Published in J Biol Chem on March 21, 1997
Activity-based protein profiling: the serine hydrolases. Proc Natl Acad Sci U S A (1999) 5.43
Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J Clin Invest (2009) 2.66
Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model. PLoS One (2009) 2.47
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35
Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer. Hum Pathol (2013) 2.06
The metabolic serine hydrolases and their functions in mammalian physiology and disease. Chem Rev (2011) 1.89
Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy. Mol Cancer Ther (2012) 1.48
Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin. Mol Cancer Ther (2009) 1.20
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites. Biochemistry (2007) 1.16
Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions. Proc Natl Acad Sci U S A (1998) 1.16
The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices. Cancer Res (2006) 1.15
Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases. PLoS One (2011) 1.11
Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV. Arch Biochem Biophys (2006) 1.09
Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clin Exp Metastasis (2011) 0.97
Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis. Arthritis Res Ther (2006) 0.97
U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3. Cancer Cell Int (2005) 0.96
Dipeptidyl peptidase IV (DPPIV) inhibits cellular invasion of melanoma cells. Clin Exp Metastasis (2000) 0.89
Activation of EDTA-resistant gelatinases in malignant human tumors. Cancer Res (2006) 0.88
Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells. Clin Exp Metastasis (2003) 0.86
Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours. Histopathology (2009) 0.86
Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells. Int J Cancer (2009) 0.85
Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-β signaling. J Biol Chem (2014) 0.84
Fibroblast activation protein α in tumor microenvironment: recent progression and implications (review). Mol Med Rep (2015) 0.79
Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathway. Cancer Biol Ther (2014) 0.78
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J Biol Chem (2015) 0.76
Fibroblast activation protein is dispensable in the anti-influenza immune response in mice. PLoS One (2017) 0.75
The application of the fibroblast activation protein α-targeted immunotherapy strategy. Oncotarget (2016) 0.75
Proteolytic Enzymes Clustered in Specialized Plasma-Membrane Domains Drive Endothelial Cells' Migration. PLoS One (2016) 0.75
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents. J Clin Invest (2017) 0.75
Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP). Sci Rep (2017) 0.75
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol (2001) 5.78
Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. Development (1999) 4.21
Immunoelectron microscopic studies of the sites of cell-substratum and cell-cell contacts in cultured fibroblasts. J Cell Biol (1982) 3.92
Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization. J Cell Biol (1989) 3.77
Purification on renografin density gradients of Chlamydia trachomatis grown in the yolk sac of eggs. Appl Microbiol (1974) 3.64
Development of cell surface linkage complexes in cultured fibroblasts. J Cell Biol (1985) 3.59
Mechanism of retraction of the trailing edge during fibroblast movement. J Cell Biol (1981) 3.49
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J Biol Chem (1990) 3.25
One-dimensional electrical contact to a two-dimensional material. Science (2013) 2.87
The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle. J Cell Biol (1999) 2.82
Processive translocation and DNA unwinding by individual RecBCD enzyme molecules. Nature (2001) 2.78
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment. Oncogene (2000) 2.71
Confirmatory assay increases specificity of the chlamydiazyme test for Chlamydia trachomatis infection of the cervix. J Clin Microbiol (1990) 2.65
Botulinum toxin for diabetic neuropathic pain: a randomized double-blind crossover trial. Neurology (2009) 2.63
cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors. Proc Natl Acad Sci U S A (1986) 2.58
LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell (1995) 2.37
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35
Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs. J Biol Chem (1987) 2.29
Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts. J Biol Chem (1988) 2.23
Lumbosacral transitional vertebrae and their relationship with lumbar extradural defects. Spine (Phila Pa 1976) (1984) 2.21
Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol (2008) 2.11
Force-velocity relationships in kinesin-driven motility. Nature (1993) 2.10
Homing receptors and vascular addressins: cell adhesion molecules that direct lymphocyte traffic. Immunol Rev (1989) 2.06
A polypeptide bacteriophage receptor: modified cell wall protein subunits in bacteriophage-resistant mutants of Bacillus sphaericus strain P-1. J Bacteriol (1973) 2.00
Review of clinical budgeting and costing experiments. Br Med J (Clin Res Ed) (1983) 2.00
Merosin, a tissue-specific basement membrane protein, is a laminin-like protein. Proc Natl Acad Sci U S A (1990) 1.93
Recombinant antigens to detect Toxoplasma gondii-specific immunoglobulin G and immunoglobulin M in human sera by enzyme immunoassay. J Clin Microbiol (2000) 1.92
Induction of spreading during fibroblast movement. J Cell Biol (1979) 1.90
A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein. J Biol Chem (1992) 1.89
The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration. Neuron (2000) 1.88
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia. J Biol Chem (1998) 1.87
BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study. Cancer Res (2000) 1.83
Characterization of a membrane-associated glycoprotein complex implicated in cell adhesion to fibronectin. J Cell Biochem (1985) 1.79
