A novel protease-docking function of integrin at invadopodia.

PubWeight™: 1.58‹?› | Rank: Top 4%

🔗 View Article (PMID 10455171)

Published in J Biol Chem on August 27, 1999

Authors

S C Mueller1, G Ghersi, S K Akiyama, Q X Sang, L Howard, M Pineiro-Sanchez, H Nakahara, Y Yeh, W T Chen

Author Affiliations

1: Lombardi Cancer Center and Department of Cell Biology, Georgetown University Medical Center, Washington, D. C. 20007, USA.

Articles citing this

LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol Rev (2008) 3.46

Invadopodia: specialized cell structures for cancer invasion. Clin Exp Metastasis (2006) 3.05

The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39

Mapping proteolytic cancer cell-extracellular matrix interfaces. Clin Exp Metastasis (2008) 1.83

N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells. Cell Motil Cytoskeleton (2009) 1.54

Fascin: Invasive filopodia promoting metastasis. Commun Integr Biol (2010) 1.49

ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol (2002) 1.48

Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients. Int J Cancer (2010) 1.31

ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis. Semin Cell Dev Biol (2010) 1.30

β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell (2013) 1.29

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells. BMC Cancer (2011) 1.24

Adhesion rings surround invadopodia and promote maturation. Biol Open (2012) 1.23

Signaling inputs to invadopodia and podosomes. J Cell Sci (2013) 1.18

The protease complex consisting of dipeptidyl peptidase IV and seprase plays a role in the migration and invasion of human endothelial cells in collagenous matrices. Cancer Res (2006) 1.15

Invading one step at a time: the role of invadopodia in tumor metastasis. Oncogene (2013) 1.13

Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells. Curr Biol (2013) 1.11

The regulation of MMP targeting to invadopodia during cancer metastasis. Front Cell Dev Biol (2015) 1.11

Invadopodia and matrix degradation, a new property of prostate cancer cells during migration and invasion. J Biol Chem (2008) 1.10

Insidious changes in stromal matrix fuel cancer progression. Mol Cancer Res (2014) 1.09

Regulation of cancer invasiveness by the physical extracellular matrix environment. Cell Adh Migr (2009) 1.09

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol (2015) 1.07

Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia. J Cell Mol Med (2009) 1.03

Physiological type I collagen organization induces the formation of a novel class of linear invadosomes. Mol Biol Cell (2011) 1.01

Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol (2014) 1.01

Digging a little deeper: the stages of invadopodium formation and maturation. Eur J Cell Biol (2014) 1.00

Cancer cell invasion is enhanced by applied mechanical stimulation. PLoS One (2011) 0.99

Laminin-332-beta1 integrin interactions negatively regulate invadopodia. J Cell Physiol (2010) 0.98

Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions. Clin Exp Metastasis (2011) 0.97

Syndecan-2 regulates the migratory potential of melanoma cells. J Biol Chem (2009) 0.95

Molecular mechanism for connective tissue destruction by dipeptidyl aminopeptidase IV produced by the periodontal pathogen Porphyromonas gingivalis. Infect Immun (2005) 0.90

Mesenchymal migration as a therapeutic target in glioblastoma. J Oncol (2010) 0.89

Activation of EDTA-resistant gelatinases in malignant human tumors. Cancer Res (2006) 0.88

MT-LOOP-dependent localization of membrane type I matrix metalloproteinase (MT1-MMP) to the cell adhesion complexes promotes cancer cell invasion. J Biol Chem (2013) 0.87

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation. Oncotarget (2015) 0.87

Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade. Cancer Res (2016) 0.87

Role of integrins in regulating proteases to mediate extracellular matrix remodeling. Cancer Microenviron (2012) 0.85

Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells. Int J Cancer (2009) 0.85

Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation. PLoS One (2014) 0.84

SNAP23, Syntaxin4, and vesicle-associated membrane protein 7 (VAMP7) mediate trafficking of membrane type 1-matrix metalloproteinase (MT1-MMP) during invadopodium formation and tumor cell invasion. Mol Biol Cell (2014) 0.84

The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion. Cell Adh Migr (2014) 0.83

Formation of atypical podosomes in extravillous trophoblasts regulates extracellular matrix degradation. Eur J Cell Biol (2012) 0.83

Cell polarity signaling in the plasticity of cancer cell invasiveness. Oncotarget (2016) 0.82

p53 in cell invasion, podosomes, and invadopodia. Cell Adh Migr (2014) 0.82

Identification and characterization of the promoter of fibroblast activation protein. Front Biosci (Elite Ed) (2010) 0.79

MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma. Arch Pathol Lab Med (2015) 0.79

5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion. J Cell Biol (2016) 0.78

Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis. Arthritis Res Ther (2015) 0.78

Regulation of invadopodia by mechanical signaling. Exp Cell Res (2015) 0.78

Expression levels of seprase/FAPα and DPPIV/CD26 in epithelial ovarian carcinoma. Oncol Lett (2015) 0.78

Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling. Mol Cell Proteomics (2016) 0.78

Flexible, actin-based ridges colocalise with the beta1 integrin on the surface of melanoma cells. Br J Cancer (2005) 0.77

Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways. Clin Exp Metastasis (2015) 0.77

Proteolytic Enzymes Clustered in Specialized Plasma-Membrane Domains Drive Endothelial Cells' Migration. PLoS One (2016) 0.75

Cadmium stimulates metastasis-associated phenotype in triple-negative breast cancer cells through integrin and β-catenin signaling. Toxicol Appl Pharmacol (2017) 0.75

β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells. PLoS One (2017) 0.75

Articles by these authors

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol (1995) 6.74

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science (1995) 6.45

Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. Development (1999) 4.21

Immunoelectron microscopic studies of the sites of cell-substratum and cell-cell contacts in cultured fibroblasts. J Cell Biol (1982) 3.92

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization. J Cell Biol (1989) 3.77

Purification on renografin density gradients of Chlamydia trachomatis grown in the yolk sac of eggs. Appl Microbiol (1974) 3.64

Development of cell surface linkage complexes in cultured fibroblasts. J Cell Biol (1985) 3.59

Mechanism of retraction of the trailing edge during fibroblast movement. J Cell Biol (1981) 3.49

Parallel neural networks for learning sequential procedures. Trends Neurosci (1999) 3.35

The kinesin-related protein, HSET, opposes the activity of Eg5 and cross-links microtubules in the mammalian mitotic spindle. J Cell Biol (1999) 2.82

Processive translocation and DNA unwinding by individual RecBCD enzyme molecules. Nature (2001) 2.78

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment. Oncogene (2000) 2.71

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex. J Exp Med (1989) 2.69

Confirmatory assay increases specificity of the chlamydiazyme test for Chlamydia trachomatis infection of the cervix. J Clin Microbiol (1990) 2.65

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion. J Cell Biol (1986) 2.63

Botulinum toxin for diabetic neuropathic pain: a randomized double-blind crossover trial. Neurology (2009) 2.63

Characterization of a 140-kD avian cell surface antigen as a fibronectin-binding molecule. J Cell Biol (1986) 2.62

Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion. J Biol Chem (1987) 2.52

Regulation of fibronectin receptor distribution. J Cell Biol (1992) 2.46

The interaction of plasma fibronectin with fibroblastic cells in suspension. J Biol Chem (1985) 2.44

Novel function for beta 1 integrins in keratinocyte cell-cell interactions. J Cell Biol (1990) 2.39

Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+. J Biol Chem (1995) 2.35

Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1. J Bacteriol (1979) 2.33

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts. J Biol Chem (1988) 2.23

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol (2008) 2.11

Force-velocity relationships in kinesin-driven motility. Nature (1993) 2.10

Mercury and cadmium resistances mediated by the penicillinase plasmid in Staphylococcus aureus. J Bacteriol (1974) 2.09

A polypeptide bacteriophage receptor: modified cell wall protein subunits in bacteriophage-resistant mutants of Bacillus sphaericus strain P-1. J Bacteriol (1973) 2.00

Review of clinical budgeting and costing experiments. Br Med J (Clin Res Ed) (1983) 2.00

Recombinant antigens to detect Toxoplasma gondii-specific immunoglobulin G and immunoglobulin M in human sera by enzyme immunoassay. J Clin Microbiol (2000) 1.92

Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1. J Bacteriol (1979) 1.90

Induction of spreading during fibroblast movement. J Cell Biol (1979) 1.90

The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration. Neuron (2000) 1.88

Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia. J Biol Chem (1998) 1.87

Characterization of a membrane-associated glycoprotein complex implicated in cell adhesion to fibronectin. J Cell Biochem (1985) 1.79

Administrative registers in psychiatric research: a systematic review of validity studies. Acta Psychiatr Scand (2005) 1.79

A light-scattering characterization of membrane vesicles. Biophys J (1976) 1.78

Theory of light diffraction by single skeletal muscle fibers. Biophys J (1980) 1.78

Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex. J Cell Biol (1986) 1.78

High copy number of the pUC plasmid results from a Rom/Rop-suppressible point mutation in RNA II. Mol Microbiol (1992) 1.77

