolin gene activation. Proc Natl Acad Sci U S A (1998) 1.05
V(D)J recombination: in vitro coding joint formation. Mol Cell Biol (1997) 1.00
Coactivation by OCA-B: definition of critical regions and synergism with general cofactors. Mol Cell Biol (1998) 0.97
The acidic C-terminal domain and A-box of HMGB-1 regulates p53-mediated transcription. Nucleic Acids Res (2003) 0.96
Different functional modes of p300 in activation of RNA polymerase III transcription from chromatin templates. Mol Cell Biol (2008) 0.96
Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery. Mol Cell Biol (2009) 0.92
A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment. Mol Cell Biol (2004) 0.91
Nucleosomal H2B ubiquitylation with purified factors. Methods (2011) 0.81
The Sub1 nuclear protein protects DNA from oxidative damage. Mol Cell Biochem (2015) 0.75
TFIIB is only ∼9 Å away from the 5'-end of a trimeric RNA primer in a functional RNA polymerase II preinitiation complex. PLoS One (2015) 0.75
A Transcription Factor IIA Binding Site Differentially Regulates RNA Polymerase II-Mediated Transcription in a Promoter Context-dependent Manner. J Biol Chem (2017) 0.75
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell (1985) 13.36
Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. J Biol Chem (1979) 11.68
Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes. Cell (1980) 10.87
Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. J Biol Chem (1980) 10.78
Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. J Biol Chem (1980) 10.63
Eukaryotic gene transcription with purified components. Methods Enzymol (1983) 9.71
Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system. Cell (1980) 8.02
Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell (1980) 7.42
Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol (1981) 7.12
Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol Cell Biol (1983) 7.01
Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature (1969) 6.98
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A (1985) 6.94
The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88
Transcription of class III genes: formation of preinitiation complexes. Science (1983) 6.79
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A (1982) 6.57
Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (1970) 6.39
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol (1988) 5.60
Biochemistry and structural biology of transcription factor IID (TFIID). Annu Rev Biochem (1996) 5.19
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell (1987) 5.04
Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature (1995) 4.93
Crystal structure of TFIID TATA-box binding protein. Nature (1992) 4.85
A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc Natl Acad Sci U S A (1988) 4.72
Specific nucleolar and nucleoplasmic RNA polymerases. Proc Natl Acad Sci U S A (1970) 4.63
Synergistic activation of transcription by CBP and p53. Nature (1997) 4.54
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A (1988) 4.33
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell (1984) 4.32
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell (1988) 4.15
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature (1991) 4.09
Inducible binding of a factor to the c-fos enhancer. Cell (1986) 3.98
Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem (1988) 3.96
A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature (1988) 3.95
Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J Biol Chem (1985) 3.89
Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. J Biol Chem (1974) 3.84
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Proc Natl Acad Sci U S A (1986) 3.81
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature (1989) 3.74
Structure and function of the b/HLH/Z domain of USF. EMBO J (1994) 3.70
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci U S A (1996) 3.61
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol (1987) 3.52
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science (1995) 3.50
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res (1991) 3.48
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell (1999) 3.47
The structure of the human histone genes: clustered but not tandemly repeated. Cell (1981) 3.47
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell (1994) 3.43
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature (1990) 3.42
Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. Science (1988) 3.40
Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE. J Biol Chem (1987) 3.38
Activation of class II gene transcription by regulatory factors is potentiated by a novel activity. Cell (1991) 3.36
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol (2001) 3.31
Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus. Cell (1985) 3.21
Family of proteins that interact with TFIID and regulate promoter activity. Cell (1991) 3.20
Mechanism of action of a yeast activator: direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions. Cell (1988) 3.17
The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell (1981) 3.15
Role of DNA-dependent RNA polymerase 3 in the transcription of the tRNA and 5S RNA genes. Proc Natl Acad Sci U S A (1974) 3.14
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem Sci (2000) 3.03
Genetic diversity and relationships among isolates of Rhizobium leguminosarum biovar phaseoli. Appl Environ Microbiol (1988) 2.98
Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta. Nature (1995) 2.96
Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection. Proc Natl Acad Sci U S A (1974) 2.95
Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. J Biol Chem (1987) 2.95
Formation of a rate-limiting intermediate in 5S RNA gene transcription. Cell (1985) 2.94
Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature (1996) 2.92
Direct interaction of human TFIID with the HIV-1 transactivator tat. Nature (1994) 2.87
Activation of transcription factor IIIC by the adenovirus E1A protein. Cell (1988) 2.86
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev (1992) 2.85
Multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in Xenopus laevis. Isolation and partial characterization. J Biol Chem (1974) 2.80
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc Natl Acad Sci U S A (1998) 2.76
Multiple factors involved in the transcription of class III genes in Xenopus laevis. J Biol Chem (1982) 2.75
Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol Cell Biol (1995) 2.74
Microstructure and mechanical behavior of Ti-6Al-4V produced by rapid-layer manufacturing, for biomedical applications. J Mech Behav Biomed Mater (2008) 2.72
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol Cell (1999) 2.71
Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A (1988) 2.70
Probiotics for treating infectious diarrhoea. Cochrane Database Syst Rev (2004) 2.70
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Mol Cell Biol (1986) 2.69
HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol Cell (2000) 2.68
Purification of the c-fos enhancer-binding protein. Mol Cell Biol (1987) 2.64
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes Dev (1988) 2.60
Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature (1996) 2.58
Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation. Cell (1980) 2.58
Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. EMBO J (1993) 2.56
The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature (1993) 2.50
Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes Dev (1988) 2.47
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol Cell Biol (1992) 2.47
Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes Dev (1996) 2.45
Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J (1993) 2.45
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell (1992) 2.43
Transcripts of the adeno-associated virus genome: mapping of the major RNAs. J Virol (1980) 2.42
A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID. J Biol Chem (1998) 2.40
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Mol Cell (2000) 2.39
Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Mol Cell Biol (1984) 2.38
Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes. Mol Cell Biol (1995) 2.33
Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infection. Cell (1976) 2.33
Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (1988) 2.31