Administrative registers in psychiatric research: a systematic review of validity studies. Acta Psychiatr Scand (2005) 1.79
Theory of light diffraction by single skeletal muscle fibers. Biophys J (1980) 1.78
A light-scattering characterization of membrane vesicles. Biophys J (1976) 1.78
Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex. J Cell Biol (1986) 1.78
High copy number of the pUC plasmid results from a Rom/Rop-suppressible point mutation in RNA II. Mol Microbiol (1992) 1.77
Chromosome movement in mitosis requires microtubule anchorage at spindle poles. J Cell Biol (2001) 1.76
Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature. Neuroepidemiology (2013) 1.76
Fibronectin is not present in the focal adhesions formed between normal cultured fibroblasts and their substrata. Proc Natl Acad Sci U S A (1980) 1.76
Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen. J Biol Chem (1991) 1.74
Subunit structure of a laminin-binding integrin and localization of its binding site on laminin. J Biol Chem (1989) 1.73
Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites. J Cell Biol (1984) 1.71
Sarcomere length determination using laser diffraction. Effect of beam and fiber diameter. Biophys J (1984) 1.69
Effects of passive immunization in patients with the acquired immunodeficiency syndrome-related complex and acquired immunodeficiency syndrome. Proc Natl Acad Sci U S A (1988) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides. J Cell Biol (1988) 1.65
LDL receptor-related protein: a multiligand receptor for lipoprotein and proteinase catabolism. FASEB J (1995) 1.64
A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells. Cancer Res (1994) 1.63
Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J Cell Biol (1990) 1.63
Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res (1998) 1.62
Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides. J Cell Biol (1986) 1.62
Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin. J Cell Biol (1989) 1.60
Selection and validation of differentially expressed genes in head and neck cancer. Cell Mol Life Sci (2004) 1.58
A high prevalence of occludable angles in a Vietnamese population. Ophthalmology (1996) 1.58
A novel protease-docking function of integrin at invadopodia. J Biol Chem (1999) 1.58
Local degradation of fibronectin at sites of expression of the transforming gene product pp60src. Nature (1985) 1.55
Light diffraction study of single skeletal muscle fibres. Biophys J (1979) 1.54
Chronic daily headache in Taipei, Taiwan: prevalence, follow-up and outcome predictors. Cephalalgia (2001) 1.51
cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide. J Biol Chem (1986) 1.51
Immunocytochemical localization of 140 kD cell adhesion molecules in cultured chicken fibroblasts, and in chicken smooth muscle and intestinal epithelial tissues. J Histochem Cytochem (1985) 1.46
Difference in direct charge-parity violation between charged and neutral B meson decays. Nature (2008) 1.46
NuMA is a component of an insoluble matrix at mitotic spindle poles. Cell Motil Cytoskeleton (1999) 1.45
Rapid cellular translocation is related to close contacts formed between various cultured cells and their substrata. J Cell Sci (1982) 1.44
pH-dependent function, purification, and intracellular location of a major collagen-binding glycoprotein. J Cell Biol (1987) 1.43
Structural features of cartilage matrix protein deduced from cDNA. Proc Natl Acad Sci U S A (1987) 1.41
Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin. J Biol Chem (1995) 1.41
Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia. Cancer Res (1993) 1.41
Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors. Stem Cells Dev (2006) 1.41
The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin. J Cell Biol (1990) 1.40
Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility. J Cell Sci (2001) 1.40
Collective cell motion in endothelial monolayers. Phys Biol (2010) 1.39
Symptom burden and quality of life in end-stage renal disease: a study of 179 patients on dialysis and palliative care. Palliat Med (2009) 1.39
The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study. J Histochem Cytochem (1995) 1.39
Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells. J Cell Biol (1992) 1.39
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells. Proc Natl Acad Sci U S A (1990) 1.39
The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330. J Biol Chem (1992) 1.38
Clinical evaluation of the LeMaire anterior cruciate [correction of concrete] ligament lateral substitution procedure. A quality audit of the Leicester modification. Injury (1998) 1.38
Recent advances in research on fibronectin and other cell attachment proteins. J Cell Biochem (1985) 1.38
Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus. Am J Hum Genet (1992) 1.37
Identification of DNA methylation markers for human breast carcinomas using the methylation-sensitive restriction fingerprinting technique. Cancer Res (1997) 1.37
Development of the aortic vessel wall as defined by vascular smooth muscle and extracellular matrix markers. Dev Biol (1996) 1.34
A Kazal-type inhibitor with thrombin specificity from Rhodnius prolixus. J Biol Chem (1993) 1.34
Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex. Mol Cell Biol (1994) 1.32
Transmission of HIV to heterosexual partners of infected men and women. AIDS (1989) 1.32
Ice growth in supercooled solutions of antifreeze glycoprotein. Nature (1987) 1.31
Induction of antibodies against GD3 ganglioside in melanoma patients by vaccination with GD3-lactone-KLH conjugate plus immunological adjuvant QS-21. Int J Cancer (2000) 1.30
Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1. J Cell Biol (1995) 1.30
The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor. J Biol Chem (1994) 1.30
Antifreeze glycoproteins from polar fish blood. Annu Rev Biophys Biophys Chem (1986) 1.29