The 2.8 A crystal structure of Gla-domainless activated protein C.

PubWeight™: 1.56‹?› | Rank: Top 4%

🔗 View Article (PMC 452507)

Published in EMBO J on December 16, 1996

Authors

T Mather1, V Oganessyan, P Hof, R Huber, S Foundling, C Esmon, W Bode

Author Affiliations

1: Abteilung Strukturforschung, Max Planck Institut für Biochemie, Martinsried, Germany.

Articles citing this

Proteases involved in cartilage matrix degradation in osteoarthritis. Biochim Biophys Acta (2011) 1.73

Exosites in the substrate specificity of blood coagulation reactions. J Thromb Haemost (2007) 1.61

Cytoprotective protein C pathways and implications for stroke and neurological disorders. Trends Neurosci (2011) 1.53

Regulation of the protein C anticoagulant and antiinflammatory pathways. Curr Med Chem (2010) 1.48

Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant. Blood (2009) 1.36

Identification of functional endothelial protein C receptor in human plasma. J Clin Invest (1997) 1.31

Protein C anticoagulant and cytoprotective pathways. Int J Hematol (2012) 1.14

Structure of human factor VIIa and its implications for the triggering of blood coagulation. Proc Natl Acad Sci U S A (1999) 1.12

Zymogenic and enzymatic properties of the 70-80 loop mutants of factor X/Xa. Protein Sci (2004) 1.12

Recombinant human activated protein C inhibits integrin-mediated neutrophil migration. Blood (2009) 1.11

Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle. EMBO J (2000) 1.09

Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA. EMBO J (1997) 1.08

Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc Natl Acad Sci U S A (1998) 1.07

Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin. Proc Natl Acad Sci U S A (2003) 1.07

Engineering the proteolytic specificity of activated protein C improves its pharmacological properties. Proc Natl Acad Sci U S A (2003) 1.05

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants. EMBO J (1997) 0.99

Activated protein C action in inflammation. Br J Haematol (2009) 0.98

Some antiphospholipid antibodies recognize conformational epitopes shared by beta2-glycoprotein I and the homologous catalytic domains of several serine proteases. Arthritis Rheum (2007) 0.95

Capturing spontaneous partitioning of peripheral proteins using a biphasic membrane-mimetic model. J Phys Chem B (2011) 0.95

Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C. Proc Natl Acad Sci U S A (2006) 0.94

Identification of polyclonal and monoclonal antibodies against tissue plasminogen activator in the antiphospholipid syndrome. Arthritis Rheum (2005) 0.92

Modeling zymogen protein C. Biophys J (2000) 0.92

ProCMD: a database and 3D web resource for protein C mutants. BMC Bioinformatics (2007) 0.91

A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C. Arthritis Rheum (2003) 0.89

Activated protein C: a potential cardioprotective factor against ischemic injury during ischemia/reperfusion. Am J Transl Res (2009) 0.88

Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells. J Biol Chem (2010) 0.86

Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S. Biochem J (2000) 0.85

Antibodies against the activated coagulation factor X (FXa) in the antiphospholipid syndrome that interfere with the FXa inactivation by antithrombin. J Immunol (2006) 0.84

Structural investigation of the A domains of human blood coagulation factor V by molecular modeling. Protein Sci (1998) 0.84

Cytoprotective-selective activated protein C therapy for ischaemic stroke. Thromb Haemost (2014) 0.84

New enzyme lineages by subdomain shuffling. Proc Natl Acad Sci U S A (1998) 0.81

Mutagenesis studies toward understanding allostery in thrombin. Biochemistry (2009) 0.81

Inhibition of thrombin formation by active site mutated (S360A) activated protein C. J Biol Chem (2010) 0.80

Expression and functional characterisation of natural R147W and K150del variants of protein C in the Chinese population. Thromb Haemost (2013) 0.80

Function of the activated protein C (APC) autolysis loop in activated FVIII inactivation. Br J Haematol (2011) 0.79

Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies. Biologics (2009) 0.79

The role of P4-P3' residues flanking Arg336 in facilitating activated protein C-catalyzed cleavage and inactivation of factor VIIIa. Thromb Res (2011) 0.79

The functional significance of the autolysis loop in protein C and activated protein C. Thromb Haemost (2005) 0.79

Design and characterization of an APC-specific serpin for the treatment of hemophilia. Blood (2016) 0.79

Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling. Protein Sci (2008) 0.78

Know your APC. Blood (2009) 0.78

Contribution of factor VIII light-chain residues 2007-2016 to an activated protein C-interactive site. Thromb Haemost (2012) 0.77

Screening the molecular surface of human anticoagulant protein C: a search for interaction sites. J Comput Aided Mol Des (2001) 0.77

Down-regulation of the clotting cascade by the protein C pathway. Hematol Educ (2013) 0.77

Autolysis loop restricts the specificity of activated protein C: analysis by FRET and functional assays. Biophys Chem (2008) 0.77

Plasmin immunization preferentially induces potentially prothrombotic IgG anticardiolipin antibodies in MRL/MpJ mice. Arthritis Rheum (2009) 0.76

Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs. Intrinsically Disord Proteins (2014) 0.75

Structure-Function Relationship of the Interaction between Tissue Factor and Factor VIIa. Semin Thromb Hemost (2015) 0.75

Variable contributions of basic residues forming an APC exosite in the binding and inactivation of factor VIIIa. Biochemistry (2013) 0.75

Articles cited by this

Database of homology-derived protein structures and the structural meaning of sequence alignment. Proteins (1991) 32.50

On the size of the active site in proteases. I. Papain. Biochem Biophys Res Commun (1967) 18.32

Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature (1994) 9.06

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. J Mol Graph (1993) 7.31

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization. J Biol Chem (1976) 3.57

Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem (1992) 3.27

The roles of protein C and thrombomodulin in the regulation of blood coagulation. J Biol Chem (1989) 3.14

The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci (1992) 3.03

Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif. Trends Biochem Sci (1991) 2.62

Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem (1994) 2.52

The nucleotide sequence of the gene for human protein C. Proc Natl Acad Sci U S A (1985) 2.24

The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0. J Mol Biol (1975) 2.24

Structure of human des(1-45) factor Xa at 2.2 A resolution. J Mol Biol (1993) 2.07

Proteolytic formation and properties of gamma-carboxyglutamic acid-domainless protein C. J Biol Chem (1983) 1.77

The mechanism of inactivation of human factor V and human factor Va by activated protein C. J Biol Chem (1994) 1.65

Inflammation and coagulation: linked processes potentially regulated through a common pathway mediated by protein C. Thromb Haemost (1991) 1.59

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B. Proc Natl Acad Sci U S A (1995) 1.58

Generation of fibrinolytic activity by infusion of activated protein C into dogs. J Clin Invest (1981) 1.50

Amino acid sequence of the heavy chain of bovine protein C. J Biol Chem (1982) 1.50

Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin. Proc Natl Acad Sci U S A (1991) 1.46

Glycosylation of human protein C affects its secretion, processing, functional activities, and activation by thrombin. J Biol Chem (1991) 1.46

Characterization of a cDNA coding for human protein C. Proc Natl Acad Sci U S A (1984) 1.45

The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci (1994) 1.44

Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface. FASEB J (1995) 1.36

Protein C deficiency: a database of mutations, 1995 update. On behalf of the Subcommittee on Plasma Coagulation Inhibitors of the Scientific and Standardization Committee of the ISTH. Thromb Haemost (1995) 1.36

Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies. Semin Thromb Hemost (1990) 1.33

Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci U S A (1985) 1.27

Activated protein C-catalyzed inactivation of human factor VIII and factor VIIIa. Identification of cleavage sites and correlation of proteolysis with cofactor activity. J Biol Chem (1991) 1.24

