Published in Mol Cell Biol on October 01, 1987
Compilation of transcription regulating proteins. Nucleic Acids Res (1988) 9.71
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J (1990) 4.28
ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J (1995) 3.86
UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol Cell Biol (1989) 3.83
Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol Cell Biol (2003) 2.73
Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A (1988) 2.70
Purification of the c-fos enhancer-binding protein. Mol Cell Biol (1987) 2.64
Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene. Mol Cell Biol (1990) 2.41
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol (1988) 2.40
Autoregulation of fos: the dyad symmetry element as the major target of repression. EMBO J (1989) 2.37
Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines. Mol Cell Biol (1990) 2.34
Activation of the human "beta 2-interferon/hepatocyte-stimulating factor/interleukin 6" promoter by cytokines, viruses, and second messenger agonists. Proc Natl Acad Sci U S A (1988) 2.32
Spatial flexibility in ternary complexes between SRF and its accessory proteins. EMBO J (1992) 2.28
Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter. Mol Cell Biol (1989) 2.20
A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol Cell Biol (1993) 2.15
Inhibition of v-raf-dependent c-fos expression and transformation by a kinase-defective mutant of the mitogen-activated protein kinase Erk2. Mol Cell Biol (1994) 2.08
Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. EMBO J (2007) 2.07
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1991) 2.04
Two distinct cellular phosphoproteins bind to the c-fos serum response element. EMBO J (1989) 2.03
Interferon-gamma-induced transcriptional activation is mediated by protein kinase C. Proc Natl Acad Sci U S A (1988) 1.97
Interaction of ATF6 and serum response factor. Mol Cell Biol (1997) 1.96
Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes. Mol Cell Biol (1989) 1.94
Regulatory role of MEF2D in serum induction of the c-jun promoter. Mol Cell Biol (1995) 1.93
Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs. Mol Cell Biol (1993) 1.79
Functional serum response elements upstream of the growth factor-inducible gene zif268. Mol Cell Biol (1989) 1.78
Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos. Mol Cell Biol (1989) 1.78
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Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol Cell Biol (1994) 1.73
A multiple cytokine- and second messenger-responsive element in the enhancer of the human interleukin-6 gene: similarities with c-fos gene regulation. Mol Cell Biol (1989) 1.70
Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor. Mol Cell Biol (1996) 1.64
Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat. Mol Cell Biol (1989) 1.63
Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activation. Proc Natl Acad Sci U S A (1988) 1.60
Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways. Mol Cell Biol (1989) 1.59
The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts. Mol Cell Biol (1991) 1.54
Fos C-terminal mutations block down-regulation of c-fos transcription following serum stimulation. EMBO J (1988) 1.54
Mapping of epidermal growth factor-, serum-, and phorbol ester-responsive sequence elements in the c-jun promoter. Mol Cell Biol (1992) 1.49
An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate. Mol Cell Biol (1989) 1.45
Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties. EMBO J (1992) 1.44
Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activities. Mol Cell Biol (1991) 1.41
Multiple basal promoter elements determine the level of human c-fos transcription. Mol Cell Biol (1991) 1.40
Mutation of serum response factor phosphorylation sites and the mechanism by which its DNA-binding activity is increased by casein kinase II. Mol Cell Biol (1991) 1.39
Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16. Proc Natl Acad Sci U S A (1993) 1.33
In vitro squelching of activated transcription by serum response factor: evidence for a common coactivator used by multiple transcriptional activators. Nucleic Acids Res (1992) 1.33
Binding of NCK to SOS and activation of ras-dependent gene expression. Mol Cell Biol (1995) 1.30
Fos and jun cooperate in transcriptional regulation via heterologous activation domains. Mol Cell Biol (1990) 1.30
Cell-type specific multiprotein complex formation over the c-fos serum response element in vivo: ternary complex formation is not required for the induction of c-fos. Nucleic Acids Res (1991) 1.28
p67SRF is a constitutive nuclear protein implicated in the modulation of genes required throughout the G1 period. Cell Regul (1991) 1.28
Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. Mol Cell Biol (1992) 1.27
Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax. J Virol (1989) 1.22
Heterodimers of myogenic helix-loop-helix regulatory factors and E12 bind a complex element governing myogenic induction of the avian cardiac alpha-actin promoter. Mol Cell Biol (1991) 1.22
Regulation of the human beta-actin promoter by upstream and intron domains. Nucleic Acids Res (1989) 1.21
The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts. Mol Cell Biol (1991) 1.21