Chromosome movement in mitosis requires microtubule anchorage at spindle poles. J Cell Biol (2001) 1.76

Fibronectin is not present in the focal adhesions formed between normal cultured fibroblasts and their substrata. Proc Natl Acad Sci U S A (1980) 1.76

Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies. J Cell Biol (1990) 1.75

Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites. J Cell Biol (1984) 1.71

In vivo biological behavior of a water-miscible fullerene: 14C labeling, absorption, distribution, excretion and acute toxicity. Chem Biol (1995) 1.69

Sarcomere length determination using laser diffraction. Effect of beam and fiber diameter. Biophys J (1984) 1.69

Formation of amyloid-like fibrils by self-association of a partially unfolded fibronectin type III module. J Mol Biol (1998) 1.69

Effects of passive immunization in patients with the acquired immunodeficiency syndrome-related complex and acquired immunodeficiency syndrome. Proc Natl Acad Sci U S A (1988) 1.69

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

Frequency of heavy-metal resistance in bacteria from inpatients in Japan. Nature (1977) 1.66

Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization. J Cell Biol (1999) 1.65

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells. Cancer Res (1994) 1.63

Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res (1998) 1.62

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides. J Cell Biol (1986) 1.62

Linkage of mercury, cadmium, and arsenate and drug resistance in clinical isolates of Pseudomonas aeruginosa. Appl Environ Microbiol (1977) 1.61

Synthetic peptides competitively inhibit both direct binding to fibroblasts and functional biological assays for the purified cell-binding domain of fibronectin. J Biol Chem (1985) 1.60

Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin. J Cell Biol (1989) 1.60

Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly. J Cell Biol (1991) 1.59

Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut (2005) 1.59

Selection and validation of differentially expressed genes in head and neck cancer. Cell Mol Life Sci (2004) 1.58

The interaction of fibronectin fragments with fibroblastic cells. J Biol Chem (1985) 1.58

Local degradation of fibronectin at sites of expression of the transforming gene product pp60src. Nature (1985) 1.55

A two-domain mechanism for group A streptococcal adherence through protein F to the extracellular matrix. EMBO J (1996) 1.54

Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the beta 1 subunit. FEBS Lett (1995) 1.54

Light diffraction study of single skeletal muscle fibres. Biophys J (1979) 1.54

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure. J Mol Biol (1998) 1.53

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas. J Clin Invest (1989) 1.52

Chronic daily headache in Taipei, Taiwan: prevalence, follow-up and outcome predictors. Cephalalgia (2001) 1.51

Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment. J Cell Biol (1988) 1.49

Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease. J Biol Chem (1997) 1.48

The inhibitory anti-beta1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function. J Biol Chem (1996) 1.47

Difference in direct charge-parity violation between charged and neutral B meson decays. Nature (2008) 1.46

Immunocytochemical localization of 140 kD cell adhesion molecules in cultured chicken fibroblasts, and in chicken smooth muscle and intestinal epithelial tissues. J Histochem Cytochem (1985) 1.46

NuMA is a component of an insoluble matrix at mitotic spindle poles. Cell Motil Cytoskeleton (1999) 1.45

Rapid cellular translocation is related to close contacts formed between various cultured cells and their substrata. J Cell Sci (1982) 1.44

pH-dependent function, purification, and intracellular location of a major collagen-binding glycoprotein. J Cell Biol (1987) 1.43

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia. Cancer Res (1993) 1.41

Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors. Stem Cells Dev (2006) 1.41

Hepatocellular carcinoma with intra-atrial tumor growth. A clinicopathologic study of 18 autopsy cases. Arch Pathol Lab Med (1984) 1.40

Symptom burden and quality of life in end-stage renal disease: a study of 179 patients on dialysis and palliative care. Palliat Med (2009) 1.39

Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells. J Cell Biol (1992) 1.39

Fibronectin. Adv Enzymol Relat Areas Mol Biol (1987) 1.39

Gene copy number effects in the mer operon of plasmid NR1. J Bacteriol (1979) 1.39

A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells. Proc Natl Acad Sci U S A (1990) 1.39

Clinical evaluation of the LeMaire anterior cruciate [correction of concrete] ligament lateral substitution procedure. A quality audit of the Leicester modification. Injury (1998) 1.38

Recent advances in research on fibronectin and other cell attachment proteins. J Cell Biochem (1985) 1.38

Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus. Am J Hum Genet (1992) 1.37

Identification and characterization of human endometase (Matrix metalloproteinase-26) from endometrial tumor. J Biol Chem (2000) 1.35