Identification of a putative microvascular oxygen sensor.

PubWeight™: 1.30‹?› | Rank: Top 10%

🔗 View Article (PMID 8925569)

Published in Circ Res on July 01, 1996

Authors

D R Harder1, J Narayanan, E K Birks, J F Liard, J D Imig, J H Lombard, A R Lange, R J Roman

Author Affiliations

1: Department of Physiology, Medical College of Wisconsin, Milwaukee 53226, USA.

Articles citing this

Glial and neuronal control of brain blood flow. Nature (2010) 6.61

Tone-dependent vascular responses to astrocyte-derived signals. Am J Physiol Heart Circ Physiol (2008) 1.48

Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: role of tissue hypoxia. J Physiol (2000) 1.39

Oxygen modulation of neurovascular coupling in the retina. Proc Natl Acad Sci U S A (2011) 1.17

Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat preglomerular microvessels (PGMV) via A2A receptors. Br J Pharmacol (2004) 1.14

Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. Am J Physiol Renal Physiol (2009) 1.09

Multifunctional role of astrocytes as gatekeepers of neuronal energy supply. Front Cell Neurosci (2013) 1.00

Role of 20-HETE in the pial arteriolar constrictor response to decreased hematocrit after exchange transfusion of cell-free polymeric hemoglobin. J Appl Physiol (1985) (2005) 1.00

Cytochrome P450 drives a HIF-regulated behavioral response to reoxygenation by C. elegans. Science (2013) 0.94

Inhibition of 20-HETE attenuates diabetes-induced decreases in retinal hemodynamics. Exp Eye Res (2011) 0.93

Hypoxia does not activate ATP-sensitive K+ channels in arteriolar muscle cells. Microcirculation (2000) 0.92

Simple method for preparing poly(ethylene glycol)-surface-conjugated liposome-encapsulated hemoglobins: physicochemical properties, long-term storage stability, and their reactions with O2, CO, and NO. Langmuir (2011) 0.88

Attenuation of neonatal ischemic brain damage using a 20-HETE synthesis inhibitor. J Neurochem (2012) 0.87

20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels. PLoS One (2013) 0.87

Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. Microcirculation (2009) 0.86

Endothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusion. Am J Physiol Regul Integr Comp Physiol (2009) 0.84

Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles. Prostaglandins Other Lipid Mediat (2013) 0.84

Functional vasodilation in the rat spinotrapezius muscle: role of nitric oxide, prostanoids and epoxyeicosatrienoic acids. Clin Exp Pharmacol Physiol (2008) 0.84

Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. Microcirculation (2010) 0.84

Arteriolar oxygen reactivity: where is the sensor and what is the mechanism of action? J Physiol (2016) 0.83

Onset of pulmonary ventilation in fetal sheep produces pial arteriolar constriction dependent on cytochrome p450 omega-hydroxylase activity. J Appl Physiol (1985) (2010) 0.81

Significance of K(ATP) channels, L-type Ca²⁺ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles in vivo. BMC Physiol (2013) 0.77

CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. Microvasc Res (2009) 0.76

Blood viscosity modulates tissue perfusion: sometimes and somewhere. Transfus Altern Transfus Med (2008) 0.75

Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target. Pharmaceutics (2017) 0.75

Insensitivity of cerebral oxygen transport to oxygen affinity of hemoglobin-based oxygen carriers. Biochim Biophys Acta (2008) 0.75

The Reactivity of Polymersome Encapsulated Hemoglobin with Physiologically Important Gaseous Ligands: Oxygen, Carbon Monoxide and Nitric Oxide. Macromolecules (2012) 0.75

Hyperoxia does not directly affect vascular tone in isolated arteries from mice. PLoS One (2017) 0.75

Articles by these authors

Paracrine regulation of the renal microcirculation. Physiol Rev (1996) 2.86

Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res (2000) 2.67

Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. Am J Physiol (1999) 2.12

A genomic-systems biology map for cardiovascular function. Science (2001) 2.09

Receptor-mediated intrarenal angiotensin II augmentation in angiotensin II-infused rats. Hypertension (1996) 2.02

Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99

Role of baroreceptor reflex in daily control of arterial blood pressure and other variables in dogs. Circ Res (1973) 1.95

The role of the kidney in hypertension. JAMA (1996) 1.80

Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol (1992) 1.80

Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J Vasc Res (1995) 1.76

Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke (1996) 1.68

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci U S A (2001) 1.61

Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke (1998) 1.58

Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol (1994) 1.57

Renal accumulation of circulating angiotensin II in angiotensin II-infused rats. Hypertension (1996) 1.55

Intrarenal production of angiotensin II. Semin Nephrol (1997) 1.55

Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol (1996) 1.53

Actions of epoxygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol (1996) 1.50

Consomic rat model systems for physiological genomics. Acta Physiol Scand (2004) 1.50

20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ Res (1993) 1.48

Vascular muscle cell depolarization and activation in renal arteries on elevation of transmural pressure. Am J Physiol (1987) 1.48

Genetic contamination of Dahl SS/Jr rats. Impact on studies of salt-sensitive hypertension. Hypertension (1994) 1.48

Stress failure of pulmonary capillaries in racehorses with exercise-induced pulmonary hemorrhage. J Appl Physiol (1985) (1993) 1.47

Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor. Am J Hypertens (1998) 1.47

The renal medulla and hypertension. Hypertension (1995) 1.46

20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles. Am J Physiol (1996) 1.46

Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension. Kidney Int (2007) 1.39