Activation of purified prothrombin to autoprothrombin I or autoprothrombin II (platelet cofactor II or autoprothrombin II-A). Thromb Diath Haemorrh (1960) 1.23

Protein C activation. Methods Enzymol (1993) 1.21

Kinetics of the heparin-enhanced antithrombin III/thrombin reaction. Evidence for a template model for the mechanism of action of heparin. J Biol Chem (1982) 1.19

Human protein C inhibits selectin-mediated cell adhesion: role of unique fucosylated oligosaccharide. Glycobiology (1994) 1.17

Amino acid sequence of the light chain of bovine protein C. J Biol Chem (1982) 1.12

Specificity of activated human protein C. Biochem J (1985) 1.06

Identification of a sequence of human activated protein C (residues 390-404) essential for its anticoagulant activity. J Biol Chem (1991) 1.01

Treatment of purpura fulminans in meningococcemia with protein C concentrate. J Pediatr (1995) 0.99

A novel exosite in the light chain of human activated protein C essential for interaction with blood coagulation factor Va. Biochemistry (1993) 0.98

A comparison of three heparin-binding serine proteinase inhibitors. J Biol Chem (1992) 0.96

Relationship of "new" vitamin K-dependent Protein C and "old" autoprothrombin II-a. Thromb Res (1976) 0.94

Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex. J Biol Chem (1994) 0.93

Identification of divalent metal ion-dependent inhibition of activated protein C by alpha 2-macroglobulin and alpha 2-antiplasmin in blood and comparisons to inhibition of factor Xa, thrombin, and plasmin. J Biol Chem (1991) 0.91

Conversion of glutamic acid 192 to glutamine in activated protein C changes the substrate specificity and increases reactivity toward macromolecular inhibitors. J Biol Chem (1993) 0.91

Glu192-->Gln substitution in thrombin yields an enzyme that is effectively inhibited by bovine pancreatic trypsin inhibitor and tissue factor pathway inhibitor. J Biol Chem (1994) 0.91

Alteration of the substrate and inhibitor specificities of blood coagulation factor VIIa: importance of amino acid residue K192. Biochemistry (1995) 0.90

Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex. Biochemistry (1995) 0.89

Contribution of residue 192 in factor Xa to enzyme specificity and function. J Biol Chem (1995) 0.88

Interaction of activated protein C with serpins. Biochem J (1993) 0.83

Interactions and inhibition of blood coagulation factor Va involving residues 311-325 of activated protein C. Protein Sci (1993) 0.82

Resistance to inhibition by alpha-1-anti-trypsin and species specificity of a chimeric human/bovine protein C. Biochemistry (1994) 0.82

Activation of protein C and its distribution between its inhibitors, protein C inhibitor, alpha 1-antitrypsin and alpha 2-macroglobulin, in patients with disseminated intravascular coagulation. Thromb Haemost (1993) 0.81

Thrombophilia: the discovery of activated protein C resistance. Adv Genet (1995) 0.81

A comparative study of partial primary structures of the catalytic region of mammalian protein C. Br J Haematol (1994) 0.79

Articles by these authors

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science (1995) 12.94

Structure of 20S proteasome from yeast at 2.4 A resolution. Nature (1997) 12.73

X-ray structure analysis of a membrane protein complex. Electron density map at 3 A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis. J Mol Biol (1984) 8.85

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature (1998) 7.77

A gated channel into the proteasome core particle. Nat Struct Biol (2000) 5.42

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution. Nature (2012) 5.22

Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49

Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography. Opt Express (2006) 4.49

The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature (2000) 4.46

Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. J Mol Biol (1984) 4.14

Proteasome from Thermoplasma acidophilum: a threonine protease. Science (1995) 3.62

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function. J Mol Biol (1984) 3.60

