Published in Cell on December 05, 1986
Sequence-specific interactions of a pea nuclear factor with light-responsive elements upstream of the rbcS-3A gene. EMBO J (1987) 6.06
Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J (1987) 4.68
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J (1990) 4.28
UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein. Mol Cell Biol (1989) 3.83
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci U S A (1988) 3.83
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol (1987) 3.52
Purification and characterization of human mitochondrial transcription factor 1. Mol Cell Biol (1988) 2.78
Selective transcription in response to an inflammatory stimulus. Cell (2010) 2.75
Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells. Proc Natl Acad Sci U S A (1989) 2.74
Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A (1988) 2.70
Purification of the c-fos enhancer-binding protein. Mol Cell Biol (1987) 2.64
Journey to the surface of the cell: Fos regulation and the SRE. EMBO J (1995) 2.43
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol (1988) 2.40
Alignment of U3 region sequences of mammalian type C viruses: identification of highly conserved motifs and implications for enhancer design. J Virol (1990) 2.34
Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription. Mol Cell Biol (1996) 2.32
Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes. J Clin Invest (1988) 2.29
Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter. Mol Cell Biol (1989) 2.20
A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol Cell Biol (1993) 2.15
Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase. Proc Natl Acad Sci U S A (1993) 2.12
Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element. Nucleic Acids Res (1987) 2.09
Two distinct cellular phosphoproteins bind to the c-fos serum response element. EMBO J (1989) 2.03
Identification of an inducible factor that binds to a positive regulatory element of the human beta-interferon gene. Proc Natl Acad Sci U S A (1988) 2.01
Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes. Mol Cell Biol (1989) 1.94
Regulatory role of MEF2D in serum induction of the c-jun promoter. Mol Cell Biol (1995) 1.93
Alterations in binding characteristics of the human immunodeficiency virus enhancer factor. J Virol (1988) 1.88
Overlapping sites for constitutive and induced DNA binding factors involved in interferon-stimulated transcription. EMBO J (1989) 1.87
The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes. Mol Cell Biol (1991) 1.82
Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs. Mol Cell Biol (1993) 1.79
Structural organization of the human alpha-galactosidase A gene: further evidence for the absence of a 3' untranslated region. Proc Natl Acad Sci U S A (1988) 1.79
Functional serum response elements upstream of the growth factor-inducible gene zif268. Mol Cell Biol (1989) 1.78
Point mutational analysis of the human c-fos serum response factor binding site. Nucleic Acids Res (1989) 1.76
Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate-inducible element. J Virol (1990) 1.74
Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor. Mol Cell Biol (1994) 1.73
Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts. Proc Natl Acad Sci U S A (1988) 1.67
Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent. BMC Mol Biol (2004) 1.66
Casein kinase II phosphorylation increases the rate of serum response factor-binding site exchange. EMBO J (1992) 1.60
ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun. Mol Cell Biol (1989) 1.59
Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways. Mol Cell Biol (1989) 1.59
Binding of multiple nuclear factors to the 5' upstream regulatory element of the murine major histocompatibility class I gene. Mol Cell Biol (1987) 1.59
Mapping of epidermal growth factor-, serum-, and phorbol ester-responsive sequence elements in the c-jun promoter. Mol Cell Biol (1992) 1.49
A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1. Mol Cell Biol (1995) 1.49
Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction. Mol Cell Biol (1989) 1.49
Transcriptional stimulation by CaPO4-DNA precipitates. Nucleic Acids Res (1988) 1.47
Cell-cycle-specific interaction of nuclear DNA-binding proteins with a CCAAT sequence from the human thymidine kinase gene. Proc Natl Acad Sci U S A (1987) 1.45
The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction. Mol Cell Biol (1993) 1.45
YY1 facilitates the association of serum response factor with the c-fos serum response element. Mol Cell Biol (1995) 1.42
Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription. Proc Natl Acad Sci U S A (1990) 1.39
Mutation of serum response factor phosphorylation sites and the mechanism by which its DNA-binding activity is increased by casein kinase II. Mol Cell Biol (1991) 1.39
Nuclear proteins from lactating mammary glands bind to the promoter of a milk protein gene. Nucleic Acids Res (1987) 1.37
Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function. EMBO J (1988) 1.33
In vitro squelching of activated transcription by serum response factor: evidence for a common coactivator used by multiple transcriptional activators. Nucleic Acids Res (1992) 1.33
Epidermal growth factor induction of the c-jun promoter by a Rac pathway. Mol Cell Biol (1998) 1.30
The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene. Mol Cell Biol (1987) 1.28
Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. Mol Cell Biol (1992) 1.27
Ionizing radiation activates transcription of the EGR1 gene via CArG elements. Proc Natl Acad Sci U S A (1992) 1.25
Three sequence-specific DNA-protein complexes are formed with the same promoter element essential for expression of the rat somatostatin gene. Mol Cell Biol (1988) 1.24
p53 in chronic myelogenous leukemia. Study of mechanisms of differential expression. J Exp Med (1988) 1.24