Malaria prophylaxis--the South African viewpoint. S Afr Med J (1993) 1.38

Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. J Pharmacol Exp Ther (1994) 1.38

Skeletal muscle mitochondrial myopathy as a cause of exercise intolerance in a horse. Muscle Nerve (1994) 1.37

Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase. Anesth Analg (2000) 1.37

20-HETE agonists and antagonists in the renal circulation. Am J Physiol (1999) 1.37

20-Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C. J Biol Chem (1997) 1.36

Hybrid fuzzy logic committee neural networks for recognition of swallow acceleration signals. Comput Methods Programs Biomed (2001) 1.36

Neuronal nitric oxide synthase modulates rat renal microvascular function. Am J Physiol (1998) 1.34

Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. Am J Physiol (1996) 1.33

Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am J Physiol (1994) 1.32

Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats. Stroke (1997) 1.32

Hyponatremia in cirrhosis: from pathogenesis to treatment. Hepatology (1998) 1.27

Role of nitric oxide in renal papillary blood flow and sodium excretion. Hypertension (1992) 1.26

Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca2+ current. J Physiol (1998) 1.24

Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. Hypertension (1999) 1.24

Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol (1996) 1.24

Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. J Appl Physiol (1985) (1986) 1.21

Intrarenal angiotensin II generation and renal effects of AT1 receptor blockade. J Am Soc Nephrol (1999) 1.21

Characterization of a new model for the study of pressure-natriuresis in the rat. Am J Physiol (1985) 1.19

Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor. J Pharmacol Exp Ther (1990) 1.19

Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension (1997) 1.18

Role of 20-HETE in elevating chloride transport in the thick ascending limb of Dahl SS/Jr rats. Hypertension (1999) 1.17

Response of extraparenchymal resistance arteries of rat skeletal muscle to reduced PO2. Am J Physiol (1994) 1.17

Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. Am J Physiol (1999) 1.17

Microvascular rarefaction and tissue vascular resistance in hypertension. Am J Physiol (1989) 1.16

Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am J Physiol (1994) 1.16

Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat. Kidney Int (2000) 1.15

Hemodynamic effects of exogenous and endogenous vasopressin at low plasma concentrations in conscious dogs. Circ Res (1980) 1.15

Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. Trends Cardiovasc Med (2001) 1.12

Cardiac output distribution during vasopressin infusion or dehydration in conscious dogs. Am J Physiol (1982) 1.12

Localization of cytochrome P-450 4A isoforms along the rat nephron. Am J Physiol (1998) 1.12

Role of endothelium and arterial K+ channels in mediating hypoxic dilation of middle cerebral arteries. Am J Physiol (1994) 1.12

Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles. Circ Res (1998) 1.12

Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. Am J Physiol (1998) 1.11

Epoxyeicosatrienoic acid analogs and vascular function. Curr Med Chem (2010) 1.11

Renin gene transfer restores angiogenesis and vascular endothelial growth factor expression in Dahl S rats. Hypertension (2001) 1.11

Role of cytochrome P450 metabolites of arachidonic acid in hypertension. Curr Drug Metab (2004) 1.09

Abnormal renal hemodynamics and pressure-natriuresis relationship in Dahl salt-sensitive rats. Am J Physiol (1986) 1.09

Role of blood volume expansion in Dahl rat model of hypertension. Am J Physiol (1990) 1.09

Systems analysis of arterial pressure regulation and hypertension. Ann Biomed Eng (1972) 1.09

Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res (1997) 1.08

Role of renal nerves in afferent arteriolar reactivity in angiotensin-induced hypertension. Hypertension (1997) 1.08

Localization of the ANG II type 2 receptor in the microcirculation of skeletal muscle. Am J Physiol (1998) 1.07

Vasopressin in cardiovascular control: role of circulating vasopressin. Clin Sci (Lond) (1984) 1.07

Pressure-diuresis in volume-expanded rats. Cortical and medullary hemodynamics. Hypertension (1988) 1.06

Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats. Am J Physiol (1994) 1.06

Coexistence of two types of Ca(2+)-activated K+ channels in rat renal arterioles. Am J Physiol (1996) 1.06

Elevated salt intake impairs dilation of rat skeletal muscle resistance arteries via ANG II suppression. Am J Physiol Heart Circ Physiol (2000) 1.05

Regulation of P-450 4A activity in the glomerulus of the rat. Am J Physiol (1999) 1.04

Fluorometric assay for urea in urine, plasma, and tubular fluid. Anal Biochem (1979) 1.04

High-salt diet and hypertension: focus on the renin-angiotensin system. Kidney Blood Press Res (2010) 1.04

Impaired autoregulation of renal blood flow in the fawn-hooded rat. Am J Physiol (1999) 1.04

Hypoxia increases the activity of Ca(2+)-sensitive K+ channels in cat cerebral arterial muscle cell membranes. Pflugers Arch (1994) 1.04

Kidney CYP450 enzymes: biological actions beyond drug metabolism. Curr Drug Metab (2003) 1.04

Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries. Am J Physiol Heart Circ Physiol (2000) 1.03

Cytochrome P4504A genotype cosegregates with hypertension in Dahl S rats. Hypertension (1996) 1.03

Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats. Hypertension (1996) 1.03

Effects of lipid-lowering agents in the Dahl salt-sensitive rat. Hypertension (1998) 1.03

Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol (2001) 1.03

Renal autoregulation in P2X1 knockout mice. Acta Physiol Scand (2004) 1.03