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. Nature (2000) 3.53

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. J Mol Biol (1982) 3.28

Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem (1992) 3.27

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity. J Mol Biol (2003) 3.25

Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. J Mol Biol (1980) 3.25

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. J Mol Biol (1974) 3.17

The anterior cingulate cortex. The evolution of an interface between emotion and cognition. Ann N Y Acad Sci (2001) 3.14

The proteasome. Annu Rev Biophys Biomol Struct (1999) 3.13

Crystallographic structure studies of an IgG molecule and an Fc fragment. Nature (1976) 3.00

Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT. Cell (1998) 2.94

Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat Struct Biol (2000) 2.82

Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster. Science (2001) 2.78

The structure of a complex of recombinant hirudin and human alpha-thrombin. Science (1990) 2.71

Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus. EMBO J (2000) 2.71

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J Mol Biol (1993) 2.66

The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases. Protein Sci (1995) 2.63

Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24). EMBO J (1993) 2.54

Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52

Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. Opt Express (2005) 2.48

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. EMBO J (1988) 2.48

Primary structure of human neutrophil elastase. Proc Natl Acad Sci U S A (1987) 2.45

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. EMBO J (1990) 2.44

High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli. Eur J Biochem (1995) 2.44

X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. J Mol Biol (1985) 2.42

Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science (1994) 2.41

The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships. Eur J Biochem (1990) 2.37

X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function. Eur J Biochem (1994) 2.37

The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution. EMBO J (1991) 2.36

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology (2001) 2.36

The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett (1991) 2.33

The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0. J Mol Biol (1975) 2.24

Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip. J Mol Biol (1991) 2.19

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc Natl Acad Sci U S A (1999) 2.19

Refined crystal structure of ascorbate oxidase at 1.9 A resolution. J Mol Biol (1992) 2.18

Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (1997) 2.17

Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proc Natl Acad Sci U S A (1986) 2.16

Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci U S A (2001) 2.14

Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic archaeum. Appl Environ Microbiol (1993) 2.13

Structure of human des(1-45) factor Xa at 2.2 A resolution. J Mol Biol (1993) 2.07

Refined structure of the hirudin-thrombin complex. J Mol Biol (1991) 2.06

Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. J Mol Biol (1987) 2.06

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Nature (2000) 2.04

Crystal structure of a DNA-dependent RNA polymerase (DNA primase). Nat Struct Biol (2001) 2.03

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases. Nature (1992) 2.02

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity. EMBO J (1991) 1.99

Structural and functional aspects of domain motions in proteins. CRC Crit Rev Biochem (1984) 1.99

The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. Biochemistry (1975) 1.98

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution. J Mol Biol (1978) 1.95

Lesions of the posterior paraventricular thalamus block habituation of hypothalamic-pituitary-adrenal responses to repeated restraint. J Neuroendocrinol (2002) 1.91

X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands. J Mol Biol (1989) 1.90

Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 A resolution. Structure solution, crystallographic refinement and preliminary structural interpretation. J Mol Biol (1982) 1.90

The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action. Nat Struct Biol (1998) 1.85

Mistletoe therapy in oncology. Cochrane Database Syst Rev (2008) 1.84

The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain. J Mol Biol (1996) 1.82

Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. J Mol Biol (1985) 1.81

Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold. EMBO J (1999) 1.79

Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. J Mol Biol (1977) 1.79

Mutational studies on HslU and its docking mode with HslV. Proc Natl Acad Sci U S A (2000) 1.79

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. EMBO J (1998) 1.79

Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor. J Mol Biol (1987) 1.77

Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. Eur J Biochem (1974) 1.76

X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J (1986) 1.76

Crystal structure of heat shock locus V (HslV) from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.75

Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered Fourier Domain Mode Locked laser. Opt Express (2007) 1.75

The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry. Eur J Biochem (1987) 1.75

Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas. Science (1995) 1.74

Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution. J Mol Biol (1992) 1.73

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region. J Mol Biol (1973) 1.73