c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain. Proc Natl Acad Sci U S A (1992) 1.23
The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts. Mol Cell Biol (1991) 1.21
Regulation of the human beta-actin promoter by upstream and intron domains. Nucleic Acids Res (1989) 1.21
Inhibition of c-fos transcription and phosphorylation of the serum response factor by an inhibitor of phospholipase C-type reactions. Mol Cell Biol (1990) 1.17
Transcriptional and posttranscriptional control of c-fos gene expression in human monocytes. Mol Cell Biol (1988) 1.15
ras-induced c-fos expression and proliferation in living rat fibroblasts involves C-kinase activation and the serum response element pathway. EMBO J (1990) 1.14
The same target sequences are differentially important for activation of the interleukin 2 receptor alpha-chain gene in two distinct T-cell lines. Proc Natl Acad Sci U S A (1990) 1.13
Characterization of the rat transforming growth factor alpha gene and identification of promoter sequences. Mol Cell Biol (1990) 1.13
A novel 7-nucleotide motif located in 3' untranslated sequences of the immediate-early gene set mediates platelet-derived growth factor induction of the JE gene. Mol Cell Biol (1992) 1.11
A GC-rich element confers epidermal growth factor responsiveness to transcription from the gastrin promoter. Mol Cell Biol (1991) 1.11
Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites. Mol Cell Biol (1989) 1.10
Interaction between NF-kappa B- and serum response factor-binding elements activates an interleukin-2 receptor alpha-chain enhancer specifically in T lymphocytes. Mol Cell Biol (1993) 1.09
Casein kinase II induces c-fos expression via the serum response element pathway and p67SRF phosphorylation in living fibroblasts. EMBO J (1991) 1.08
Lipopolysaccharide-induced NF-kappa B activation in mouse 70Z/3 pre-B lymphocytes is inhibited by mevinolin and 5'-methylthioadenosine: roles of protein isoprenylation and carboxyl methylation reactions. Mol Cell Biol (1992) 1.07
fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element. Mol Cell Biol (1993) 1.04
Nerve growth factor regulates gene expression by several distinct mechanisms. Mol Cell Biol (1989) 1.03
Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes. Proc Natl Acad Sci U S A (1988) 1.02
N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma. EMBO J (1991) 1.01
Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation. Mol Cell Biol (1995) 1.00
Functional analysis of an isolated fos promoter element with AP-1 site homology reveals cell type-specific transcriptional properties. Mol Cell Biol (1990) 0.99
Transcriptional antagonist cAMP-responsive element modulator (CREM) down-regulates c-fos cAMP-induced expression. Proc Natl Acad Sci U S A (1991) 0.98
Differential regulation of NFAT and SRF by the B cell receptor via a PLCgamma-Ca(2+)-dependent pathway. EMBO J (2003) 0.97
Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins. J Cell Biol (1991) 0.97
A new genetic approach for studying hormonal regulation of urokinase-type plasminogen activator gene expression in LLC-PK1 cells. Mol Cell Biol (1987) 0.96
Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene. J Clin Invest (1993) 0.96
S-phase-specific transcription regulatory elements are present in a replication-independent testis-specific H2B histone gene. Mol Cell Biol (1989) 0.96
Maximal serum stimulation of the c-fos serum response element requires both the serum response factor and a novel binding factor, SRE-binding protein. Mol Cell Biol (1992) 0.95
Multiple interdependent regulatory sites in the mouse c-fos promoter determine basal level transcription: cell type-specific effects. Nucleic Acids Res (1991) 0.95
Identification of a coactivator that increases activation of transcription by serum response factor and GAL4-VP16 in vitro. Proc Natl Acad Sci U S A (1992) 0.94
Identification of a multiprotein complex interacting with the c-fos serum response element. Mol Cell Biol (1991) 0.89
DNA curvature in front of the human mitochondrial L-strand replication origin with specific protein binding. Nucleic Acids Res (1989) 0.89
Response modification in carcinogenesis. Environ Health Perspect (1989) 0.86
Conserved region of the rat alpha-lactalbumin promoter is a target site for protein binding in vitro. Biochem J (1988) 0.85
Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells. Mol Cell Biol (1990) 0.85
Chemoattractant-induced activation of c-fos gene expression in human monocytes. J Exp Med (1987) 0.83
Regulation of collagenase gene expression by okadaic acid, an inhibitor of protein phosphatases. Cell Regul (1990) 0.81
Dual functions of a cis-acting element within the rat prolactin gene promoter. Mol Cell Biol (1989) 0.80
Neonatal induction of a nuclear protein that binds to the c-fos enhancer. Proc Natl Acad Sci U S A (1989) 0.80
c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells. Mol Cell Biol (1990) 0.79
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79
Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell (1985) 13.36
Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. J Biol Chem (1979) 11.68
Wild-type p53 activates transcription in vitro. Nature (1992) 11.39
Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes. Cell (1980) 10.87
Multiple factors required for accurate initiation of transcription by purified RNA polymerase II. J Biol Chem (1980) 10.78
Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III. J Biol Chem (1980) 10.63
Eukaryotic gene transcription with purified components. Methods Enzymol (1983) 9.71
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell (2000) 9.13
Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system. Cell (1980) 8.02
Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell (1980) 7.42
Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol (1981) 7.12
Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Mol Cell Biol (1983) 7.01
Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms. Nature (1969) 6.98
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A (1985) 6.94
The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. Genes Dev (1990) 6.88
Transcription of class III genes: formation of preinitiation complexes. Science (1983) 6.79
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A (1982) 6.57
Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (1970) 6.39
Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID. Mol Cell Biol (1988) 5.60
Biochemistry and structural biology of transcription factor IID (TFIID). Annu Rev Biochem (1996) 5.19
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell (1987) 5.04
Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature (1995) 4.93
Crystal structure of TFIID TATA-box binding protein. Nature (1992) 4.85
A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc Natl Acad Sci U S A (1988) 4.72
Specific nucleolar and nucleoplasmic RNA polymerases. Proc Natl Acad Sci U S A (1970) 4.63
Synergistic activation of transcription by CBP and p53. Nature (1997) 4.54
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J Biol Chem (2000) 4.37
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A (1988) 4.33
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell (1984) 4.32
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell (1988) 4.15
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature (1991) 4.09
Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei. J Biol Chem (1988) 3.96
A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein. Nature (1988) 3.95
Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II. J Biol Chem (1985) 3.89
Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. J Biol Chem (1974) 3.84
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Proc Natl Acad Sci U S A (1986) 3.81
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box. Nature (1989) 3.74
Structure and function of the b/HLH/Z domain of USF. EMBO J (1994) 3.70
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci U S A (1996) 3.61
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore. Mol Cell Biol (1987) 3.52
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators. Science (1995) 3.50
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res (1991) 3.48
Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell (1999) 3.47
The structure of the human histone genes: clustered but not tandemly repeated. Cell (1981) 3.47
Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell (1994) 3.43
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Physical analysis of transcription preinitiation complex assembly on a class II gene promoter. Science (1988) 3.40
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Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol (2001) 3.31
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Family of proteins that interact with TFIID and regulate promoter activity. Cell (1991) 3.20
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Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract. J Biol Chem (1987) 2.95
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Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. Nature (1996) 2.92
Direct interaction of human TFIID with the HIV-1 transactivator tat. Nature (1994) 2.87
Activation of transcription factor IIIC by the adenovirus E1A protein. Cell (1988) 2.86
HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev (1992) 2.85
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Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. J Biol Chem (1986) 2.78
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc Natl Acad Sci U S A (1998) 2.76
Multiple factors involved in the transcription of class III genes in Xenopus laevis. J Biol Chem (1982) 2.75
Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol Cell Biol (1995) 2.74
A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol Cell (1999) 2.71
Phosphorylation of serum response factor, a factor that binds to the serum response element of the c-FOS enhancer. Proc Natl Acad Sci U S A (1988) 2.70
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Mol Cell Biol (1986) 2.69
HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol Cell (2000) 2.68
Purification of the c-fos enhancer-binding protein. Mol Cell Biol (1987) 2.64
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes Dev (1988) 2.60
Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature (1996) 2.58
Association of a 5S gene transcription factor with 5S RNA and altered levels of the factor during cell differentiation. Cell (1980) 2.58
Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. EMBO J (1993) 2.56
Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation. Cell (1983) 2.54
The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature (1993) 2.50
Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes Dev (1988) 2.47
Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol Cell Biol (1992) 2.47
Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes Dev (1996) 2.45
Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J (1993) 2.45
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors. Cell (1992) 2.43
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A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID. J Biol Chem (1998) 2.40
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Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization. EMBO J (1986) 2.38
Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Mol Cell Biol (1984) 2.38
Proximal sequence element-binding transcription factor (PTF) is a multisubunit complex required for transcription of both RNA polymerase II- and RNA polymerase III-dependent small nuclear RNA genes. Mol Cell Biol (1995) 2.33
Low molecular weight viral RNAs transcribed by RNA polymerase III during adenovirus 2 infection. Cell (1976) 2.33