c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1. Mol Cell Biol (1991) 1.20
Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein. Nucleic Acids Res (1992) 1.19
Utp14b: a unique retrogene within a gene that has acquired multiple promoters and a specific function in spermatogenesis. Dev Biol (2007) 1.14
ras-induced c-fos expression and proliferation in living rat fibroblasts involves C-kinase activation and the serum response element pathway. EMBO J (1990) 1.14
Repression of the basal c-fos promoter by wild-type p53. Nucleic Acids Res (1992) 1.13
The same target sequences are differentially important for activation of the interleukin 2 receptor alpha-chain gene in two distinct T-cell lines. Proc Natl Acad Sci U S A (1990) 1.13
Overexpression of an Aplysia shaker K+ channel gene modifies the electrical properties and synaptic efficacy of identified Aplysia neurons. Proc Natl Acad Sci U S A (1992) 1.10
E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence. Proc Natl Acad Sci U S A (1990) 1.08
Casein kinase II induces c-fos expression via the serum response element pathway and p67SRF phosphorylation in living fibroblasts. EMBO J (1991) 1.08
Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J (1990) 1.06
Goals for signal transduction pathways: linking up with transcriptional regulation. EMBO J (1994) 1.03
Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen. J Virol (1994) 1.02
Signal transduction convergence: phorbol esters and insulin inhibit phosphoenolpyruvate carboxykinase gene transcription through the same 10-base-pair sequence. Proc Natl Acad Sci U S A (1991) 1.02
Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes. Proc Natl Acad Sci U S A (1988) 1.02
N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma. EMBO J (1991) 1.01
Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation. J Virol (1992) 1.00
The distribution of SNPs in human gene regulatory regions. BMC Genomics (2005) 1.00
Functional analysis of an isolated fos promoter element with AP-1 site homology reveals cell type-specific transcriptional properties. Mol Cell Biol (1990) 0.99
Regulation of c-fos and c-jun protooncogene expression by the Ca(2+)-ATPase inhibitor thapsigargin. Proc Natl Acad Sci U S A (1991) 0.98
Regulation of the cfos serum response element by C/EBPbeta. Mol Cell Biol (1997) 0.97
Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene. J Clin Invest (1993) 0.96
Multiple interdependent regulatory sites in the mouse c-fos promoter determine basal level transcription: cell type-specific effects. Nucleic Acids Res (1991) 0.95
Maximal serum stimulation of the c-fos serum response element requires both the serum response factor and a novel binding factor, SRE-binding protein. Mol Cell Biol (1992) 0.95
Identification of a coactivator that increases activation of transcription by serum response factor and GAL4-VP16 in vitro. Proc Natl Acad Sci U S A (1992) 0.94
The trk family of receptors mediates nerve growth factor and neurotrophin-3 effects in melanocytes. J Clin Invest (1994) 0.94
The c-fos cyclic AMP-responsive element conveys constitutive expression to a tissue-specific promoter. Mol Cell Biol (1990) 0.93
A new cAMP response element in the transcribed region of the human c-fos gene. Nucleic Acids Res (1991) 0.92
Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging. Mol Cell Biol (1994) 0.90
Identification of a multiprotein complex interacting with the c-fos serum response element. Mol Cell Biol (1991) 0.89
Genomic organization and chromosomal localization of the mouse synexin gene. Biochem J (1994) 0.89
Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A. Mol Cell Biol (1995) 0.88
Voltage-insensitive Ca2+ channels and Ca2+/calmodulin-dependent protein kinases propagate signals from endothelin-1 receptors to the c-fos promoter. Mol Cell Biol (1996) 0.87
Conserved region of the rat alpha-lactalbumin promoter is a target site for protein binding in vitro. Biochem J (1988) 0.85
Dual modes of control of c-fos mRNA induction by intracellular calcium in T cells. Mol Cell Biol (1994) 0.84
Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surface. J Biol Chem (2015) 0.83
Involvement of second messengers in regulation of the low-density lipoprotein receptor gene. Mol Cell Biol (1989) 0.83
Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor. Mol Cell Biol (1994) 0.82
Altered transcriptional activity of c-fos promoter plasmids in v-raf-transformed NIH 3T3 cells. Mol Cell Biol (1990) 0.81
High-throughput functional comparison of promoter and enhancer activities. Genome Res (2016) 0.80
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells. Biochem J (1992) 0.80
Neonatal induction of a nuclear protein that binds to the c-fos enhancer. Proc Natl Acad Sci U S A (1989) 0.80
Regulation of gene expression in PC12 cells via an activator of dual second messengers: pituitary adenylate cyclase activating polypeptide. Mol Biol Cell (1992) 0.77
Characterization of two independent mechanisms by which interferon-induced gene expression is down regulated. Cell Regul (1990) 0.77
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Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell (1986) 9.10
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